Synthesis and in vivo studies of [C-11]N-methylepibatidine: Comparison of the stereoisomers

Nuclear Medicine and Biology

Volumn 26, Issue 2, 1999, Pages 165-173

  Patt, Jörg T ^a   Spang, Jörg E ^b   Westera, Gerrit ^a   Buck, Alfred ^a   Schubiger, P August ^b  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b ETH ZURICH   (Switzerland)

Author keywords

Biodistribution; N methyl epibatidine; Nicotinic receptor; Positron emission tomography

Indexed keywords

EPIBATIDINE; METHYLEPIBATIDINE; NICOTINIC RECEPTOR; TRACER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DESENSITIZATION; DRUG SYNTHESIS; IN VIVO STUDY; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PROTON NUCLEAR MAGNETIC RESONANCE; RECEPTOR AFFINITY; RECEPTOR BINDING; STEREOISOMERISM; TISSUE DISTRIBUTION;

ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; BRAIN; CARBON RADIOISOTOPES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; MALE; MICE; MICE, INBRED ICR; NICOTINIC AGONISTS; PYRIDINES; RATS; STEREOISOMERISM; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED; TOXICITY TESTS;

EID: 0033023885     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8051(98)00084-5     Document Type: Article

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