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Volumn 29, Issue 2-3, 1999, Pages 250-264

An integrated view of pathophysiological models of schizophrenia

Author keywords

Amphetamine; Animal model; Dopamine; Ketamine; NMDA; Schizophrenia; Stress

Indexed keywords

AMPHETAMINE; DOPAMINE; KETAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

EID: 0032950134     PISSN: 01650173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0173(99)00002-8     Document Type: Review
Times cited : (137)

References (224)
  • 1
    • 0032103160 scopus 로고    scopus 로고
    • Effects of ketamine on thought disorder, working memory, and semantic memory in healthy volunteers
    • Adler C.M., Goldberg T.E., Malhotra A.K., Pickar D., Breier A. Effects of ketamine on thought disorder, working memory, and semantic memory in healthy volunteers. Biol. Psychiatry. 43:1998;811-816.
    • (1998) Biol. Psychiatry , vol.43 , pp. 811-816
    • Adler, C.M.1    Goldberg, T.E.2    Malhotra, A.K.3    Pickar, D.4    Breier, A.5
  • 2
    • 0027394523 scopus 로고
    • Altered distribution of nicotinamide-adenine dinucleotide phosphate-diaphorase cells in frontal lobe of schizophrenics implies disturbances of cortical development
    • Akbarian S., Bunney W.E.J., Potkin S.G., Wigal S.B., Hagman J.O., Sandman C.A., Jones E.G. Altered distribution of nicotinamide-adenine dinucleotide phosphate-diaphorase cells in frontal lobe of schizophrenics implies disturbances of cortical development. Arch. Gen. Psychiatry. 50:1993;169-177.
    • (1993) Arch. Gen. Psychiatry , vol.50 , pp. 169-177
    • Akbarian, S.1    Bunney, W.E.J.2    Potkin, S.G.3    Wigal, S.B.4    Hagman, J.O.5    Sandman, C.A.6    Jones, E.G.7
  • 3
    • 0028948389 scopus 로고
    • Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics
    • Akbarian S., Kim J.J., Potkin S.G., Hagman J.O., Tafazzoli A., Bunney W.E.J., Jones E.G. Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics. Arch. Gen. Psychiatry. 52:1995;258-278.
    • (1995) Arch. Gen. Psychiatry , vol.52 , pp. 258-278
    • Akbarian, S.1    Kim, J.J.2    Potkin, S.G.3    Hagman, J.O.4    Tafazzoli, A.5    Bunney, W.E.J.6    Jones, E.G.7
  • 4
    • 0027405968 scopus 로고
    • Distorted distribution of nicotinamide-adenine dinucleotide phosphate-diaphorase neurons in temporal lobe of schizophrenics implies anomalous cortical development
    • Akbarian S., Vinuela A., Kim J.J., Potkin S.G., Bunney W.E.J., Jones E.G. Distorted distribution of nicotinamide-adenine dinucleotide phosphate-diaphorase neurons in temporal lobe of schizophrenics implies anomalous cortical development. Arch. Gen. Psychiatry. 50:1993;178-187.
    • (1993) Arch. Gen. Psychiatry , vol.50 , pp. 178-187
    • Akbarian, S.1    Vinuela, A.2    Kim, J.J.3    Potkin, S.G.4    Bunney, W.E.J.5    Jones, E.G.6
  • 5
    • 0028356042 scopus 로고
    • Methamphetamine-induced behavioral sensitization and its implications for relapse of schizophrenia
    • Akiyama K., Kanzaki A., Tsuchida K., Ujike H. Methamphetamine-induced behavioral sensitization and its implications for relapse of schizophrenia. Schizophr. Res. 12:1994;251-257.
    • (1994) Schizophr. Res. , vol.12 , pp. 251-257
    • Akiyama, K.1    Kanzaki, A.2    Tsuchida, K.3    Ujike, H.4
  • 7
  • 8
    • 0026467216 scopus 로고
    • Hypofrontality in neuroleptic-naive patients and in patients with chronic schizophrenia
    • Andreasen N.C., Rezai K., Alliger R. Hypofrontality in neuroleptic-naive patients and in patients with chronic schizophrenia. Arch. Gen. Psychiatry. 19:1992;943-958.
    • (1992) Arch. Gen. Psychiatry , vol.19 , pp. 943-958
    • Andreasen, N.C.1    Rezai, K.2    Alliger, R.3
  • 9
    • 0014770992 scopus 로고
    • The phenomenology of experimentally-induced amphetamine psychosis - Preliminary observations
    • Angrist B., Gerson S. The phenomenology of experimentally-induced amphetamine psychosis - preliminary observations. Biol. Psychiatry. 2:1970;95-107.
    • (1970) Biol. Psychiatry , vol.2 , pp. 95-107
    • Angrist, B.1    Gerson, S.2
  • 10
    • 0018839978 scopus 로고
    • Responses to apomorphine, amphetamine, and neuroleptics in schizophrenic subjects
    • Angrist B., Rotrosen J., Gershon S. Responses to apomorphine, amphetamine, and neuroleptics in schizophrenic subjects. Psychopharmacology. 67:1980;31-38.
    • (1980) Psychopharmacology , vol.67 , pp. 31-38
    • Angrist, B.1    Rotrosen, J.2    Gershon, S.3
  • 11
    • 0020629581 scopus 로고
    • The dissociative anesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurons by N-methyl-aspartate
    • Anis N.A., Berry S.C., Burton N.R., Lodge D. The dissociative anesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurons by N-methyl-aspartate. Br. J. Pharmacol. 79:1983;565-575.
    • (1983) Br. J. Pharmacol. , vol.79 , pp. 565-575
    • Anis, N.A.1    Berry, S.C.2    Burton, N.R.3    Lodge, D.4
  • 12
    • 0018874396 scopus 로고
    • Interchangeability of stress and amphetamine in sensitization
    • Antelman S.M., Eichler A.J., Black C.A., Kocan D. Interchangeability of stress and amphetamine in sensitization. Science. 207:1980;329-331.
    • (1980) Science , vol.207 , pp. 329-331
    • Antelman, S.M.1    Eichler, A.J.2    Black, C.A.3    Kocan, D.4
  • 13
    • 0030881619 scopus 로고    scopus 로고
    • Clozapine and haloperidol modulate N-methyl-D-aspartate- And non-N-methyl-D-aspartate receptor-mediated neurotransmission in rat prefrontal cortical neurons in vitro
    • Arvanov V.L., Liang X., Schwartz J., Grossman S., Wang R.Y. Clozapine and haloperidol modulate N-methyl-D-aspartate- and non-N-methyl-D-aspartate receptor-mediated neurotransmission in rat prefrontal cortical neurons in vitro. J. Pharmacol. Exp. Ther. 283:1997;226-234.
    • (1997) J. Pharmacol. Exp. Ther. , vol.283 , pp. 226-234
    • Arvanov, V.L.1    Liang, X.2    Schwartz, J.3    Grossman, S.4    Wang, R.Y.5
  • 14
    • 0011820659 scopus 로고
    • Observations on the psychotomimetic effects of sernyl
    • Bakker C.B., Amini F.B. Observations on the psychotomimetic effects of sernyl. Compr. Psychiatry. 2:1961;269-280.
    • (1961) Compr. Psychiatry , vol.2 , pp. 269-280
    • Bakker, C.B.1    Amini, F.B.2
  • 15
    • 0029563620 scopus 로고
    • Antagonism of phencyclidine-induced deficits in prepulse inhibition by the putative atypical antipsychotic olanzapine
    • Bakshi V., Geyer M.A. Antagonism of phencyclidine-induced deficits in prepulse inhibition by the putative atypical antipsychotic olanzapine. Psychopharmacology. 122:1995;198-201.
    • (1995) Psychopharmacology , vol.122 , pp. 198-201
    • Bakshi, V.1    Geyer, M.A.2
  • 16
    • 0028143103 scopus 로고    scopus 로고
    • Clozapine antagonizes phencyclidine-induced deficits in sensorimotor gating of the startle response
    • V.P. Bakshi, N.R. Swerdlow, M.A. Geyer, Clozapine antagonizes phencyclidine-induced deficits in sensorimotor gating of the startle response, J. Pharmacol. Exp. Ther. 271, 787-794.
    • J. Pharmacol. Exp. Ther. , vol.271 , pp. 787-794
    • Bakshi, V.P.1    Swerdlow, N.R.2    Geyer, M.A.3
  • 17
    • 0028837328 scopus 로고
    • Conditioned fear-induced changes in behavior and in the expression of the immediate early gene c-fos with and without diazepam pretreatment
    • Beck C.H.M., Fibiger H.C. Conditioned fear-induced changes in behavior and in the expression of the immediate early gene c-fos with and without diazepam pretreatment. Neuroscience. 15:1995;709-720.
    • (1995) Neuroscience , vol.15 , pp. 709-720
    • Beck, C.H.M.1    Fibiger, H.C.2
  • 18
    • 84873777641 scopus 로고
    • Comparison of amphetamine psychosis and schizophrenia
    • Bell D. Comparison of amphetamine psychosis and schizophrenia. Am. J. Psychiatry. 111:1965;701-707.
    • (1965) Am. J. Psychiatry , vol.111 , pp. 701-707
    • Bell, D.1
  • 19
    • 0029645987 scopus 로고
    • Development of the glutamate, GABA and dopamine systems in relation to NRH-induced neurotoxicity
    • Benes F.M. Development of the glutamate, GABA and dopamine systems in relation to NRH-induced neurotoxicity. Biol. Psychiatry. 38:1995;783-787.
    • (1995) Biol. Psychiatry , vol.38 , pp. 783-787
    • Benes, F.M.1
  • 20
    • 84970312243 scopus 로고
    • Is there a neuroanatomic basis for schizophrenia? An old question revisited
    • Benes F.M. Is there a neuroanatomic basis for schizophrenia? An old question revisited. The Neuroscientist. 1:1995;104-115.
    • (1995) The Neuroscientist , vol.1 , pp. 104-115
    • Benes, F.M.1
  • 21
    • 0027408221 scopus 로고
    • Advancing a neurodevelopmental origin for schizophrenia
    • Bloom F.E. Advancing a neurodevelopmental origin for schizophrenia. Arch. Gen. Psychiatry. 50:1993;224-227.
    • (1993) Arch. Gen. Psychiatry , vol.50 , pp. 224-227
    • Bloom, F.E.1
  • 22
    • 0027283411 scopus 로고
    • Recent advances in the neuropathology of schizophrenia
    • Bogerts B. Recent advances in the neuropathology of schizophrenia. Schizophr. Bull. 19:1993;431-445.
    • (1993) Schizophr. Bull. , vol.19 , pp. 431-445
    • Bogerts, B.1
  • 23
  • 24
    • 0031947285 scopus 로고    scopus 로고
    • Effects of NMDA antagonism on striatal dopamine release in healthy subjects - Application of a novel PET approach
    • Breier A., Adler C.M., Weisenfeld N., Su T.P., Elman I., Picken L., Malhortra A.K., Pickar D. Effects of NMDA antagonism on striatal dopamine release in healthy subjects - application of a novel PET approach. Synapse. 29:1998;142-147.
    • (1998) Synapse , vol.29 , pp. 142-147
    • Breier, A.1    Adler, C.M.2    Weisenfeld, N.3    Su, T.P.4    Elman, I.5    Picken, L.6    Malhortra, A.K.7    Pickar, D.8
  • 25
    • 0030966452 scopus 로고    scopus 로고
    • Association of ketamine-induced psychosis with focal activation of the prefrontal cortex in healthy volunteers
    • A. Breier, A.K. Malhortra, D.A. Pinals, N.I. Weisenfeld, D. Pickar, Association of ketamine-induced psychosis with focal activation of the prefrontal cortex in healthy volunteers, Am. J. Psychiatry 154, 805-811.
    • Am. J. Psychiatry , vol.154 , pp. 805-811
    • Breier, A.1    Malhortra, A.K.2    Pinals, D.A.3    Weisenfeld, N.I.4    Pickar, D.5
  • 27
    • 0027521003 scopus 로고
    • The glycine/NMDA receptor antagonist, R-(+)-HA-966, blocks activation of the mesolimbic dopaminergic system induced by phencyclidine and dizocilpine (MK-801) in rodents
    • Bristow L.J., Hutson P.H., Thorn L., Tricklebank M.D. The glycine/NMDA receptor antagonist, R-(+)-HA-966, blocks activation of the mesolimbic dopaminergic system induced by phencyclidine and dizocilpine (MK-801) in rodents. Br. J. Pharmacol. 108:1993;1156-1163.
    • (1993) Br. J. Pharmacol. , vol.108 , pp. 1156-1163
    • Bristow, L.J.1    Hutson, P.H.2    Thorn, L.3    Tricklebank, M.D.4
  • 28
    • 0014326117 scopus 로고
    • Crises and life changes and the onset of schizophrenia
    • Brown G.W., Birley J.L.T. Crises and life changes and the onset of schizophrenia. J. Health Soc. Behav. 9:1968;203-214.
    • (1968) J. Health Soc. Behav. , vol.9 , pp. 203-214
    • Brown, G.W.1    Birley, J.L.T.2
  • 29
    • 0026498964 scopus 로고
    • Differential behavioral and neurochemical effects of competitive and non-competitive NMDA receptor antagonists in rats
    • Bubser M., Keseberg U., Notz P.K., Schmidt W.J. Differential behavioral and neurochemical effects of competitive and non-competitive NMDA receptor antagonists in rats. Eur. J. Pharmacol. 229:1992;75-82.
    • (1992) Eur. J. Pharmacol. , vol.229 , pp. 75-82
    • Bubser, M.1    Keseberg, U.2    Notz, P.K.3    Schmidt, W.J.4
  • 30
    • 0018116725 scopus 로고
    • Acute and chronic haloperidol treatment comparison of effects on nigral dopaminergic cell activity
    • Bunney B.S., Grace A.A. Acute and chronic haloperidol treatment comparison of effects on nigral dopaminergic cell activity. Life Sci. 23:1978;1715-1728.
    • (1978) Life Sci. , vol.23 , pp. 1715-1728
    • Bunney, B.S.1    Grace, A.A.2
  • 31
    • 0026687845 scopus 로고
    • Regulation of excitatory amino acid release by N-methyl-D-aspartate receptors in rat striatum: In vivo microdialysis studies
    • Bustos G., Abarca J., Forray M.I., Gysling K., Bradberry C.W., Roth R.H. Regulation of excitatory amino acid release by N-methyl-D-aspartate receptors in rat striatum: in vivo microdialysis studies. Brain Res. 585:1992;105-115.
    • (1992) Brain Res. , vol.585 , pp. 105-115
    • Bustos, G.1    Abarca, J.2    Forray, M.I.3    Gysling, K.4    Bradberry, C.W.5    Roth, R.H.6
  • 32
    • 0025363344 scopus 로고
    • Interactions between glutamatergic and monoaminergic systems within the basal ganglia - Implications for schizophrenia and Parkinson's disease
    • Carlsson M., Carlsson A. Interactions between glutamatergic and monoaminergic systems within the basal ganglia - implications for schizophrenia and Parkinson's disease. Trends. Neurosci. 13:1990;272-276.
    • (1990) Trends. Neurosci. , vol.13 , pp. 272-276
    • Carlsson, M.1    Carlsson, A.2
  • 33
    • 0027422087 scopus 로고
    • Are the disparate pharmacological profiles of competitive and un-competitive NMDA antagonists due to different baseline activities of distinct glutaminergic pathways?
    • Carlsson M.L. Are the disparate pharmacological profiles of competitive and un-competitive NMDA antagonists due to different baseline activities of distinct glutaminergic pathways? J. Neural Transm. 94:1993;1-10.
    • (1993) J. Neural Transm. , vol.94 , pp. 1-10
    • Carlsson, M.L.1
  • 34
    • 0024501249 scopus 로고
    • The NMDA antagonist, MK-801 causes marked locomotor stimulation in monamine-depleted mice
    • Carlsson M.L., Carlsson A. The NMDA antagonist, MK-801 causes marked locomotor stimulation in monamine-depleted mice. J. Neural Transm. 75:1989;221-226.
    • (1989) J. Neural Transm. , vol.75 , pp. 221-226
    • Carlsson, M.L.1    Carlsson, A.2
  • 37
    • 0024165163 scopus 로고
    • The heterogeneity of the long term course of schizophrenia
    • Carpenter W.T. Jr., Kirkpatrick B. The heterogeneity of the long term course of schizophrenia. Schizophr. Bull. 14:1988;645-652.
    • (1988) Schizophr. Bull. , vol.14 , pp. 645-652
    • Carpenter W.T., Jr.1    Kirkpatrick, B.2
  • 38
    • 0021706490 scopus 로고
    • Midazolam and diazepam in ketamine anesthesia
    • Cartwright P.D., Pingel S.M. Midazolam and diazepam in ketamine anesthesia. Anaesthesia. 59:1984;439-442.
    • (1984) Anaesthesia , vol.59 , pp. 439-442
    • Cartwright, P.D.1    Pingel, S.M.2
  • 39
    • 0001979163 scopus 로고
    • Comparison of phencyclidine hydrochloride (sernyl) with other drugs: Simulation of schizophrenic performance with phencyclidine hydrochloride (sernyl)lysergic acid diethylamide (LSD-25), and amobarbital (Amytal) sodium: II. Symbolic and sequential thinking
    • Cohen B.D., Rosenbaum G., Luby E.D., Gottlieb J.S. Comparison of phencyclidine hydrochloride (sernyl) with other drugs: simulation of schizophrenic performance with phencyclidine hydrochloride (sernyl)lysergic acid diethylamide (LSD-25), and amobarbital (Amytal) sodium: II. Symbolic and sequential thinking. Arch. Gen. Psychiatry. 6:1962;79-85.
    • (1962) Arch. Gen. Psychiatry , vol.6 , pp. 79-85
    • Cohen, B.D.1    Rosenbaum, G.2    Luby, E.D.3    Gottlieb, J.S.4
  • 42
    • 0025922679 scopus 로고
    • High central D2-dopamine receptor occupancy as assessed with positron emission tomography in medicated but therapy-resistant schizophrenic patients
    • Coppens H.J., Slooff C.J., Paans A.M., Wiegman T., Vaalburg W., Korf J. High central D2-dopamine receptor occupancy as assessed with positron emission tomography in medicated but therapy-resistant schizophrenic patients. Biol. Psychiatry. 29:1991;629-634.
    • (1991) Biol. Psychiatry , vol.29 , pp. 629-634
    • Coppens, H.J.1    Slooff, C.J.2    Paans, A.M.3    Wiegman, T.4    Vaalburg, W.5    Korf, J.6
  • 44
    • 0013874766 scopus 로고
    • Dissociative anesthesia: Further pharmacologic studies and first clinical experience with phencyclidine derivative Cl-581
    • Corssen G., Domino E.F. Dissociative anesthesia: further pharmacologic studies and first clinical experience with phencyclidine derivative Cl-581. Anesth. Analg. 45:1966;29-40.
    • (1966) Anesth. Analg. , vol.45 , pp. 29-40
    • Corssen, G.1    Domino, E.F.2
  • 45
    • 0030044715 scopus 로고    scopus 로고
    • The glutamatergic dysfunction hypothesis for schizophrenia
    • Coyle J.T. The glutamatergic dysfunction hypothesis for schizophrenia. Harvard Review of Psychiatry. 3:1996;241-253.
    • (1996) Harvard Review of Psychiatry , vol.3 , pp. 241-253
    • Coyle, J.T.1
  • 46
    • 0017255979 scopus 로고
    • Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs
    • Creese I., Burt D.R., Snyder S.H. Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs. Science. 192:1976;480-483.
    • (1976) Science , vol.192 , pp. 480-483
    • Creese, I.1    Burt, D.R.2    Snyder, S.H.3
  • 47
    • 0027366620 scopus 로고
    • Evidence for involvement of brain dopamine and other mechanisms in the behavioral action of the N-methyl-D- aspartic acid antagonist MK-801 in control and 6-hydroxydopamine-lesioned rats
    • Criswell H.E., Johnson K.B., Mueller R.A., Breese G.R. Evidence for involvement of brain dopamine and other mechanisms in the behavioral action of the N-methyl-D- aspartic acid antagonist MK-801 in control and 6-hydroxydopamine-lesioned rats. J. Pharmacol. Exp. Ther. 265:1993;1001-1010.
    • (1993) J. Pharmacol. Exp. Ther. , vol.265 , pp. 1001-1010
    • Criswell, H.E.1    Johnson, K.B.2    Mueller, R.A.3    Breese, G.R.4
  • 48
    • 0020038157 scopus 로고
    • Local changes in cerebral glucose utilization during ketamine anesthesia
    • Crosby G., Crane A.M., Sokoloff L. Local changes in cerebral glucose utilization during ketamine anesthesia. Anesthesiology. 56:1982;437-443.
    • (1982) Anesthesiology , vol.56 , pp. 437-443
    • Crosby, G.1    Crane, A.M.2    Sokoloff, L.3
  • 49
    • 0018899460 scopus 로고
    • Molecular pathology of schizophrenia: More than one dimension of pathology?
    • Crow T.J. Molecular pathology of schizophrenia: more than one dimension of pathology? BMJ. 280:1980;66-68.
    • (1980) BMJ , vol.280 , pp. 66-68
    • Crow, T.J.1
  • 50
    • 0025649549 scopus 로고
    • Temporal lobe asymmetries as the key to the etiology of schizophrenia
    • Crow T.J. Temporal lobe asymmetries as the key to the etiology of schizophrenia. Schizophr. Bull. 16:1990;433-443.
    • (1990) Schizophr. Bull. , vol.16 , pp. 433-443
    • Crow, T.J.1
  • 52
    • 0025292724 scopus 로고
    • Sensitization vs. tolerance to the dopamine turnover elevating effects of haloperidol the effect of regular/intermittent dosing
    • Csernansky J.G., Bellows E.P., Barnes D.E., Lombrozo L. Sensitization vs. tolerance to the dopamine turnover elevating effects of haloperidol the effect of regular/intermittent dosing. Psychopharmacology. 101:1990;519-524.
    • (1990) Psychopharmacology , vol.101 , pp. 519-524
    • Csernansky, J.G.1    Bellows, E.P.2    Barnes, D.E.3    Lombrozo, L.4
  • 53
    • 0028894469 scopus 로고
    • Pattern and time course of immediate early gene expression in rat brain following acute stress
    • Cullinan W.E., Herman J.P., Battaglia D.F., Akil H., Watson S.J. Pattern and time course of immediate early gene expression in rat brain following acute stress. Neuroscience. 64:1995;477-505.
    • (1995) Neuroscience , vol.64 , pp. 477-505
    • Cullinan, W.E.1    Herman, J.P.2    Battaglia, D.F.3    Akil, H.4    Watson, S.J.5
  • 54
    • 70449327565 scopus 로고
    • The effect of 1-arylcyclohexylamine (sernyl) on twelve normal volunteers
    • Davies B.M., Beech H.R. The effect of 1-arylcyclohexylamine (sernyl) on twelve normal volunteers. J. Ment. Sci. 106:1960;912-924.
    • (1960) J. Ment. Sci. , vol.106 , pp. 912-924
    • Davies, B.M.1    Beech, H.R.2
  • 55
    • 0026070134 scopus 로고
    • Dopamine in schizophrenia: A review and reconceptualization
    • Davis K.L., Kahn R.S., Ko G., Davidson M. Dopamine in schizophrenia: a review and reconceptualization. Am. J. Psychiatry. 148:1991;1474-1486.
    • (1991) Am. J. Psychiatry , vol.148 , pp. 1474-1486
    • Davis, K.L.1    Kahn, R.S.2    Ko, G.3    Davidson, M.4
  • 57
    • 0026611392 scopus 로고
    • The regulation of subcortical dopamine systems by the prefrontal cortex interactions of central dopamine systems and the pathogenesis of schizophrenia
    • Deutch A.Y. The regulation of subcortical dopamine systems by the prefrontal cortex interactions of central dopamine systems and the pathogenesis of schizophrenia. J. Neural Transm. Suppl. 36:1992;61-89.
    • (1992) J. Neural Transm. Suppl. , vol.36 , pp. 61-89
    • Deutch, A.Y.1
  • 59
    • 77952810889 scopus 로고
    • Pharmacological effects of CI-581, a new dissociative anesthetic in man
    • Domino E.F., Chodoff P., Corssen G. Pharmacological effects of CI-581, a new dissociative anesthetic in man. Clin. Pharmacol. Ther. 6:1965;279-291.
    • (1965) Clin. Pharmacol. Ther. , vol.6 , pp. 279-291
    • Domino, E.F.1    Chodoff, P.2    Corssen, G.3
  • 60
    • 0027965383 scopus 로고
    • Childhood antecedents of schizophrenia and affective illness social adjustment at ages 7 and 11
    • Done D.J., Crow T.J., Johnstone E.C., Sacker A. Childhood antecedents of schizophrenia and affective illness social adjustment at ages 7 and 11. BMJ. 309:1994;699-703.
    • (1994) BMJ , vol.309 , pp. 699-703
    • Done, D.J.1    Crow, T.J.2    Johnstone, E.C.3    Sacker, A.4
  • 61
    • 0027181351 scopus 로고
    • Topographic patterns of brain activity in response to swim stress: Assessment by 2-deoxyglucose uptake and expression of Fos-like immunoreactivity
    • Duncan G.E., Johnson K.B., Breese G.R.T. Topographic patterns of brain activity in response to swim stress: assessment by 2-deoxyglucose uptake and expression of Fos-like immunoreactivity. J. Neurosci. 13:1993;3932-3943.
    • (1993) J. Neurosci. , vol.13 , pp. 3932-3943
    • Duncan, G.E.1    Johnson, K.B.2    Breese, G.R.T.3
  • 62
    • 0029868295 scopus 로고    scopus 로고
    • Neuroanatomical characterization of Fos induction in rat behavioral models of anxiety
    • Duncan G.E., Knapp D.J., Breese G.R. Neuroanatomical characterization of Fos induction in rat behavioral models of anxiety. Brain Res. 713:1996;79-91.
    • (1996) Brain Res. , vol.713 , pp. 79-91
    • Duncan, G.E.1    Knapp, D.J.2    Breese, G.R.3
  • 63
    • 0030423668 scopus 로고    scopus 로고
    • Functional classification of antidepressants based upon antagonism of swim stress-induced Fos-like immunoreactivity
    • Duncan G.E., Knapp D.J., Johnson K.B., Breese G.R. Functional classification of antidepressants based upon antagonism of swim stress-induced Fos-like immunoreactivity. J. Pharmacol. Exp. Ther. 277:1996;1076-1089.
    • (1996) J. Pharmacol. Exp. Ther. , vol.277 , pp. 1076-1089
    • Duncan, G.E.1    Knapp, D.J.2    Johnson, K.B.3    Breese, G.R.4
  • 65
    • 0032561707 scopus 로고    scopus 로고
    • Differential effects of clozapine and haloperidol on ketamine-induced brain metabolic activation
    • Duncan G.E., Leipzig J.N., Mailman R.B., Lieberman J.A. Differential effects of clozapine and haloperidol on ketamine-induced brain metabolic activation. Brain Res. 812:1998;65-75.
    • (1998) Brain Res. , vol.812 , pp. 65-75
    • Duncan, G.E.1    Leipzig, J.N.2    Mailman, R.B.3    Lieberman, J.A.4
  • 66
    • 0032559875 scopus 로고    scopus 로고
    • Metabolic mapping of the rat brain after subanesthetic doses of ketamine: Potential relevance to schizophrenia
    • Duncan G.E., Moy S.S., Knapp D.J., Mueller R.A., Breese G.R. Metabolic mapping of the rat brain after subanesthetic doses of ketamine: potential relevance to schizophrenia. Brain Res. 787:1998;181-190.
    • (1998) Brain Res. , vol.787 , pp. 181-190
    • Duncan, G.E.1    Moy, S.S.2    Knapp, D.J.3    Mueller, R.A.4    Breese, G.R.5
  • 67
    • 0018199544 scopus 로고
    • Ketamine-lorazepam: Attenuation of the psychic sequelae of ketamine by lorazepam
    • Dundee J.W., Lilburn J.K. Ketamine-lorazepam: attenuation of the psychic sequelae of ketamine by lorazepam. Anaesthesia. 37:1977;312-314.
    • (1977) Anaesthesia , vol.37 , pp. 312-314
    • Dundee, J.W.1    Lilburn, J.K.2
  • 68
    • 0018146493 scopus 로고
    • Long term changes in dopaminergic innervation of caudate nucleus after continuous amphetamine administration
    • Ellison G.D., Eison M., Huberman H., Daniel F. Long term changes in dopaminergic innervation of caudate nucleus after continuous amphetamine administration. Science. 201:1978;276-278.
    • (1978) Science , vol.201 , pp. 276-278
    • Ellison, G.D.1    Eison, M.2    Huberman, H.3    Daniel, F.4
  • 69
    • 0023520175 scopus 로고
    • High-risk research in schizophrenia: A summary of what has been learned
    • Erlenmeyer-Kimling L., Cornblatt B. High-risk research in schizophrenia: a summary of what has been learned. J. Psychiatr. Res. 21:1987;401-411.
    • (1987) J. Psychiatr. Res. , vol.21 , pp. 401-411
    • Erlenmeyer-Kimling, L.1    Cornblatt, B.2
  • 70
    • 0030608074 scopus 로고    scopus 로고
    • Olanzapine and fluperlapine mimic clozapine in preventing MK-801 neurotoxicity
    • Farber N.B., Foster J., Duhan N.L., Olney J.W. Olanzapine and fluperlapine mimic clozapine in preventing MK-801 neurotoxicity. Schizophr. Res. 21:1996;13-37.
    • (1996) Schizophr. Res. , vol.21 , pp. 13-37
    • Farber, N.B.1    Foster, J.2    Duhan, N.L.3    Olney, J.W.4
  • 72
    • 0029646097 scopus 로고
    • Age-specific neurotoxicity in the rat associated with NMDA receptor blockade, potential relevance to schizophrenia
    • Farber N.B., Wozniak D.F., Price M.T., Labruyere J., Huss J., St. Peter H., Olney J.W. Age-specific neurotoxicity in the rat associated with NMDA receptor blockade, potential relevance to schizophrenia. Biol. Psychiatry. 38:1995;788-796.
    • (1995) Biol. Psychiatry , vol.38 , pp. 788-796
    • Farber, N.B.1    Wozniak, D.F.2    Price, M.T.3    Labruyere, J.4    Huss, J.5    St. Peter, H.6    Olney, J.W.7
  • 73
    • 0026718710 scopus 로고
    • Positron emission tomographic analysis of central D1 and D2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine relation to extrapyramidal side effects
    • Farde L., Nordstrom A.L., Wiesel F.A., Pauli S., Halldin C., Sedvall G. Positron emission tomographic analysis of central D1 and D2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine relation to extrapyramidal side effects. Arch. Gen. Psychiatry. 49:1992;538-544.
    • (1992) Arch. Gen. Psychiatry , vol.49 , pp. 538-544
    • Farde, L.1    Nordstrom, A.L.2    Wiesel, F.A.3    Pauli, S.4    Halldin, C.5    Sedvall, G.6
  • 74
    • 0020390010 scopus 로고
    • Schizophrenia caused by a fault in programmed synaptic elimination during adolescence?
    • Feinberg I. Schizophrenia caused by a fault in programmed synaptic elimination during adolescence? J. Psychiatr. Res. 17:1982;319-334.
    • (1982) J. Psychiatr. Res. , vol.17 , pp. 319-334
    • Feinberg, I.1
  • 75
    • 0015851928 scopus 로고
    • Ketamine-induced electroconvulsive phenomena in human limbic and thalamic regions
    • Ferrer-Allado T., Brechner V.L., Dymond A., Cozen H., Crandall P. Ketamine-induced electroconvulsive phenomena in human limbic and thalamic regions. Anesthesiology. 38:1973;333-344.
    • (1973) Anesthesiology , vol.38 , pp. 333-344
    • Ferrer-Allado, T.1    Brechner, V.L.2    Dymond, A.3    Cozen, H.4    Crandall, P.5
  • 76
    • 0017745689 scopus 로고
    • Neurobiologic antecedents of schizophrenia in children: Evidence for an inherited, congenital neurointegrative defect
    • Fish B. Neurobiologic antecedents of schizophrenia in children: evidence for an inherited, congenital neurointegrative defect. Arch. Gen. Psychiatry. 34:1977;1297-1313.
    • (1977) Arch. Gen. Psychiatry , vol.34 , pp. 1297-1313
    • Fish, B.1
  • 77
    • 0021165497 scopus 로고
    • The effects of phencyclidine and N-allylnormetazocine on midbrain dopamine neuronal activity
    • Freeman A.S., Bunney B.S. The effects of phencyclidine and N-allylnormetazocine on midbrain dopamine neuronal activity. Eur. J. Pharmacol. 104:1984;287-293.
    • (1984) Eur. J. Pharmacol. , vol.104 , pp. 287-293
    • Freeman, A.S.1    Bunney, B.S.2
  • 78
    • 0022638959 scopus 로고
    • Effects of phencyclidine on ventral tegmental A10 dopamine neurons in the rat
    • French E.D. Effects of phencyclidine on ventral tegmental A10 dopamine neurons in the rat. Neuropharmacology. 25:1986;241-248.
    • (1986) Neuropharmacology , vol.25 , pp. 241-248
    • French, E.D.1
  • 79
    • 0025077739 scopus 로고
    • Non-competitive N-methyl-D-aspartate antagonists are potent activators of ventral tegmental A10 dopamine neurons
    • French E.D., Ceci A. Non-competitive N-methyl-D-aspartate antagonists are potent activators of ventral tegmental A10 dopamine neurons. Neurosci. Lett. 119:1990;159-162.
    • (1990) Neurosci. Lett. , vol.119 , pp. 159-162
    • French, E.D.1    Ceci, A.2
  • 80
    • 0025788614 scopus 로고
    • Effects of competitive N-methyl-D-aspartate antagonists on midbrain dopamine neurons - An electrophysiological and behavioral comparison to phencyclidine
    • French E.D., Ferkany J., Abreu M., Levenson S. Effects of competitive N-methyl-D-aspartate antagonists on midbrain dopamine neurons - an electrophysiological and behavioral comparison to phencyclidine. Neuropharmacology. 30:1991;1039-1046.
    • (1991) Neuropharmacology , vol.30 , pp. 1039-1046
    • French, E.D.1    Ferkany, J.2    Abreu, M.3    Levenson, S.4
  • 81
    • 0030773618 scopus 로고    scopus 로고
    • Glutamate in schizophrenia: Clinical and research implications (review)
    • Goff D.C., Wine L. Glutamate in schizophrenia: clinical and research implications (review). Schizophr. Res. 27:1997;157-168.
    • (1997) Schizophr. Res. , vol.27 , pp. 157-168
    • Goff, D.C.1    Wine, L.2
  • 82
    • 0026059697 scopus 로고
    • Phasic vs. tonic dopamine release and the modulation of dopamine system responsivity a hypothesis for the etiology of schizophrenia
    • Grace A.A. Phasic vs. tonic dopamine release and the modulation of dopamine system responsivity a hypothesis for the etiology of schizophrenia. Neuroscience. 41:1991;1-24.
    • (1991) Neuroscience , vol.41 , pp. 1-24
    • Grace, A.A.1
  • 83
    • 0027213196 scopus 로고
    • Cortical regulation of subcortical dopamine systems and its possible relevance to schizophrenia
    • Grace A.A. Cortical regulation of subcortical dopamine systems and its possible relevance to schizophrenia. J. Neural Transm. 91:1993;111-134.
    • (1993) J. Neural Transm. , vol.91 , pp. 111-134
    • Grace, A.A.1
  • 84
    • 0028837465 scopus 로고
    • The tonic/phasic model of dopamine system regulation: Its relevance for understanding how stimulant abuse can alter basal ganglia function
    • Grace A.A. The tonic/phasic model of dopamine system regulation: its relevance for understanding how stimulant abuse can alter basal ganglia function. Drug Alcohol Depend. 37:1995;111-129.
    • (1995) Drug Alcohol Depend. , vol.37 , pp. 111-129
    • Grace, A.A.1
  • 85
    • 0021718376 scopus 로고
    • The control of firing pattern in nigral dopamine neurons burst firing
    • Grace A.A., Bunney B.S. The control of firing pattern in nigral dopamine neurons burst firing. J. Neurosci. 4:1984;2877-2890.
    • (1984) J. Neurosci. , vol.4 , pp. 2877-2890
    • Grace, A.A.1    Bunney, B.S.2
  • 86
  • 88
    • 1842415378 scopus 로고    scopus 로고
    • Epidemiology of schizophrenia
    • Hafner H., An D.H. Epidemiology of schizophrenia. Can. J. Psychiatry. 42:1997;139-151.
    • (1997) Can. J. Psychiatry , vol.42 , pp. 139-151
    • Hafner, H.1    An, D.H.2
  • 90
    • 0027281102 scopus 로고
    • Enhanced stress-induced dopamine release in the prefrontal cortex of amphetamine-sensitized rats
    • Hamamura T., Fibiger H.C.E. Enhanced stress-induced dopamine release in the prefrontal cortex of amphetamine-sensitized rats. Eur. J. Pharmacol. 237:1993;65-72.
    • (1993) Eur. J. Pharmacol. , vol.237 , pp. 65-72
    • Hamamura, T.1    Fibiger, H.C.E.2
  • 91
    • 0021027426 scopus 로고
    • Altered metabolic activity in the cerebral cortex of rats exposed to ketamine
    • Hammer R.P., Herkenham M. Altered metabolic activity in the cerebral cortex of rats exposed to ketamine. J. Comp. Neurol. 220:1983;396-404.
    • (1983) J. Comp. Neurol. , vol.220 , pp. 396-404
    • Hammer, R.P.1    Herkenham, M.2
  • 92
    • 0027482197 scopus 로고
    • The non-NMA glutamate receptor antagonist GYKI Y1-52466 counteracts locomotor stimulation and anticataleptic activity induced by the NMDA antagonist dizocilpine
    • Hauber W., Andersen R. The non-NMA glutamate receptor antagonist GYKI Y1-52466 counteracts locomotor stimulation and anticataleptic activity induced by the NMDA antagonist dizocilpine. Naunyn-Schmiedeberg's Arch. Pharmacol. 348:1993;486-490.
    • (1993) Naunyn-Schmiedeberg's Arch. Pharmacol. , vol.348 , pp. 486-490
    • Hauber, W.1    Andersen, R.2
  • 93
    • 0026779303 scopus 로고
    • Typical and atypical neuroleptics antagonize MK-801-induced locomotion and stereotypy in rats
    • Hoffman D.C. Typical and atypical neuroleptics antagonize MK-801-induced locomotion and stereotypy in rats. J. Neural Transm. 89:1992;1-10.
    • (1992) J. Neural Transm. , vol.89 , pp. 1-10
    • Hoffman, D.C.1
  • 94
    • 0027953427 scopus 로고
    • Effect of phencyclidine on dopamine release in the rat prefrontal cortex, an in vivo microdialysis study
    • Hondo H., Yonezawa Y., Nakahara T., Nakamura K., Hirano M., Uchimaura H., Tashiro N. Effect of phencyclidine on dopamine release in the rat prefrontal cortex, an in vivo microdialysis study. Brain Res. 633:1994;337-342.
    • (1994) Brain Res. , vol.633 , pp. 337-342
    • Hondo, H.1    Yonezawa, Y.2    Nakahara, T.3    Nakamura, K.4    Hirano, M.5    Uchimaura, H.6    Tashiro, N.7
  • 96
    • 0018376668 scopus 로고
    • Synaptic density in the human frontal cortex - Developmental changes and the effects of aging
    • Huttenlocher P.R. Synaptic density in the human frontal cortex - developmental changes and the effects of aging. Brain Res. 163:1979;195-205.
    • (1979) Brain Res. , vol.163 , pp. 195-205
    • Huttenlocher, P.R.1
  • 98
    • 0025086243 scopus 로고
    • NMDA receptors and in vivo dopamine release in the nucleus accumbens and caudatus
    • Imperato A., Scrocco M.G., Bacchi S., Angelucci L. NMDA receptors and in vivo dopamine release in the nucleus accumbens and caudatus. Eur. J. Pharmacol. 187:1990;555-556.
    • (1990) Eur. J. Pharmacol. , vol.187 , pp. 555-556
    • Imperato, A.1    Scrocco, M.G.2    Bacchi, S.3    Angelucci, L.4
  • 100
    • 0022904075 scopus 로고
    • Prenatal developmental disturbances in the limbic allocortex in schizophrenics
    • Jakob H., Beckmann H. Prenatal developmental disturbances in the limbic allocortex in schizophrenics. J. Neural Transm. 65:1986;303-304.
    • (1986) J. Neural Transm. , vol.65 , pp. 303-304
    • Jakob, H.1    Beckmann, H.2
  • 101
    • 0025243363 scopus 로고
    • Persistent elevations in dopamine and its metabolites in the nucleus accumbens after mild subchronic stress in rats with ibotenic acid lesions of the medial prefrontal cortex
    • Jaskiw G.E., Karoum F., Weinberger D.R. Persistent elevations in dopamine and its metabolites in the nucleus accumbens after mild subchronic stress in rats with ibotenic acid lesions of the medial prefrontal cortex. Brain Res. 534:1990;321-323.
    • (1990) Brain Res. , vol.534 , pp. 321-323
    • Jaskiw, G.E.1    Karoum, F.2    Weinberger, D.R.3
  • 102
    • 0025952455 scopus 로고
    • Recent advances in the phencyclidine model of schizophrenia
    • Javitt D.C., Zukin S.R. Recent advances in the phencyclidine model of schizophrenia. Am. J. Psychiatry. 148:1991;1301-1308.
    • (1991) Am. J. Psychiatry , vol.148 , pp. 1301-1308
    • Javitt, D.C.1    Zukin, S.R.2
  • 103
    • 0030862672 scopus 로고    scopus 로고
    • Enduring cognitive deficits and cortical dopamine dysfunction in monkeys after long-term administration of phencyclidine
    • Jentsch J.D., Redmond D.E.J., Elsworth J.D., Taylor J.R., Youngren K.D., Roth R.H. Enduring cognitive deficits and cortical dopamine dysfunction in monkeys after long-term administration of phencyclidine. Science. 277:1997;953-955.
    • (1997) Science , vol.277 , pp. 953-955
    • Jentsch, J.D.1    Redmond, D.E.J.2    Elsworth, J.D.3    Taylor, J.R.4    Youngren, K.D.5    Roth, R.H.6
  • 104
    • 0031808409 scopus 로고    scopus 로고
    • Subchronic phencyclidine administration increases mesolimbic dopaminergic system responsivity and augments stress- And psychostimulant-induced hyperlocomotion
    • Jentsch J.D., Taylor J.R., Roth R.H. Subchronic phencyclidine administration increases mesolimbic dopaminergic system responsivity and augments stress- and psychostimulant-induced hyperlocomotion. Neuropsychopharmacology. 19:1998;105-113.
    • (1998) Neuropsychopharmacology , vol.19 , pp. 105-113
    • Jentsch, J.D.1    Taylor, J.R.2    Roth, R.H.3
  • 105
    • 0030851961 scopus 로고    scopus 로고
    • Subchronic phencyclidine administration reduces mesoprefrontal dopamine utilization and impairs prefrontal cortical-dependent cognition in the rat
    • Jentsch J.D., Tran A., Le D., Youngren K.D., Roth R.H. Subchronic phencyclidine administration reduces mesoprefrontal dopamine utilization and impairs prefrontal cortical-dependent cognition in the rat. Neuropsychopharmacology. 17:1997;92-99.
    • (1997) Neuropsychopharmacology , vol.17 , pp. 92-99
    • Jentsch, J.D.1    Tran, A.2    Le, D.3    Youngren, K.D.4    Roth, R.H.5
  • 106
    • 0027392598 scopus 로고
    • Time course of extracellular dopamine and behavioral sensitization: II. Dopamine perikarya
    • Kalivas P.W. Time course of extracellular dopamine and behavioral sensitization: II. Dopamine perikarya. J. Neurosci. 13:1993;276-284.
    • (1993) J. Neurosci. , vol.13 , pp. 276-284
    • Kalivas, P.W.1
  • 107
    • 0025751604 scopus 로고
    • Dopamine transmission in the initiation and expression of drug- And stress-induced sensitization of motor activity
    • Kalivas P.W., Stewart J. Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity. Brain Res. Rev. 16:1991;223-244.
    • (1991) Brain Res. Rev. , vol.16 , pp. 223-244
    • Kalivas, P.W.1    Stewart, J.2
  • 108
    • 0002820458 scopus 로고
    • Maintenance pharmacotherapy in schizophrenia
    • in: H.Y. Meltzer (Ed.), Raven Press, New York
    • J.M. Kane, J.A. Lieberman, Maintenance pharmacotherapy in schizophrenia, in: H.Y. Meltzer (Ed.), Psychopharmacology: the 3rd Generation of Progress, Raven Press, New York, 1987, pp. 1103-1109.
    • (1987) Psychopharmacology: The 3rd Generation of Progress , pp. 1103-1109
    • Kane, J.M.1    Lieberman, J.A.2
  • 109
    • 0027215942 scopus 로고
    • In vivo regulation of extracellular dopamine in the neostriatum influence of impulse activity and local excitatory amino acid release
    • Keefe K.A., Zigmond M.J., Abercrombie E.D. In vivo regulation of extracellular dopamine in the neostriatum influence of impulse activity and local excitatory amino acid release. J. Neural Transm. 91:1993;223-240.
    • (1993) J. Neural Transm. , vol.91 , pp. 223-240
    • Keefe, K.A.1    Zigmond, M.J.2    Abercrombie, E.D.3
  • 110
    • 0027216273 scopus 로고
    • The genetics of schizophrenia - A current, genetic-epidemiologic perspective
    • Kendler K.S., Diehl S.R. The genetics of schizophrenia - a current, genetic-epidemiologic perspective. Schizophr. Bull. 19:1993;261-285.
    • (1993) Schizophr. Bull. , vol.19 , pp. 261-285
    • Kendler, K.S.1    Diehl, S.R.2
  • 111
    • 0028331326 scopus 로고
    • The new atypical antipsychotics - A lack of extrapyramidal side-effects and new routes in schizophrenia research
    • Kerwin R.W. The new atypical antipsychotics - a lack of extrapyramidal side-effects and new routes in schizophrenia research. Br. J. Psychiatry. 164:1994;141-148.
    • (1994) Br. J. Psychiatry , vol.164 , pp. 141-148
    • Kerwin, R.W.1
  • 112
    • 0027325457 scopus 로고
    • Infection and autoimmunity as etiologic factors in schizophrenia - A review and reappraisal
    • Kirch D.G. Infection and autoimmunity as etiologic factors in schizophrenia - a review and reappraisal. Schizophr. Bull. 19:1993;355-370.
    • (1993) Schizophr. Bull. , vol.19 , pp. 355-370
    • Kirch, D.G.1
  • 113
    • 0021746255 scopus 로고
    • A neurohistological correlate of schizophrenia
    • Kovelman J.A., Scheibel A.B. A neurohistological correlate of schizophrenia. Biol. Psychiatry. 19:1984;1601-1621.
    • (1984) Biol. Psychiatry , vol.19 , pp. 1601-1621
    • Kovelman, J.A.1    Scheibel, A.B.2
  • 114
    • 0014222677 scopus 로고
    • Amphetamine abuse - Pattern and effects of high doses taken intravenously
    • Kramer J.C., Gischman V., Littlefield D. Amphetamine abuse - pattern and effects of high doses taken intravenously. J. Am. Med. Assoc. 201:1967;89-93.
    • (1967) J. Am. Med. Assoc. , vol.201 , pp. 89-93
    • Kramer, J.C.1    Gischman, V.2    Littlefield, D.3
  • 117
    • 0024396066 scopus 로고
    • Effects of NMDA antagonists, MK-801 and CPP, upon local cerebral glucose use
    • Kurumaji A., Nehls D.G., Park C.K., McCulloch J. Effects of NMDA antagonists, MK-801 and CPP, upon local cerebral glucose use. Brain Res. 496:1989;268-284.
    • (1989) Brain Res. , vol.496 , pp. 268-284
    • Kurumaji, A.1    Nehls, D.G.2    Park, C.K.3    McCulloch, J.4
  • 118
    • 0028943849 scopus 로고
    • Ketamine activates psychosis and alters limbic blood flow in schizophrenia
    • Lahti A.C., Holcomb H.H., Medoff D.R., Tamminga C.A. Ketamine activates psychosis and alters limbic blood flow in schizophrenia. NeuroReport. 6:1995;869-872.
    • (1995) NeuroReport , vol.6 , pp. 869-872
    • Lahti, A.C.1    Holcomb, H.H.2    Medoff, D.R.3    Tamminga, C.A.4
  • 121
    • 0028006714 scopus 로고
    • Stress reduction in the social environment of schizophrenic patients
    • Leff J. Stress reduction in the social environment of schizophrenic patients. Acta Psychiatrica Scandinavica. 90:1994;133-139.
    • (1994) Acta Psychiatrica Scandinavica , vol.90 , pp. 133-139
    • Leff, J.1
  • 123
    • 0023522707 scopus 로고
    • Obstetrical complications, neurodevelopmental deviance, and risk of schizophrenia
    • Lewis S.W., Murray R.M. Obstetrical complications, neurodevelopmental deviance, and risk of schizophrenia. J. Psychiatr. Res. 21:1987;413-421.
    • (1987) J. Psychiatr. Res. , vol.21 , pp. 413-421
    • Lewis, S.W.1    Murray, R.M.2
  • 125
    • 0026643240 scopus 로고
    • Qualitative assessment of brain morphology in acute and chronic schizophrenia
    • Lieberman J.A., Bogerts B., Degreef G., Ashtari M., Alvir J. Qualitative assessment of brain morphology in acute and chronic schizophrenia. Am. J. Psychiatry. 149:1992;784-794.
    • (1992) Am. J. Psychiatry , vol.149 , pp. 784-794
    • Lieberman, J.A.1    Bogerts, B.2    Degreef, G.3    Ashtari, M.4    Alvir, J.5
  • 126
    • 0023103235 scopus 로고
    • Provocative tests with psychostimulant drugs in schizophrenia
    • Lieberman J.A., Kane J.M., Alvir J.A.J. Provocative tests with psychostimulant drugs in schizophrenia. Psychopharmacology. 91:1987;415-433.
    • (1987) Psychopharmacology , vol.91 , pp. 415-433
    • Lieberman, J.A.1    Kane, J.M.2    Alvir, J.A.J.3
  • 127
    • 0025305036 scopus 로고
    • Dopaminergic mechanisms in idiopathic and drug-induced psychoses
    • Lieberman J.A., Kinon B.J., Loebel A.D. Dopaminergic mechanisms in idiopathic and drug-induced psychoses. Schizophr. Bull. 16:1990;97-109.
    • (1990) Schizophr. Bull. , vol.16 , pp. 97-109
    • Lieberman, J.A.1    Kinon, B.J.2    Loebel, A.D.3
  • 128
    • 0029797948 scopus 로고    scopus 로고
    • Factors influencing treatment response and outcome of first-episode schizophrenia implications for understanding the pathophysiology of schizophrenia
    • Lieberman J.A., Koreen A., Chakos M., Sheitman B., Woerner M., Alvir J., Bilder R. Factors influencing treatment response and outcome of first-episode schizophrenia implications for understanding the pathophysiology of schizophrenia. J. Clin. Psychiatry. 57:1996;5-9.
    • (1996) J. Clin. Psychiatry , vol.57 , pp. 5-9
    • Lieberman, J.A.1    Koreen, A.2    Chakos, M.3    Sheitman, B.4    Woerner, M.5    Alvir, J.6    Bilder, R.7
  • 129
    • 0030774502 scopus 로고    scopus 로고
    • Neurochemical sensitization in the pathophysiology of schizophrenia deficits and dysfunction in neuronal regulation and plasticity
    • Lieberman J.A., Sheitman B.B., Kinon B.J. Neurochemical sensitization in the pathophysiology of schizophrenia deficits and dysfunction in neuronal regulation and plasticity. Neuropsychopharmacology. 17:1997;205-229.
    • (1997) Neuropsychopharmacology , vol.17 , pp. 205-229
    • Lieberman, J.A.1    Sheitman, B.B.2    Kinon, B.J.3
  • 130
    • 0026101940 scopus 로고
    • Effect of the NMDA receptor antagonist, MK-801, on locomotor activity and the metabolism of dopamine in various brain areas of mice
    • Liljequist S., Ossoska K., Grabowska-Anden M., Anden N. Effect of the NMDA receptor antagonist, MK-801, on locomotor activity and the metabolism of dopamine in various brain areas of mice. Eur. J. Pharmacol. 195:1991;55-61.
    • (1991) Eur. J. Pharmacol. , vol.195 , pp. 55-61
    • Liljequist, S.1    Ossoska, K.2    Grabowska-Anden, M.3    Anden, N.4
  • 131
    • 0029122190 scopus 로고
    • Prefrontal cortical and hippocampal modulation of haloperidol-induced catalepsy and apomorphine-induced stereotypic behaviors in the rat
    • Lipska B.K., Jaskiw G.E., Braun A.R., Weinberger D.R. Prefrontal cortical and hippocampal modulation of haloperidol-induced catalepsy and apomorphine-induced stereotypic behaviors in the rat. Biol. Psychiatry. 38:1995;255-262.
    • (1995) Biol. Psychiatry , vol.38 , pp. 255-262
    • Lipska, B.K.1    Jaskiw, G.E.2    Braun, A.R.3    Weinberger, D.R.4
  • 132
    • 0028886663 scopus 로고
    • Neonatal excitotoxic hippocampal damage in rats causes postpubertal changes in prepulse inhibition of startle and its disruption by apomorphine
    • Lipska B.K., Swerdlow N.R., Geyer M.A., Jaskiw G.E., Braff D.L., Weinberger D.R. Neonatal excitotoxic hippocampal damage in rats causes postpubertal changes in prepulse inhibition of startle and its disruption by apomorphine. Psychopharmacology. 122:1995;35-43.
    • (1995) Psychopharmacology , vol.122 , pp. 35-43
    • Lipska, B.K.1    Swerdlow, N.R.2    Geyer, M.A.3    Jaskiw, G.E.4    Braff, D.L.5    Weinberger, D.R.6
  • 133
    • 0002441974 scopus 로고
    • Cortical regulation of the mesolimbic dopamine system: implications for schizophrenia
    • in: P.W. Kalivas, C.D. Barnes (Eds.), CRC Press, Boca Raton, FL
    • B.K. Lipska, D.R. Weinberger, Cortical regulation of the mesolimbic dopamine system: implications for schizophrenia, in: P.W. Kalivas, C.D. Barnes (Eds.), Limbic Motor Circuits and Neuropsychiatry, CRC Press, Boca Raton, FL, 1993, pp. 329-349.
    • (1993) Limbic Motor Circuits and Neuropsychiatry , pp. 329-349
    • Lipska, B.K.1    Weinberger, D.R.2
  • 134
    • 0027429353 scopus 로고
    • Delayed effects of neonatal hippocampal damage on haloperidol-induced catalepsy and apomorphine-induced stereotypic behaviors in the rat
    • Lipska B.K., Weinberger D.R. Delayed effects of neonatal hippocampal damage on haloperidol-induced catalepsy and apomorphine-induced stereotypic behaviors in the rat. Brain Res. 75:1993;213-222.
    • (1993) Brain Res. , vol.75 , pp. 213-222
    • Lipska, B.K.1    Weinberger, D.R.2
  • 135
    • 0345365315 scopus 로고
    • Time to treatment response in successive episodes of early-onset schizophrenia
    • Presented at the International Congress on Schizophrenia Research in Hot Springs, VA, 12 4-8
    • A. Loebel, J. Lieberman, J. Alvir, S. Geisler, A. Koreen, M. Chakos, Time to treatment response in successive episodes of early-onset schizophrenia, Presented at the International Congress on Schizophrenia Research in Hot Springs, VA, 12 4-8, 1995, GENERIC, Ref. Type: Conference Proceeding.
    • (1995) GENERIC, Ref. Type: Conference Proceeding
    • Loebel, A.1    Lieberman, J.2    Alvir, J.3    Geisler, S.4    Koreen, A.5    Chakos, M.6
  • 137
    • 0026579122 scopus 로고
    • The behavioral effects of MK-801 in rats - Involvement of dopaminergic, serotonergic and noradrenergic systems
    • Loscher W., Honack D. The behavioral effects of MK-801 in rats - involvement of dopaminergic, serotonergic and noradrenergic systems. Eur. J. Pharmacol. 214:1992;199-208.
    • (1992) Eur. J. Pharmacol. , vol.214 , pp. 199-208
    • Loscher, W.1    Honack, D.2
  • 140
  • 141
  • 142
    • 0027965557 scopus 로고
    • An overview of family interventions and relapse on schizophrenia - Meta-analysis of research findings
    • Mari J.J., Steiner D.L. An overview of family interventions and relapse on schizophrenia - meta-analysis of research findings. Psychological Medicine. 34:1994;565-578.
    • (1994) Psychological Medicine , vol.34 , pp. 565-578
    • Mari, J.J.1    Steiner, D.L.2
  • 143
    • 0019414614 scopus 로고
    • Schizophrenia - A follow-up study of the results of five forms of treatment
    • May P.R., Tuma A.H., Dixon W.J. Schizophrenia - a follow-up study of the results of five forms of treatment. Arch. Gen. Psychiatry. 38:1981;776-784.
    • (1981) Arch. Gen. Psychiatry , vol.38 , pp. 776-784
    • May, P.R.1    Tuma, A.H.2    Dixon, W.J.3
  • 144
    • 0027936306 scopus 로고
    • The Nithsdale schizophrenia surveys: XIII. Parental rearing patterns, current symptomatology and relatives expressed emotion
    • McCreadie R.G., Williamson D.J., Athawes R.W., Connolly M.A., Tilak-Singh D. The Nithsdale schizophrenia surveys: XIII. Parental rearing patterns, current symptomatology and relatives expressed emotion. Br. J. Psychiatry. 165:1993;347-352.
    • (1993) Br. J. Psychiatry , vol.165 , pp. 347-352
    • McCreadie, R.G.1    Williamson, D.J.2    Athawes, R.W.3    Connolly, M.A.4    Tilak-Singh, D.5
  • 145
    • 0027392835 scopus 로고
    • Subtype progression and pathophysiologic deterioration in early schizophrenia
    • McGlashan T.H., Fenton W.S. Subtype progression and pathophysiologic deterioration in early schizophrenia. Schizophr. Bull. 19:1993;71-84.
    • (1993) Schizophr. Bull. , vol.19 , pp. 71-84
    • McGlashan, T.H.1    Fenton, W.S.2
  • 147
    • 0017079279 scopus 로고
    • The dopamine hypothesis of schizophrenia - A review
    • Meltzer H.Y., Stahl S.M. The dopamine hypothesis of schizophrenia - a review. Schizophr. Bull. 2:1976;19-76.
    • (1976) Schizophr. Bull. , vol.2 , pp. 19-76
    • Meltzer, H.Y.1    Stahl, S.M.2
  • 148
    • 0027231058 scopus 로고
    • Stress preferentially activates extraneuronal levels of excitatory amino acids in the prefrontal cortex a comparison to hippocampus and basal ganglia
    • Moghaddam B. Stress preferentially activates extraneuronal levels of excitatory amino acids in the prefrontal cortex a comparison to hippocampus and basal ganglia. J. Neurochem. 60:1993;1650-1657.
    • (1993) J. Neurochem. , vol.60 , pp. 1650-1657
    • Moghaddam, B.1
  • 149
    • 0030900732 scopus 로고    scopus 로고
    • Activation of glutamatergic neurotransmission by ketamine - A novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex
    • Moghaddam B., Adams B., Verman A., Daly D. Activation of glutamatergic neurotransmission by ketamine - a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex. J. Neurosci. 17:1997;2921-2927.
    • (1997) J. Neurosci. , vol.17 , pp. 2921-2927
    • Moghaddam, B.1    Adams, B.2    Verman, A.3    Daly, D.4
  • 150
    • 0032575715 scopus 로고    scopus 로고
    • Reversal of phencyclidine effects by a group II metabotrophic glutamate receptor agonist in rats
    • Moghaddam B., Adams B.W., Murase S., Mathe J.M., Grenhoff J., Svensson T.H. Reversal of phencyclidine effects by a group II metabotrophic glutamate receptor agonist in rats. Science. 281:1998;1349-1352.
    • (1998) Science , vol.281 , pp. 1349-1352
    • Moghaddam, B.1    Adams, B.W.2    Murase, S.3    Mathe, J.M.4    Grenhoff, J.5    Svensson, T.H.6
  • 151
    • 0027406714 scopus 로고
    • Effects of dizocilpine (MK-801) on rat midbrain dopamine cell activity: Differential action on firing pattern related to anatomical localization
    • Murase S., Mathe J.M., Grenhoff J., Svensson T.H. Effects of dizocilpine (MK-801) on rat midbrain dopamine cell activity: differential action on firing pattern related to anatomical localization. J. Neural Transm. 91:1993;13-25.
    • (1993) J. Neural Transm. , vol.91 , pp. 13-25
    • Murase, S.1    Mathe, J.M.2    Grenhoff, J.3    Svensson, T.H.4
  • 152
    • 0027992744 scopus 로고
    • Neurodevelopmental schizophrenia - The rediscovery of dementia praecox
    • Murray R.M. Neurodevelopmental schizophrenia - the rediscovery of dementia praecox. Br. J. Psychiatry Suppl. 25:1994;6-12.
    • (1994) Br. J. Psychiatry Suppl. , vol.25 , pp. 6-12
    • Murray, R.M.1
  • 153
    • 0026752706 scopus 로고
    • A neurodevelopmental approach to the classification of schizophrenia
    • Murray R.M., O'Callaghan E., Castle D.J., Lewis S.W. A neurodevelopmental approach to the classification of schizophrenia. Schizophr. Bull. 18:1992;319-332.
    • (1992) Schizophr. Bull. , vol.18 , pp. 319-332
    • Murray, R.M.1    O'Callaghan, E.2    Castle, D.J.3    Lewis, S.W.4
  • 156
    • 0018890729 scopus 로고
    • Ketamine-induced changes in regional glucose utilization in the rat brain
    • Nelson S.R., Howard R.B., Cross R.S., Samson F. Ketamine-induced changes in regional glucose utilization in the rat brain. Anesthesiology. 52:1980;330-334.
    • (1980) Anesthesiology , vol.52 , pp. 330-334
    • Nelson, S.R.1    Howard, R.B.2    Cross, R.S.3    Samson, F.4
  • 157
    • 0027396970 scopus 로고
    • Stressful life events and schizophrenia - A review of the research
    • Norman R.M., Malla A.K. Stressful life events and schizophrenia - a review of the research. Br. J. Psychiatry. 162:1993;161-166.
    • (1993) Br. J. Psychiatry , vol.162 , pp. 161-166
    • Norman, R.M.1    Malla, A.K.2
  • 158
    • 0019770981 scopus 로고
    • Amphetamine neurotoxicity on dopamine nerve terminals in the caudate nucleus of mice
    • Nwanze E., Jonsson G. Amphetamine neurotoxicity on dopamine nerve terminals in the caudate nucleus of mice. Neurosci. Lett. 26:1981;163-168.
    • (1981) Neurosci. Lett. , vol.26 , pp. 163-168
    • Nwanze, E.1    Jonsson, G.2
  • 159
    • 0029984110 scopus 로고    scopus 로고
    • Positron emission tomography of in vivo binding characteristics of atypical antipsychotic drugs review of D2 of 5-HT2 receptor occupancy studies and clinical response
    • Nyberg S., Nakashima Y., Nordstrom A.L., Halldin C., Farde L. Positron emission tomography of in vivo binding characteristics of atypical antipsychotic drugs review of D2 of 5-HT2 receptor occupancy studies and clinical response. Br. J. Psychiatry. 168:1996;40-44.
    • (1996) Br. J. Psychiatry , vol.168 , pp. 40-44
    • Nyberg, S.1    Nakashima, Y.2    Nordstrom, A.L.3    Halldin, C.4    Farde, L.5
  • 160
    • 0024399770 scopus 로고
    • Excitatory amino acids and neuropsychiatric disorders
    • Olney J.W. Excitatory amino acids and neuropsychiatric disorders. Biol. Psychiatry. 26:1989;505-525.
    • (1989) Biol. Psychiatry , vol.26 , pp. 505-525
    • Olney, J.W.1
  • 161
    • 0028850552 scopus 로고
    • Glutamate receptor dysfunction and schizophrenia
    • Olney J.W., Farber N.B. Glutamate receptor dysfunction and schizophrenia. Arch. Gen. Psychiatry. 52:1995;998-1007.
    • (1995) Arch. Gen. Psychiatry , vol.52 , pp. 998-1007
    • Olney, J.W.1    Farber, N.B.2
  • 163
    • 0027337246 scopus 로고
    • Effects of dopamine D1 and D2 receptor blockade on MK-801-induced hyperlocomotion in rats
    • Ouagazzal A., Nieoullon A., Amalric M. Effects of dopamine D1 and D2 receptor blockade on MK-801-induced hyperlocomotion in rats. Psychopharmacology. 1:1993;427-434.
    • (1993) Psychopharmacology , vol.1 , pp. 427-434
    • Ouagazzal, A.1    Nieoullon, A.2    Amalric, M.3
  • 164
    • 0028084422 scopus 로고
    • Locomotor activation induced by MK-801 in the rat - Postsynaptic interactions with dopamine receptors in the ventral striatum
    • Ouagazzal A., Nieoullon A., Amalric M. Locomotor activation induced by MK-801 in the rat - postsynaptic interactions with dopamine receptors in the ventral striatum. Eur. J. Pharmacol. 251:1994;229-236.
    • (1994) Eur. J. Pharmacol. , vol.251 , pp. 229-236
    • Ouagazzal, A.1    Nieoullon, A.2    Amalric, M.3
  • 167
    • 0017140214 scopus 로고
    • Cocaine, kindling, and psychosis
    • Post R.M., Kopanda R.T. Cocaine, kindling, and psychosis. Am. J. Psychiatry. 133:1976;627-634.
    • (1976) Am. J. Psychiatry , vol.133 , pp. 627-634
    • Post, R.M.1    Kopanda, R.T.2
  • 168
    • 0022512031 scopus 로고
    • Conditioning and sensitization in the longitudinal course of affective illness
    • Post R.M., Rubinow D.R., Ballenger J.C. Conditioning and sensitization in the longitudinal course of affective illness. Br. J. Psychiatry. 149:1986;191-201.
    • (1986) Br. J. Psychiatry , vol.149 , pp. 191-201
    • Post, R.M.1    Rubinow, D.R.2    Ballenger, J.C.3
  • 169
    • 0018903573 scopus 로고
    • Effect of 6-hyroxydopamine lesions of the medial prefrontal cortex on neurotransmitter systems in subcortical sites in the rat
    • Pycock C.J., Carter C.J., Kerwin R.W. Effect of 6-hyroxydopamine lesions of the medial prefrontal cortex on neurotransmitter systems in subcortical sites in the rat. J. Neurochem. 34:1980;91-99.
    • (1980) J. Neurochem. , vol.34 , pp. 91-99
    • Pycock, C.J.1    Carter, C.J.2    Kerwin, R.W.3
  • 170
    • 0032498817 scopus 로고    scopus 로고
    • Neuronal and glial somal size in the prefrontal cortex - A postmortem morphometric study of schizophrenia and Huntington disease
    • Rajkowska G., Selemon L.D., Goldman-Rakic P.S. Neuronal and glial somal size in the prefrontal cortex - a postmortem morphometric study of schizophrenia and Huntington disease. Arch. Gen. Psychiatry. 55:1998;215-224.
    • (1998) Arch. Gen. Psychiatry , vol.55 , pp. 215-224
    • Rajkowska, G.1    Selemon, L.D.2    Goldman-Rakic, P.S.3
  • 171
    • 0024517165 scopus 로고
    • Ketamine - An update on the first twenty years of clinical experience
    • Reich D.L., Silvay G. Ketamine - an update on the first twenty years of clinical experience. Can. J. Anaesth. 36:1989;186-197.
    • (1989) Can. J. Anaesth. , vol.36 , pp. 186-197
    • Reich, D.L.1    Silvay, G.2
  • 172
    • 0022725590 scopus 로고
    • Enduring changes in brain and behavior produced by chronic amphetamine administration - A review and evaluation of animal models of amphetamine psychosis
    • Robinson T.E., Becker J.B. Enduring changes in brain and behavior produced by chronic amphetamine administration - a review and evaluation of animal models of amphetamine psychosis. Brain Res. Rev. 11:1986;157-198.
    • (1986) Brain Res. Rev. , vol.11 , pp. 157-198
    • Robinson, T.E.1    Becker, J.B.2
  • 174
    • 0025290982 scopus 로고
    • Histological and ultrastructural evidence that D-amphetamine causes degeneration in neostriatum and frontal cortex of rates
    • Ryan L., Martone M., Linder J., Groves P. Histological and ultrastructural evidence that D-amphetamine causes degeneration in neostriatum and frontal cortex of rates. Brain Res. 518:1990;67-77.
    • (1990) Brain Res. , vol.518 , pp. 67-77
    • Ryan, L.1    Martone, M.2    Linder, J.3    Groves, P.4
  • 175
    • 0026539045 scopus 로고
    • Relapse of paranoid psychotic state in methamphetamine model of schizophrenia
    • Sato M., Numachi Y., Hamamura T. Relapse of paranoid psychotic state in methamphetamine model of schizophrenia. Schizophr. Bull. 18:1992;115-122.
    • (1992) Schizophr. Bull. , vol.18 , pp. 115-122
    • Sato, M.1    Numachi, Y.2    Hamamura, T.3
  • 176
    • 0030438479 scopus 로고    scopus 로고
    • Regional effects of MK-801 on dopamine release effects of competitive NMDA or 5-HT2A receptor blocade
    • Schmidt C.J., Fadayel G.M. Regional effects of MK-801 on dopamine release effects of competitive NMDA or 5-HT2A receptor blocade. J. Pharmacol. Exp. Ther. 277:1996;1541-1549.
    • (1996) J. Pharmacol. Exp. Ther. , vol.277 , pp. 1541-1549
    • Schmidt, C.J.1    Fadayel, G.M.2
  • 177
    • 0023254675 scopus 로고
    • Dopamine receptors and the dopamine hypothesis of schizophrenia
    • Seeman P. Dopamine receptors and the dopamine hypothesis of schizophrenia. Synapse. 1:1987;133-152.
    • (1987) Synapse , vol.1 , pp. 133-152
    • Seeman, P.1
  • 178
    • 0017068246 scopus 로고
    • Antipsychotic drug doses and neuroleptic/dopamine receptors
    • Seeman P., Lee T., Chau-Wong M., Wong K. Antipsychotic drug doses and neuroleptic/dopamine receptors. Nature. 261:1976;717-719.
    • (1976) Nature , vol.261 , pp. 717-719
    • Seeman, P.1    Lee, T.2    Chau-Wong, M.3    Wong, K.4
  • 180
    • 0029038731 scopus 로고
    • Does dizocilpine (MK-801) selectively block the enhanced responsiveness to repeated amphetamine administration?
    • Segal D.S., Kuczenski R., Florin S.M. Does dizocilpine (MK-801) selectively block the enhanced responsiveness to repeated amphetamine administration? Behavioral Neuroscience. 109:1995;532-546.
    • (1995) Behavioral Neuroscience , vol.109 , pp. 532-546
    • Segal, D.S.1    Kuczenski, R.2    Florin, S.M.3
  • 181
    • 0027305582 scopus 로고
    • Cortical-striatal-thalamic circuits and brain glucose metabolic activity in 70 unmedicated male schizophrenic patients
    • Siegel B.V., Buchsbaum B.S., Bunney W.E. Cortical-striatal-thalamic circuits and brain glucose metabolic activity in 70 unmedicated male schizophrenic patients. Am. J. Psychiatry. 150:1993;1325-1356.
    • (1993) Am. J. Psychiatry , vol.150 , pp. 1325-1356
    • Siegel, B.V.1    Buchsbaum, B.S.2    Bunney, W.E.3
  • 182
    • 0018386391 scopus 로고
    • Neuronal responses to ketamine administered microiontophoretically or intraperitoneally in the rat
    • Sinclair J.G., Tien A.F. Neuronal responses to ketamine administered microiontophoretically or intraperitoneally in the rat. Gen. Pharmacol. 10:1979;51-55.
    • (1979) Gen. Pharmacol. , vol.10 , pp. 51-55
    • Sinclair, J.G.1    Tien, A.F.2
  • 183
    • 0019505743 scopus 로고
    • Properties of the optical isomers and metabolites of ketamine on the high affinity transport and catabolism of monoamines
    • Smith D.J., Azzaro A.J., Zaldivar S.B., Palmer S., Lee H.S. Properties of the optical isomers and metabolites of ketamine on the high affinity transport and catabolism of monoamines. Neuropharmacology. 120:1981;391-396.
    • (1981) Neuropharmacology , vol.120 , pp. 391-396
    • Smith, D.J.1    Azzaro, A.J.2    Zaldivar, S.B.3    Palmer, S.4    Lee, H.S.5
  • 184
    • 0019224563 scopus 로고
    • The interaction of ketamine with the opiate receptor
    • Smith D.J., Pekoe G.M., Martin L.L., Coalgate B. The interaction of ketamine with the opiate receptor. Life Sci. 26:1980;789-795.
    • (1980) Life Sci. , vol.26 , pp. 789-795
    • Smith, D.J.1    Pekoe, G.M.2    Martin, L.L.3    Coalgate, B.4
  • 187
    • 0027340265 scopus 로고
    • Effects of cocaine and footshock stress on extracellular dopamine levels in the medial prefrontal cortex
    • Sorg B.A., Kalivas P.W. Effects of cocaine and footshock stress on extracellular dopamine levels in the medial prefrontal cortex. Neuroscience. 53:1993;695-703.
    • (1993) Neuroscience , vol.53 , pp. 695-703
    • Sorg, B.A.1    Kalivas, P.W.2
  • 188
    • 0024436036 scopus 로고
    • Electrophysiological effects of selective sigma-receptor agonists, antagonists, and the selective phencyclidine receptor agonist MK-801 on midbrain dopamine neurons
    • Steinfels G.F., Tam S.W., Cook L. Electrophysiological effects of selective sigma-receptor agonists, antagonists, and the selective phencyclidine receptor agonist MK-801 on midbrain dopamine neurons. Neuropsychopharmacology. 2:1989;201-208.
    • (1989) Neuropsychopharmacology , vol.2 , pp. 201-208
    • Steinfels, G.F.1    Tam, S.W.2    Cook, L.3
  • 189
    • 0030297729 scopus 로고    scopus 로고
    • Enhanced response to repeated D-amphetamine challenge: Evidence for behavioral sensitization in humans
    • Strakowski S.M., Sax K.W., Setters M.J., Keck P.E. Jr. Enhanced response to repeated D-amphetamine challenge: evidence for behavioral sensitization in humans. Biol. Psychiatry. 40:1996;872-880.
    • (1996) Biol. Psychiatry , vol.40 , pp. 872-880
    • Strakowski, S.M.1    Sax, K.W.2    Setters, M.J.3    Keck P.E., Jr.4
  • 190
    • 0026496482 scopus 로고
    • Schizophrenia after prenatal exposure to the Dutch hunger winter of 1944-1945
    • Susser E.S., Lin E.P. Schizophrenia after prenatal exposure to the Dutch hunger winter of 1944-1945. Arch. Gen. Psychiatry. 49:1992;983-988.
    • (1992) Arch. Gen. Psychiatry , vol.49 , pp. 983-988
    • Susser, E.S.1    Lin, E.P.2
  • 191
    • 0030426257 scopus 로고    scopus 로고
    • Seroquel restores sensorimotor gating in phencyclidine-treated rats
    • Swerdlow N.R., Bakshi V., Geyer M.A. Seroquel restores sensorimotor gating in phencyclidine-treated rats. J. Pharmacol. Exp. Ther. 279:1996;1290-1299.
    • (1996) J. Pharmacol. Exp. Ther. , vol.279 , pp. 1290-1299
    • Swerdlow, N.R.1    Bakshi, V.2    Geyer, M.A.3
  • 193
    • 0021991451 scopus 로고
    • An N-methyl-aspartate receptor-mediated synapse in rat cerebral cortex: A site of action of ketamine?
    • Thomson A.M., West D.C., Lodge D. An N-methyl-aspartate receptor-mediated synapse in rat cerebral cortex: a site of action of ketamine? Nature. 313:1985;479-481.
    • (1985) Nature , vol.313 , pp. 479-481
    • Thomson, A.M.1    West, D.C.2    Lodge, D.3
  • 194
    • 0025334698 scopus 로고
    • MK-801-induced stereotypy and its antagonism by neuroleptic drugs
    • Tiedtke P.I., Bischoff C., Schmidt W.J. MK-801-induced stereotypy and its antagonism by neuroleptic drugs. J. Neural Transm. 81:1990;173-182.
    • (1990) J. Neural Transm. , vol.81 , pp. 173-182
    • Tiedtke, P.I.1    Bischoff, C.2    Schmidt, W.J.3
  • 195
    • 0029739587 scopus 로고    scopus 로고
    • Evidence for dissociable mechanisms of amphetamine- And stress-induced behavioral sensitization - Effects of MK-801 and haloperidol pretreatment
    • Tolliver B.K., Ho L.B., Reid M.S., Berger S.P. Evidence for dissociable mechanisms of amphetamine- and stress-induced behavioral sensitization - effects of MK-801 and haloperidol pretreatment. Psychopharmacology. 126:1996;191-198.
    • (1996) Psychopharmacology , vol.126 , pp. 191-198
    • Tolliver, B.K.1    Ho, L.B.2    Reid, M.S.3    Berger, S.P.4
  • 196
    • 0025924374 scopus 로고
    • A viral-anatomical explanation of schizophrenia
    • Torrey E.F. A viral-anatomical explanation of schizophrenia. Schizophr. Bull. 17:1991;15-18.
    • (1991) Schizophr. Bull. , vol.17 , pp. 15-18
    • Torrey, E.F.1
  • 197
    • 0032403626 scopus 로고    scopus 로고
    • D-serine added to antipsychotics for the treatment of schizophrenia
    • Tsai G., Pinchen Y., Chung L.-C., Lange N., Coyle J.T. D-serine added to antipsychotics for the treatment of schizophrenia. Biol. Psychiatry. 44:1998;1081-1089.
    • (1998) Biol. Psychiatry , vol.44 , pp. 1081-1089
    • Tsai, G.1    Pinchen, Y.2    Chung, L.-C.3    Lange, N.4    Coyle, J.T.5
  • 199
    • 0026034858 scopus 로고
    • The genetics of schizophrenia - Current knowledge and future directions
    • Tsuang M.T., Gilbertson M.W., Faroane S.V. The genetics of schizophrenia - current knowledge and future directions. Schizophr. Res. 4:1991;157-171.
    • (1991) Schizophr. Res. , vol.4 , pp. 157-171
    • Tsuang, M.T.1    Gilbertson, M.W.2    Faroane, S.V.3
  • 200
    • 0025174987 scopus 로고
    • Heterogeneity of schizophrenia - Conceptual models and analytic strategies
    • Tsuang M.T., Lyons M.J., Faraone S.V. Heterogeneity of schizophrenia - conceptual models and analytic strategies. Br. J. Psychiatry. 156:1990;17-26.
    • (1990) Br. J. Psychiatry , vol.156 , pp. 17-26
    • Tsuang, M.T.1    Lyons, M.J.2    Faraone, S.V.3
  • 201
    • 0031727629 scopus 로고    scopus 로고
    • Does the non-competitive NMDA receptor antagonist dizocilpine (MK-801) really block behavioral sensitization associated with repeated drug administration?
    • Tzschentke T.M., Schmidt W.J. Does the non-competitive NMDA receptor antagonist dizocilpine (MK-801) really block behavioral sensitization associated with repeated drug administration? Trends Pharmacol. Sci. 19:1998;447-451.
    • (1998) Trends Pharmacol. Sci. , vol.19 , pp. 447-451
    • Tzschentke, T.M.1    Schmidt, W.J.2
  • 202
    • 0030034191 scopus 로고    scopus 로고
    • NMDA receptor antagonists impair prefrontal cortex function as assessed via spatial delayed alternation performance in rats modulation by dopamine
    • Verma A., Moghaddam B. NMDA receptor antagonists impair prefrontal cortex function as assessed via spatial delayed alternation performance in rats modulation by dopamine. J. Neurosci. 16:1996;373-379.
    • (1996) J. Neurosci. , vol.16 , pp. 373-379
    • Verma, A.1    Moghaddam, B.2
  • 205
    • 0015598446 scopus 로고
    • Involvement of nigrostriatal neurons in the in vivo release of dopamine by amphetamine, amantadine, and tyramine
    • Von Voightlander P.F.M. Involvement of nigrostriatal neurons in the in vivo release of dopamine by amphetamine, amantadine, and tyramine. J. Pharmacol. Exp. Ther. 184:1971;542-552.
    • (1971) J. Pharmacol. Exp. Ther. , vol.184 , pp. 542-552
    • Von Voightlander, P.F.M.1
  • 206
    • 0031953485 scopus 로고    scopus 로고
    • Neurodevelopmental and neuroprogressive processes in schizophrenia: Antithetical or complementary, over a lifetime trajectory of disease? (review)
    • 194 Refs.
    • Waddington J.L., Lane A., Scully P.J., Larkin C., O'Callaghan E. Neurodevelopmental and neuroprogressive processes in schizophrenia: antithetical or complementary, over a lifetime trajectory of disease? (review). Psychiatr. Clin. North Am. 21:1998;123-149. 194 Refs.
    • (1998) Psychiatr. Clin. North Am. , vol.21 , pp. 123-149
    • Waddington, J.L.1    Lane, A.2    Scully, P.J.3    Larkin, C.4    O'Callaghan, E.5
  • 207
    • 0026042068 scopus 로고
    • Twin studies of psychopathology - Why do the concordance rates vary?
    • Walker E., Downey G., Caspi A. Twin studies of psychopathology - why do the concordance rates vary? Schizophr. Res. 1:1991;211-221.
    • (1991) Schizophr. Res. , vol.1 , pp. 211-221
    • Walker, E.1    Downey, G.2    Caspi, A.3
  • 208
    • 0025003904 scopus 로고
    • Prediction of adult-onset schizophrenia from childhood home movies of the patients
    • Walker E., Lewine R.J. Prediction of adult-onset schizophrenia from childhood home movies of the patients. Am. J. Psychiatry. 147:1990;1052-1056.
    • (1990) Am. J. Psychiatry , vol.147 , pp. 1052-1056
    • Walker, E.1    Lewine, R.J.2
  • 209
    • 0031800006 scopus 로고    scopus 로고
    • M100907 and clozapine, but not haloperidol or raclopride, prevent phencyclidine-induced blockade of NMDA responses in pyramidal neurons of the rat medial prefrontal cortical slice
    • Wang R.Y., Liang X. M100907 and clozapine, but not haloperidol or raclopride, prevent phencyclidine-induced blockade of NMDA responses in pyramidal neurons of the rat medial prefrontal cortical slice. Neuropsychopharmacology. 19:1998;74-85.
    • (1998) Neuropsychopharmacology , vol.19 , pp. 74-85
    • Wang, R.Y.1    Liang, X.2
  • 210
    • 0018253837 scopus 로고
    • Patterns of childhood social development in adult schizophrenics
    • Watt N.F. Patterns of childhood social development in adult schizophrenics. Arch. Gen. Psychiatry. 35:1978;160-165.
    • (1978) Arch. Gen. Psychiatry , vol.35 , pp. 160-165
    • Watt, N.F.1
  • 211
    • 0027244379 scopus 로고
    • MK-801 elevates the extracellular concentration of dopamine in the rat prefrontal cortex and increases the density of striatal dopamine D1 receptors
    • Wedzony K., Klimek V., Golembiowska K. MK-801 elevates the extracellular concentration of dopamine in the rat prefrontal cortex and increases the density of striatal dopamine D1 receptors. Brain Res. 622:1993;325-329.
    • (1993) Brain Res. , vol.622 , pp. 325-329
    • Wedzony, K.1    Klimek, V.2    Golembiowska, K.3
  • 212
    • 0021747963 scopus 로고
    • Computed tomography (CT) findings in schizophrenia - Speculation on the meaning of it all
    • Weinberger D.R. Computed tomography (CT) findings in schizophrenia - speculation on the meaning of it all. J. Psychiatr. Res. 18:1984;477-490.
    • (1984) J. Psychiatr. Res. , vol.18 , pp. 477-490
    • Weinberger, D.R.1
  • 213
    • 0023215296 scopus 로고
    • Implications of normal brain development for the pathogenesis of schizophrenia
    • Weinberger D.R. Implications of normal brain development for the pathogenesis of schizophrenia. Arch. Gen. Psychiatry. 44:1987;660-669.
    • (1987) Arch. Gen. Psychiatry , vol.44 , pp. 660-669
    • Weinberger, D.R.1
  • 214
    • 0023918477 scopus 로고
    • Physiologic dysfunction of the prefrontal cortex in schizophrenia - A new cohort and evidence of a monoaminergic mechanism
    • Weinberger D.R., Berman K.F., Illowsky B.P. Physiologic dysfunction of the prefrontal cortex in schizophrenia - a new cohort and evidence of a monoaminergic mechanism. Arch. Gen. Psychiatry. 45:1988;609-615.
    • (1988) Arch. Gen. Psychiatry , vol.45 , pp. 609-615
    • Weinberger, D.R.1    Berman, K.F.2    Illowsky, B.P.3
  • 215
    • 0020637803 scopus 로고
    • Differential effects of classical and atypical antipsychotic drugs on A9 and A10 dopamine neurons
    • White F.J., Wang R.Y. Differential effects of classical and atypical antipsychotic drugs on A9 and A10 dopamine neurons. Science. 221:1983;1054-1057.
    • (1983) Science , vol.221 , pp. 1054-1057
    • White, F.J.1    Wang, R.Y.2
  • 216
    • 0020037594 scopus 로고
    • Ketamine - Its pharmacology and therapeutic uses
    • White P.F., Way W.L., Trevor A.J. Ketamine - its pharmacology and therapeutic uses. Anesthesiology. 56:1982;119-136.
    • (1982) Anesthesiology , vol.56 , pp. 119-136
    • White, P.F.1    Way, W.L.2    Trevor, A.J.3
  • 217
    • 0027527037 scopus 로고
    • The role of dopamine and AMPA/kainate receptors in the nucleus accumbens in the hypermotility response to MK801
    • Willins D.L., Narayanan S., Wallace L.J., Uretsky N.J. The role of dopamine and AMPA/kainate receptors in the nucleus accumbens in the hypermotility response to MK801. Pharmacol. Biochem. Behav. 46:1993;881-887.
    • (1993) Pharmacol. Biochem. Behav. , vol.46 , pp. 881-887
    • Willins, D.L.1    Narayanan, S.2    Wallace, L.J.3    Uretsky, N.J.4
  • 218
    • 0015341344 scopus 로고
    • The cataleptic state induced by ketamine - A review of the neuropharmacology of anesthesia
    • Winters W.D., Ferrer-Allado T., Guzman-Flores C., Alcaraz M. The cataleptic state induced by ketamine - a review of the neuropharmacology of anesthesia. Neuropharmacology. 11:1972;303-315.
    • (1972) Neuropharmacology , vol.11 , pp. 303-315
    • Winters, W.D.1    Ferrer-Allado, T.2    Guzman-Flores, C.3    Alcaraz, M.4
  • 219
    • 0029935239 scopus 로고    scopus 로고
    • MK-801 (dizocilpine) synergist and conditioned stimulus in bromocriptine-induced psychomotor sensitization
    • Wise R.A., Mendrek A., Carlezon W.A.J. MK-801 (dizocilpine) synergist and conditioned stimulus in bromocriptine-induced psychomotor sensitization. Synapse. 22:1996;362-368.
    • (1996) Synapse , vol.22 , pp. 362-368
    • Wise, R.A.1    Mendrek, A.2    Carlezon, W.A.J.3
  • 220
    • 0031908310 scopus 로고    scopus 로고
    • The role of excitatory amino acids in behavioral sensitization to psychomotor stimulants
    • Wolf M.E. The role of excitatory amino acids in behavioral sensitization to psychomotor stimulants. Progress in Neurobiology. 54:1998;679-720.
    • (1998) Progress in Neurobiology , vol.54 , pp. 679-720
    • Wolf, M.E.1
  • 221
    • 0027182393 scopus 로고
    • Behavioral sensitization to MK-801 (dizocilpine) - Neurochemical and electrophysiological correlates in the mesoaccumbens dopamine system
    • Wolf M.E., White F.J., Hu X.T. Behavioral sensitization to MK-801 (dizocilpine) - neurochemical and electrophysiological correlates in the mesoaccumbens dopamine system. Behav. Pharmacol. 4:1993;429-442.
    • (1993) Behav. Pharmacol. , vol.4 , pp. 429-442
    • Wolf, M.E.1    White, F.J.2    Hu, X.T.3
  • 222
    • 0030815517 scopus 로고    scopus 로고
    • Behavioral changes in rats with early ventral hippocampal damage vary with age at damage
    • Wood G.K., Lipska B.K., Weinberger D.R. Behavioral changes in rats with early ventral hippocampal damage vary with age at damage. Brain Res. 101:1997;17-25.
    • (1997) Brain Res. , vol.101 , pp. 17-25
    • Wood, G.K.1    Lipska, B.K.2    Weinberger, D.R.3
  • 223
    • 0026040246 scopus 로고
    • Neuroleptics and the natural course of schizophrenia
    • Wyatt R.J. Neuroleptics and the natural course of schizophrenia. Schizophr. Bull. 17:1991;325-351.
    • (1991) Schizophr. Bull. , vol.17 , pp. 325-351
    • Wyatt, R.J.1
  • 224
    • 0029339575 scopus 로고
    • Early intervention for schizophrenia - Can the course of the illness be altered
    • Wyatt R.J. Early intervention for schizophrenia - can the course of the illness be altered. Biol. Psychiatry. 38:1995;1-3.
    • (1995) Biol. Psychiatry , vol.38 , pp. 1-3
    • Wyatt, R.J.1


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