Plasmid-mediated expression of the UmuDC mutagenesis proteins in an Escherichia coli strain engineered for human cytochrome P450 1A2-catalyzed activation of aromatic amines

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 429, Issue 2, 1999, Pages 199-208

  Josephy, P David ^a   Evans, David H ^a   Williamson, Vanessa ^a   Henry, Tracey ^a   Guengerich, F Peter ^b  

^a UNIVERSITY OF GUELPH   (Canada)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cytochrome P450; MucAB; Mutagenesis; UmuDC

Indexed keywords

1 NITROPYRENE; 2 AMINO 3,4 DIMETHYLIMIDAZO[4,5 F]QUINOLINE; 4 NITROQUINOLINE 1 OXIDE; AROMATIC AMINE; BACTERIAL PROTEIN; CYTOCHROME P450 ISOENZYME; PHENACETIN O DEETHYLASE;

ARTICLE; CATALYSIS; CONTROLLED STUDY; ESCHERICHIA COLI; GENE EXPRESSION; GENETIC ENGINEERING; METABOLIC ACTIVATION; MUTAGENESIS; NONHUMAN; OPERON; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMINES; BACTERIAL PROTEINS; CYTOCHROME P-450 CYP1A2; DNA-DIRECTED DNA POLYMERASE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; HUMANS; MUTAGENESIS; MUTAGENICITY TESTS; MUTAGENS; PLASMIDS; PYRENES; QUINOLINES;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0032832691     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(99)00120-7     Document Type: Article

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