A human population bottleneck can account for the discordance between patterns of mitochondrial versus nuclear DNA variation [1]

Molecular Biology and Evolution

Volumn 16, Issue 7, 1999, Pages 1003-1005

  Fay, Justin C ^a   Wu, Chung I ^b  

^a Cancer Biology and Developmental Biology   (United States)

^b NONE

Author keywords

Homo sapiens; Human evolution; Population bottleneck

Indexed keywords

CELL NUCLEUS DNA; MITOCHONDRIAL DNA;

GENE FREQUENCY; GENE MUTATION; GENOME; LETTER; MUTATION RATE;

HOMO SAPIENS;

EID: 0032970601     PISSN: 07374038     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.molbev.a026175     Document Type: Letter

References (18)

1. CLARK, A. G., K. M. WEISS, D. A. NICKERSON et al. (11 co-authors). 1998. Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase. Am. J. Hum. Genet. 63:595-612.
2. FU, Y. X. 1996. New statistical tests of neutrality for DNA samples from a population. Genetics 143:557-570.
3. FU, Y. X., and W. H. LI. 1993. Statistical tests of neutrality of mutations. Genetics 133:693-709.
4. HARDING, R. M., S. M. FULLERTON, R. C. GRIFFITHS, J. BOND, M. J. COX, J. A. SCHNEIDER, D. S. MOULIN, and J. B. CLEGG. 1997. Archaic African and Asian lineages in the genetic ancestry of modern humans. Am. J. Hum. Genet. 60:772-789.
5. HEY, J. 1997. Mitochondrial and nuclear genes present conflicting portraits of human origins. Mol. Biol. Evol. 14:166-172.
6. HORAI, S., K. HAYASAKA, R. KONDO, K. TSUGANE, and N. TAKAHATA. 1995. Recent African origin of modern humans revealed by complete sequences of hominoid mitochondrial DNAs. PNAS 92:532-536.
7. KIMMEL, M., R. CHAKRABORTY, J. P. KING, M. BAMSHAD, W. S. WATKINS, and L. B JORDE. 1998. Signatures of population expansion in microsatellite repeat data. Genetics 148: 1921-1930.
8. MERRIWETHER, D. A., A. G. CLARK, S. W. BALLINGER, T. G. SCHURR, H. SOODYALL, T. JENKINS, S. T. SHERRY, and D. C. WALLACE. 1991. The structure of human mitochondrial DNA variation. J. Mol. Evol. 33:543-555.
9. NEI, M., T. MARUYAMA, and R. CHAKRABORTY. 1975. The bottleneck effect and genetic variability in populations. Evolution 29:1-10.
10. ROGERS, A. R., and H. HARPENDING. 1992. Population growth makes waves in the distribution of pairwise genetic differences. Mol. Biol. Evol. 9:552-569.
11. SIMONSEN, K. L., G. A. CHURCHILL, and C. F. AQUADRO. 1995. Properties of statistical tests of neutrality for DNA polymorphism data. Genetics 141:413-429.
12. STRINGER, C. B., and P. ANDREWS. 1988. Genetic and fossil evidence for the origin of modern humans. Science 239: 1263-1268.
13. TAJIMA, F. 1989a. Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. Genetics 123: 585-595.
14. _. 1989b. The effect of change in population size on DNA polymorphism. Genetics 123:597-601.
15. TAKAHATA, N., and Y. SATTA. 1997. Evolution of the primate lineage leading to modern humans: phylogenetic and demographic inferences from DNA sequences. PNAS 94: 4811-4815.
16. TEMPLETON, A. R. 1997. Out of Africa? What do genes tell us? Curr. Opin. Genet. Dev. 7:841-847.
17. WATTERSON, G. A. 1975. On the number of segregating sites in genetic models without recombination. Theor. Popul. Biol. 7:256-276.
18. ZIETKIEWICZ, E., V. YOTOVA, M. JARNIK et al. (11 co-authors). 1998. Genetic structure of the ancestral population of modern humans. J. Mol. Evol. 47:146-155.