Vascular smooth muscle cell proliferation and regrowth after mechanical injury in vitro are Egr-1/NGFI-A-dependent

American Journal of Pathology

Volumn 155, Issue 3, 1999, Pages 897-905

  Santiago, Fernando S ^a   Atkins, David G ^b   Khachigian, Levon M ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b JOHNSON AND JOHNSON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; OLIGONUCLEOTIDE; PHOSPHOROTHIOIC ACID;

ANIMAL CELL; ANIMAL TISSUE; ARTERY WALL; ARTICLE; CELL COUNT; CELL GROWTH; CELL PROLIFERATION; GENE SEQUENCE; HEART MUSCLE INJURY; IMMEDIATE EARLY GENE; NONHUMAN; PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY; PRIORITY JOURNAL; PROMOTER REGION; RAT; RNA SYNTHESIS; SMOOTH MUSCLE FIBER; THEORY; WESTERN BLOTTING;

EID: 0032886118     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)65189-9     Document Type: Article

References (41)

1. Fischman DL, Leon MB, Baim D, Schatz RA, Savage MP, Penn I, Detre K, Veltri L, Ricci D, Nobuyoshi M: A randomized comparison of coronary stent placement and balloon angioplasty in the treatment of coronary artery disease. N Engl J Med 1994;331:496-501
2. Jackson CL, Schwartz SM: Pharmacology of smooth muscle replication. Hypertension 1992, 20:713-736
3. O'Brien ER, Schwartz SM: Update on the biology and clinical study of restenosis. Trends Cardiovasc Med 1994, 4:169-178
4. Ross R: The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 1993, 362:801-809
5. Sukhatme VP, Cao X, Chang LL, Tsai-Morris C-H, Stamenkovich D, Ferreira PCP, Cohen DR, Edwards SA, Shows TB, Curran T, Le Beau MM, Adamson ED: A zinc finger encoding gene coregulated with c-Fos during growth and differentiation and after depolarization. Cell 1988, 53:37-43
6. Gashler A, Sukhatme V: Early growth response protein 1 (Egr-1): prototype of a zinc-finger family of transcription factors. Prog Nucleic Acids Res 1995, 50:191-224
7. Changelian PS, Feng P, King TC, Milbrandt J: Structure of the NGFI-A gene and detection of upstream sequences responsible for its transcriptional induction by nerve growth factor. Proc Natl Acad Sci USA 1989, 86:377-381
8. Pavletich NP, Pabo CO: Zinc finger-DNA recognition: crystal structure of a zif268-DNA complex at 2.1A. Science 1991, 252:809-817
9. Khachigian LM, Williams AJ, Collins T: Interplay of Sp1 and Egr-1 in the proximal PDGF-A promoter in cultured vascular endothelial cells. J Biol Chem 1995, 270:27679-27686
10. Khachigian LM, Lindner V, Williams AJ, Collins T: Egr-1-induced endothelial gene expression: a common theme in vascular injury. Science 1996, 271:1427-1431
11. Biesiada E, Razandi M, Levin ER: Egr-1 activates basic fibroblast growth factor transcription. J Biol Chem 1996, 271:18576-18581
12. Khachigian LM, Collins T: Inducible expression of Egr-1-dependent genes: a paradigm of transcriptional activation in vascular endothelium. Circ Res 1997, 81:457-461
13. Yan YX, Nakagawa H, Lee MH, Rustgi AK: Transforming growth factor-α enhances cyclin D1 transcription through the binding of early growth response protein to a cis-regulatory element in the cyclin D1 promoter. J Biol Chem 1997, 272:33181-33190
14. Hallahan DE, Dunphy E, Virudachalam S, Sukhatme VP, Kufe DW, Weischselbaum RR: c-jun and Egr-1 participate in DNA synthesis and cell survival in response to ionizing radiation exposure. J Biol Chem 1995, 270:30303-30309
15. Kim S, Kawamura M, Wanibuchi H, Ohta K, Hamaguchi A, Omura T, Yulimura T, Miura K, Iwao H. Angiotensin II type 1 receptor blockade inhibits the expression of immediate-early genes, and fibronectin in rat injured artery. Circulation 1995, 92:88-95
16. Silverman ES, Khachigian LM, Lindner V, Williams AJ, Collins T: Inducible PDGF A-chain transcription in vascular smooth muscle cells is mediated by Egr-1 displacement of Sp1 and Sp3. Am J Physiol 1997, 42:H1415-H1426
17. Khachigian LM, Chesterman CN: Synthetic peptides representing the alternatively spliced exon of the PDGF A-chain modulate mitogenesis stimulated by normal human serum and several growth factors. J Biol Chem 1992, 267:7478-7482
18. Zuker M: On finding all suboptimal foldings of an RNA molecule. Science 1989, 244:48-52
19. Bennett CF, Chiang M-Y, Chan H, Shoemaker JE, Mirabelli CK: Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides. Mol Pharmacol 1992, 41:1023-1033
20. Beltinger C, Saaragovi HU, LeSauteur L, Shah N, DeDionisio L, Christensen L, Raible A, Jarett L, Gewirtz AM: Binding, uptake and intracellular trafficking of phosphorothioate-modified oligodeoxynucleotides. J Clin Invest 1995, 95:1814-1823
21. Bennett MR, Schwartz SM: Antisense therapy for angioplasty restenosis. Circulation 1995, 92:1981-1993
22. Wyroba E, Pawlowska Z, Kobylanska A, Pluskota E, Maszewska M, Stec WJ, Cierniewski CS: Internalization of oligodeoxynucleotide antisense to type-1 plasminogen activator inhibitor mRNA in endothelial cells: a three dimensional reconstruction by confocal microscopy. Biol Cell 1996, 87:37-43
23. Hofer G, Grimmer C, Sukhatme VP, Sterzel RB, Rupprecht HD: Transcription factor Egr-1 regulates glomerular mesangial cell proliferation. J Biol Chem 1996, 271:28306-28310
24. Khachigian LM, Anderson KA, Halnon NJ, Resnick N, Gimbrone Jr MA, Collins T: Egr-1 is activated in endothelial calls exposed to fluid shear stress and interacts with a novel shear-stress response element in the PDGF A-chain promoter. Arterioscler Thromb Vase Biol 1997, 17:2280-2286
25. Delbridge GJ, Khachigian LM: FGF-1-induced PDGF A-chain gene expression in vascular endothelial cells involves transcriptional activation by Egr-1. Circ Res 1997, 81:282-288
26. Pitsch RJ, Goodham GR, Minion DJ, Madura JA, Fox PL, Graham LM: Inhibition of smooth muscle cell proliferation and migration in vitro by antisense oligonucleotide to c-myb. J Vasc Surg 1996, 23:783-791
27. Horodyski J, Powell RJ: Effect of aprotinin on smooth muscle cell proliferation, migration, and extracellular matrix synthesis. J Surg Res 1996, 66:115-118
28. Chen P, Gupta K, Wells A: Cell movement elicited by epidermal growth factor receptor requires kinase and autophosphorylation but is separable from mitogenesis. J Cell Biol 1994, 124:547-555
29. Ho TC, Del Priore LV, Hornbeck R: Effect of mitomycin C on human retinal pigment epithelium. Curr Eye Res 1997, 16:572-576
30. Villa AE, Guzman LA, Poptic EJ, Labhasetwar V, D'Souza S, Farrell CL, Plow EF, Levy RJ, DiCorleto PE, Topol EJ: Effects of antisense c-myb oligonucleotides on vascular smooth muscle cell proliferation and response to vessel wall injury. Circ Res 1995, 76:505-513
31. Bennett MR, Lindner V, Deblois D, Reidy MA, Schwartz SM: Effect of phosphorothioated oligonucleotides on neointima formation in the rat carotid artery: dissecting the mechanism of action. Arterioscler Thromb Vasc Biol 1997, 17:2326-2332
32. Bennett MR, Anglin S, McEwan JR, Jagoe R, Newby AC, Evan GI: Inhibition of vascular smooth muscle cell proliferation in vitro and in vivo by c-myc antisense oligodeoxynucleotides J Clin Invest 1994, 93:820-828
33. Autieri MV, Yue T-L, Ferstein GZ, Ohlstein E: Antisense oligonucleotides to the p65 subunit of NF-κB inhibit human vascular smooth muscle cell adherence and proliferation and prevent neointima formation in rat carotid arteries. Biochem Biophys Res Commun 1995, 213:827-836
34. Morishita R, Gibbons GH, Ellison KE, Nakajima M, Zhang L, Kaneda Y, Ogihra T, Dzau V: Single intraluminal delivery of antisense cdc2 kinase and proliferating-cell nuclear antigen oligonucleotides results in chronic inhibition of neointimal hyperplasia. Proc Natl Acad Sci USA 1993, 90:8474-8478
35. Marcus-Sekura C, Woerner A, Shinozuka K, Zon G, Quinnan G: Comparative inhibition of chloramphenicol acetyltransferase gene expression by antisense oligonucleotide analogues having alkyl triester, methyl phosphonate and phosphorothioate linkages. Nucleic Acids Res 1987, 15:5749-5763
36. Cazenave C, Stein C, Loreau N, Thuong N, Neckers L, Subasinghe C, Helene C, Cohen J, Toulme J: Comparative inhibition of rabbit globin mRNA translation by modified antisense oligodeoxynucleotides. Nucleic Acids Res 1989, 17:4225-4273
37. Krieg AM, Stem CA: Phosphorothioate oligonucleotides: antisense or anti-protein? Antisense Res Dev 1995, 5:241
38. Guvakova MA, Yakubov LA, Vlodavsky I, Tonkinson JL, Stein CA: Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors, and remove it from low affinity binding sites on extracellular matrix. J Biol Chem 1995, 270:2620-2627
39. Wang W, Chen HJ, Schwartz A, Cannon PJ, Stein CA, Rabbani LE: Sequence-independent inhibition of in vitro smooth muscle cell proliferation, migration, and in vivo neointimal formation by phosphorothioate oligonucleotides. J Clin Invest 1996, 98:443-450
40. Perochondorisse J, Chetouani F, Aurel S, Iscolo N, Michot B: RNA-D2: a computer program for editing and display of RNA secondary structures. Comp Appl Biosci 1995, 11:101-109
41. Chetouani F, Monestie P, Thebault P. Gaspin C, Michot B:. ESSA: an integrated and interactive computer tool for analysing secondary structure. Nucleic Acids Res 1997, 25:3514-3522