Effects of various serotonin agonists, antagonists, and uptake inhibitors on the discriminative stimulus effects of methamphetamine in rats

Journal of Pharmacology and Experimental Therapeutics

Volumn 291, Issue 1, 1999, Pages 239-250

  Munzar, Patrik ^a   Laufert, Michael D ^a   Kutkat, Scott W ^a   Nováková, Jana ^b   Goldberg, Steven R ^a  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^b MASARYK UNIVERSITY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; BUSPIRONE; CLOMIPRAMINE; FLUOXETINE; KETANSERIN; METHAMPHETAMINE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; SEROTONIN UPTAKE INHIBITOR; TROPISETRON;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISCRIMINATIVE STIMULUS; DOSE RESPONSE; DOSE TIME EFFECT RELATION; MALE; NEUROCHEMISTRY; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION; SEROTONIN RELEASE;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANALYSIS OF VARIANCE; ANIMALS; BIGUANIDES; CENTRAL NERVOUS SYSTEM STIMULANTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; INDOLES; MALE; METHAMPHETAMINE; PIPERAZINES; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN; SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; SEROTONIN UPTAKE INHIBITORS;

EID: 0032825337     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (53)

1. Berger UV, Gu XF and Azmitia EC (1992) The substituted amphetamines 3,4-methylenedioxymethamphetamine, methamphetamine, p-chloroamphetamine and fenfluramine induce 5-hydroxytryptamine release via a common mechanism blocked by fluoxetine and cocaine. Eur J Pharmacol 215:153-160.
2. Bobker DH and Williams JT (1991) Cocaine and amphetamine interact at 5-HT synapses through distinct mechanisms in guinea-pig prepositus hypoglossi. J Neurosci 11:2151-2156.
3. Brodie MS and Bunney EB (1996) Serotonin potentiates dopamine inhibition of ventral tegmental area neurons in vitro. J Neurophysiol 76:2077-2082.
4. 2c receptors. J Pharmacol Exp Ther 274:1414-1424.
5. 3 compounds in a drug discrimination model. Pharmacol Biochem Behav 54:533-540.
6. Ehrman RN, Robbins SJ, Cornish JW, Childress AR and O'Brien CP (1996) Failure of ritanserin to block cocaine cue reactivity in humans. Drug Alcohol Dep 42:167-174.
7. Fiorella D, Palumbo PA, Rabin RA and Winter JC (1995) The time-dependent stimulus effects of R(-)-2,5-dimethoxy-4-methamphetamine (DOM): Implications for drug-induced stimulus control as a method for the study of hallucinogenic agents. Psychopharmacology 119:239-245.
8. 1A receptor antagonist. Behav Brain Res 73:337-353.
9. 3 receptors in drug dependence. Drug Alcohol Depend 38:155-171.
10. Guan XM and McBride WJ (1989) Serotonin microinfusion into the ventral tegmental area increases accumbens dopamine release. Brain Res Bull 23:541-547.
11. 2A/2C receptor agonist, potentiates amphetamine-induced dopamine release in rat striatum. Brain Res 698:204-208.
12. Ichikawa J and Meltzer HY (1992) Amperozide, a novel antipsychotic drug, inhibits the ability of d-amphetamine to increase dopamine release in vivo in rat striatum and nucleus accumbens. J Neurochem 58:2285-2291.
13. Iyer RN and Bradberry CW (1996) Serotonin-mediated increase in prefrontal cortex dopamine release: Pharmacological characterization. J Pharmacol Exp Ther 277:40-47.
14. Hoyer D, Clarke DE, Fozard JR, Hartig PR, Martin GR, Mylecharane EJ, Saxena PR and Humphrey PP (1994) International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol Rev 46:157-203.
15. 2 receptor in the methamphetamine-induced neurochemical alterations. J Pharmacol Exp Ther 270:97-103.
16. Kleven MS and Koek W (1998a) Discriminative stimulus effects of 8-hydroxy-2-(di-n-propylamino)-tetralin in pigeons and rats: Species similarities and differences. J Pharmacol Exp Ther 284:238-249.
17. Kleven MS and Koek W (1998b) Discriminative stimulus properties of cocaine: enhancement by monoamine reuptake blockers. J Pharmacol Exp Ther 284:1015-1025.
18. Kleven MS and Koek W (1998c) Pharmacological characterization of the discriminative stimulus effects of cocaine: Enhancement by direct-acting serotonin receptor agonists. Behav Pharmacol 9 (Suppl 1):S50.
19. Koek W, Kleven MS and Colpaert FC (1995) Effects of the NMDA antagonist, dizocilpine, in various drug discriminations: Characterization of intermediate levels of drug lever selection. Behav Pharmacol 6:590-600.
20. Koob GF and Bloom FE (1988) Cellular and molecular mechanisms of drug dependence. Science (Wash DC) 242:715-723.
21. Kuczenski R, Segal DS, Cho AK and Melega W (1995) Hippocampus norepinephrine, caudate dopamine and serotonin, and behavioral responses to the stereoisomers of amphetamine and methamphetamine. J Neurosci 15:1308-1317.
22. 2A/2C receptor agonists potentiate the discriminative cue of (+)-amphetamine in the rat. Neuropharmacology 36:1471-1475.
23. 3 receptor antagonists on the discriminative stimulus effects of amphetamine. Eur J Pharmacol 212:271-274.
24. Munzar P, Baumann MH, Shoaib M and Goldberg SR (1999) Effects of dopamine and serotonin-releasing agents on methamphetamine discrimination and self-administration in rats. Psychopharmacology 141:287-296.
25. Munzar P and Goldberg SR (1999) Noradrenergic modulation of the discriminative-stimulus effects of methamphetamine in rats. Psychopharmacology 143:293-301.
26. Munzar P, Nosal R and Goldberg SR (1998) Potentiation of the discriminative-stimulus effects of methamphetamine by the histamine H3 receptor antagonist thioperamide in rats. Eur J Pharmacol 363:93-101.
27. National Research Council (1996) Guide for the Care and Use of Laboratory Animals. National Academy Press, Washington, DC.
28. Parsons LH and Justice JB (1993) Perfusate serotonin increases extracellular dopamine in the nucleus accumbens as measured by in vivo microdialysis. Brain Res 606:195-199.
29. Peltier RL, Emmett-Oglesby MW, Thomas WH and Schenk S (1994) Failure of ritanserin to block the discriminative or reinforcing stimulus effects of cocaine. Pharmacol Biochem Behav 48:473-478.
30. Phelix CF and Broderick PA (1995) Light microscopic immunocytochemical evidence of converging serotonin and dopamine terminals in ventrolateral nucleus accumbens. Brain Res Bull 37:37-40.
31. Prisco S, Pagannone S and Esposito E (1994) Serotonin-dopamine interactions in the rat ventral tegmental area: An electrophysiological study in vivo. J Pharmacol Exp Ther 271:83-90.
32. 1A receptors attenuates the locomotor, but not the discriminative, effects of amphetamine and cocaine in rats. Behav Pharmacol 8:699-706.
33. Rapoza D (1993) Buspirone fails to affect the discriminative stimulus effects of cocaine. Pharmacol Biochem Behav 45:179-183.
34. Sasaki JE, Tatham TA and Barrett JE (1995) The discriminative stimulus effects of methamphetamine in pigeons. Psychopharmacology 120:303-310.
35. Schama KF, Howell LL and Byrd LD (1997) Serotonergic modulation of the discriminative-stimulus effects of cocaine in squirrel monkeys. Psychopharmacology 132:27-34.
36. Segal DS and Kuczenski R (1997) Repeated binge exposures to amphetamine and methamphetamine: Behavioral and neurochemical characterization. J Pharmacol Exp Ther 282:561-573.
37. 2A/2C antagonist, reverses direct dopamine agonist-induced inhibition of mid-brain dopamine neurons. J Pharmacol Exp Ther 274:735-740.
38. 2 receptor antagonists reverse amphetamine-induced slowing of dopaminergic neurons by interfering with stimulated dopamine synthesis. J Pharmacol Exp Ther 260:872-878.
39. Spealman RD (1993) Modification of behavioral effects of cocaine by selective serotonin and dopamine uptake inhibitors in squirrel monkeys. Psychopharmacology 112:93-99.
40. 2 receptor antagonists: Potential in the treatment of psychiatric disorders. CNS Drugs 7:388-409.
41. Stefanski R, Ladenheim B, Lee SH, Cadet JL and Goldberg SR (1999) Neuroadaptations in the dopaminergic system after active self-administration but not after passive administration of methamphetamine. Eur J Pharmacol 371:123-135.
42. Terry P, Witkin JM and Katz JL (1994) Pharmacological characterization of the novel discriminative stimulus effects of a low dose of cocaine. J Pharmacol Exp Ther 270:1041-1048.
43. Tidey JW and Bergman J (1998) Drug discrimination in methamphetamine-trained monkeys: Agonist and antagonist effects of dopaminergic drugs. J Pharmacol Exp Ther 285:1163-1174.
44. 3 receptor antagonists on 5-HT and nicotinic depolarizations in guinea-pig submucosal neurones. Br J Pharmacol 99:840-844.
45. Walsh SL and Cunningham KA (1997) Serotonergic mechanisms involved in the discriminative stimulus, reinforcing and subjective effects of cocaine. Psychopharmacology 130:41-58.
46. West WB, Van Groll BJ and Appel JB (1995) Stimulus effects of d-amphetamine II: DA, NE, and 5-HT mechanisms. Pharmacol Biochem Behav 51:69-76.
47. Wise RA and Bozarth MA (1987) A psychomotor stimulant theory of addiction. Psychol Rev 94:469-492.
48. Winger GD, Yasar S, Negus SS and Goldberg SR (1994) Intravenous self-administration studies with l-deprenyl (selegiline) in monkeys. Clin Pharmacol Ther 56:774-780.
49. Witkin JM, Savtchenko N, Mashkovsky M, Beekman M, Munzar P, Gasior M, Goldberg SR, Ungard JT, Kim J, Shippenberg T and Chefer V (1999) Behavioral, toxic and neurochemical effects of sydnocarb, a novel psychomotor stimulant: Comparisons with methamphetamine. J Pharmacol Exp Ther 288:1298-1310.
50. Yasar S and Bergman J (1994) Amphetamine-like effect of l-deprenyl in drug-discrimination studies. Clin Pharmacol Ther 56:768-773.
51. Yasar S, Schindler CW, Thorndike EB and Goldberg SR (1994) Evaluation of deprenyl for cocaine-like discriminative stimulus effects in rats. Eur J Pharmacol 259:243-250.
52. Yasar S, Schindler CW, Thorndike EB, Szelenyi I and Goldberg SR (1993) Evaluation of the stereoisomers of deprenyl for amphetamine-like discriminative stimulus effects in rats. J Pharmacol Exp Ther 265:1-6.
53. Yokel RA and Pickens R (1973) Self-administration of optical isomers of amphetamine and methylamphetamine by rats. J Pharmacol Exp Ther 187:27-33.