Enzymatic and functional correction along with long-term enzyme secretion from transduced bone marrow hematopoietic stem/progenitor and stromal cells derived from patients with fabry disease

Experimental Hematology

Volumn 27, Issue 7, 1999, Pages 1149-1159

  Takenaka, Toshihiro ^a   Hendrickson, Chad S ^a   Tworek, David M ^a   Tudor, Matthew ^a   Schiffmann, Raphael ^a   Brady, Roscoe O ^a   Medin, Jeffrey A ^b  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

CD34+ cells; Fabry disease; Long term bone marrow culture; Retroviral gene transfer

Indexed keywords

ALPHA GALACTOSIDASE; CD34 ANTIGEN; HYDROLASE;

ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; ENZYME DEFICIENCY; ENZYME RELEASE; FABRY DISEASE; FIBROBLAST; GENE TRANSFER; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; LIPID STORAGE; LYMPHOBLAST; LYSOSOME STORAGE DISEASE; PRIORITY JOURNAL; STROMA CELL; TARGET CELL;

ALPHA-GALACTOSIDASE; ANIMALS; BONE MARROW CELLS; CELL ADHESION; CELLS, CULTURED; DNA, VIRAL; FABRY DISEASE; GENE THERAPY; GENETIC VECTORS; GLYCOSPHINGOLIPIDS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HUMANS; LYSOSOMES; MICE; PROVIRUSES; RETROVIRIDAE; STROMAL CELLS; TRANSFECTION;

EID: 0033019187     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-472X(99)00050-8     Document Type: Article

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