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Volumn 237, Issue 2, 1999, Pages 303-310

Ribozymes and the anti-gene therapy: How a catalytic RNA can be used to inhibit gene function

Author keywords

Catalytic RNA; Gene inhibition; Ribozymes

Indexed keywords

RIBOZYME;

EID: 0032833304     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(99)00334-0     Document Type: Review
Times cited : (35)

References (93)
  • 1
    • 0032580348 scopus 로고    scopus 로고
    • Human gene therapy
    • Anderson W.F. Human gene therapy. Nature. 392:1998;25-30.
    • (1998) Nature , vol.392 , pp. 25-30
    • Anderson, W.F.1
  • 2
    • 0031423677 scopus 로고    scopus 로고
    • Colocalization of antisense RNAs and ribozymes with their target mRNAs
    • Arndt G.M., Rank G.H. Colocalization of antisense RNAs and ribozymes with their target mRNAs. Genome. 40:1997;785-797.
    • (1997) Genome , vol.40 , pp. 785-797
    • Arndt, G.M.1    Rank, G.H.2
  • 3
    • 0030047819 scopus 로고    scopus 로고
    • HIV-1 reverse transcriptase and early events in reverse transcription
    • Arts E.J., Wainberg M.A. HIV-1 reverse transcriptase and early events in reverse transcription. Adv. Virus Res. 46:1996;97-163.
    • (1996) Adv. Virus Res. , vol.46 , pp. 97-163
    • Arts, E.J.1    Wainberg, M.A.2
  • 4
    • 0030935630 scopus 로고    scopus 로고
    • Inhibition of human immunodeficiency virus-1 (HIV-1) replication after transduction of granulocyte colony-stimulating factor-mobilized CD34(+) cells from HIV-1-infected donors using retroviral vectors containing anti-HIV-1 genes
    • Bauer G., Valdez P., Kearns K., Bahner I., Wen S.F., Zaia J.A., Kohn D.B. Inhibition of human immunodeficiency virus-1 (HIV-1) replication after transduction of granulocyte colony-stimulating factor-mobilized CD34(+) cells from HIV-1-infected donors using retroviral vectors containing anti-HIV-1 genes. Blood. 89:1997;2259-2267.
    • (1997) Blood , vol.89 , pp. 2259-2267
    • Bauer, G.1    Valdez, P.2    Kearns, K.3    Bahner, I.4    Wen, S.F.5    Zaia, J.A.6    Kohn, D.B.7
  • 5
    • 0029586990 scopus 로고
    • Efficient hammerhead ribozyme-mediated cleavage of the structured hepatitis B virus encapsidations signal in vitro and in cell extracts, but not in intact cells
    • Beck J., Nassal M. Efficient hammerhead ribozyme-mediated cleavage of the structured hepatitis B virus encapsidations signal in vitro and in cell extracts, but not in intact cells. Nucleic Acids Res. 23:1995;4954-4962.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 4954-4962
    • Beck, J.1    Nassal, M.2
  • 6
    • 0344338368 scopus 로고
    • Gene gating: A hypothesis
    • Blobel G. Gene gating: a hypothesis. Proc. Natl. Acad. Sci. USA. 82:1995;8527-8529.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 8527-8529
    • Blobel, G.1
  • 7
    • 0028675028 scopus 로고
    • A DNA enzyme that cleaves RNA
    • Breaker R.R., Joyce G.F. A DNA enzyme that cleaves RNA. Chem. Biol. 1:1994;223-229.
    • (1994) Chem. Biol. , vol.1 , pp. 223-229
    • Breaker, R.R.1    Joyce, G.F.2
  • 8
    • 0027973658 scopus 로고
    • Structure-mapping of the hairpin ribozyme. Magnesium-dependent folding and evidence for tertiary interactions within the ribozyme-substrate complex
    • Butcher S.E., Burke J.M. Structure-mapping of the hairpin ribozyme. Magnesium-dependent folding and evidence for tertiary interactions within the ribozyme-substrate complex. J. Mol. Biol. 244:1994;52-63.
    • (1994) J. Mol. Biol. , vol.244 , pp. 52-63
    • Butcher, S.E.1    Burke, J.M.2
  • 10
    • 0028395411 scopus 로고
    • Target gene replacement
    • Capecchi M.R. Target gene replacement. Sci. Am. 270:1994;52-59.
    • (1994) Sci. Am. , vol.270 , pp. 52-59
    • Capecchi, M.R.1
  • 11
    • 0019856947 scopus 로고
    • In vitro splicing of the ribosomal RNA precursor of Tetrahymena: Involvement of a guanosine nucleotide in the excision of the intervening sequence
    • Cech T.R., Zaug A.J., Grabowski P.J. In vitro splicing of the ribosomal RNA precursor of Tetrahymena: involvement of a guanosine nucleotide in the excision of the intervening sequence. Cell. 27:1981;487-496.
    • (1981) Cell , vol.27 , pp. 487-496
    • Cech, T.R.1    Zaug, A.J.2    Grabowski, P.J.3
  • 12
    • 0028676217 scopus 로고
    • TKO'ed: Lox, stock and barrel
    • Chambers C.A. TKO'ed: lox, stock and barrel. Bioessays. 16:1994;865-868.
    • (1994) Bioessays , vol.16 , pp. 865-868
    • Chambers, C.A.1
  • 13
    • 0030902414 scopus 로고    scopus 로고
    • Triplex DNA: Fundamentals, advances and potential applications for gene therapy
    • Chan P.P., Glazer P.M. Triplex DNA: fundamentals, advances and potential applications for gene therapy. J. Mol. Med. 75:1997;267-282.
    • (1997) J. Mol. Med. , vol.75 , pp. 267-282
    • Chan, P.P.1    Glazer, P.M.2
  • 14
    • 0031046717 scopus 로고    scopus 로고
    • A ribozyme specifically suppresses transformation and tumorigenicity of Ha-ras-oncogene-transformed NIH/3T3 cell lines
    • Chang M.Y., Won S.J., Liu H.S. A ribozyme specifically suppresses transformation and tumorigenicity of Ha-ras-oncogene-transformed NIH/3T3 cell lines. J. Cancer Res. Clin. Oncol. 123:1997;91-99.
    • (1997) J. Cancer Res. Clin. Oncol. , vol.123 , pp. 91-99
    • Chang, M.Y.1    Won, S.J.2    Liu, H.S.3
  • 15
    • 0026779558 scopus 로고
    • Multitarget-ribozyme directed to cleave at up to nine highly conserved HIV-1 env RNA regions inhibits HIV-1 replication-potencial effectiveness against most presently sequenced HIV-1 isolates
    • Chen C.J., Banerjea A.C., Harmion G.G., Haglund K., Schubert M. Multitarget-ribozyme directed to cleave at up to nine highly conserved HIV-1 env RNA regions inhibits HIV-1 replication-potencial effectiveness against most presently sequenced HIV-1 isolates. Nucleic Acids Res. 20:1992;4581-4589.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 4581-4589
    • Chen, C.J.1    Banerjea, A.C.2    Harmion, G.G.3    Haglund, K.4    Schubert, M.5
  • 16
    • 0029436666 scopus 로고
    • Effectiveness of three ribozymes for cleavage of an RNA transcript from human papillomavirus type 18
    • Chen Z., Kamath P., Zhang S., Weil M.M., Shillitoe E.J. Effectiveness of three ribozymes for cleavage of an RNA transcript from human papillomavirus type 18. Cancer Gene Ther. 2:1995;263-271.
    • (1995) Cancer Gene Ther. , vol.2 , pp. 263-271
    • Chen, Z.1    Kamath, P.2    Zhang, S.3    Weil, M.M.4    Shillitoe, E.J.5
  • 17
    • 0029037713 scopus 로고
    • A DNA metalloenzyme with DNA ligase activity
    • Cuenoud B., Szostak J.W. A DNA metalloenzyme with DNA ligase activity. Nature. 375:1995;611-614.
    • (1995) Nature , vol.375 , pp. 611-614
    • Cuenoud, B.1    Szostak, J.W.2
  • 18
    • 0025998488 scopus 로고
    • Role of divalent metal ions in the hammerhead RNA cleavage reaction
    • Dahm S.C., Uhlenbeck O.C. Role of divalent metal ions in the hammerhead RNA cleavage reaction. Biochemistry. 30:1991;9464-9469.
    • (1991) Biochemistry , vol.30 , pp. 9464-9469
    • Dahm, S.C.1    Uhlenbeck, O.C.2
  • 19
    • 0027674382 scopus 로고
    • Localized RNAs and their functions
    • Ding D., Lipshitz H.D. Localized RNAs and their functions. Bioessays. 15:1993;651-658.
    • (1993) Bioessays , vol.15 , pp. 651-658
    • Ding, D.1    Lipshitz, H.D.2
  • 20
    • 0030822629 scopus 로고    scopus 로고
    • Development of a hammerhead ribozyme against bcl-2. I. Preliminary evaluation of a potential gene therapeutic agent for hormone-refractory human prostate cancer
    • Dorai T., Olsson C.A., Katz A.E., Buttyan P. Development of a hammerhead ribozyme against bcl-2. I. Preliminary evaluation of a potential gene therapeutic agent for hormone-refractory human prostate cancer. Prostate. 32:1997;246-258.
    • (1997) Prostate , vol.32 , pp. 246-258
    • Dorai, T.1    Olsson, C.A.2    Katz, A.E.3    Buttyan, P.4
  • 21
    • 0030856993 scopus 로고    scopus 로고
    • Intracellular inhibition of HIV-1 replication using a dual protein- And RNA-based strategy
    • published corrigendum appears in Gene Ther. 5 (1998) 570
    • Duan L., Zhu D., Ozaki I., Zhang H., Wei D.L., Pomerantz R.J. Intracellular inhibition of HIV-1 replication using a dual protein- and RNA-based strategy. Gene Ther. 4:1997;533-543. published corrigendum appears in Gene Ther. 5 (1998) 570.
    • (1997) Gene Ther. , vol.4 , pp. 533-543
    • Duan, L.1    Zhu, D.2    Ozaki, I.3    Zhang, H.4    Wei, D.L.5    Pomerantz, R.J.6
  • 22
    • 0032534533 scopus 로고    scopus 로고
    • Hairpin ribozyme cleavage catalyzed by aminoglycoside antibiotics and the polyamine spermine in the absence of metal ions
    • Earnshaw D.J., Gait M.J. Hairpin ribozyme cleavage catalyzed by aminoglycoside antibiotics and the polyamine spermine in the absence of metal ions. Nucleic Acids Res. 26:1998;5551-5561.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 5551-5561
    • Earnshaw, D.J.1    Gait, M.J.2
  • 23
    • 0029093855 scopus 로고
    • The secondary structure and sequence optimisation of an RNA ligase ribozyme
    • Ekland E.H., Bartel D.P. The secondary structure and sequence optimisation of an RNA ligase ribozyme. Nucleic Acids Res. 23:1995;3231-3238.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 3231-3238
    • Ekland, E.H.1    Bartel, D.P.2
  • 24
    • 0026620322 scopus 로고
    • Kinetics of intermolecular cleavage by hammerhead ribozymes
    • Fedor M.J., Uhlenbeck O.C. Kinetics of intermolecular cleavage by hammerhead ribozymes. Biochemistry. 31:1992;12042-12054.
    • (1992) Biochemistry , vol.31 , pp. 12042-12054
    • Fedor, M.J.1    Uhlenbeck, O.C.2
  • 25
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranted RNA in Caenorhabditis elegans
    • Fire A., Xu S., Montgomery M.K., Kostas S.A., Driver S.E., Mello C.C. Potent and specific genetic interference by double-stranted RNA in Caenorhabditis elegans. Nature. 391:1998;806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 27
    • 0026664707 scopus 로고
    • Enhancement of ribozyme catalytic activity by a contiguous oligodeoxynucleotide (facilitator) and by 2′-O-methylation
    • Goodchild J. Enhancement of ribozyme catalytic activity by a contiguous oligodeoxynucleotide (facilitator) and by 2′-O-methylation. Nucleic Acids Res. 20:1992;4607-4612.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 4607-4612
    • Goodchild, J.1
  • 28
    • 0021332087 scopus 로고
    • Catalytic activity of an RNA molecule prepared by transcription in vitro
    • Guerrier T., Altman S. Catalytic activity of an RNA molecule prepared by transcription in vitro. Science. 223:1984;285-286.
    • (1984) Science , vol.223 , pp. 285-286
    • Guerrier, T.1    Altman, S.2
  • 29
    • 0029024475 scopus 로고
    • Par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed
    • Guo S., Kemphues K.J. Par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed. Cell. 81:1995;611-620.
    • (1995) Cell , vol.81 , pp. 611-620
    • Guo, S.1    Kemphues, K.J.2
  • 30
    • 0031961687 scopus 로고    scopus 로고
    • The Hairpin ribozyme: Discovery, two-dimensional model, and development for gene therapy
    • Hampel A. The Hairpin ribozyme: discovery, two-dimensional model, and development for gene therapy. Progr. Nucleic Acid Res. Mol. Biol. 58:1998;1-39.
    • (1998) Progr. Nucleic Acid Res. Mol. Biol. , vol.58 , pp. 1-39
    • Hampel, A.1
  • 31
    • 0027955448 scopus 로고
    • High activity and stability of hammerhead ribozymes containing 2′-modified pyrimidine necleosides and phosphorothioates
    • Heidenreich O., Benseler F., Fahrenholz A., Eckstein F. High activity and stability of hammerhead ribozymes containing 2′-modified pyrimidine necleosides and phosphorothioates. J. Biol. Chem. 269:1994;2131-2138.
    • (1994) J. Biol. Chem. , vol.269 , pp. 2131-2138
    • Heidenreich, O.1    Benseler, F.2    Fahrenholz, A.3    Eckstein, F.4
  • 32
    • 0028288686 scopus 로고
    • A kinetic and thermodynamic framework for the hammerhead ribozyme reaction
    • Hertel K.J., Herschlag D., Uhlenbeck O.C. A kinetic and thermodynamic framework for the hammerhead ribozyme reaction. Biochemistry. 33:1994;3374-3385.
    • (1994) Biochemistry , vol.33 , pp. 3374-3385
    • Hertel, K.J.1    Herschlag, D.2    Uhlenbeck, O.C.3
  • 33
    • 0032559057 scopus 로고    scopus 로고
    • 2+ binding affinities to the hammerhead ribozyme and correlation with cleavage activity
    • 2+ binding affinities to the hammerhead ribozyme and correlation with cleavage activity. Biochemistry. 37:1998;18094-18101.
    • (1998) Biochemistry , vol.37 , pp. 18094-18101
    • Horton, T.E.1    Clardy, D.R.2    Derose, V.J.3
  • 34
    • 0026683694 scopus 로고
    • Delta virus as a vector for the delivery of biologically-active RNAs: Possibly a ribozyme specific for chronic hepatitis B virus infection
    • Hsieh S.Y., Taylor J. Delta virus as a vector for the delivery of biologically-active RNAs: possibly a ribozyme specific for chronic hepatitis B virus infection. Adv. Exp. Med. Biol. 312:1992;125-128.
    • (1992) Adv. Exp. Med. Biol. , vol.312 , pp. 125-128
    • Hsieh, S.Y.1    Taylor, J.2
  • 35
    • 0029143916 scopus 로고
    • Isolation of active ribozymes from an RNA pool of random sequences using an anchored substrate RNA
    • Ishizaka M., Ohshima Y., Tani T. Isolation of active ribozymes from an RNA pool of random sequences using an anchored substrate RNA. Biochem. Biophys. Res. Commun. 214:1995;403-409.
    • (1995) Biochem. Biophys. Res. Commun. , vol.214 , pp. 403-409
    • Ishizaka, M.1    Ohshima, Y.2    Tani, T.3
  • 37
    • 0030996755 scopus 로고    scopus 로고
    • The new world of ribozymes
    • Jaeger L. The new world of ribozymes. Curr. Opin. Struct. Biol. 7:1997;324-335.
    • (1997) Curr. Opin. Struct. Biol. , vol.7 , pp. 324-335
    • Jaeger, L.1
  • 38
    • 0028907049 scopus 로고
    • Ribozymes: Biology, biochemistry, and implications for clinical medicine
    • Kiehntopf M., Esquivel E.L., Brach M.A., Herrmann R. Ribozymes: biology, biochemistry, and implications for clinical medicine. J. Mol. Med. 73:1995;65-71.
    • (1995) J. Mol. Med. , vol.73 , pp. 65-71
    • Kiehntopf, M.1    Esquivel, E.L.2    Brach, M.A.3    Herrmann, R.4
  • 40
    • 0026653293 scopus 로고
    • Ribozymes designed to inhibit transformation of NIH/3T3 cells by the activated c-Ha-ras gene
    • Koizumi M., Kamiya H., Ohtsuka E. Ribozymes designed to inhibit transformation of NIH/3T3 cells by the activated c-Ha-ras gene. Gene. 117:1992;179-184.
    • (1992) Gene , vol.117 , pp. 179-184
    • Koizumi, M.1    Kamiya, H.2    Ohtsuka, E.3
  • 42
    • 0022497718 scopus 로고
    • Intracellular localization of messenger RNAs for cytoskeletal proteins
    • Lawrence J.B., Singer R.H. Intracellular localization of messenger RNAs for cytoskeletal proteins. Cell. 45:1986;407-415.
    • (1986) Cell , vol.45 , pp. 407-415
    • Lawrence, J.B.1    Singer, R.H.2
  • 44
    • 0031934753 scopus 로고    scopus 로고
    • Gene therapy targeting cord blood-derived CD34+ cells from HIV-exposed infants: Preclinical studies
    • Li A., Gervaix A., Kang D., Law P., Spector S.A., Ho A.D., Wong-Staal F. Gene therapy targeting cord blood-derived CD34+ cells from HIV-exposed infants: preclinical studies. Gene Ther. 5:1998;233-239.
    • (1998) Gene Ther. , vol.5 , pp. 233-239
    • Li, A.1    Gervaix, A.2    Kang, D.3    Law, P.4    Spector, S.A.5    Ho, A.D.6    Wong-Staal, F.7
  • 45
    • 0033150946 scopus 로고    scopus 로고
    • Deoxyribozymes: New players in the ancient game of biocatalysis
    • Li Y., Breaker R.R. Deoxyribozymes: new players in the ancient game of biocatalysis. Curr. Opin. Struct. Biol. 9:1999;315-323.
    • (1999) Curr. Opin. Struct. Biol. , vol.9 , pp. 315-323
    • Li, Y.1    Breaker, R.R.2
  • 46
    • 0029970824 scopus 로고    scopus 로고
    • Elimination of hepatitis C virus RNA in infected human hepatocytes by adenovirus-mediated expression of ribozymes
    • Lieber A., He C.Y., Polyak S.J., Gretch D.R., Barr D., Kay M.A. Elimination of hepatitis C virus RNA in infected human hepatocytes by adenovirus-mediated expression of ribozymes. J. Virol. 70:1996;8782-8791.
    • (1996) J. Virol. , vol.70 , pp. 8782-8791
    • Lieber, A.1    He, C.Y.2    Polyak, S.J.3    Gretch, D.R.4    Barr, D.5    Kay, M.A.6
  • 47
    • 0026785305 scopus 로고
    • Inhibition of replication of HIV-1 by retroviral vectors expressing tat-antisense and anti-tat ribozyme RNA
    • Lo K.M., Biasolo M.A., Dhni G., Palu G., Haseltine W.A. Inhibition of replication of HIV-1 by retroviral vectors expressing tat-antisense and anti-tat ribozyme RNA. Virology. 190:1992;176-183.
    • (1992) Virology , vol.190 , pp. 176-183
    • Lo, K.M.1    Biasolo, M.A.2    Dhni, G.3    Palu, G.4    Haseltine, W.A.5
  • 48
    • 0028700483 scopus 로고
    • Ribozyme-mediated in vitro cleavage of transcripts arising from the major transforming genes of human papillomavirus type 16
    • Lu D., Chatterjel S., Bran D., Wong K.K. Jr. Ribozyme-mediated in vitro cleavage of transcripts arising from the major transforming genes of human papillomavirus type 16. Cancer Gene Ther. 1:1994;267-277.
    • (1994) Cancer Gene Ther. , vol.1 , pp. 267-277
    • Lu, D.1    Chatterjel, S.2    Bran, D.3    Wong K.K., Jr.4
  • 49
    • 0028527570 scopus 로고
    • Inhibition of viral multiplication by hammerhead ribozymes targeted against the polymerase gene of mouse hepatitis virus
    • Maeda A., Mizutani T., Hayashi M., Watanabe T., Namioka S. Inhibition of viral multiplication by hammerhead ribozymes targeted against the polymerase gene of mouse hepatitis virus. J. Vet. Med. Sci. 56:1994;939-945.
    • (1994) J. Vet. Med. Sci. , vol.56 , pp. 939-945
    • Maeda, A.1    Mizutani, T.2    Hayashi, M.3    Watanabe, T.4    Namioka, S.5
  • 50
    • 0029319691 scopus 로고
    • Inhibition of viral multiplication in cells chronically infected with mouse hepatitis virus by antisense RNA against the polymerase gene
    • Maeda A., Hayashi M., Mizutani T., Ishida K., Watanabe T., Namioka S. Inhibition of viral multiplication in cells chronically infected with mouse hepatitis virus by antisense RNA against the polymerase gene. J. Vet. Med. Sci. 57:1995;563-565.
    • (1995) J. Vet. Med. Sci. , vol.57 , pp. 563-565
    • Maeda, A.1    Hayashi, M.2    Mizutani, T.3    Ishida, K.4    Watanabe, T.5    Namioka, S.6
  • 51
    • 0025892665 scopus 로고
    • Hepatitis B: Evolving epidemiology and implications for control
    • Margolis H.S., Alter M.J., Hadler S.C. Hepatitis B: evolving epidemiology and implications for control. Semin. Liver Dis. 11:1991;84-92.
    • (1991) Semin. Liver Dis. , vol.11 , pp. 84-92
    • Margolis, H.S.1    Alter, M.J.2    Hadler, S.C.3
  • 52
    • 0028209388 scopus 로고
    • Inhibition of mouse hepatitis virus multiplication by antisense oligonucleotide, antisense RNA, sense RNA and ribozyme
    • Mizutani T., Hayashi M., Maeda A., Sasaki N., Yamashita T., Kasai N., Namioka S. Inhibition of mouse hepatitis virus multiplication by antisense oligonucleotide, antisense RNA, sense RNA and ribozyme. Adv. Exp. Med. Biol. 342:1993;129-135.
    • (1993) Adv. Exp. Med. Biol. , vol.342 , pp. 129-135
    • Mizutani, T.1    Hayashi, M.2    Maeda, A.3    Sasaki, N.4    Yamashita, T.5    Kasai, N.6    Namioka, S.7
  • 53
    • 0030899989 scopus 로고    scopus 로고
    • Inhibition of fibrilin-1 expression using U1 snRNA as a vehicle for the presentation of antisense targeting sequence
    • Montgomery R.A., Dietz H.C. Inhibition of fibrilin-1 expression using U1 snRNA as a vehicle for the presentation of antisense targeting sequence. Hum. Mol. Genet. 6:1997;519-525.
    • (1997) Hum. Mol. Genet. , vol.6 , pp. 519-525
    • Montgomery, R.A.1    Dietz, H.C.2
  • 54
    • 0027346096 scopus 로고
    • Modified HDV as a vector for the delivery of biologically-active RNAs
    • Netter H.J., Hsieh S.Y., Lazinski D., Taylor J. Modified HDV as a vector for the delivery of biologically-active RNAs. Prog. Clin. Biol. Res. 282:1993;373-376.
    • (1993) Prog. Clin. Biol. Res. , vol.282 , pp. 373-376
    • Netter, H.J.1    Hsieh, S.Y.2    Lazinski, D.3    Taylor, J.4
  • 55
  • 56
    • 0026529507 scopus 로고
    • Nuclease resistant ribozymes with high catalytic activity
    • Paolella G., Sproat B., Lamond A.I. Nuclease resistant ribozymes with high catalytic activity. EMBO J. 11:1992;1913-1919.
    • (1992) EMBO J. , vol.11 , pp. 1913-1919
    • Paolella, G.1    Sproat, B.2    Lamond, A.I.3
  • 57
    • 0031225829 scopus 로고    scopus 로고
    • Ribozyme therapeutics
    • Persidis A. Ribozyme therapeutics. Nature Biotechnol. 15:1997;921-922.
    • (1997) Nature Biotechnol. , vol.15 , pp. 921-922
    • Persidis, A.1
  • 59
    • 0026337408 scopus 로고
    • Kinetic characterization of ribonuclease resistan 2′-modified hammerhead ribozymes
    • Pieken W.W.A., Olsen D.B., Banseler F., Aurup H., Eckstein F. Kinetic characterization of ribonuclease resistan 2′-modified hammerhead ribozymes. Science. 253:1991;314-317.
    • (1991) Science , vol.253 , pp. 314-317
    • Pieken, W.W.A.1    Olsen, D.B.2    Banseler, F.3    Aurup, H.4    Eckstein, F.5
  • 60
    • 0028781381 scopus 로고
    • DNA Triplex: Solution Structures, Hydration Sites, Energies, Interactions and Functions
    • Radhakrishnan I., Patel D. DNA Triplex: Solution Structures, Hydration Sites, Energies, Interactions and Functions. Biochemistry. 33:1994;11405-11416.
    • (1994) Biochemistry , vol.33 , pp. 11405-11416
    • Radhakrishnan, I.1    Patel, D.2
  • 61
    • 0030775529 scopus 로고    scopus 로고
    • Inhibition of HIV-1 replication by retroviral vectors expressing monomeric and multimeric hammerhead ribozymes
    • Ramezani A., Ding S.F., Joshi S. Inhibition of HIV-1 replication by retroviral vectors expressing monomeric and multimeric hammerhead ribozymes. Gene Ther. 4:1997;861-867.
    • (1997) Gene Ther. , vol.4 , pp. 861-867
    • Ramezani, A.1    Ding, S.F.2    Joshi, S.3
  • 63
    • 0030481468 scopus 로고    scopus 로고
    • Intracellular cleavage of hepatitis C virus RNA and inhibition of viral protein translation by hammerhead ribozymes
    • Sakamoto N., Wu C.H., Wu G.Y. Intracellular cleavage of hepatitis C virus RNA and inhibition of viral protein translation by hammerhead ribozymes. J. Clin. Invest. 98:1996;2720-2728.
    • (1996) J. Clin. Invest. , vol.98 , pp. 2720-2728
    • Sakamoto, N.1    Wu, C.H.2    Wu, G.Y.3
  • 65
    • 0024041732 scopus 로고
    • Site-specific recombination in mammalian cells by the Cre recombinase of bacteriophage P1
    • Sauer B., Henderson N. Site-specific recombination in mammalian cells by the Cre recombinase of bacteriophage P1. Proc. Natl. Acad. Sci. USA. 85:1988;5166-5170.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 5166-5170
    • Sauer, B.1    Henderson, N.2
  • 66
    • 0025872121 scopus 로고
    • Ribozyme-mediated cleavage of c-fos mRNA reduces gene expression of DNA synthesis enzymes and metallothionein
    • Scanlon K., Jiao L., Funato T., Wang W., Tone T., Rossi J.J., Kashani S.M. Ribozyme-mediated cleavage of c-fos mRNA reduces gene expression of DNA synthesis enzymes and metallothionein. Proc. Natl. Acad. Sci. USA. 88:1991;10591-10595.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 10591-10595
    • Scanlon, K.1    Jiao, L.2    Funato, T.3    Wang, W.4    Tone, T.5    Rossi, J.J.6    Kashani, S.M.7
  • 67
    • 0027227872 scopus 로고
    • Nuclease resistant chimeric ribozymes containing deoxyribonucleotide and phosphorothioate linkages
    • Shimayama T., Nishikawa F., Nishikawa S., Kazunasi T. Nuclease resistant chimeric ribozymes containing deoxyribonucleotide and phosphorothioate linkages. Nucleic Acids Res. 21:1993;2605-2611.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 2605-2611
    • Shimayama, T.1    Nishikawa, F.2    Nishikawa, S.3    Kazunasi, T.4
  • 68
    • 0026513691 scopus 로고
    • Preformed ribozyme destroys tumor necrosis factor in RNA in human cells
    • Sioud M., Natuig J.B., Forre O. Preformed ribozyme destroys tumor necrosis factor in RNA in human cells. J. Mol. Biol. 223:1992;831-835.
    • (1992) J. Mol. Biol. , vol.223 , pp. 831-835
    • Sioud, M.1    Natuig, J.B.2    Forre, O.3
  • 69
    • 0027218359 scopus 로고
    • Ribozyme-mediated inhibition of bcl-abl gene expression in a Philadelphia chromosome-positive cell line
    • Snyder D.S., Wu Y., Wang J.L., Rossi J.J., Swiderski P., Kaplan B.E., Forman S.J. Ribozyme-mediated inhibition of bcl-abl gene expression in a Philadelphia chromosome-positive cell line. Blood. 82:1993;600-605.
    • (1993) Blood , vol.82 , pp. 600-605
    • Snyder, D.S.1    Wu, Y.2    Wang, J.L.3    Rossi, J.J.4    Swiderski, P.5    Kaplan, B.E.6    Forman, S.J.7
  • 70
    • 0003471941 scopus 로고
    • N. Sperelakis. New York: Academic Press
    • Sperelakis N. Cell Physiology Source Book. 1995;Academic Press, New York.
    • (1995) Cell Physiology Source Book
  • 72
    • 0028806487 scopus 로고
    • Does antisense exist?
    • Stein C.A. Does antisense exist? Nat. Med. 1:1995;1119-1121.
    • (1995) Nat. Med. , vol.1 , pp. 1119-1121
    • Stein, C.A.1
  • 73
    • 0027742736 scopus 로고
    • Tethering ribozymes to a retroviral packaging signal for destruction of viral RNA
    • Sullenger B.A., Cech T.R. Tethering ribozymes to a retroviral packaging signal for destruction of viral RNA. Science. 262:1993;1566-1568.
    • (1993) Science , vol.262 , pp. 1566-1568
    • Sullenger, B.A.1    Cech, T.R.2
  • 75
    • 0026651086 scopus 로고
    • Small catalytic RNAs
    • Symons R.H. Small catalytic RNAs. Annu. Ver. Biochem. 61:1992;641-671.
    • (1992) Annu. Ver. Biochem. , vol.61 , pp. 641-671
    • Symons, R.H.1
  • 76
    • 0032538391 scopus 로고    scopus 로고
    • RNAi in C.elegans: Soaking in the genome sequence
    • Tabara H., Grishok A., Mello C.C. RNAi in C.elegans: soaking in the genome sequence. Science. 282:1998;430-431.
    • (1998) Science , vol.282 , pp. 430-431
    • Tabara, H.1    Grishok, A.2    Mello, C.C.3
  • 77
    • 0028286815 scopus 로고
    • Ribozyme mediated destruction of influenza A virus in vitro and in vivo
    • Tang X.B., Hobom G., Luo D. Ribozyme mediated destruction of influenza A virus in vitro and in vivo. J. Med. Virol. 42:1994;385-395.
    • (1994) J. Med. Virol. , vol.42 , pp. 385-395
    • Tang, X.B.1    Hobom, G.2    Luo, D.3
  • 78
    • 0026672823 scopus 로고
    • Chimeric DNA-RNA hammerhead ribozymes have enhanced in vivo catalytic efficiency and increased stability in vivo
    • Taylor N.R., Kaplan B.A., Swiderski P., Li H., Rossi J.J. Chimeric DNA-RNA hammerhead ribozymes have enhanced in vivo catalytic efficiency and increased stability in vivo. Nucleic Acids Res. 20:1992;4559-4565.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 4559-4565
    • Taylor, N.R.1    Kaplan, B.A.2    Swiderski, P.3    Li, H.4    Rossi, J.J.5
  • 80
    • 0023221419 scopus 로고
    • A small catalytic oligoribonucleotide
    • Uhlenbeck O.C. A small catalytic oligoribonucleotide. Nature. 328:1987;596-600.
    • (1987) Nature , vol.328 , pp. 596-600
    • Uhlenbeck, O.C.1
  • 81
    • 11944267365 scopus 로고
    • Antisense oligonucleotides: A new therapeutic principle
    • Uhlmann E., Peymann A. Antisense oligonucleotides: a new therapeutic principle. Chem. Rev. 90:1990;543-584.
    • (1990) Chem. Rev. , vol.90 , pp. 543-584
    • Uhlmann, E.1    Peymann, A.2
  • 82
    • 0030928619 scopus 로고    scopus 로고
    • Gene therapy-promises, problems and prospects
    • Verma I.M., Somia N. Gene therapy-promises, problems and prospects. Nature. 389:1997;239-242.
    • (1997) Nature , vol.389 , pp. 239-242
    • Verma, I.M.1    Somia, N.2
  • 83
    • 0029144892 scopus 로고
    • Toward a broad-based antisense technology
    • Wagner R.W. Toward a broad-based antisense technology. Antisense Res. Dev. 5:1995;113-114.
    • (1995) Antisense Res. Dev. , vol.5 , pp. 113-114
    • Wagner, R.W.1
  • 84
    • 0032578623 scopus 로고    scopus 로고
    • Novel configurations of the hammerhead ribozyme: Increased activity and reduced magnesium ion requirement
    • Wang L., Ruffner D.E. Novel configurations of the hammerhead ribozyme: Increased activity and reduced magnesium ion requirement. Biochem. Biophys. Res. Commun. 250:1998;711-719.
    • (1998) Biochem. Biophys. Res. Commun. , vol.250 , pp. 711-719
    • Wang, L.1    Ruffner, D.E.2
  • 85
    • 0029972264 scopus 로고    scopus 로고
    • A potential therapeutic applications of hairpin ribozymes: In vitro and in vivo studies of gene therapy for hepatitis C virus infection
    • Welch P.J., Tritz R., Yei S., Leavitt M., Yu M., Barber J. A potential therapeutic applications of hairpin ribozymes: In vitro and in vivo studies of gene therapy for hepatitis C virus infection. Gene Ther. 3:1996;994-1001.
    • (1996) Gene Ther. , vol.3 , pp. 994-1001
    • Welch, P.J.1    Tritz, R.2    Yei, S.3    Leavitt, M.4    Yu, M.5    Barber, J.6
  • 86
    • 0030743739 scopus 로고    scopus 로고
    • Intracellular application of hairpin ribozyme genes against hepatitis B virus
    • Welch P.J., Tritz R., Yei S., Barber J., Yu M. Intracellular application of hairpin ribozyme genes against hepatitis B virus. Gene Ther. 4:1997;736-743.
    • (1997) Gene Ther. , vol.4 , pp. 736-743
    • Welch, P.J.1    Tritz, R.2    Yei, S.3    Barber, J.4    Yu, M.5
  • 87
    • 0032211255 scopus 로고    scopus 로고
    • A controlled, Phase 1 clinical trial to evaluate the safety and effects in HIV-1 infected humans of autologous lymphocytes transduced with a ribozyme that cleaves HIV-1 RNA
    • Wong-Staal F., Poeschla E.M., Looney D.J. A controlled, Phase 1 clinical trial to evaluate the safety and effects in HIV-1 infected humans of autologous lymphocytes transduced with a ribozyme that cleaves HIV-1 RNA. Hum. Gene Ther. 9:1998;2407-2425.
    • (1998) Hum. Gene Ther. , vol.9 , pp. 2407-2425
    • Wong-Staal, F.1    Poeschla, E.M.2    Looney, D.J.3
  • 88
    • 0028051280 scopus 로고
    • Intracellular immunization of human T-cells with a hairpin ribozyme against human immunodeficiency virus type 1
    • Yamada O., Yu M., Yee J.K., Kraus G., Looney D., Wong-Staal F. Intracellular immunization of human T-cells with a hairpin ribozyme against human immunodeficiency virus type 1. Gene Ther. 1:1994;38-45.
    • (1994) Gene Ther. , vol.1 , pp. 38-45
    • Yamada, O.1    Yu, M.2    Yee, J.K.3    Kraus, G.4    Looney, D.5    Wong-Staal, F.6
  • 89
    • 0030051703 scopus 로고    scopus 로고
    • A chimeric human immunodeficiency virus type 1 (HIV-1) minimal Rev response element-ribozyme molecule exhibits dual antiviral function and inhibits cell-cell transmission of HIV-1
    • Yamada O., Kraus G., Luznik L., Yu M., Wong-Staal F. A chimeric human immunodeficiency virus type 1 (HIV-1) minimal Rev response element-ribozyme molecule exhibits dual antiviral function and inhibits cell-cell transmission of HIV-1. J. Virol. 70:1996;1596-1601.
    • (1996) J. Virol. , vol.70 , pp. 1596-1601
    • Yamada, O.1    Kraus, G.2    Luznik, L.3    Yu, M.4    Wong-Staal, F.5
  • 90
    • 0026711027 scopus 로고
    • Minimum ribonucleotide requirement for catalysis by the RNA hammerhead domain
    • Yang J.H., Usman N., Chartrand P., Cedergreen R. Minimum ribonucleotide requirement for catalysis by the RNA hammerhead domain. Biochemistry. 31:1992;5005-5009.
    • (1992) Biochemistry , vol.31 , pp. 5005-5009
    • Yang, J.H.1    Usman, N.2    Chartrand, P.3    Cedergreen, R.4
  • 91
    • 0026512220 scopus 로고
    • Hepatitis B virus: New and evolving issues
    • Yoffe B., Noonnan C.A. Hepatitis B virus: new and evolving issues. Digest Dis. Sci. 37:1992;1-9.
    • (1992) Digest Dis. Sci. , vol.37 , pp. 1-9
    • Yoffe, B.1    Noonnan, C.A.2
  • 92
    • 0030967825 scopus 로고    scopus 로고
    • Metal ions play a passive role in the hairpin ribozyme catalyzed reaction
    • Young K.J., Gill F., Grasby J.A. Metal ions play a passive role in the hairpin ribozyme catalyzed reaction. Nucleic Acids Res. 25:1997;3760-3766.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 3760-3766
    • Young, K.J.1    Gill, F.2    Grasby, J.A.3


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