A murine model for human cord blood transplantation: Near-term fetal and neonatal peripheral blood cells can achieve long-term bone marrow engraftment in sublethally irradiated adult recipients

Blood

Volumn 89, Issue 3, 1997, Pages 1089-1099

  Scaradavou, Andromachi ^b   Isola, Luis ^b   Rubinstein, Pablo ^b   Galperin, Yelena ^b   Najfeld, Vesna ^b   Berlin, David ^b   Gordon, Jon ^b   Weinberg, Rona S ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

HEMOPOIETIC GROWTH FACTOR; RECOMBINANT INTERLEUKIN 3; RECOMBINANT INTERLEUKIN 6; RECOMBINANT STEM CELL FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW TRANSPLANTATION; CHIMERA; CONTROLLED STUDY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE THERAPY; HEMATOPOIETIC CELL; IRRADIATION; ISOGRAFT; MONONUCLEAR CELL; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TRANSGENE; UMBILICAL CORD BLOOD;

EID: 0030952234     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v89.3.1089     Document Type: Article

References (38)

1. Broxmeyer HE, Douglas GW, Hangoc C, Cooper S, Bard J, English D, Arny M, Thomas L, Boyse EA: Human umbilical cord blood as a potential source of transplantable hematopoietic stem/ progenitor cells. Proc Natl Acad Sci USA 86:3828, 1989
2. Wagner JE, Kernan NA, Broxmeyer HE, Gluckman E: Transplantation of umbilical cord blood in 50 patients: Analysis of the Registry data. Blood 84:395a, 1994 (abstr, suppl 1)
3. Kurtzberg J, Graham M, Casey J, Olson J, Stevens C, Rubinstein P: The use of umbilical cord blood in mismatched related and unrelated hemopoietic stem cell transplantation. Blood Cells 20:275, 1994
4. Kurtzberg J, Laughlin M, Smith C, Olsen J, Graham ML, Stevens C, Rubinstein P: Umbilical cord blood: An alternative source of hematopoietic stem cells for bone marrow reconstitution in unrelated donor transplantation. Blood 86:290a, 1995 (abstr, suppl 1)
5. Rubinstein P, Rosenfield RE, Adamson JW, Stevens CE: Stored placental blood for unrelated bone marrow reconstitution. Blood 81:1679, 1993
6. Rubinstein P, Taylor PE, Scaradavou A, Adamson JW, Migliaccio G, Emmanuel D, Berkowitz RL, Alvarez E, Stevens CE: Unrelated placental blood for bone marrow reconstitution: Organization of the Placental Blood Project. Blood Cells 20:587, 1994
7. 3+ hematopoietic stem/progenitor cells for human umbilical cord blood. J Exp Med 178:2089, 1988
8. Iscove NM, Sieber F, Winterhalter KH: Erythroid colony formation in cultures of mouse and human bone marrow: Analysis of the requirement for erythropoietin by gel filtration and affinity chromatography on agarose-conconavalin A. J Cell Physiol 83:309, 1974
9. McLeod DL, Shreive MM, Axelrad AA: Improved plasma culture system for production of erythrocytic colonies in vitro: Quantative assay method for CFU-E. Blood 44:515, 1974
10. Muench MO, Moore MAS: Accelerated recovery of peripheral blood cell counts in mice transplanted with in vitro cytokine-expanded hematopoietic progenitors. Exp Hematol 20:611, 1992
11. Muench MO, Firpo MT, Moore MAS: Bone marrow transplantation with interleukin-1 plus kit-ligand ex vivo expanded bone marrow accelerates hematopoietic reconstitution in mice without the loss of stem cell lineage and proliferative potential. Blood 81:3463, 1993
12. Roninson IB, Chin JE, Choi K, Gros P, Housman DE, Fojo A, Shen D-W, Gottesman MM, Pastan I: Isolation of human mdr DNA sequences amplified in multidrug resistant KB carcinoma cells. Proc Natl Acad Sci USA 83:4538, 1986
13. Isola L, Frank S, Cagnoni P, Gordon J: Cardiotoxicity of adriamycin in multidrug resistant mice. Blood 80:1744a, 1992 (abstr)
14. Gordon JW, Scangos GA, Plotkin DJ, Barbosa JA, Ruddle FH: Genetic transformation of mouse embryos by microinjection of purified DNA. Proc Natl Acad Sci USA 77:7380, 1980
15. Weinberg RS, Thomson JC, Lao R, Chen G, Alter BP: Stem cell factor amplifies newborn and sickle erythropoiesis in liquid cultures. Blood 81:2591, 1993
16. Weinberg RS, Golberg JD, Scofild JM, Lenes AL, Styczynski R, Alter BP: Switch from fetal to adult hemoglobin is associated with a change in progenitor cell population. J Clin Invest 7:785, 1983
17. Noonan KE, Beck C, Holtmayer TA, Chin JE, Wunder JS, Andrulis IL, Gadzar AF, William CL, Griffith B, Von Hoff DD, Roninson IB: Quantative analysis of MDRI (multidrug resistance) gene expression in human tumors by polymerase chain reaction. Proc Natl Acad Sci USA 87:7160, 1990
18. Bradbury M, Isola L, Gordon J: Enzymatic amplification of a repeated DNA sequence from the mouse Y chromosome allows the determination of sex in a single blastomere. Proc Natl Acad Sci USA 87:4053, 1990
19. Najfeld V, Ballard SG, Menninger J, Ward DC, Bouhassira EE, Schwartz RS, Nagel RL, Rybicki AC: The gene for human erythrocyte protein 4.2 maps to chromosome 15q15. Am J Hum Genet 50:71, 1992
20. Najfeld V, Menninger J, Ballard SG, Dequchi Y, Ward DC, Kehrl JH: Two diverged human homeobox genes involved in the differentiation of human hematopoietic progenitors map to chromosome 1q41-q42.1. Genes Chromosom Cancer 5:343, 1992
21. Broxmeyer HE, Kurtzberg J, Gluckman E, Auerbach AD, Douglas G, Cooper S, Falkenburg JHF, Bard J, Boyse EA: Umbilical cord blood hematopoietic stem and repopulating cells in human clinical transplantation. Blood Cells 17:313, 1991
22. La Salle V, Gluckman E, Bruley-Rosset M: Newborn blood can engraft adult mice without inducing graft-versus-host disease across non-H2 antigens. Blood 87:3977, 1996
23. Barker JE: Embryonic mouse peripheral blood colony-forming units. Nature 228:1305, 1970
24. Carow CE, Hangoc G, Broxmeyer HE: Human multipotential progenitor cells (CFU-GEMM) have extensive replating capacity for secondary CFU-GEMM: An effect enhanced by cord blood plasma. Blood 81:942, 1993
25. Lu L, Xiao M, Shen R-N, Grigsby S, Broxmeyer HE: Enrichment, characterization and responsiveness of single primitive CD34+ human umbilical cord blood hematopoietic progenitors with high proliferative and replating potential. Blood 81:41, 1993
26. Muench M, Schneider JG, Moore MAS: Interactions among colony stimulating factors, IL-1b, IL-6 and kit-ligand in the regulation of primitive murine hematopoietic cells. Exp Hematol 20:339, 1992
27. Moore MAS, Hoskin I: Ex vivo expansion of cord blood-derived stem cells and progenitors. Blood Cells 20:468, 1994
28. Migliaccio AR, Migliaccio G, Adamson JW: Expansion of human neonatal progenitor cells in vitro under serum-deprived conditions. Blood Cells 20:424, 1994
29. Van Epps DE, Bendin J, Lee W, Schilling W, Smith A, Smith S, Unverzagt K, Law P, Burgers J: Harvesting, characterization and culture of CD34+ cells from human bone marrow, peripheral blood and cord blood. Blood Cells 20:411, 1994
30. Ruggieri L, Heimfeld S, Broxmeyer HE: Cytokine-dependent ex vivo expansion of early subsets of CD34+ cord blood myeloid progenitors is enhanced by cord blood plasma, but expansion of more mature subsets of progenitors is favored. Blood Cells 20:436, 1994
31. Peters SO, Kittler ELW, Ramshaw HS, Quesenberry PJ: Ex vivo expansion of murine marrow cells with interleukin-3 (IL-3), IL-6, IL-11 and stem cell factor leads to impaired engraftment in irradiated hosts. Blood 87:30, 1996
32. Blaese RM: Development of gene therapy for immunodeficiency: Adenosine deaminase deficiency. Pediatr Res 33:S42, 1993 (suppl 1)
33. Moritz T, Keller DC, Williams DA: Human cord blood cells as targets for gene transfer: Potential use in genetic therapies of severe combined immunodeficiency disease. J Exp Med 178:529, 1993
34. Harrison DE: Competitive repopulation in unirradiated normal recipients. Blood 81:2473, 1993
35. Stewart FM, Crittenden RB, Lowry PA, Pearson-White S, Quesenberry PJ: Long-term engraftment of normal and post 5-fluorouracil murine marrow into normal nonmyeloablated mice. Blood 81:2566, 1993
36. Barker JE, Compton ST: Hematopoietic repopulation of adult mice with β-thalassemia. Blood 83:828, 1994
37. Blau CA, Stamatoyannopoulos G: Preemptive therapy for genetic disease. Nature Medicine 2:161, 1996
38. Luskey BD, Rosenblatt M, Zsebo K, Williams DA: Stem cell factor, IL-3 and IL-6 promote retroviral-mediated gene transfer into murine hematopoietic stem cells. Blood 80:396, 1992