Specificity of mutations induced by methyl methanesulfonate in mismatch repair-deficient human cancer cell lines

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 427, Issue 2, 1999, Pages 67-78

  Glaab, Warren E ^a   Tindall, Kenneth R ^b   Skopek, Thomas R ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

HPRT; Methyl methanesulfonate; Mismatch repair; Mutational specificity

Indexed keywords

MESYLIC ACID METHYL ESTER;

ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DNA REPAIR; EXCISION REPAIR; FRAMESHIFT MUTATION; GENE MUTATION; HUMAN; HUMAN CELL; MUTAGENESIS; MUTAGENICITY; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, ALKYLATING; BASE PAIR MISMATCH; DNA REPAIR; GUANINE; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; METHYL METHANESULFONATE; MUTAGENS; MUTATION; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; RNA, MESSENGER; SEQUENCE ANALYSIS; TUMOR CELLS, CULTURED;

EID: 0033006456     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(99)00091-3     Document Type: Article

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