Dual actions of the metabolic inhibitor, sodium azide on KATP channel currents in the rat CRI-G1 insulinoma cell line

British Journal of Pharmacology

Volumn 126, Issue 1, 1999, Pages 51-60

  Harvey, J ^a   Hardy, S C ^a   Ashford, M L J ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

Azide; Katp channels; Mitochondrial inhibitors; Oligomycin; Rotenone

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE MAGNESIUM; ADENYLYLIMIDODIPHOSPHATE; GLUCOSE; OLIGOMYCIN; POTASSIUM CHANNEL; POTASSIUM ION; ROTENONE; SODIUM AZIDE; TOLBUTAMIDE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; HYPERPOLARIZATION; INSULINOMA; NONHUMAN; PATCH CLAMP; POTASSIUM CONDUCTANCE; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT;

ADENOSINE TRIPHOSPHATE; ADENYLYL IMIDODIPHOSPHATE; ANIMALS; ELECTRIC CONDUCTIVITY; ENZYME INHIBITORS; INSULINOMA; MEMBRANE POTENTIALS; OLIGOMYCINS; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; RATS; ROTENONE; SODIUM AZIDE; TUMOR CELLS, CULTURED; UNCOUPLING AGENTS;

EID: 0032893376     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702267     Document Type: Article

References (36)

1. ALLARD, B., LAZDUNSKI, M. & ROUGIER, O. (1995). Activation of ATP-dependent K+ channels by metabolic poisoning in adult mouse skeletal muscle: role of intracellular Mg2+ and pH. J. Pliysiol., 485, 283-296.
2. ASHCROFT, S.J.H. & ASHCROFT, P.M. (1990). Properties and functions of ATP-sensitive K+ channels. Cell. Signalling, 2, 197-214.
3. ASHCROFT, P.M. & RORSMAN, P. (1991). Electrophysiology of the pancreatic cell. Prog. Biophys. Mol. Biol.. 54, 87-143.
4. ASHFORD, M.L.J. (1990). Potassium channels and modulation of insulin secretion. In Potassium Channels: Structure, Classification, Function and Therapeutic Potential. Cook, N.S. (ed). pp. 300-325. Chichester: Ellis Horwood Limited.
5. BABENKO, A.P., AGUILAR-BRYANT, L. & BRYAN, J. (1998). A view of SUR/6.X, KATP channels. Anna. Rev. Pliysiol., 60, 667-687.
6. CARRINGTON, C.A, RUBERY, E.D, PEARSON, E.C. & HALES, C.N. (1986). Five new insulin-producing cell lines with differing secretory properties. J. Endocrinol., 109, 193-200.
7. DÜNNE, M.J., ILLOT, M.C. & PETERSEN, O.H. (1987). Interaction of diazoxide, tolbutamide and ATP4~ on nucleotide-dependent K + channels in an insulin-secreting cell line. J. Membr. Biol., 99, 215-224.
8. DUNNE, M.J. (1989). Protein phosphorylation is required for diazoxide to open ATP-sensitive potassium channels in insulin (RIN m5F) secreting cells. FEBS Lett., 208, 262-266.
9. GRIBBLE, P.M., ASHFIELD, R., AMMALA, C. & ASHCROFT, P.M. (1997a). Properties of cloned ATP-sensitive K+ currents expressed in Xenopus oocytes. J. Pliysiol., 498, 87-98.
10. CRIBBLE, P.M., TUCKER, S.J. & ASHCROFT, P.M. (1997b). The essential role of the Walker A motifs of SURI in K-ATP channel activation by Mg-ADP and diazoxide. EM BO J.. 16,1145 -1152.
11. GRIMMSMANN, T. & RUSTENBECK, I. (1998). Direct effects of diazoxide on mitochondrial in pancreatic /?-celIs and on isolated liver mitochondria. Br. J. Pharmacol., 123, 781-788.
12. HARVEY, J., MCKENNA, F., HERSON, P.S., SPANSWICK, D. & ASHFORD, M.L.J. (1997). Leptin activates ATP-sensitive potassium channels in the rat insulin-secreting cell line, CRI-G1. J. Physiol., 504, 527-535.
13. INAGAKI, N., GONOI, T., CLEMENT, J.P., NAMBA, N., INAZAWA, J., GONZALEZ, G., AGUILAR-BRYAN, L., SEING, S. & BRYAN, J. (1995). Reconstitution of IKATP: an inward rectifier subunit plus the sulphonylurea receptor. Science, 270, 1166-1169.
14. INAGAKI, N., GONOI, T., CLEMENT, J.P., WANG, C.Z., AGUILARBRYAN, L., BRYAN, J. & SEING, S. (1996). A family of sulphonylurea receptors determines the sensitivity of the pharmacological properties of ATP-sensitive K+ channels. Neuron, 16, 1011-1017.
15. ITO, IL, NAKAJIMA, T., TAKIKAWA, R., HAMADA, E., IGUCHI, M., SUGIMOTO.T. & KURACHI, Y. (1991). Coenzyme Q10 attenuates cyanide-activation of the ATP-sensitive K+ channel current in single cardiac myocytes of the guinea-pig. Arch. Pharmacol., 344, 133-136.
16. KAKEI, M. & NOMA, A. (1984). Adenosine 5'-triphosphate-sensitive single potassium channel in the atrio ventricular node cell of the rabbit heart. J. Physiol., 352, 265-284.
17. KOZLOWSKI, R.Z., HALES, C.N. & ASHFORD, M.L.J. (1989). Dual effects of diazoxide on ATP-K + currents recorded from an insulin-secreting cell line. Br. J. Pharmacol.. 97, 1039-1050.
18. LEE, K., OZANNE, S.E., ROWE, I.C.M., HALES, C.N. & ASHFORD, M.L.J. (1994). The effects of trypsin of ATP-sensitive potassium channel properties and sulphonylurea receptors in the CRI-G1 insulin secreting cell line. Mol. Pharmacol., 45, 176-185.
19. LEE, K., ROWE, I.C.M. & ASHFORD, M.L.J. (1995). Characterisation of an ATP-modulated large conductance Ca2 +-activated K + channel present in rat cortical neurones. J. Physio!., 488, 319-337.
20. MISLER, S., FALKE, L.C., GILLIS, K. & MCDANIEL, M.L. (1986). A metabolic-regulated potassium channel in rat pancreatic beta cells. Proc. Nat!. Acad. Sei. U.S.A., 83, 7119-7123.
21. MISLER, S., GEE, W.M., GILLIS, K.D., SCHARF, D.W. & FALKE, L.C. (1989). Metabolic-regulated ATP-sensitive K+ channel in human pancreatic islets. Diabetes, 38, 422-427.
22. MURPHY, K.P.S.J. & GREENFIELD, S.A. (1991). ATP-sensitive potassium channels counteract anoxia in neurones of the substantia nigra. Exp. Brain. Res., 84, 355-358.
23. NICHOLS, C.G., SHYNG, S.-L., NESTOROWICZ, A., GLASER, B., CLEMENT, J., GONZALEZ, G., AGUILAR-BRYAN, L., PERMUTT, A.M. & BRYAN, J.P. (1996). Adenosine diphosphate as an intracellular regulator of insulin secretion. Science, 272, 1785-1787.
24. NIKI, I., ASHCROFT, F.M. & ASHCROFT, S.J. (1989). The dependence on intracellular ATP concentration of ATP-sensitive K-channels and of Na,K-ATPase in intact H1T-T15 beta cells. FEBS Lett.. 257,361-364.
25. PENEFSKY, H.S. (1985). Mechanism of inhibition of mitochondrial adenosine triphosphate by dicyclohexylcarbodiimide and oligomycin: relationship to ATP synthesis. Proc. Natl. Acad. Sei. U.S.A., 82, 1589-1593.
26. RAGaN, C.I. & RACKER, E. (1973). Resolution and reconstitution of the mitochondrial electron transport system IV. The reconstitution of the rotenone-sensitive reduced nicotinamide adenine dinucleotide-ubiquinone reductase from reduced nicotinamide adenine dinucleotide dehydrogenase and phospholipids. J. Biol. Chem., 248, 6876-6884.
27. ROPER, J. & ASHCROFT, P.M. (1995). Metabolic inhibition and low internal ATP activate K-ATP channels in rat dopaminergic substantia nigra neurones, fugers Arch. Etir. J. Physiol., 430, 44-54.
28. RUSTENBECK, I., HERRMENN, C. & GRIMMSMANN, T. (1997). Energetic requirement of insulin secretion distal to calcium influx. Diabetes, 46, 1305-1311.
29. SAKURA, H., AMMALA, C., SMITH, P.A. & ASHCROFT, P.M. (1995). Cloning and functional expression of the cDNA encoding a novel ATP-sensitive potassium channel expressed in pancreatic beta cells, brain, heart and skeletal muscle. FEBS Lett., 377,338 - 344.
30. SENIOR, A.E. (1988). ATP synthesis by oxidative phosphorylation. Physiol. Rev., 68, 177-231.
31. SHYNG, S.-L., FERRIGNI, T. & NICHOLS, C.G. (1997). Regulation of KATP channel activity by diazoxide and MgADP; Distinct functions of the two nucleotide binding folds of the sulphonylurea receptor. J. Gen. Physiol., 110, 643-654.
32. STURGESS, N.C., KOZLOWSK.I, R.Z., CARRINGTON, C.A., HALES, C.N. & ASHFORD, M.L.J. (1988). Effects of sulphonylureas and diazoxide on insulin secretion and nucleotide-sensitive channels in an insulin-secreting cell line. Br. J. Pharmacol.. 95, 83-94.
33. TRÜBE, G., RORSMAN, P. & OHNO-SHOSAKU, T. (1986). Opposite effects of tolbutamide and diazoxide on the ATP-sensitive K + channel in mouse pancreatic beta cells. Pugers Arch., 407,493-499.
34. TSUBAKI, M. & YOSHIKAWA, S. (1993). Fourier-transform infra-red study of azide binding to the Fe3-CuB binuclear site of bovine cytochrome oxidase. Biochem.. 32, 174-182.
35. TUCKER, S.J., CRIBBLE, P.M., ZHAO, C, TRAPP, S. & ASHCROFT, P.M. (1997). Truncation of Kir6.2 produces ATP-sensitive K + channels in the absence of the sulphonylurea receptor. Nature. 387, 179-183.
36. WEISS, J.N. & LAMP, S.T. (1987). Glycolysis preferentially inhibits ATP-sensitive K+ channels in isolated guinea pig cardiac myocytes. Science, 238, 67-69.