Relationship between seizure-induced transcription of the DNA damage- inducible gene GADD45, DNA fragmentation, and neuronal death in focally evoked limbic epilepsy

Journal of Neurochemistry

Volumn 73, Issue 4, 1999, Pages 1573-1583

  Henshall, David C ^a   Sinclair, Jennifer ^a   Simon, Roger P ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

DNA damage; Electroencephalography; GADD45; Klenow fragment; Rat; Seizure

Indexed keywords

DNA FRAGMENT; GENE PRODUCT; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; MESSENGER RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; COMPLEX PARTIAL SEIZURE; CONTROLLED STUDY; DNA DAMAGE; ELECTROENCEPHALOGRAM; GENETIC TRANSCRIPTION; LIMBIC SYSTEM; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT;

AMYGDALA; ANIMALS; BRAIN; CEREBRAL CORTEX; DNA DAMAGE; DNA FRAGMENTATION; ELECTROENCEPHALOGRAPHY; EPILEPSIES, PARTIAL; FUNCTIONAL LATERALITY; HIPPOCAMPUS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KAINIC ACID; LIMBIC SYSTEM; MALE; MICROINJECTIONS; NEURONS; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; SEIZURES; THALAMUS;

EID: 0032842207     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.0731573.x     Document Type: Article

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