Long-lasting sensitization towards morphine in motoric and limbic areas as determined by c-fos expression in rat brain

Molecular Brain Research

Volumn 72, Issue 1, 1999, Pages 1-16

  Erdtmann Vourliotis, Martina ^a   Mayer, Peter ^a   Linke, Rüdiger ^a   Riechert, Uta ^a   Höllt, Volker ^a  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

C fos; Dorsal striatum; In situ hybridization; Morphine; Retrograde tracing; Sensitization

Indexed keywords

FLUOROGOLD; MORPHINE; TRACER;

ADOLESCENT; ANIMAL BEHAVIOR; ANIMAL TISSUE; ARTICLE; CHEMICAL LABELING; CINGULATE GYRUS; DRUG SENSITIZATION; EMOTION; GENE EXPRESSION; IN SITU HYBRIDIZATION; LIMBIC CORTEX; LOCOMOTION; MALE; MAMMILLARY BODY; MORPHINE TOLERANCE; MOTOR CORTEX; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; RAT; SEPTUM PELLUCIDUM; THALAMUS;

ANIMALS; CORPUS STRIATUM; DRUG TOLERANCE; EMOTIONS; GENE EXPRESSION REGULATION; GENES, FOS; HUMANS; LIMBIC SYSTEM; MALE; MORPHINE; MORPHINE DEPENDENCE; MOTOR ACTIVITY; MOTOR CORTEX; NERVE TISSUE PROTEINS; NEURAL PATHWAYS; ORGAN SPECIFICITY; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, WISTAR;

EID: 0032846640     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(99)00184-9     Document Type: Article

References (56)

1. Acquas E., DiChiara G. Depression of mesolimbic dopamine transmission and sensitization to morphine during opiate abstinence. J. Neurochem. 58:1992;1620-1625.
2. Babbini M., Davis W.M. Time-dose relationship for locomotor activity effects of morphine after acute or repeated treatment. Br. J. Pharmacol. 46:1972;213-224.
3. Babbini M., Gaiardi M., Bartoletti M. Persistence of chronic morphine effects upon activity in rats 8 months after ceasing the treatment. Neuropharmacology. 14:1975;611-614.
4. Baptista M.A., Siegel S., MacQueen G., Young L.T. Pre-drug cues modulate morphine tolerance, striatal c-Fos, and AP-1 DNA binding. NeuroReport. 9:1998;3387-3390.
5. Bartoletti M., Gaiardi M., Gubellini G., Bacchi A., Babbini M. Long-term sensitization to the excitatory effects of morphine. Neuropharmacology. 22:1983;1193-1196.
6. Berendse H.W., Groenewegen H.J. Organization of the thalamostriatal projections in the rat, with special emphasis of the ventral striatum. J. Comp. Neurol. 299:1990;187-228.
7. Berhow M.T., Hiroi N., Nestler E.J. Regulation of ERK (extracellular signal regulated kinase), part of the neurotrophin signal transduction cascade, in the rat mesolimbic dopamine system by chronic exposure to morphine or cocaine. J. Neurosci. 16:1996;4707-4715.
8. Bontempi B., Sharp F.R. Systemic morphine-induced FOS protein in the rat striatum and nucleus accumbens is regulated by mu opioid receptors in the substantia nigra and ventral tegmental area. J. Neurosci. 17:1997;8596-8612.
9. Brown L.L., Sharp F.R. Metabolic mapping of rat striatum: somatotopic organization of sensorimotor activity. Brain Res. 686:1995;207-222.
10. Brown L.L., Smith D.M., Goldbloom L.M. Organizing principles of cortical integration in the rat neostriatum: corticostriate map of the body surface is an ordered lattice of curved laminae and radial points. J. Comp. Neurol. 392:1998;468-488.
11. Chang S.L., Squinto S.P., Harlan R.E. Morphine activation of c-fos expression in rat brain. Biochem. Biophys. Res. Commun. 157:1988;698-704.
12. Cullinan W.E., Herman J.P., Battaglia D.F., Akil H., Watson S.J. Pattern and time course of immediate early gene expression in rat brain following acute stress. Neuroscience. 64:1995;477-505.
13. Cunningham S.T., Finn M., Kelley A.E. Sensitization of the locomotor response to psychostimulants after repeated opiate exposure: role of the nucleus accumbens. Neuropsychopharmacology. 16:1997;147-155.
14. Curran E.J., Akil H., Watson S.J. Psychomotor stimulant- and opiate-induced c-fos mRNA expression patterns in the rat forebrain: comparisons between acute drug treatment and a drug challenge in sensitized animals. Neurochemical Research. 21:1996;1425-1435.
15. Deroche V., Marinelli M., Maccari S., Le Moal M., Simon H., Piazza P.V. Stress-induced sensitization and glucocorticoids: I. Sensitization of dopamine-dependent locomotor effects of amphetamine and morphine depends on stress-induced corticosterone secretion. J. Neurosci. 15:1995;7181-7188.
16. Devine D.P., Wise R.A. Self-administration of morphine, DAMGO, and DPDPE into the ventral tegmental area of rats. J. Neurosci. 14:1994;1978-1984.
17. DiChiara G., North R.A. Neurobiology of opiate abuse. Trends Pharmacol. Sci. 13:1992;185-193.
18. Erdtmann-Vourliotis M., Riechert U., Mayer P., Grecksch G., Höllt V. Pentylenetetrazole(PTZ)-induced c-fos expression in the hippocampus of kindled rats is suppressed by concomitant treatment with naloxone. Brain Res. 792:1998;299-308.
19. Erdtmann-Vourliotis M., Mayer P., Riechert U., Grecksch G., Höllt V. Identification of brain regions that are markedly activated by morphine in tolerant but not in naive rats. Brain Res. Mol. Brain Res. 61:1998;51-61.
20. Erdtmann-Vourliotis M., Mayer P., Riechert U., Händel M., Kriebitzsch J., Höllt V. Rational design of oligonucleotide probes to avoid optimization steps in in situ hybridization. Brain Res. Protoc. 4:1999;82-91.
21. J.H. Fallon, S.E. Loughlin, Substantia nigra, in: G. Paxinos (Ed.), The Rat Nervous System, 2nd edn., Academic Press, San Diego, 1995.
22. A. Goldstein, Addiction. From Biology to Drug Policy, Freeman, New York, 1993.
23. Gutstein H.B., Thome J.L., Fine J.L., Watson S.J., Akil H. Pattern of c-fos mRNA induction in rat brain by acute morphine. Can. J. Physiol. Pharmacol. 76:1998;294-303.
24. L. Heimer, D.S. Zahm, G.F. Alheid, Basal ganglia, in: G. Paxinos (Ed.), The Rat Nervous System, 2nd edn., Academic Press, San Diego, 1995, pp. 579-628.
25. Herz A. Opioid reward mechanisms: a key role in drug abuse? Can. J. Physiol. Pharmacol. 76:1998;252-258.
26. Hoffmann O., Plesan A., Wiesenfeld-Hallin Z. Genetic differences in morphine sensitivity, tolerance and withdrawal in rats. Brain Res. 806:1998;232-237.
27. Honore P., Catheline G., Le Guen S., Besson J.M. Chronic treatment with systemic morphine induced tolerance to the systemic and peripheral antinociceptive effects of morphine on both carrageenin induced mechanical hyperalgesia and spinal c-Fos expression in awake rats. Pain. 71:1997;99-108.
28. Johnson S.W., North R.A. Opioids excite dopamine neurons by hyperpolarization of local interneurons. J. Neurosci. 12:1992;483-488.
29. Joyce E.M., Iversen S.D. The effect of morphine applied locally to mesencephalic dopamine cell bodies on spontaneous motor activity in the rat. Neurosci. Lett. 14:1979;207-212.
30. Koob G.F., Le Moal M. Drug abuse: hedonic homeostatic dysregulation. Science. 278:1997;52-58.
31. Lane-Ladd S.B., Pineda J., Boundy V.A., Pfeuffer T., Krupinski J., Aghajanian G.K., Nestler E.J. CREB (cAMP response element-binding protein) in the locus coeruleus: biochemical, physiological, and behavioral evidence for a role in opiate dependence. J. Neurosci. 17:1997;7890-7901.
32. Lett B.T. Repeated exposures intensify rather than diminish the rewarding effects of amphetamine, morphine and cocaine. Psychopharmacology. 98:1989;357-362.
33. 1 and N-methyl-D-aspartate receptors. Proc. Natl. Acad. Sci. U.S.A. 91:1994;8537-8541.
34. S.E. Loughlin, F.M. Leslie, J.H. Fallon, Endogenous opioid systems, in: G. Paxinos (Ed.), The Rat Nervous System, 2nd edn., Academic Press, San Diego, 1995, pp. 975-1001.
35. Mansour A., Khachaturian H., Lewis M.E., Akil H., Watson S.J. Autoradiographic differentiation of mu, delta, and kappa opioid receptors in the rat forebrain and midbrain. J. Neurosci. 7:1987;2445-2464.
36. Matthews R.T., German D.C. Electrophysiological evidence for excitation of rat ventral tegmental area dopamine neurons by morphine. Neuroscience. 11:1984;617-625.
37. McGeorge A.J., Faull R.L. The organization of the projection from the cerebral cortex to the striatum in the rat. Neuroscience. 29:1989;503-537.
38. Nestler E.J., Berhow M.T., Brodkin E.S. Molecular mechanisms of drug addiction: adaptations in signal transduction pathways. Mol. Psychiatry. 1:1996;190-199.
39. R. Nieuwenhuys, J. Voogd, C. van Huijzen, The Human Central Nervous System: a Synopsis and Atlas, 2nd rev. edn., Springer, Berlin, 1981.
40. Nomikos G., Spyraki C., Kazandjan A., Sfikakis A. Estrogen treatment to ovariectomized rats modifies morphine induced behavior. Pharmacol. Biochem. Behav. 27:1987;611-617.
41. Papez J.W. A proposed mechanism of emotion. Arch. Neurol. Psychiatry. 38:1937;725-743.
42. G. Paxinos, C. Watson, The Rat Brain in Stereotaxic Coordinates, 3rd edn., Academic Press, San Diego, 1997.
43. J.L. Price, Thalamus, in: G. Paxinos (ed.), The Rat Nervous System, 2nd edn., Academic Press, San Diego, 1995, pp. 629-648.
44. Robinson T.E., Berridge K.C. The neural basis of drug craving: an incentive-sensitization theory of addiction. Brain Res. Rev. 18:1993;247-291.
45. Sharp F.R., Liu J., Nickolenko J., Bontempi B. NMDA and D1 receptors mediate induction of c-fos and junB genes in striatum following morphine administration: implications for studies of memory. Behav. Brain Res. 66:1995;225-230.
46. Shippenberg T.S., LeFevour A., Thompson A.C. Sensitization to the conditioned rewarding effects of morphine and cocaine: differential effects of the kappa-opioid receptor agonist U69593. Eur. J. Pharmacol. 345:1998;27-34.
47. Smith M.A., Banerjee S., Gold P.W., Glowa J. Induction of c-fos mRNA in rat brain by conditioned and unconditioned stressors. Brain Res. 578:1992;135-141.
48. Spanagel R., Herz A., Shippenberg T.S. Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway. Proc. Natl. Acad. Sci. U.S.A. 89:1992;2046-2050.
49. Spanagel R., Shippenberg T.S. Modulation of morphine-induced sensitization by endogenous kappa opioid systems in the rat. Neurosci. Lett. 153:1993;232-236.
50. Spanagel R. Modulation of drug induced sensitization processes by endogenous opioid systems. Behav. Brain Res. 70:1995;37-49.
51. Stewart J. Conditioned and unconditioned drug effects in relapse to opiate and stimulant drug self-administration. Prog. Neuro-Psychopharmacol. Biol. Psychiatry. 7:1983;591-597.
52. Vanderschuren L.J., Tjon G.H., Nestby P., Mulder A.H., Schoffelmeer A.N., deVries T.J. Morphine-induced long-term sensitization to the locomotor effects of morphine and amphetamine depends on the temporal pattern of the pretreatment regimen. Psychopharmacology (Berlin). 131:1997;115-122.
53. Vasko M.R., Domino E.F. Tolerance development to the biphasic effects of morphine on locomotor activity and brain acetylcholine in the rat. J. Pharmacol. Exp. Ther. 207:1978;848-858.
54. Vezina P., Kalivas P.W., Stewart J. Sensitization occurs to the locomotor effects of morphine and the specific mu opioid receptor agonist, DAGO, administered repeatedly to the ventral tegmental area but not to the nucleus accumbens. Brain Res. 417:1987;51-58.
55. Yukhananov R.Y., Handa R.J. Effect of morphine on proenkephalin gene expression in the rat brain. Brain Res. Bull. 43:1997;349-356.
56. K. Zilles, A. Wree, Cortex: areal and laminar structure, in: G. Paxinos (Ed.), The Rat Nervous System, 2nd edn., Academic Press, San Diego, 1995, pp. 649-685.