Synthesis and membrane permeability of PNA-peptide conjugates

Bioorganic and Medicinal Chemistry Letters

Volumn 7, Issue 23, 1997, Pages 3001-3006

  Simmons, Carla G ^a   Pitts, Anne E ^a   Mayfield, Lynn D ^a   Shay, Jerry W ^b   Corey, David R ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; PEPTIDE; PEPTIDE NUCLEIC ACID;

ARTICLE; CELL LINE; CONTROLLED STUDY; DERIVATIZATION; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG PURIFICATION; DRUG SYNTHESIS; DRUG UPTAKE; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; MASS SPECTROMETRY; MEMBRANE PERMEABILITY; TUMOR CELL;

EID: 0030723924     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(97)10136-6     Document Type: Article

References (19)

1. Nielsen, P. E.; Egholm, M.; Berg, R. H.; Buchardt, O. Science 1991, 254, 1497.
2. Egholm, M.; Buchardt, O.; Christensen, L.; Behrens, C.; Freier, S. M.; Driver, D. A.; Berg, R. H.; Kim, S. K.; Nordern, B.; Neilsen, P. E. Nature (London) 1993, 365, 566.
3. Smulevitch, S. V.; Simmons, C. G.; Norton, J. C.; Wise, T. W.; Corey, D. R. Nat. Biotech. 1996, 14, 1700.
4. Demidov, V.; Potaman, V. N.; Frank-Kamenetskii, M. D.; Buchardt, O.; Nielsen, P. E. Biochem. Pharmacol. 1994, 48, 1310.
5. Hamilton, S. E.; Iyer, M.; Norton, J. C.; Corey, D. R. Bioorg. Med. Chem. Lett. 1996, 6, 2897.
6. Corey, D. R. Trends in Biotechnology 1997, 15, 224.
7. Landsdorp, P. M.; Verwoerd, N. P.; van de Rijke, F. M.; Dragowska, V.; Little, M-T.; Dirks, R. W.; Raap, A. K.; Tanke, H. J. Hum. Mol. Genet. 1996, 5, 685.
8. Boffa, L. C.; Morris, P. L.; Carpaneto, E. M.; Louissaint, M.; Allfrey, V. G. J. Biol. Chem. 1996, 271, 13228.
9. Carlsson, C.; Jonsson, M.; Norden, B.; Dulay, M. T.; Zare, R. N.; Noolandl, J.; Nielsen, P. E.; Tsui, L-C.; Zielenski, J. Nature (London) 1996, 380, 207.
10. Perry-O'Keefe, H.; Yao, X-W.; Coull, J. M.; Fuchs, M.; Egholm, M. Proc. Natl. Acad. Sci. U.S.A. 1996, 93, 14670.
11. Norton, J. C.; Piatyszek, M. A.; Wright, W. E.; Shay, J. W.; Corey, D. R. Nature Biotech. 1996, 14, 615.
12. Wittung, P.; Kajanus, J.; Edwards, K.; Nielsen, P.; Norden, B.; Malmstrom, B. FEBS Lett. 1995, 365, 27.
13. Bonham, M. A.; Brown, S.; Boyd, A. L; Brown, P. H.; Bruckenstein, D. A.; Hanvey, J. C.; Thomson, S. A.; Pipe, A.; Hassman, F.; Bisi, J. E.; Froehler, B. C.; Matteucci, M. D.; Wagner, R. W.; Noble, S. A.; Babiss, L. E. Nucleic Acids. Res. 1995, 23, 3003.
14. Uhlmann, E.; Will, D. W.; Breipohl, G.; Langner, D.; Ryte, A. Angew. Chem. Int. Ed. Engl. 1996, 35, 2632.
15. Basu, S.; Wickstrom, E. Bioconjugate Chem. 1997, 8, 481.
16. Lin, Y-Z.; Yao, S.; Veach, R. A.; Torgerson, T. R.; Hawiger, J. J. Biol. Chem. 1995, 24, 14255.
17. Prochaintz, A. Curr. Op. Neurobiology 1996, 8, 629.
18. Fawell, S.; Seery, J.; Daikh, Y.; Moore, C.; Chen, L. L.; Pepinsky, B.; Barsoum, J. Proc. Natl. Acad. U.S.A. 1994, 91, 664.
19. Norton, J. C.; Waggenspack, J. H.; Varnum, E.; Corey, D. R. Bioorg. Med. Chem. 1995, 3, 437.