Ethanol enhances the IFN-γ, TGF-α and IL-6 secretion in psoriatic co-cultures

British Journal of Dermatology

Volumn 135, Issue 5, 1996, Pages 746-751

  Ockenfels, H M ^a   Keim Maas, C ^a   Funk, R ^a   Nussbaum G ^a   Goos, M ^a  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 6; INTERLEUKIN 8; TRANSFORMING GROWTH FACTOR ALPHA;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PSORIASIS;

EID: 0029906870     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2133.1996.tb03884.x     Document Type: Article

References (34)

1. Delaney TJ, Leppard B. Alcohol intake and psoriasis. Acta Derm Venereol (Stockh) 1974; 54: 237-8.
2. Kavli G, Forde OH, Arnesen E, Stenvold SE. Psoriasis: familial predisposition and environmental factors. Br Med J 1985; 291: 999-1000.
3. Carmichael MM, Stankler L, White MI. Alcohol intake of patients with psoriasis and dermatitis. Health Bull 1984; 42: 258-62.
4. Grunnert A. Alcohol consumption in psoriasis. Dermatologica 1974; 149: 136-9.
5. Vincenti GE, Blunden SM. Psoriasis and alcohol abuse. J R Army Med Corps 1987; 133: 77-8.
6. Morse RM, Perry HO, Hurt RD. Alcohol consumption and psoriasis. Dermatologica 1986; 173: 57-60.
7. Zanetti G, Peserico A, Groso G et al. Enhanced prevalence of red blood cell macrocytosis in psoriatic patients. A sign of ethanol abuse? Acta Derm Venereol (Stockh) 1989; 146 (Suppl.): 196-8.
8. Pokolainen KM, Reunala T, Karvonen J et al. Alcohol intake: a risk factor for psoriasis in young and middle aged men? Br Med J 1990; 300: 780-3.
9. Gupta MA, Schork NJ, Gupta AK, Ellis CN. Alcohol intake and treatment responsiveness of psoriasis: a prospective study. J Am Acad Dermatol 1993; 28: 730-2.
10. Marbet UA, Stalder GA, Vogt P, Bianchi L. Cellular immunoreactivity in chronic alcoholics with and without liver disease. Schweiz Med Wochenschr 1987; 117: 1901-94.
11. Mutchnick MG, Lee HH. Impaired lymphocyte proliferative response to mitogen in alcoholic patients. Absence of a relation to liver disease activity. Alcohol Clin Exp Res 1988; 12: 155-8.
12. Schopf RE, Trompeter M, Bork K, Morsches B. Effects of ethanol and acetaldehyde on phagocytic functions. Arch Dermatal Res 1985; 277: 131-7.
13. Ockenfels HM, Morsches B, Schopf RE. Chloroquine, ethanol and indomethacin affect lymphocyte proliferation in patients with psoriasis. J Invest Dermatol 1993; 100: 216 (Abstr.).
14. Baker S, Fry L. The immunology of psoriasis. Br J Dermatol 1991; 126: 1-9.
15. Barker JNWN. The pathophysiology of psoriasis. Lancet 1991; 338: 227-30.
16. Uyemura K, Yamamura M, Fivenson DF et al. The cytokine network in lesional and lesion-free psoriatic skin is characterized by a T-helper type 1 cell-mediated response. J Invest Dermatol 1993; 101: 701-5.
17. Kemény L, Michel G, Bobozy A, Runicka T. Cytokine system as potential target for antipsoriatic therapy. Exp Dermatol 1994; 3: 1-8.
18. Delaporte E, Bieber T, Viac J, et al. Cytokine épidermiques et inflammation cutanée. Ann Dermatol Venereol 1994; 121: 836-43.
19. Gearing AJH, Fincham NJ, Bird CR et al. Cytokines in skin lesions of psoriasis. Cytokine 1990; 2: 68-75.
20. Stoof TJ, Mitra RS, Sarma V, Dixit VM et al. Keratinocyte activation following T lymphocyte binding. J Invest Dermatol 1992; 98: 92-5.
21. Ockenfels HM, Wagner SN, Keim-Maas C et al. Lithium and psoriasis: cytokine modulation of cultured lymphocytes and psoriatic keratinocytes. Arch Dermatol Res 1996; 288: 173-8.
22. Elder JT, Fisher GJ, Lindquist PB. Overexpression of transforming growth factor alpha in psoriatic epidermis. Science 1989; 242: 811-14.
23. Janula J, Novotny F. Zur statistischen Erforschung der Psoriasis. Hautarzt 1965; 16: 241-6.
24. Nickoloff BJ, Mitra RS, Elder JT et al. Decreased growth inhibition by recombinant gamma interferon is associated with increased transforming growth factor-alpha production in keratinocytes cultured from psoriatic lesions. Br J Dermatol 1989; 121: 161-74.
25. Powrie F, Coffman RL. Cytokine regulation of T-cell function: potential for therapeutic intervention. Immunol Today 1993; 14: 270-4.
26. Finzi E, Harkins R, Horn T. TGF-α is widely expressed in differentiated as well as hyperproliferative skin epithelium. J Invest Dermatol 1991; 96: 328-32.
27. Ansel J, Perry P, Brown J et al. Cytokine modulation of keratinocyte cytokines. J Invest Dermatol 1990; 94: 101-7S.
28. Wang Y, Huang DS, Gigger PT, Watson RR. Influence of chronic dietary ethanol on cytokine production by murine splenocytes and thymocytes. Alcohol Clin Exp Res 1994; 18: 64-70.
29. Brodle C, Domenico J, Gelfand EW. Ethanol inhibits early events in T-lymphocyte activation. Clin Immunol Immunopathol 1994; 70: 129-36.
30. Sheron N, Ceska M, Lindley I, Williams R. Ethanol suppresses in vitro interleukin-8 synthesis production in Hep-G2 cells. J Hepatol 1992; 16 (Suppl. 1): S61.
31. Stafnini GF, Mazzetti M, Zunarelli P et al. In vivo effects of chronic alcohol abuse on membrane α1-glycoprotein of lymphocytes and immune response to various stimulating agents. Alcohol Clin Exp Res 1989; 13: 444-8.
32. Roselle GA, Mendenhall CL, Grossman CJ. Age dependent alterations of host immune response in the ethanol-fed rat. J Clin Lab Immunol 1989; 29: 99-103.
33. Razani-Boroujerdi S, Savage SM, Sopori ML. Alcohol-induced changes in the immune response: immunological effects of chronic ethanol intake are genetically regulated. Toxicol Appl Pharmacol 1994; 127: 37-43.
34. Schopf RE, Ockenfels HM, Morsches B. Ethanol enhances the mitogen-driven lymphocyte proliferation in patients with psoriasis. Acta Derm Venereol (Stockh) 1996; 76: 260-3.