In situ detection of neuronal DNA strand breaks using the Klenow fragment of DNA polymerase I reveals different mechanisms of neuron death after global cerebral ischemia

Journal of Neurochemistry

Volumn 72, Issue 3, 1999, Pages 1204-1214

  Jin, Kunlin ^a   Chen, Jun ^a   Nagayama, Tetsuya ^a   Chen, Minzhi ^a   Sinclair, Jennifer ^a   Graham, Steven H ^a   Simon, Roger P ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Brain; DNA strand breaks; Ischemia; Klenow fragment Terminal deoxynucleotidyl transferase; Terminal deoxynucleotidyl transferase mediated dUTP nick end labeling

Indexed keywords

DNA DIRECTED DNA POLYMERASE BETA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN ISCHEMIA; CAUDATE NUCLEUS; CELL DAMAGE; DNA DAMAGE; DNA STRAND BREAKAGE; NERVE CELL DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PUTAMEN; RAT; RETICULAR FORMATION; THALAMUS;

ANIMALS; APOPTOSIS; BRAIN; BRAIN ISCHEMIA; CELL COUNT; DNA DAMAGE; DNA POLYMERASE I; IN SITU NICK-END LABELING; MALE; NEURONS; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 0033048622     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.0721204.x     Document Type: Article

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