Site-directed mutagenesis of dendrotoxin K reveals amino acids critical for its interaction with neuronal K+ channels

Biochemistry

Volumn 36, Issue 25, 1997, Pages 7690-7696

  Smith, Leonard A ^a   Reid, Paul F ^a   Wang, Fan C ^b   Parcej, David N ^b   Schmidt, James J ^a   Olson, Mark A ^a   Dolly, J Oliver ^b  

^a UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; DENDROTOXIN; MUTANT PROTEIN; POTASSIUM CHANNEL; POTASSIUM ION; VENOM;

ARTICLE; ESCHERICHIA COLI; NEUROTOXICITY; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN ISOLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; TOXIN STRUCTURE;

ANIMALS; ELAPID VENOMS; MUTAGENESIS, SITE-DIRECTED; NEURONS; PEPTIDES; POTASSIUM CHANNELS; PROTEIN BINDING; RATS; RECOMBINANT PROTEINS;

CROCODYLUS NILOTICUS; ESCHERICHIA COLI;

EID: 0030872270     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi963105g     Document Type: Article

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