Calcitonin-dependent down-regulation of the mouse C1a calcitonin receptor in cells of the osteoclast lineage involves a transcriptional mechanism

Endocrinology

Volumn 140, Issue 3, 1999, Pages 1060-1068

  Inoue, Daisuke ^a,e   Shih, Chung ^b   Galson, Deborah L ^c   Goldring, Steven R ^c   Horne, William C ^b   Baron, Roland ^a,d  

^a YALE CANCER CENTER   (United States)

^b NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^c HARVARD MEDICAL SCHOOL   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BUCLADESINE; CALCITONIN; CALCITONIN RECEPTOR; FORSKOLIN; MESSENGER RNA;

ANIMAL CELL; ARTICLE; DOWN REGULATION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; MALE; MOUSE; NEWBORN; NONHUMAN; OSTEOCLAST; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RIBONUCLEASE PROTECTION ASSAY; TRANSCRIPTION REGULATION;

EID: 0032956906     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.140.3.6551     Document Type: Article

References (49)

1. 1. Copp DH 1969 Calcitonin and parathyroid hormone. Annu Rev Pharmacol 9:327-344
2. 2 Nicholson GC, Moseley JM, Sexton PM, Mendelsohn FAO, Martin TJ 1986 Abundant calcitonin receptors in isolated rat osteoclasts: biochemical and autoradiographic characterization. J Clin Invest 78:355-360
3. 3. Azria M, Copp DH, Zanelli JM 1995 25 years of salmon calcitonin: from synthesis to therapeutic use. Calcif Tissue Int 57:405-408
4. 4. Wener JA, Gorton SJ, Raisz LG 1972 Escape from inhibition of resorption in cultures of fetal bone treated with calcitonin and parathyroid hromone. Endocrinology 90:752-759
5. 5. Silva OL, Becker KL 1973 Salmon calcitonin in the treatment of hypercalcemia. Arch Intern Med 132:337-339
6. 6. Binstock ML, Mundy GR 1980 Effect of calcitonin and glutocorticoids in combination on the hypercalcemia of malignancy. Ann Intern Med 93:269-272
7. 7. Lin HY, Harris TL, Flannery MS, Aruffo A, Kaji EH, Gorn A, Kolakowski LF, Lodish HF, Goldring SR 1991 Expression cloning of an adenylate cyclase-coupled calcitonin receptor. Science 254:1022-1024
8. 8. Gorn AH, Lin HY, Yamin M, Auron PE, Flannery MR, Tapp DR, Manning CA, Lodish HF, Krane SM, Goldring SR 1992 Cloning, characterization, and expression of a human calcitonin receptor from an ovarian carcinoma cell line. J Clin Invest 90:1726-1735
9. 9. Sexton PM, Houssami S, Hilton JM, O'Keeffe LM, Center RJ, Gillespie MT, Darcy P, Findlay DM 1993 Identification of brain isoforms of the rat calcitonin receptor. Mol Endocrinol 7:815-821
10. 10. Yamin M, Gorn AH, Flannery MR, Jenkins NA, Gilbert DJ, Copeland NG, Tapp DR, Krane SM, Goldring SR 1994 Cloning and characterization of a mouse brain calcitonin receptor complementary deoxyribonucleic acid and mapping of the calcitonin receptor gene. Endocrinology 135:2635-2643
11. 11. Shyu JF, Inoue D, Baron R, Home WC 1996 The deletion of 14 amino acids in the seventh transmembrane domain of a naturally occurring calcitonin receptor isoform alters ligand binding and selectively abolishes coupling to phospholipase C. J Biol Chem 271:31127-31134
12. 12. Sarkar A, Dickerson IM 1997 Cloning, characterization, and expression of a calcitonin receptor from guinea pig brain. J Neurochem 69:455-464
13. 13. Segre GV, Goldring SR 1993 Receptors for secretin, calcitonin, parathyroid hormone (PTH)/PTH-related peptide, vasoactive intestinal peptide, glucagon-like peptide 1, growth hormone-releaing hormone, and glucagon belong to a newly discovered G-protein-linked receptor family. Trends Endocrinol Metab 4:309-314
14. 14. Kuestner RE, Elrod RD, Grant FJ, Hagen FS, Kuijper JL, Matthewes SL, O'Hara PJ, Sheppard PO, Stroop SD, Thompson DL, Whitmore TE, Findlay DM, Houssami S, Sexton PM, Moore EE 1994 Cloning and characterization of an abundant subtype of the human calcitonin receptor. Mol Pharmacol 46:246-255
15. 15. Albrandt K, Brady EMG, Moore CX, Mull E, Sierzega ME, Beaumont K 1995 Molecular cloning and functional expression of a third isoform of the human calcitonin receptor and partial characterization of the calcitonin receptor gene. Endocrinology 136:5377-5384
16. 16. Zolnierowicz S, Cron P, Solinas-Toldo S, Friess R, Lin HY, Hemmings BA 1994 Isolation, characterization, and chromosomal localization of the porcine calcitonin receptor gene. Identification of two variants of the receptor generated by alternative splicing. J Biol Chem 269:19530-19538
17. 17 Ikegame M, Rakopoulos M, Zhou H, Houssami S, Martin TJ, Moseley JM, Findlay DM 1995 Calcitonin receptor isoforms in mouse and rat osteoclasts. J Bone Miner Res 10:59-65
18. 18. Takahashi S, Goldring S, Katz M, Hilsenbeck S, Williams R, Roodman GD 1995 Downregulation of calcitonin receptor mRNA expression by calcitonin during human osteoclast-like cell differentiation. J Clin Invest 95:167-171
19. 19. Rakopoulos M, Ikegame M, Findlay DM, Martin TJ, Moseley JM 1995 Short treatment of osteoclasts in bone marrow culture with calcitonin causes prolonged suppression of calcitonin receptor mRNA. Bone 17:447-453
20. 20. Lee SK, Goldring SR, Lorenzo JA 1995 Expression of the calcitonin receptor in bone marrow cell cultures and in bone: a specific marker of the differentiated osteoclast that is regulated by calcitonin. Endocrinology 136:4572-4581
21. 21. Wada S, Udagawa N, Nagata N, Martin TJ, Findlay DM 1996 Calcitonin receptor down-regulation relates to calcitonin resistance in mature mouse osteoclasts. Endocrinology 137:1042-1048
22. 22. Wada S, Udagawa N, Akatsu T, Nagata N, Martin TJ, Findlay DM 1997 Regulation by calcitonin and glucocorticoids of calcitonin receptor gene expression in mouse osteoclasts. Endocrinology 138:521-529
23. 23. Ikegame M, Rakopoulos M, Martin TJ, Moseley JM, Findlay DM 1996 Effects of continuous calcitonin treatment on osteoclast-like cell development and calcitonin receptor expression in mouse bone marrow cultures. J Bone Miner Res 11:456-465
24. 24. Miyoshi I, Kubonishi I, Yoshimoto S, Akagi T, Ohtsuki Y, Shiraishi Y, Nagata K, Hinuma Y 1981 Type C virus particles in a cord T-cell line derived by co-cultivating normal human cord leukocytes and human leukaemic T cells. Nature 294:770-771
25. 25. Ruddle NH, Li C-B, Horne WC, Santiago P, Troiano N, Jay G, Horowitz M, Baron R 1993 Mice transgenic for HTLV-1 LTR-tax exhibit tax expression in bone, skeletal alterations, and high bone turnover. Virology 197:196-204
26. 26. Takahashi N, Akatsu T, Udagawa N, Sasaki T, Yamaguchi A, Moseley JM, Martin TJ, Suda T 1988 Osteoblastic cells are involved in osteoclast formation. Endocrinology 123:2600-2602
27. 27. Akatsu T, Tamura T, Takahashi N, Udagawa N, Tanaka S, Sasaki T, Yamaguchi A, Nagata N, Suda T 1992 Preparation and characterization of a mouse osteoclast-like multinucleated cell population. J Bone Miner Res 7:1297-1306
28. 28. Chomczynski P, Sacchi N 1987 Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159
29. 29. Nicholson GC, Moseley JM, Yates AJP, Martin TJ 1987 Control of cyclic adenosine 3′,5′-monophosphate production in osteoclasts: calcitonin-induced persistent activation and homologous desensitization of adenylate cyclase. Endocrinology 120:1902-1908
30. 30. Houssami S, Findlay DM, Brady CL, Myers DE, Martin TJ, Sexton PM 1994 Isoforms of the rat calcitonin receptor: consequences for ligand binding and signal transduction. Endocrinology 135:183-190
31. 2+/inositol phosphate signaling pathways. Mol Endocrinol 6:551-556
32. i, protein kinase C, and calcium. J Biol Chem 273:19809-19816
33. 33. Wada S, Udagawa N, Nagata N, Martin TJ, Findlay DM 1996 Physiological levels of calcitonin regulate the mouse osteoclast calcitonin receptor by a protein kinase A-mediated mechanism. Endocrinology 137:312-320
34. 34. Azria M 1989 The Calcitonins: Physiology, and Pharmacology, Karger, Basel, pp 1-152
35. 35. Wada S, Martin TJ, Findlay DM 1995 Homologous regulation of the calcitonin receptor in mouse osteoclast-like cells and human breast cancer T47D cells. Endocrinology 136:2611-2621
36. 36. McCarthy JEG, Kollmus H 1995 Cytoplasmic mRNA-protein interactions in eukaryotic gene expression. Trends Biochem Sci 20:191-197
37. 37. Yang M, Kurkinen M 1994 Different mechanisms of regulation of the human stromelysin and collagenase genes. Analysis by a reverse-transcription-coupled-PCR assay. Eur J Biochem 222:651-658
38. 38. Elferink CJ, Reinere JJ, Jr 1996 Quantitative RT-PCR on CYP1A1 heterogeneous nuclear RNA: a surrogate for the in vitro transcription run-on assay. BioTechniques 20:470-477
39. 39. Gabbitas B, Pash JM, Delany AM, Canalis E 1996 Cortisol inhibits the synthesis of insulin-like growth factor-binding protein-5 in bone cell cultures by transcriptional mechanisms. J Biol Chem 271:9033-9038
40. 40. Franchimont N, Rydziel S, Delany AM, Canalis E 1997 Interleukin-6 and its soluble receptor cause a marked induction of collagenase 3 expression in rat osteoblast cultures. J Biol Chem 272:12144-12150
41. 41. Sexton PM, Hilton JM 1992 Biologically active salmon calcitonin-like peptide is present in rat brain. Brain Res 596:279-284
42. 42. Lamp SJ, Findlay DM, Moseley JM, Martin TJ 1981 Calcitonin induction of a persistent activated state of adenylate cyclase in human breast cancer cells (T47D). J Biol Chem 256:12269-12274
43. 43. Sunahara RK, Dessauer CW, Gilman AG 1996 Complexity and diversity of mammalian adenylyl cyclases. Annu Rev Pharmacol Toxicol 36:461-480
44. 5-stimulated adenylyl cyclases. FASEB J 7:768-775
45. 45. Seamon KB, Daly JW 1986 Forskolin: its biological and chemical properties. Adv Cyclic Nucleotide Protein Phosphorylation Res 20:1-150
46. 46. Laurenza A, Sutkowski EM, Seamon KB 1989 Forskolin: a specific stimulator of adenylyl cyclase or a diterpene with multiple sites of action? Trends Pharmacol Sci 10:442-447
47. 47. Bentley DL, Groudine M 1986 A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells. Nature 321:702-706
48. 48. Plet A, Eick D, Blanchard JM 1995 Elongation and premature termination of transcripts initiated from c-fos and c-myc promoters show dissimilar patterns. Oncogene 10:319-328
49. 49. Bender TP, Thompson CB, Kuehl WM 1987 Differential expression of c-myb mRNA in murine B lymphomas by a block to transcription elongation. Science 237:1473-1476