Detailed investigations of 5-HT3 compounds in a drug discrimination model

Pharmacology Biochemistry and Behavior

Volumn 54, Issue 3, 1996, Pages 533-540

  De La Garza II, Richard ^a   Callahan, Patrick M ^a   Cunningham, Kathryn A ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

5 HT3 receptors; Cocaine; Drug discrimination; mCPBG; MDL 72222; Ondansetron; Zacopride

Indexed keywords

1 (3 CHLOROPHENYL)BIGUANIDE; BEMESETRON; COCAINE; ONDANSETRON; SEROTONIN 3 AGONIST; SEROTONIN 3 ANTAGONIST; SEROTONIN 3 RECEPTOR; ZACOPRIDE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISCRIMINATIVE STIMULUS; DRUG ANTAGONISM; DRUG DISCRIMINATION; DRUG EFFECT; DRUG SCREENING; LOCOMOTION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 0029942974     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/0091-3057(95)02207-4     Document Type: Article

References (30)

1. 3 receptors in the rat striatum. J. Pharmacol. Exp. Ther. 251:803-809; 1989.
2. Bradberry, C. W.; Roth, R. H. Cocaine increases extracellular dopamine in rat nucleus accumbens and ventral tegmental area as shown by in vivo microdialysis. Neurosci. Lett. 103:97-102; 1989.
3. 2 mediation of the discriminative stimulus properties of d-amphetamine and cocaine. Psychopharmacology (Berlin) 103: 50-55; 1991.
4. 3 receptor antagonists block morphine- and nicotine- but not amphetamine-induced reward. Psychopharmacology (Berlin) 97:175-178; 1989.
5. 3 receptors by 1-phenylbiguanide increases dopamine release in the rat nucleus accumbens. Brain Res. 543:354-357; 1991.
6. Costall, B.; Jones, B. J.; Kelly, M. E.; Naylor, R. J.; Onaivi, E. S.; Tyers, M. B. Sites of action of ondansetron to inhibit withdrawal from drugs of abuse. Pharmacol. Biochem. Behav. 36:97-104; 1990.
7. 3 receptor antagonist, GR38032F, on raised dopaminergic activity in the mesolimbic system of the rat and marmoset brain. Br. J. Pharmacol. 92:881-894; 1987.
8. 3 antagonists of hyperactivity caused by dopamine infusion into rat nucleus accumbens. Br. J. Pharmacol. 93:194P; 1987.
9. 3 antagonist zacopride on the development and expression of cocaine-induced sensitization. Soc. Neurosci. Abstr. 19:1850; 1993.
10. Extance, K.; Goudie, A. J. Inter-animal olfactory cues in operant drug discrimination procedures in rats. Psychopharmacology (Berlin) 73:363-371; 1981.
11. Fozard, J. R.; Mobarok, A. T. M.; Newgrosh, G. Blockade of serotonin receptors on autonomic neurones by (-) cocaine and some related compounds. Eur. J. Pharmacol. 59:195-210; 1979.
12. 3 antagonists. Psychopharmacology (Berlin) 104:451-456; 1991.
13. 3 receptor antagonists MDL 72222 and ondansetron an morphine place conditioning. Psychopharmacology (Berlin) 106:315-320; 1992.
14. 3 receptor antagonist 2-methylserotonin on the release of dopamine in the nucleus accumbens: An in vivo chronocoulometric study. Brain Res. 513:156-160; 1990.
15. Kennett, G. A.; Blackburn, T. P. Inhibition of agonist-induced dopamine release in the nucleus accumbens by BRL 46470, an in vivo dialysis study. Soc. Neurosci. Abstr. 17:239.7; 1991.
16. 3 receptors in the rat central nervous system are mainly located on nerve fibers and terminals. Brain Res. 612:289-298; 1993.
17. 3 receptors in rat brain using radioligand binding. Nature 330:746-748; 1987.
18. Koe, B. K. Molecular geometry of inhibitors of the uptake of catecholamines and serotonin in synaptosomal preparations of rat brain. J. Pharmacol. Exp. Ther. 199:649-661; 1976.
19. Lane, J. D.; Pickering, C. L.; Hooper, M. L.; Fagan, K.; Tyers, M. B.; Emmett-Oglesby, M. W. Failure of ondansetron to block the discriminative stimulus effects of cocaine in the rat. Drug Alcohol Depend. 30:151-162; 1992.
20. 3 antagonist zacopride attenuates cocaine-induced increases in extracellular dopamine in rat nucleus accumbens. Pharmacol. Biochem. Behav. 45:759-763; 1993.
21. Moghaddam, B.; Bunney, B. S. Differential effects of cocaine on extracellular dopamine in rat medial prefrontal cortex and nucleus accumbens: Comparison to amphetamine. Synapse 4:156-161; 1989.
22. Oakley, N. R.; Jones, B. J.; Tyers, M. B.; Costall, B.; Domeney, A. M. The effect of GR38032F on alcohol consumption in the marmoset. Br. J. Pharmacol. 95:870P; 1988.
23. 3 antagonists do not alter the discriminative stimulus properties of cocaine. Psychopharmacology (Berlin) 104:475-478; 1991.
24. 3 antagonist fails to alter cocaine self-administration in rats. Pharmacol. Biochem. Behav. 39:133-136; 1991.
25. 3 receptor antagonists attenuate cocaine-induced locomotion in mice. Eur. J. Pharmacol. 186:327-330; 1990.
26. 3 antagonist, partially attenuates the effects of amphetamine: A pilot study in healthy volunteers. Int. Clin. Psychopharmacol. 7:37-43; 1992.
27. Sullivan, J. T.; Jasinski, D. R.; Preston, K. L.; Testai, M. P.; Bell, J. M. Cocaine blocking effects of ondansetron. NIDA Monogr. 119:170-176; 1992.
28. 3 receptor antagonists block cocaine-induced locomotion via a PCPA-sensitive mechanism. Pharmacol. Biochem. Behav. 43:871-879; 1992.
29. 3 antagonist, reduces cocaine's psychomotor stimulated effects in the rat. Psychopharmacology (Berlin) 101:S59; 1990.
30. Young, R.; Glennon, R. A. Zacopride and its optical isomers produce stereoselective antagonism of a 2-methylserotonin discriminative stimulus. Eur. J. Pharmacol. 212:117-119; 1992.