Ethanol-modulated cytokine production and expression in skin cells exposed to methotrexate

Skin Pharmacology and Applied Skin Physiology

Volumn 12, Issue 1-2, 1999, Pages 64-78

  Shear, Neil H ^b   Landau, Marina ^b   Malkiewicz, Izabella ^b   Katz, Gady G ^b   Neuman, Manuela G ^a  

^a SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^b NONE

Author keywords

Apoptosis; Cytotoxicity; Glutathione; Proinflammatory cytokines; Psoriasis

Indexed keywords

ALCOHOL; ANTIPSORIASIS AGENT; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; INTERLEUKIN 8; METHOTREXATE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ANTIBODY;

ALCOHOL CONSUMPTION; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG CYTOTOXICITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSORIASIS; SKIN CELL;

ANTIBODIES, MONOCLONAL; CELL LINE; CYTOKINES; DRUG INTERACTIONS; ETHANOL; GLUTATHIONE; HUMANS; INFANT, NEWBORN; METHOTREXATE; RNA; SKIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0033065771     PISSN: 14222868     EISSN: None     Source Type: Journal    
DOI: 10.1159/000029847     Document Type: Article

References (42)

1. Krueger GG, Duvic M: Epidemiology of Psoriasis: Clinical Issues. J Invest Dermatol 1994;102:14S-18S.
2. Barker JN: The immunopathology in psoriasis. Baillières Clin Rheumatol 1994;8:429-439.
3. Teranishi Y, Mizutani H, Murata M, Shimizu M, Matsushima K: Increased spontaneous production of IL-8 in peripheral blood monocytes from the psoriatic patient: Relation to focal infection and response to treatments. J Dermatol Sci 1995;10: 8-15.
4. Christophers E: The Immunopathology of Psoriasis. Int Arch Allergy Immunol 1996;110:199-206.
5. Gilhar A, Grossman N, Kahanovicz S, Reuveni H, Cohen S, Eitan A: Antiproliferative effect of pentoxifylline on psoriatic and normal epidermis: In vitro and in vivo studies. Acta Derm Venereol (Stockh) 1996; 76:437-441.
6. Ortonne JP: Aetiology and pathogenesis of psoriasis. Br J Dermatol 1996;135(suppl49):1-5.
7. Michel G, Gailis A, Jarzebska-Deussen B, Muschen A, Mirmohammadsadegh A, Ruzicka T: 1,25-(OH)2-vitamin D3 and calcipotriol induce IL-10 receptor gene expression in human epidermal cells. Inflamm Res 1997;46:32-34.
8. O'Donoghue MN, Melcher RE: Methotrexate for psoriasis revisited. Am Fam Physician 1997;19:99-102.
9. Barrera P, Haagsma CJ, Boerbooms AM, Van Riel PL, Borm GF, Van de Putte LB, Van der Meer JW: Effect of methotrexate alone or in combination with sulphasalazine on the production and circulating concentrations of cytokines and their antagonists. Longitudinal evaluation in patients with rheumatoid arthritis. Br J Rheumatol 1995;34:747-755.
10. Boffa MJ, Chalmers RJ: Methotrexate for psoriasis. Clin Exp Dermatol 1996;21:399-408.
11. Cuellar ML, Espinoza LR: Psoriatic arthritis. Current developments. J Fla Med Assoc 1995;82:338-347.
12. Morse RM, Perry HO, Hurt RD: Alcohol consumption and psoriasis. Dermatologica 1986;173:57-60.
13. Gupta MA, Schork NJ, Gupta AK, Ellis CN: Alcohol intake and treatment responsiveness of psoriasis: A prospective study. J Am Acad Dermatol 1993;28:730-732.
14. Higgins EM, du Vivier AWP: Cutaneous disease and alcohol misuse. Br Med Bull 1994;50:85-98.
15. Naldi L, Parazzini F, Brevi A, Peserico A, Veller Fornasa C, Grosso G, Rossi E, Marinaro P, Polenghi MM, Finzi A: Family history, smoking habits, alcohol consumption and risk of psoriasis. Br J Dermatol 1992;127:212-217.
16. Marrakchi S, Kim I, Delaporte E, Briand G, Degand P, Maibach HI, Thomas P: Vitamin A and E blood levels in erythrodermic and pustular psoriasis associated with chronic alcoholism. Acta Derm Venereol (Stockh) 1994;74:298-301.
17. Poikolainen KRT, Karvonen J: Smoking, alcohol and life events related to psoriasis among women. Br J Dermatol 1994;130:473-477.
18. McClain CJ, Cohen DA: Increased tumor necrosis factor production by monocytes in alcoholic hepatitis. Hepatology 1989;9:349-351.
19. Devière J, Content J, Denys C, Vandenbussche P, Schandene L, Wybran J, Dupont E: Excessive in vitro bacterial lipopolysaccharide-induced production of monokines in cirrhosis. Hepatology 1990;11:628-634.
20. Mozzanica N: Production of type-1 and type-2 cytokines by peripheral blood mononuclear cells of psoriatic patients. Immunology 1995;86: 422-426.
21. Mizutani H, Ohmoto Y, Mizutani T, Murata M, Shimizu M: Role of increased production of monocytes TNF-alpha, IL-1beta and IL-6 in psoriasis: Relation to focal infection, disease activity and responses to treatments. J Dermatol Sci 1997; 14:145-153.
22. Bonifati C, Trento E, Cordiali-Fei P, Carducci M, Mussi A, D'Auria L, Pimpinelli F, Fazio M, Ameglio F: Increased interleukin-6 concentrations in lesional skin and in the sera of patients with plaque-type psoriasis. Clin Immunol Immunopathol 1997;83:41-44.
23. Simpson RJ, Hammacher A, Smith DK, Matthews JM, Ward LD: Interleukin-6: structure-function relationships. Protein Sci 1997;6:929-955.
24. Ockenfels HM, Keim-Maas C, Funk R, Nussbaum G, Goos M: Ethanol enhances the IFN-gamma, TGF-alpha and IL-6 secretion in psoriatic co-cultures. Br J Dermatol 1996; 135:746-751.
25. Naume B, Shalaby R, Lesslauer W, Espevik T: Involvement of the 55- and 75-kDa tumor necrosis factor receptors in the generation of lymphokine-activated killer cell activity and proliferation of natural killer cells. J Immunol 1991;146:3045-3058.
26. Debets R: Expression of cytokines and their receptors by psoriatic fibroblasts. II. Decreased TNF receptor expression. Cytokine 1996b;8: 80-88.
27. Gilhar A, David M, Kalish RS, Weisinger AG: In vivo effects of cytokines on psoriatic skin grafted upon nude mice: Involvement of the tumor necrosis factor (TNF) receptor. Clin Exp Immunol 1996;106:134-142.
28. Yoshinaga Y: Detection of inflammatory cytokines in psoriatic skin. Arch Dermatol Res 1995;287:158-164.
29. Shear NH, Malkiewicz I, Klein D, Koren G, Randor S, Neuman MG: Acetaminophen-induced toxicity to keratinocytes and to hepatocytes in vitro is diminished by silymarin. Skin Pharmacol 1995;8:45-56.
30. Mosmann TR: Rapid colorimetric assay for cellular growth and survival. Application to proliferation and cytotoxicity assays. J Immunol Methods 1983;65:55-63.
31. Neuman MG, Shear NH, Bellentani S, Tiribelli C: Role of cytokines in ethanol-induced cytotoxicity in vitro Hep G2 cells. Gastroenterology 1998;115:157-166.
32. Jean NC: Direct blood injection method for gas Chromatographic determination of alcohols and other volatile compounds. Clin Chem 1971;17:82-85.
33. Buttke TM, McCubrey JA, Owen TC: Use of an aqueous tetrazolium/formazan assay to measure viability and proliferation of lymphokine dependent cell lines. J Immunol Methods 1993;15:233-240.
34. Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidimum thiochyanatephenol-chloroform extraction. Anal Biochem 1987;162:156-159.
35. Kawasaki ES: Amplification of RNA; in Innis MA, Gelfand DH, Sninsky JJ, White TJ (eds): PCR Protocols: A Guide to Methods and Applications. San Diego, Academic Press, 1989.
36. Tietze F: Enzymatic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Application to mammalian blood and other tissues. Anal Biochem 1969;27:502-522.
37. De Pita O, Ruffelli M, Cadoni S, Frezzolini A, Biava GF, Simom R, Bottari V, De Sanctis G: Psoriasis: Comparison of immunological markers in patients with acute and remission phase. J Dermatol Sci 1996;13:118-124.
38. Nickoloff BJ, Griffith CEM, Barker JNWN: The role of adhesion molecules chemotactic factors and cytokines in inflammatory and neoplastic skin disease - 1990 update. J Invest Dermatol 1990;94:1515-1575.
39. Kupper TS: Mechanism of cutaneous inflammation. Interaction between epidermal, cytokines, adhesion molecules and leukocytes. Arch Dermatol 1989;125:406-412.
40. Felver ME, Mezey E, McGuire M, Mitchell MC, Herlong HF, Veech GA, Veech RL: Plasma tumor necrosis factor alpha predicts decreased long-term survival in severe alcoholic hepatitis. Alcohol Clin Exp Res 1990;14:255-259.
41. Kaplowitz N, Tsukamoto H: Oxidative stress and liver disease. Prog Liver Dis 1996;14:131-139.
42. Garcia-Ruiz C, Colell A, Morales A, Kaplowitz N, Fernandez-Checa JC: Role of oxidative stress generated from the mitochondrial electron transport chain and mitochondrial glutathione status in loss of mitochondrial function and activation of transcription factor nuclear factor-kappa B: Studies with isolated mitochondria and rat hepatocytes. Mol Pharmacol 1995;48:825-834.