An evolutionarily conserved binding site for serine proteinase inhibitors in large conductance calcium-activated potassium channels

Biochemistry

Volumn 35, Issue 50, 1996, Pages 16024-16035

  Moss, Guy W J ^a   Marshall, John ^a,b   Morabito, Maria ^a   Howe, James R ^a   Moczydlowski, Edward ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BOVINAE; GALLUS GALLUS; MAMMALIA;

APROTININ; COMPLEMENTARY DNA; POTASSIUM CHANNEL; PROTEIN SUBUNIT; SERINE PROTEINASE INHIBITOR; CALCIUM ACTIVATED POTASSIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; DROSOPHILA PROTEIN; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL ALPHA SUBUNIT; OVOINHIBITOR; RECOMBINANT PROTEIN; SLO PROTEIN, DROSOPHILA;

ALPHA CHAIN; ANIMAL CELL; AORTA MEDIA; ARTICLE; BINDING SITE; CATTLE; CELL LINE; CONTROLLED STUDY; DISSOCIATION; HUMAN; HUMAN CELL; MOLECULAR CLONING; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN TERTIARY STRUCTURE; SMOOTH MUSCLE FIBER; AMINO ACID SEQUENCE; ANIMAL; AUDIOVISUAL EQUIPMENT; BINDING COMPETITION; CELL MEMBRANE POTENTIAL; CHEMISTRY; CHICKEN; COMPARATIVE STUDY; DROSOPHILA; DRUG EFFECT; GENETIC TRANSFECTION; KIDNEY; KINETICS; MAMMAL; METABOLISM; MOLECULAR EVOLUTION; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROTEIN INTAKE; PROTEIN SECONDARY STRUCTURE; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; APROTININ; BINDING SITES; BINDING, COMPETITIVE; CALCIUM CHANNEL BLOCKERS; CATTLE; CELL LINE; CHICKENS; CLONING, MOLECULAR; CONSERVED SEQUENCE; DROSOPHILA; DROSOPHILA PROTEINS; EGG PROTEINS, DIETARY; EVOLUTION, MOLECULAR; HUMANS; KIDNEY; KINETICS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA SUBUNITS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MAMMALS; MEMBRANE POTENTIALS; MODELS, STRUCTURAL; MOLECULAR SEQUENCE DATA; POTASSIUM CHANNELS; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SERINE PROTEINASE INHIBITORS; TRANSFECTION;

EID: 0030299989     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi961452k     Document Type: Article

References (58)

1. Adelman, J. P., Shen, K.-Z., Kavanaugh, M. P., Warren R. A., Wu., Y.-N., Lagrutta, A., Bond, C. T., & North, A. R. (1992) Neuron 9, 209-216.
2. Antonini, E., Ascenzi, P., Bolognesi, M., Gatti, G., Guarneri, M., & Menegatti, E. (1983) J. Mol. Biol. 165, 543-558.
3. Atkinson, N. S., Robertson, G. A., & Ganetzky, B. (1991) Science 253, 551-553.
4. Banner, D. W., D'Arcy, A., Chene, C., Winkler, F. K., Guha, A., Konigsberg, W. H., Nemerson, Y., & Kirchhofer, D. (1996) Nature 380, 41-46.
5. Bode, W. (1979) J. Mol. Biol. 127, 357-374.
6. Bode, W., & Schwager, P. (1975) FEBS Lett. 56, 139-143.
7. Bode, W., & Huber, R. (1992) Eur. J. Biochem. 204, 433-451.
8. Butler, A., Tsunoda, S., McCobb, D. P., Wei, A., & Salkoff, L. (1993) Science 261, 221-224.
9. Chiancone, E., Drakenberg, T., Teleman, O., & Forsen, S. (1985) J. Mol. Biol. 185, 210-207.
10. Dufton, M. J. (1985) Eur. J. Biochem. 153, 647-654.
11. Durrell, S. R., & Guy, R. (1992) Biophys. J. 62, 238-250.
12. Dworetzky, S. I., Trojnacki, J. T., & Gribkoff, V. K. (1994) Mol. Brain Res. 27, 189-193.
13. Empie, M. W., & Laskowski, M. (1982) Biochemisty 21, 2274-2284.
14. Escobar, L., Root, M. J., & MacKinnon, R. (1993) Biochemistry 32, 6982-6987.
15. Folander, K., & Swanson, R. (1995) Soc. Neurosci. Abstr. 21, 1326.
16. Frohman, M. A., Dush, M. K., & Martin, G. R. (1988) Proc. Natl. Acad. Sci. U.S.A. 85, 8998-9002.
17. Fujinaga, M., Sielecki, A. R., Read, R. J., Ardelt, W., Laskowski, M., & James, M. N. G. (1987) J. Mol. Biol. 195, 397-418.
18. Guo, X., Uehara, A., Ravindran, A., Bryant, S. H., Hall, S., & Moczydlowski, E. (1987) Biochemistry 26, 7546-7556.
19. Hurst, R. S., Busch, A. E., Kavanaugh, M. P., Osborne, P. B., North, R. A., & Adelman, J. P. (1991) Mol. Pharmacol. 40, 572-576.
20. Janin, J., & Chothia, C. (1990) J. Biol. Chem. 265, 16027-16030.
21. Knaus, H.-G., Folander, K., Garcia-Calvo, M.; Garcia, M. L., Kaczorowski, G. J., Smith, M., & Swanson, R. (1994) J. Biol. Chem. 269, 17274-17278.
22. Laskowski, M., Jr., & Kato, I. (1980) Annu. Rev. Biochem. 49, 593-626.
23. Laskowski, M., Kato, I., Ardelt, W., Cook, J., Demon, A., Empie, M. W., Kohr, W. J., Park, S. J., Parks, K., Schatzley, B. L., Schoenberger, O. L., Tashiro, M., Vichot, G., Whatley, H. E., Wieczorek, A., & Wieczorek, M. (1987) Biochemistry 26, 202-221.
24. Latorre, R. (1994) in Handbook of Membrane Channels: Molecular and Cellular Physiology (Peracchia, C., Ed.) pp 79-102, Academic Press, San Diego, CA.
25. Lucchesi, K., & Moczydlowski, E. (1990) Neuron 2, 141-148.
26. Lucchesi, K. J., & Moczydlowski, E. (1991) J. Gen. Physiol. 97, 1295-1319.
27. Marshall, J., Molloy, R., Moss, G. W. J., Howe, J. R., & Hughes, T. E. (1995) Neuron 14, 211-215.
28. McCobb, D. P., Fowler, N. L., Featherstone, T., Lingle, C. J., Saito, M., James, E. K., & Salkoff, L. (1995) Am. J. Physiol. 269, H767-H777.
29. McManus, O. B., Harris, G. H., Giangiacomo, K. M., Feigenbaum, P., Reuben, J. P., Addy, M. E., Burka, J. F., Kaczorowski, G. J., & Garcia, M. L. (1993) Biochemistry 32, 6128-6133.
30. McManus, O. B., Helms, L. M. H., Pallanck, L., Ganetzky, B., Swanson, R., & Leonard, R. J. (1995) Neuron 14, 645-650.
31. Meera, P., Wallner, M., & Toro, L. (1996) Biophys. J. 70, A13.
32. Miller, C. (1988) Neuron 1, 1003-1006.
33. Miller, C. (1995) Neuron 15, 5-10.
34. Miller, C., Moczydlowski, R., Latorre, R., & Phillips, M. (1985) Nature 313, 316-318.
35. Moczydlowski, E. (1992) Methods Enzymol. 207, 791-806.
36. Moczydlowski, E., Moss, G. W. J., & Lucchesi, K. J. (1992) Biochem. Pharmacol. 43, 21-28.
37. Moss, G. W. J., and Moczydlowski, E. (1996) J. Gen. Physiol. 107, 47-68.
38. Moss, G. W. J., Marshall, J., Morabito, M., Moczydlowski, E. G., and Howe, J. R. (1995) Biophys. J. 68, A29.
39. Moss, G. W. J., Marshall, J., & Moczydlowski, E. (1996) J. Gen. Physiol. (in press).
40. Pallanck, L., & Ganetzky, B. (1994) Hum. Mol. Genet. 3, 1239-1243.
41. Pallota, B. S., Blatz, A. L., & Magleby, K. (1992) Methods Enzymol. 207, 194-207.
42. Petersen, L. C., Birktoft, J. J., & Flodgaard, H. (1993) Eur. J. Biochem. 214, 271-279.
43. Read, R. J., & James, M. N. G. (1986) in Proteinase Inhibitors (Barret, A. J., & Salveson, G., Eds.) pp 301-336, Elsevier, Amsterdam.
44. Sabharwal, A. K., Birktoft, J. J., Gorka, J., Wildgoose, P., Petersen, L. C., & Bajaj, S. P. (1995) J. Biol. Chem. 270, 15523-15530.
45. Schild, L., & Moczydlowski, E. (1991) Biophys. J. 59, 523-537.
46. Schweitz, H., Bruhn, T., Guillemare, E., Moinier, D., Lancelin, J.-M., Beress, L., & Lazdunski, M. (1995) J. Biol. Chem. 270, 25121-25126.
47. Scott, M. J., Huckaby, C. S., Kato, I., Kohr, W. J., Laskowski, M., Jr., Tsai, M.-J., & O'Malley, B. W. (1987) J. Biol. Chem. 262, 5899-5907.
48. Skarzynski, T. (1992) J. Mol. Biol. 224, 671-683.
49. Sun, T., Naini, A. A., & Miller, C. (1994) Biochemistry 33, 9992-9999.
50. Swartz, K. J., & MacKinnon, R. (1995) Neuron 15, 941-949.
51. Tomimatsu, Y., Clary, J. J., & Bartulovich, J. J. (1966) Arch. Biochem. Biophys. 115, 536-544.
52. Tseng-Crank, J., Foster, C. D., Krause, J. D., Mertz, R., Godinot, N., DiChiara, T. J., & Reinhart, P. H. (1994) Neuron 13, 1315-1330.
53. Vincent, J.-P., & Lazdunski, M. (1972) Biochemistry 11, 2967-2977.
54. Vincent, J.-P., & Lazdunski, M. (1976) FEBS Lett. 63, 240-244.
55. Wallner, M., Meera, P., Ottolia, M., Kaczorowski, G., Latorre, R., Garcia, M., Stefani, E., & Toro, L. (1995) Recept. Channels 3, 185-189.
56. Wei, A., Solaro, C., Lingle, C., & Salkoff, L. (1994) Neuron 13, 671-681.
57. Wlodawer, A., Deisenhofer, J., & Huber, R. (1987) J. Mol. Biol. 193, 145-156.
58. Yellen, G. (1982) Nature 296, 357-359.