A comparative study of cytokine gene transcripts in normal and malignant breast tissue and primary cell cultures derived from the same tissue samples

International Journal of Cancer

Volumn 66, Issue 4, 1996, Pages 551-556

  Speirs, Valerie ^a   Green, Andrew R ^a   White, Michael C ^a  

^a UNIVERSITY OF HULL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LYMPHOTOXIN;

ADULT; ARTICLE; BREAST CANCER; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; IMMUNOPHENOTYPING; PRIORITY JOURNAL;

BASE SEQUENCE; BREAST; BREAST NEOPLASMS; CELLS, CULTURED; CYTOKINES; DNA PRIMERS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MOLECULAR SEQUENCE DATA; NEPRILYSIN; RNA, MESSENGER; TUMOR CELLS, CULTURED; VIMENTIN;

EID: 0029948150     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19960516)66:4<551::AID-IJC21>3.0.CO;2-9     Document Type: Article

References (27)

1. ADAMS, E.F., RAFFERTY, B. and WHITE, M.C., Interleukin 6 is secreted by breast fibroblasts and stimulates 17β-oestradiol oxidoreductase activity of MCF-7 cells; possible paracrine regulation of breast 17β-oestradiol levels. Int. J. Cancer, 49, 118-121 (1991).
2. BASOLO, F., CALVO, S., FIORE, L., SERRA, C., CONALDI, P.G., FALCONE, V., MORGANTI, M., SOUARTINI, F. and TONIOLO, A., Production of cytokines and response to them in normal and transformed human mammary epithelial cells. Ann. N.Y. Acad. Sci., 698, 126-130 (1993a).
3. BASOLO, F., CONALDI, P.G., FIORE, L., CALVO, S. and TONIOLO, A., Normal breast epithelial cells produce interleukins 6 and 8 together with tumor-necrosis factor: defective IL6 expression in mammary carcinoma. Int. J. Cancer, 55, 926-930 (1993b).
4. BERTHON, P., PANCINO, G., DE CREMOUX, P., ROSETO, A., GESPACH, C. and CALVO, F., Characterisation of normal breast epithelial cells in primary cultures: differentiation and growth factor receptor studies. In Vitro cell. dev. Biol., 28A, 716-724 (1992).
5. BOYLE-WALSH, E., HASHIM, I.A., SPEIRS, V., FRASER, W.D. and WHITE, M.C., Interleukin-6 (IL-6) production and cell growth of cultured human meningiomas: interactions with interleukin-1β (IL-1β) and interleukin-4 (IL-4) in vitro. Neurosci. Lett., 170, 129-132 (1994).
6. CHOMCZYNSKI, P. and SACCHI, N., Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform. Anal. Biochem., 162, 156-159 (1987).
7. DINARELLO, C.A., Interleukin-1. In: A.W. Thomson (ed.), The cytokine handbook, pp. 47-82, Academic Press, London (1991).
8. DUNCAN, L.J., COLDHAM, N.G. and REED, M.J., The interaction of cytokines in regulating oestradiol 17β-oxidoreductase activity in MCF-7 cells. J. Steroid Biochem. mol. Biol., 49, 63-68 (1994).
9. EMERMAN, J.T. and WILKINSON, D.A., Routine culturing of normal, dysplastic and malignant human mammary epithelial cells from small tissue samples. In Vitro cell. dev. Biol., 26, 1186-1194 (1990).
10. ERROI, A., SIRONI, M., CHIAFFARINO, F., ZHEN-GUO, C., MENGOZZI, M. and MANTOVANI, A., IL-1 and IL-6 release by tumor-associated macrophages from human ovarian cancer. Int. J. Cancer, 44, 795-801 (1989).
11. GABELMAN, B.M. and EMERMAN, J.T., Effects of estrogen, epidermal growth factor and transforming growth factor-α on the growth of human breast epithelial cells in primary culture. Exp. Cell Res., 201, 113-118 (1992).
12. GREEN, A.R., WHITE, M.C. and SPEIRS, V., Elevated expression of IL-1β and IL-8 mRNA in neoplastic human breast tissue. Brit. J. Cancer, 71, P124 (1995).
13. HSU, S.M., RAINE, L. and FANGER, H., The use of avidin-biotin-complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabelled antibody (PAP) procedures. J. Histochem. Cytochem., 29, 577-580 (1981).
14. KOVER, K., LIANG, L., ANDREWS, G.K. and DEY, S.K., Differential expression and regulation of cytokine genes in the mouse uterus. Endocrinology, 136, 1666-1673 (1995).
15. O'HARE, M.J., ORMEROD, M.G., MONAGHAN, P., LANE, E.B. and GUSTERSON, B.A., Characterisation in vitro of luminal and myoepithelial cells isolated from the human mammary gland by cell sorting. Differentiation, 46, 209-221 (1991).
16. PERUSINGHE, N.P., MONAGHAN, P., O'HARE, M.J., ASHLEY, S. and GUSTERSON, B.A., Effects of growth factors on proliferation of basal and luminal cells in human breast epithelial explants in serum free culture. In Vitro cell. dev. Biol., 28A, 90-96 (1992).
17. RONNOV-JESSEN, L., PETERSEN, O.W., KOTELIANSKY, V.E. and BISSELL, M.J., The origin of myofibroblasts in breast cancer. J. Clin. Invest., 95, 859-873 (1995).
18. RUDDLE, N.H. and TURETSKAYA, R.L., Tumour necrosis factor beta. In: A.W. Thomson (ed.), The cytokine handbook, pp. 257-267, Academic Press, London (1991).
19. SAKTHIVEL, R., HAMDEN, M., YANG, J., RAPHAEL, R.C. and NANDI, S., Effect of TGF-alpha on growth of normal human breast epithelial cells in serum-free primary culture using 3-dimensional collagen gels. Cell Biol. Int., 17, 387-397 (1993).
20. SCHINDLER, R., MANCILLA, J., ENDRES, S., GHORBANI, R., CLARK, S.C. and DINARELLO, C.A., Correlations and interactions in the production of interleukin-6 (IL-6), IL-1 and tumour necrosis factor (TNF) in human blood mononuclear cells: IL-6 suppresses IL-1 and TNF. Blood, 75, 40-47 (1990).
21. SOULE, H.D., VASQUEZ, J., LONG, A., ALBERT, S. and BRENNAN, M., A human cell line from a pleural effusion derived from a breast carcinoma. J. nat. Cancer Inst., 51, 1409-1413 (1973).
22. SPEIRS, V., ADAMS, E.F., RAFFERTY, B. and WHITE, M.C., Interactive effects of interleukin-6, 17β-estradiol and progesterone on growth and 17β-hydroxysteroid dehydrogenase activity in human breast carcinoma cells. J. Steroid Biochem. mol. Biol., 46, 11-15 (1993).
23. SPEIRS, V., BIRCH, M.A., BOYLE-WALSH, E., GREEN, A.R., GALLAGHER, J.A. and WHITE, M.C., Interleukin-3: a putative protective factor against breast cancer which is secreted by male but not female breast fibroblasts. Int. J. Cancer, 61, 416-419 (1995a).
24. SPEIRS, V., GREEN, A.R., TODD, V.L. and WHITE, M.C., Cytokine expression in normal and neoplastic breast tissue. In: C.J. Wilde, M. Peaker and C.H. Knight (eds.), Intracellular signalling in the mammary gland, pp. 101-102, Plenum Press, New York (1995b).
25. SPEIRS, V., GREEN, A.R. and WHITE, M.C., Collagenase III: a superior enzyme for complete disaggregation and improved viability of normal and malignant human breast tissue. In Vitro cell. dev. Biol. 32, 72-74 (1996).
26. VAN DAMME, J., Interleukin-8 and related molecules. In: A.W. Thomson (ed.), The cytokine handbook, pp. 201-214, Academic Press, London (1991).
27. WATSON, J. and CHUAH, S.Y., Techniques for the primary culture of human breast cancer cells and measurement of their prostaglandin secretion. Clin. Sci., 83, 347-352 (1992).