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Volumn 20, Issue 8, 1999, Pages 1417-1424

Inefficient in vivo repair of mismatches at an oncogenic hotspot correlated with lack of binding by mismatch repair proteins and with phase of the cell cycle

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA BINDING PROTEIN; MONOCLONAL ANTIBODY; POLYDEOXYRIBONUCLEOTIDE SYNTHASE;

EID: 0032818869     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/20.8.1417     Document Type: Article
Times cited : (12)

References (52)
  • 2
    • 0029938649 scopus 로고    scopus 로고
    • The role of adduct site-specific mutagenesis in understanding how carcinogen-DNA adducts cause mutations: Perspective, prospects and problems
    • Loechler, E.L. (1996) The role of adduct site-specific mutagenesis in understanding how carcinogen-DNA adducts cause mutations: perspective, prospects and problems. Carcinogenesis, 17, 895-902.
    • (1996) Carcinogenesis , vol.17 , pp. 895-902
    • Loechler, E.L.1
  • 4
    • 0023898932 scopus 로고
    • The ras gene family and human carcinogenesis
    • Bos, J.L. (1988) The ras gene family and human carcinogenesis. Mutat. Res., 195, 255-271.
    • (1988) Mutat. Res. , vol.195 , pp. 255-271
    • Bos, J.L.1
  • 5
    • 0029022018 scopus 로고
    • Mutations of ras genes in human tumors
    • Kiaris, H. and Spandidos, D.A. (1995) Mutations of ras genes in human tumors. Int. J. Oncol., 7, 413-421.
    • (1995) Int. J. Oncol. , vol.7 , pp. 413-421
    • Kiaris, H.1    Spandidos, D.A.2
  • 6
    • 0024236909 scopus 로고
    • Oncogene activation in chemical carcinogenesis
    • Balmain, A. and Brown, K. (1988) Oncogene activation in chemical carcinogenesis. Adv. Cancer Res., 51, 147-182.
    • (1988) Adv. Cancer Res. , vol.51 , pp. 147-182
    • Balmain, A.1    Brown, K.2
  • 7
    • 0029806936 scopus 로고    scopus 로고
    • Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in p53
    • Denissenko, M.F., Pao, A., Tang, M.-S. and Pfeifer, G.P. (1996) Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in p53. Science, 274, 430-432.
    • (1996) Science , vol.274 , pp. 430-432
    • Denissenko, M.F.1    Pao, A.2    Tang, M.-S.3    Pfeifer, G.P.4
  • 8
    • 0032523812 scopus 로고    scopus 로고
    • Carcinogens preferentially bind at methylated CpG in the p53 mutational hot spots
    • Chen, J.X., Zheng, Y., West, M. and Tang, M.-S. (1998) Carcinogens preferentially bind at methylated CpG in the p53 mutational hot spots. Cancer Res., 58, 2070-2075.
    • (1998) Cancer Res. , vol.58 , pp. 2070-2075
    • Chen, J.X.1    Zheng, Y.2    West, M.3    Tang, M.-S.4
  • 9
    • 0028215974 scopus 로고
    • Slow repair of pyrimidine dimers at p53 mutation hotspots in skin cancer
    • Tornaletti, S. and Pfeifer, G.P. (1994) Slow repair of pyrimidine dimers at p53 mutation hotspots in skin cancer. Science, 263, 1436-1440.
    • (1994) Science , vol.263 , pp. 1436-1440
    • Tornaletti, S.1    Pfeifer, G.P.2
  • 10
    • 0032510267 scopus 로고    scopus 로고
    • Slow repair of bulky DNA adducts along the nontranscribed strand of the human p53 gene may explain the strand bias of transversion mutations in cancers
    • Denissenko, M.F., Pao, A., Pfeifer, G.P. and Tang, M.-S. (1998) Slow repair of bulky DNA adducts along the nontranscribed strand of the human p53 gene may explain the strand bias of transversion mutations in cancers. Oncogene, 16, 1241-1247.
    • (1998) Oncogene , vol.16 , pp. 1241-1247
    • Denissenko, M.F.1    Pao, A.2    Pfeifer, G.P.3    Tang, M.-S.4
  • 11
    • 0028848633 scopus 로고
    • Mutagenicity of a unique 8-oxoguanine in a human H-ras sequence in mammalian cells
    • Le Page, K., Margot, A., Grollman, A.P., Sarasin, A. and Gentil, A. (1995) Mutagenicity of a unique 8-oxoguanine in a human H-ras sequence in mammalian cells. Carcinogenesis, 16, 2779-2784.
    • (1995) Carcinogenesis , vol.16 , pp. 2779-2784
    • Le Page, K.1    Margot, A.2    Grollman, A.P.3    Sarasin, A.4    Gentil, A.5
  • 12
    • 0028272140 scopus 로고
    • Mutagenesis in monkey cells of a vector containing a single d(GpG) cis-diamminedichloroplatinum(II) adduct placed on codon 13 of the human H-ras proto-oncogene
    • Pillaire, M., Margot, A., Villani, G., Sarasin, A., Defais, M. and Gentil, A. (1994) Mutagenesis in monkey cells of a vector containing a single d(GpG) cis-diamminedichloroplatinum(II) adduct placed on codon 13 of the human H-ras proto-oncogene. Nucleic Acids Res., 22, 2519-2524.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 2519-2524
    • Pillaire, M.1    Margot, A.2    Villani, G.3    Sarasin, A.4    Defais, M.5    Gentil, A.6
  • 13
    • 0029665108 scopus 로고    scopus 로고
    • 6-benzylguanine incorporated site-specifically in codon 12 of the rat H-ras gene induced semi-targeted as well as targeted mutations in Rat4 cells
    • 6-benzylguanine incorporated site-specifically in codon 12 of the rat H-ras gene induced semi-targeted as well as targeted mutations in Rat4 cells. Carcinogenesis, 17, 849-856.
    • (1996) Carcinogenesis , vol.17 , pp. 849-856
    • Bishop, R.E.1    Pauly, G.T.2    Moschel, R.C.3
  • 14
    • 0031060263 scopus 로고    scopus 로고
    • Chromosome instability syndromes: Lessons for carcinogenesis
    • Meyn, M.S. (1997) Chromosome instability syndromes: lessons for carcinogenesis. Curr. Top. Microbiol. Immunol., 221, 72-148.
    • (1997) Curr. Top. Microbiol. Immunol. , vol.221 , pp. 72-148
    • Meyn, M.S.1
  • 15
    • 0029943449 scopus 로고    scopus 로고
    • Mismatch repair in replication fidelity, genetic recombination and cancer biology
    • Modrich, P. and Lahue, R. (1996) Mismatch repair in replication fidelity, genetic recombination and cancer biology. Annu. Rev. Biochem., 65, 101-133.
    • (1996) Annu. Rev. Biochem. , vol.65 , pp. 101-133
    • Modrich, P.1    Lahue, R.2
  • 17
    • 0027742295 scopus 로고
    • The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
    • Fishel, R., Lescoe, M.K., Rao, M.R., Copeland, N.G., Jenkins, N.A., Garber, J., Kane, M. and Kolodner, R. (1993) The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell, 75, 1027-1038.
    • (1993) Cell , vol.75 , pp. 1027-1038
    • Fishel, R.1    Lescoe, M.K.2    Rao, M.R.3    Copeland, N.G.4    Jenkins, N.A.5    Garber, J.6    Kane, M.7    Kolodner, R.8
  • 19
    • 0029784320 scopus 로고    scopus 로고
    • Biochemistry and genetics of eukaryotic mismatch repair
    • Kolodner, R. (1996) Biochemistry and genetics of eukaryotic mismatch repair. Genes Dev., 10, 1433-1442.
    • (1996) Genes Dev. , vol.10 , pp. 1433-1442
    • Kolodner, R.1
  • 20
    • 0030861915 scopus 로고    scopus 로고
    • DNA glycosylases in the base excision repair of DNA
    • Krokan, H.E., Standal, R. and Slupphaug, G. (1997) DNA glycosylases in the base excision repair of DNA. Biochem. J., 325, 1-16.
    • (1997) Biochem. J. , vol.325 , pp. 1-16
    • Krokan, H.E.1    Standal, R.2    Slupphaug, G.3
  • 21
    • 0027095976 scopus 로고
    • The purification of a human mismatch-binding protein and identification of its associated ATPase and helicase activities
    • Hughes, M.J. and Jiricny, J. (1992) The purification of a human mismatch-binding protein and identification of its associated ATPase and helicase activities. J. Biol. Chem., 267, 23876-23882.
    • (1992) J. Biol. Chem. , vol.267 , pp. 23876-23882
    • Hughes, M.J.1    Jiricny, J.2
  • 22
    • 0029070143 scopus 로고
    • Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells
    • Drummond, J.T., Li, G.-M., Longley, M.J. and Modrich, P. (1995) Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells. Science, 268, 1909-1912.
    • (1995) Science , vol.268 , pp. 1909-1912
    • Drummond, J.T.1    Li, G.-M.2    Longley, M.J.3    Modrich, P.4
  • 24
    • 0025314841 scopus 로고
    • Mismatch-specific thymine DNA glycosylase and DNA polymerase β mediate the correction of G-T mispairs in nuclear extracts from human cells
    • Wiebauer, K. and Jiricny, J. (1990) Mismatch-specific thymine DNA glycosylase and DNA polymerase β mediate the correction of G-T mispairs in nuclear extracts from human cells. Proc. Natl Acad. Sci. USA, 87, 5842-5845.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 5842-5845
    • Wiebauer, K.1    Jiricny, J.2
  • 25
    • 0028831129 scopus 로고
    • Characterization of a mammalian homolog of the Escherichia coli Mut Y mismatch repair protein
    • McGoldrick, J.P., Yeh, Y.-C., Solomon, M., Essigmann, J.M. and Lu, A.-L. (1995) Characterization of a mammalian homolog of the Escherichia coli Mut Y mismatch repair protein. Mol. Cell. Biol., 15, 989-996.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 989-996
    • McGoldrick, J.P.1    Yeh, Y.-C.2    Solomon, M.3    Essigmann, J.M.4    Lu, A.-L.5
  • 26
    • 0029616260 scopus 로고
    • DNA repair fine structure and its relations to genomic instability
    • Bohr, V.A. (1995) DNA repair fine structure and its relations to genomic instability. Carcinogenesis, 16, 2885-2892.
    • (1995) Carcinogenesis , vol.16 , pp. 2885-2892
    • Bohr, V.A.1
  • 28
    • 0031911779 scopus 로고    scopus 로고
    • DNA mismatch repair catalyzed by extracts of mitotic, postmitotic and senescent Drosophila tissues and involvement of mei-9 gene function for full activity
    • Bhui-Kaur, A., Goodman, M.F. and Tower, J. (1998) DNA mismatch repair catalyzed by extracts of mitotic, postmitotic and senescent Drosophila tissues and involvement of mei-9 gene function for full activity. Mol. Cell. Biol., 18, 1436-1443.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 1436-1443
    • Bhui-Kaur, A.1    Goodman, M.F.2    Tower, J.3
  • 29
    • 0029838771 scopus 로고    scopus 로고
    • Expression of human MutS homolog 2 (hMSH2) protein in resting and proliferating cells
    • Marra, G., Chang, C.L., Laghi, L.A., Chauhan, D.P., Young, D. and Boland, C.R. (1996) Expression of human MutS homolog 2 (hMSH2) protein in resting and proliferating cells. Oncogene, 13, 2189-2196.
    • (1996) Oncogene , vol.13 , pp. 2189-2196
    • Marra, G.1    Chang, C.L.2    Laghi, L.A.3    Chauhan, D.P.4    Young, D.5    Boland, C.R.6
  • 31
    • 0031883948 scopus 로고    scopus 로고
    • Expression of long-patch and short-patch DNA mismatch repair proteins in the embryonic and adult mammalian brain
    • Marietta, C., Palombo, R., Gallinari, P., Jiricny, J. and Brooks, P.J. (1998) Expression of long-patch and short-patch DNA mismatch repair proteins in the embryonic and adult mammalian brain. Mol. Brain Res., 53, 317-320.
    • (1998) Mol. Brain Res. , vol.53 , pp. 317-320
    • Marietta, C.1    Palombo, R.2    Gallinari, P.3    Jiricny, J.4    Brooks, P.J.5
  • 33
    • 0031419008 scopus 로고    scopus 로고
    • Site-and strand-specific mismatch repair of human H-ras genomic DNA in a mammalian cell line
    • Arcangeli, L., Simonetti, J., Pongrantz, C. and Williams, K.J. (1997) Site-and strand-specific mismatch repair of human H-ras genomic DNA in a mammalian cell line. Carcinogenesis, 18, 1311-1318.
    • (1997) Carcinogenesis , vol.18 , pp. 1311-1318
    • Arcangeli, L.1    Simonetti, J.2    Pongrantz, C.3    Williams, K.J.4
  • 34
    • 0029018789 scopus 로고
    • Mammalian assay for site-specific DNA damage processing using the human H-ras proto-oncogene
    • Arcangeli, L. and Williams, K.J. (1995) Mammalian assay for site-specific DNA damage processing using the human H-ras proto-oncogene. Nucleic Acids Res., 23, 2269-2276.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 2269-2276
    • Arcangeli, L.1    Williams, K.J.2
  • 35
    • 0021988550 scopus 로고
    • Stable replication of plasmids derived from Epstein-Barr virus in various mammalian cells
    • Yates, J., Warren, N. and Sugden, B. (1985) Stable replication of plasmids derived from Epstein-Barr virus in various mammalian cells. Nature, 313, 812-815.
    • (1985) Nature , vol.313 , pp. 812-815
    • Yates, J.1    Warren, N.2    Sugden, B.3
  • 36
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignum, J.D. (1983) Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res., 11, 1475-1489.
    • (1983) Nucleic Acids Res. , vol.11 , pp. 1475-1489
    • Dignum, J.D.1
  • 37
    • 0030962031 scopus 로고    scopus 로고
    • Genetic and biochemical analysis of Msh2p-Msh6p: Role of ATP hydrolysis and Msh2p-Msh6p subunit interactions in mismatch base pair recognition
    • Alani, E., Sokolsky, T., Studamire, B., Miret, J.J. and Lahue, R.S. (1997) Genetic and biochemical analysis of Msh2p-Msh6p: role of ATP hydrolysis and Msh2p-Msh6p subunit interactions in mismatch base pair recognition. Mol. Cell. Biol., 17, 2436-2447.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 2436-2447
    • Alani, E.1    Sokolsky, T.2    Studamire, B.3    Miret, J.J.4    Lahue, R.S.5
  • 38
    • 0031456973 scopus 로고    scopus 로고
    • The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switch
    • Gradia, S., Acharya, S. and Fishel, R. (1997) The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switch. Cell, 91, 995-1005.
    • (1997) Cell , vol.91 , pp. 995-1005
    • Gradia, S.1    Acharya, S.2    Fishel, R.3
  • 39
    • 0032079736 scopus 로고    scopus 로고
    • HMSH2 and hMSH6 play distinct roles in mismatch binding and contribute differently to the ATPase activity of hMutSα
    • Iaccarino, I., Marra, G., Palombo, F. and Jiricny J. (1998) hMSH2 and hMSH6 play distinct roles in mismatch binding and contribute differently to the ATPase activity of hMutSα. EMBO J., 17, 2677-2686.
    • (1998) EMBO J. , vol.17 , pp. 2677-2686
    • Iaccarino, I.1    Marra, G.2    Palombo, F.3    Jiricny, J.4
  • 40
  • 41
    • 0027215870 scopus 로고
    • Codons 12 and 13 of H-ras protooncogene interrupt the progression of DNA synthesis catalyzed by DNA polymerase a
    • Huffman, J.-S., Fry, M., Ji, J., Williams, K.J. and Loeb, L.A. (1993) Codons 12 and 13 of H-ras protooncogene interrupt the progression of DNA synthesis catalyzed by DNA polymerase a. Cancer Res., 53, 2895-2900.
    • (1993) Cancer Res. , vol.53 , pp. 2895-2900
    • Huffman, J.-S.1    Fry, M.2    Ji, J.3    Williams, K.J.4    Loeb, L.A.5
  • 42
    • 0025340001 scopus 로고
    • Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines
    • Holmes, J. Jr, Clark, S. and Modrich, P. (1990) Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines. Proc. Natl Acad. Sci. USA, 87, 5837-5841.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 5837-5841
    • Holmes J., Jr.1    Clark, S.2    Modrich, P.3
  • 43
    • 0023803187 scopus 로고
    • Different base/base mispairs are corrected with different efficiencies and specificities in monkey kidney cells
    • Brown, T.C. and Jiricny, J. (1988) Different base/base mispairs are corrected with different efficiencies and specificities in monkey kidney cells. Cell, 54, 705-711.
    • (1988) Cell , vol.54 , pp. 705-711
    • Brown, T.C.1    Jiricny, J.2
  • 44
    • 0025777777 scopus 로고
    • Heteroduplex repair in extracts of human Hela cells
    • Thomas, D.C., Roberts, J.D. and Kunkel, T.A. (1991) Heteroduplex repair in extracts of human HeLa cells. J. Biol. Chem., 266, 3744-3751.
    • (1991) J. Biol. Chem. , vol.266 , pp. 3744-3751
    • Thomas, D.C.1    Roberts, J.D.2    Kunkel, T.A.3
  • 45
    • 0025129834 scopus 로고
    • DNA mismatch repair in Xenopus egg extracts: Repair efficiency and DNA repair synthesis for all single base-pair mismatches
    • Varlet, I., Radman, M. and Brooks, P. (1990) DNA mismatch repair in Xenopus egg extracts: repair efficiency and DNA repair synthesis for all single base-pair mismatches. Proc. Natl Acad. Sci. USA, 87, 7883-7887.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 7883-7887
    • Varlet, I.1    Radman, M.2    Brooks, P.3
  • 46
    • 0030815268 scopus 로고    scopus 로고
    • DNA replication and postreplication mismatch repair in cell-free extracts from cultured human neuroblastoma and fibroblast cells
    • David, P., Efrati, E., Tocco, G., Krauss, S.W. and Goodman, M.F. (1997) DNA replication and postreplication mismatch repair in cell-free extracts from cultured human neuroblastoma and fibroblast cells. J. Neurosci., 17, 8711-8720.
    • (1997) J. Neurosci. , vol.17 , pp. 8711-8720
    • David, P.1    Efrati, E.2    Tocco, G.3    Krauss, S.W.4    Goodman, M.F.5
  • 47
    • 0030800632 scopus 로고    scopus 로고
    • Mismatch repair by efficient nick-directed and less efficient mismatch-specific, mechanisms in homologous recombination intermediates in Chinese hamster ovary cells
    • Miller, E.M., Hough, H.L., Cho, J.W. and Nickoloff, J.A. (1997) Mismatch repair by efficient nick-directed and less efficient mismatch-specific, mechanisms in homologous recombination intermediates in Chinese hamster ovary cells. Genetics, 147, 743-753.
    • (1997) Genetics , vol.147 , pp. 743-753
    • Miller, E.M.1    Hough, H.L.2    Cho, J.W.3    Nickoloff, J.A.4
  • 48
    • 0032584384 scopus 로고    scopus 로고
    • Isolation of MutSβ from human cells and comparison of the mismatch repair specificities of MutSβ and MutSα
    • Genschel, J., Littman, S.J., Drummond, J.T. and Modrich, P. (1998) Isolation of MutSβ from human cells and comparison of the mismatch repair specificities of MutSβ and MutSα. J. Biol. Chem., 273, 19895-19901.
    • (1998) J. Biol. Chem. , vol.273 , pp. 19895-19901
    • Genschel, J.1    Littman, S.J.2    Drummond, J.T.3    Modrich, P.4
  • 49
    • 0028176720 scopus 로고
    • Mammalian topoisomerase I has base mismatch nicking activity
    • Yeh, Y.-C., Liu, H.-F., Ellis, C.A. and Lu, A.-L. (1994) Mammalian topoisomerase I has base mismatch nicking activity. J. Biol. Chem., 269, 15498-15504.
    • (1994) J. Biol. Chem. , vol.269 , pp. 15498-15504
    • Yeh, Y.-C.1    Liu, H.-F.2    Ellis, C.A.3    Lu, A.-L.4
  • 50
    • 0028286268 scopus 로고
    • Purification and characterization of a novel deoxyinosine-specific enzyme, deoxyinosine 3′ endonuclease, from Escherichia coli
    • Yao, M., Hatahet, Z., Melamede, R.J. and Kow, Y.W. (1994) Purification and characterization of a novel deoxyinosine-specific enzyme, deoxyinosine 3′ endonuclease, from Escherichia coli. J. Biol. Chem., 269, 16260-16268.
    • (1994) J. Biol. Chem. , vol.269 , pp. 16260-16268
    • Yao, M.1    Hatahet, Z.2    Melamede, R.J.3    Kow, Y.W.4
  • 51
    • 0032126812 scopus 로고    scopus 로고
    • Frameshift mismatch recognition by the human MutSα complex
    • Macpherson, P., Humbert, O. and Karran, P. (1998) Frameshift mismatch recognition by the human MutSα complex. Mutat. Res., 408, 55-66.
    • (1998) Mutat. Res. , vol.408 , pp. 55-66
    • Macpherson, P.1    Humbert, O.2    Karran, P.3
  • 52
    • 0032029577 scopus 로고    scopus 로고
    • Repair and mutagenic potency of 8-oxoG:A and 8-oxoG:C base pairs in mammalian cells
    • Le Page, F., Guy, A., Cadet, J., Sarasin, A. and Gentil, A. (1998) Repair and mutagenic potency of 8-oxoG:A and 8-oxoG:C base pairs in mammalian cells. Nucleic Acids Res., 26, 1276-1281.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 1276-1281
    • Le Page, F.1    Guy, A.2    Cadet, J.3    Sarasin, A.4    Gentil, A.5


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