Working towards a Helicobacter pylori vaccine

Gastroenterology

Volumn 116, Issue 4, 1999, Pages 990-994

  Czinn, S J ^a   Nedrud, J G ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL INFECTION; CANCER RISK; EDITORIAL; HELICOBACTER PYLORI; IMMUNIZATION; INFECTION CONTROL; PEPTIC ULCER; PRIORITY JOURNAL; VACCINE PRODUCTION;

EID: 0032999061     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0016-5085(99)70084-3     Document Type: Editorial

References (34)

1. JR Warren BJ Marshall Unidentified curved bacilli on gastric epithelium in active chronic gastritis Lancet 1 1983 1273 1275
2. SJ Czinn A Cai JG Nedrud Protection of germ-free mice from infection by Helicobacter felis after active oral or passive IgA immunization Vaccine 11 1993 637 642
3. M Chen A Lee S Hazell P Hu Y Li Immunisation against gastric infection with Helicobacter species: first step in the prophylaxis of gastric cancer? Zentrabl Bakteriol 280 1993 155 165
4. TG Blanchard SJ Czinn JG Nedrud Host response and vaccine development TU Westblom SJ Czinn JG Nedrud Gastroduodenal disease and Helicobacter pylori Volume 241 1999 Springer Verlag Berlin 181 213
5. C Doidge I Gust A Lee F Buck S Hazell U Manne Therapeutic immunization against Helicobacter infection (letter) Lancet 343 1994 913 914
6. I Corthesy-Theulaz N Porta M Glauser E Saraga A-C Vaney R Haas JP Kraehenbuhl AL Blum P Michetti Oral immunization with Helicobacter pylori urease B subunit as a treatment against Helicobacter infection in mice Gastroenterology 109 1995 115 121
7. R Cuenca TG Blanchard SJ Czinn JG Nedrud TP Monath CK Lee RW Redline Therapeutic immunization against Helicobacter mustelae infection in naturally infected ferrets Gastroenterology 110 1996 1770 1775
8. P Ghiara M Rossi M Marchetti A Di Tommaso C Vindigni F Ciampolini A Covacci JL Telford MT De Magistris M Pizza R Rappuoli G Del Giudice Therapeutic intragastric vaccination against Helicobacter pylori in mice eradicates an otherwise chronic infection and confers protection against reinfection Infect Immun 65 1997 4996 5002
9. P Michetti C Kreiss KL Kotloff N Porta J-L Blanco D Bachmann M Herranz PF Saldinger I Corthésy-Theulaz G Losonsky R Nichols J Simon M Stolte S Ackerman TP Monath AL Blum Oral immunization with urease and Escherichia coli heat-labile enterotoxin is safe and immunogenic in Helicobacter pylori– infected adults Gastroenterology 116 1999 804 812
10. C Kreiss T Buclin M Cosma I Corthesy-Theulaz P Michetti Safety of oral immunisation with recombinant urease in patients with Helicobacter pylori infection (letter) Lancet 347 1996 1630 1631
11. RL Ferrero J-M Thiberge I Kansau N Wuscher M Huerre A Labigne The groES homolog of Helicobacter pylori confers protective immunity against mucosal infection in mice Proc Natl Acad Sci USA 92 1995 6499 6503
12. M Marchetti B Arico D Burroni N Figura R Rappuoli P Ghiara Development of a mouse model of Helicobacter pylori infection that mimics human disease Science 267 1995 1655 1658
13. TG Blanchard SJ Czinn R Maurer WD Thomas G Soman JG Nedrud Urease-specific monoclonal antibodies prevent Helicobacter felis infection in mice Infect Immun 63 1995 1394 1399
14. TH Ermak PJ Giannasca R Nichols GA Myers J Nedrud R Weltzin CK Lee H Kleanthous TP Monath Immunization of mice with urease vaccine affords protection against Helicobacter pylori infection in the absence of antibodies and is mediated by MHC class II–restricted responses J Exp Med 188 1998 2277 2288
15. TG Blanchard SJ Czinn RW Redline N Sigmund G Harriman JG Nedrud Antibody-independent protective mucosal immunity to gastric Helicobacter infection in mice Cell Immunol 191 1999 74 80
16. P Sutton J Wilson T Koska A Lee Helicobacter pylori immunisation: a therapeutic effect without antibodies Gut 43 suppl 1998 A37
17. M Mohammadi J Nedrud R Redline N Lycke S Czinn Murine CD4 T cell responses to Helicobacter infection: TH1 cells enhance gastritis and TH2 cells reduce bacterial load Gastroenterology 113 1997 1848 1857
18. PF Saldinger N Porta P Launois JA Louis GA Waanders H Bouzourene P Michetti AL Blum IE Corthesy-Theulaz Immunization of BALB/c mice with Helicobacter urease B induces a T helper 2 response absent in Helicobacter infection Gastroenterology 115 1998 891 897
19. J Pappo D Torrey L Castriotta A Savinainen Z Kabok A Ibraghimov Helicobacter pylori infection in immunized mice lacking major histocompatibility complex class I and class II functions Infect Immun 67 1999 337 341
20. WJ Cieplak DJ Mead RJ Messer CCR Grant Site-directed mutagenic alteration of potential active-site residues of the A subunit of Escherichia coli heat-labile enterotoxin J Biol Chem 270 1995 30545 30550
21. BL Dickinson JD Clements Dissociation of Escherichia coli heat-labile enterotoxin adjuvanticity from ADP-ribosyltransferase activity Infect Immun 63 1995 1617 1623
22. S Yamamoto H Kiyono M Yamamoto K Imaoka K Fujihashi FW Van Ginkel M Noda Y Takeda JR McGhee A nontoxic mutant of cholera toxin elicits Th2-type responses for enhanced mucosal immunity Proc Natl Acad Sci USA 94 1997 5267 5272
23. M Marchetti M Rossi V Giannelli MM Giuliani M Pizza S Censini A Covacci P Massari C Pagliaccia R Manetti JL Telford G Douce G Dougan R Rappuoli P Ghiara Protection against Helicobacter pylori infection in mice by intragastric vaccination with H. pylori antigens is achieved using a non-toxic mutant of E. coli heat-labile enterotoxin (LT) as adjuvant Vaccine 16 1998 33 37
24. K Komase S Tamura K Matsuo K Watanabe N Hattori A Odaka Y Suzuki T Kurata C Aizawa Mutants of Escherichia coli heat-labile enterotoxin as an adjuvant for nasal influenza vaccine Vaccine 16 1998 248 254
25. G Hajishengallis SM Michalek MW Russell Persistence of serum and salivary antibody responses after oral immunization with a bacterial protein antigen genetically linked to the A2/B subunits of cholera toxin Infect Immun 64 1996 665 677
26. A Lee M Chen Successful immunization against gastric infection with Helicobacter species: use of a cholera toxin B-subunit-whole-cell vaccine Infect Immun 62 1994 3594 3597
27. TG Blanchard N Lycke SJ Czinn JG Nedrud Recombinant cholera toxin B subunit is not an effective mucosal adjuvant for oral immunization of mice against H. felis Immunology 94 1998 22 27
28. HY Wu MW Russell Induction of mucosal and systemic immune responses by intranasal immunization using recombinant cholera toxin B subunit as an adjuvant Vaccine 16 1998 286 292
29. LC Ågren L Ekman B Löwenadler NY Lycke Genetically engineered nontoxic vaccine adjuvant that combines B cell targeting with immunomodulation by cholera toxin A1 subunit J Immunol 158 1997 3936 3946
30. LC Ågren L Ekman B Löwenadler JG Nedrud NY Lycke Adjuvanticity of the cholera toxin A1-based gene fusion protein, CTA1-DD, is critically dependent on the ADP-ribosylatransferase and Igbinding activity J Immunol 162 1999 2432 2440
31. B Guy C Hessler S Fourage J Haensler E Vialon-Lafay B Rokbi M-JQ Millet Systemic immunization with urease protects mice against Helicobacter pylori infection Vaccine 16 1998 850 856
32. A Lee Therapeutic immunization against Helicobacter infection (editorial) Gastroenterology 110 1996 2003 2006
33. P Michetti I Corthesy-Thelaz C Davin R Haas A-C Vaney M Heitz J Bille JP Kraehenbuhl E Saraga AL Blum Immunization of Balb/c mice against Helicobacter felis infection with Helicobacter pylori urease Gastroenterology 107 1994 1002 1011
34. M Mohammadi S Czinn R Redline J Nedrud Helicobacter -specific cell-mediated immune responses display a predominant TH1 phenotype and promote a DTH response in the stomachs of mice J Immunol 156 1996 4729 4738