Enhanced delivery of carboplatin into brain tumours with intravenous Cereport(TM) (RMP-7): Dramatic differences and insight gained from dosing parameters

British Journal of Cancer

Volumn 80, Issue 7, 1999, Pages 964-970

  Emerich, D F ^a   Snodgrass, P ^a   Dean, R ^a   Agostino, M ^a   Hasler, B ^a   Pink, M ^a   Xiong, H ^a   Kim, B S ^a   Bartus, R T ^a,b  

^a ALKERMES INC   (United States)

^b TUFTS MEDICAL CENTER   (United States)

Author keywords

Blood brain barrier; Chemotherapy; Drug delivery; Glioma; Tumour barrier

Indexed keywords

BRADYKININ B2 RECEPTOR AGONIST; CARBOPLATIN; LOBRADIMIL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN TUMOR; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG UPTAKE; GLIOMA; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PHARMACODYNAMICS; PRIORITY JOURNAL; RAT; TACHYPHYLAXIS;

ANIMALS; ANTINEOPLASTIC AGENTS; BLOOD-BRAIN BARRIER; BRADYKININ; BRAIN NEOPLASMS; CARBOPLATIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DRUG SYNERGISM; GLIOMA; MALE; NEOPLASM TRANSPLANTATION; RATS; RATS, INBRED F344; TACHYPHYLAXIS;

EID: 0032902957     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6690450     Document Type: Article

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