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Volumn 880, Issue , 1999, Pages 31-37

Tumor suppressor gene Smad4/DPC4, its downstream target genes, and regulation of cell cycle

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P21; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

EID: 0032788607     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1999.tb09507.x     Document Type: Conference Paper
Times cited : (30)

References (26)
  • 2
    • 0000619592 scopus 로고    scopus 로고
    • Molecular biology and the diagnosis and treatment of adenocarcinoma of the pancreas
    • 2. DIGIUSEPPE, J.A., C.J. YEO & R.H. HRUBAN. 1996. Molecular biology and the diagnosis and treatment of adenocarcinoma of the pancreas. Adv. Anal. Pathol. 3: 139-155.
    • (1996) Adv. Anal. Pathol. , vol.3 , pp. 139-155
    • DiGiuseppe, J.A.1    Yeo, C.J.2    Hruban, R.H.3
  • 3
    • 0030070277 scopus 로고    scopus 로고
    • Preoperative chemoradiation, pancreaticoduodenectomy, and intraoperative radiation therapy for adenocarcinoma of the pancreatic head: Patient survival and patterns of treatment failure
    • 3. STALEY, C.A., J.E. LEE, K.A. CLEARY, J.L. ABBRUZZESE, F.C. AMES, C. FENOGLIO & D.B. EVANS. 1996. Preoperative chemoradiation, pancreaticoduodenectomy, and intraoperative radiation therapy for adenocarcinoma of the pancreatic head: Patient survival and patterns of treatment failure. Am. J. Surg. 171: 118-124.
    • (1996) Am. J. Surg. , vol.171 , pp. 118-124
    • Staley, C.A.1    Lee, J.E.2    Cleary, K.A.3    Abbruzzese, J.L.4    Ames, F.C.5    Fenoglio, C.6    Evans, D.B.7
  • 5
    • 0030604542 scopus 로고    scopus 로고
    • TGF-b signaling: Receptors, transducers, and mad proteins
    • 5. MASSAGUE, J. 1996. TGF-b signaling: Receptors, transducers, and mad proteins. Cell 85: 947-950.
    • (1996) Cell , vol.85 , pp. 947-950
    • Massague, J.1
  • 6
    • 0027421280 scopus 로고
    • Resistance to inhibition of cell growth by transforming growth factor-b and its role in oncogenesis
    • 6. FYNAN, T.M. & M. REISS. 1993. Resistance to inhibition of cell growth by transforming growth factor-b and its role in oncogenesis. Crit. Rev. Oncog. 4: 493-540.
    • (1993) Crit. Rev. Oncog. , vol.4 , pp. 493-540
    • Fynan, T.M.1    Reiss, M.2
  • 7
    • 0030612484 scopus 로고    scopus 로고
    • Induction of p21 waf1 expression and growth inhibition by transforming growth factor-b involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells
    • 7. GRAU, A.M., L. ZHANG, W. WANG, S. RUAN, D.B. EVANS, A.L. ABBRUZZESE, W. ZHANG & P.J. CHIAO. 1997. Induction of p21 waf1 expression and growth inhibition by transforming growth factor-b involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells. Cancer Res. 57: 3929-3934.
    • (1997) Cancer Res. , vol.57 , pp. 3929-3934
    • Grau, A.M.1    Zhang, L.2    Wang, W.3    Ruan, S.4    Evans, D.B.5    Abbruzzese, A.L.6    Zhang, W.7    Chiao, P.J.8
  • 8
  • 9
    • 0031911356 scopus 로고    scopus 로고
    • SMADs: Mediators and regulators of TGF-b signaling
    • 9. KRETZSCHMAR, M. & J. MASSAGUE. 1998. SMADs: Mediators and regulators of TGF-b signaling. Curr. Opin. Genet. Dev. 8: 103-111.
    • (1998) Curr. Opin. Genet. Dev. , vol.8 , pp. 103-111
    • Kretzschmar, M.1    Massague, J.2
  • 10
    • 0031128153 scopus 로고    scopus 로고
    • The tumor suppressor Smad4/DPC4 as a central mediator of Smad function
    • 10. ZHANG, Y., T. MUSCI & R. DERYNCK. 1997. The tumor suppressor Smad4/DPC4 as a central mediator of Smad function. Curr. Biol. 7: 270-276.
    • (1997) Curr. Biol. , vol.7 , pp. 270-276
    • Zhang, Y.1    Musci, T.2    Derynck, R.3
  • 11
    • 0030872367 scopus 로고    scopus 로고
    • Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic
    • 11. KIM, J., K. JOHNSON, H. J. CHEN, S. CARROLL & A. LAUGHON. 1997. Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic. Nature 388: 304-308.
    • (1997) Nature , vol.388 , pp. 304-308
    • Kim, J.1    Johnson, K.2    Chen, H.J.3    Carroll, S.4    Laughon, A.5
  • 12
    • 0029802485 scopus 로고    scopus 로고
    • A transcriptional partner for MAD proteins in TGF-b signaling
    • 12. CHEN, X., M.J. ROBOCK & M. WHITMAN. 1996. A transcriptional partner for MAD proteins in TGF-b signaling. Nature 383: 691-696.
    • (1996) Nature , vol.383 , pp. 691-696
    • Chen, X.1    Robock, M.J.2    Whitman, M.3
  • 16
    • 0029786212 scopus 로고    scopus 로고
    • Receptor-associated Mad homologues synergize as effectors of the TGF-beta response
    • 16. ZHANG, Y., X. FENG, R. WE & R. DERYNCK. 1996. Receptor-associated Mad homologues synergize as effectors of the TGF-beta response. Nature 383: 168-172.
    • (1996) Nature , vol.383 , pp. 168-172
    • Zhang, Y.1    Feng, X.2    We, R.3    Derynck, R.4
  • 17
    • 0029833909 scopus 로고    scopus 로고
    • Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth
    • 17. YINGLING, J.M., P. DAS, C. SAVAGE, M. ZHANG, R.W. PADGETT & X.F. WANG. 1996. Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth. Proc. Natl. Acad. Sci. USA 93: 8940-8944.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 8940-8944
    • Yingling, J.M.1    Das, P.2    Savage, C.3    Zhang, M.4    Padgett, R.W.5    Wang, X.F.6
  • 18
    • 0029834067 scopus 로고    scopus 로고
    • Partnership between DPC4 and SMAD proteins in TGF-b signalling pathways
    • 18. LAGNA, G., A. HATA, A. HEMMATI-BRIVANLOU & J. MASSAGUE. 1996. Partnership between DPC4 and SMAD proteins in TGF-b signalling pathways Nature 383: 832-836.
    • (1996) Nature , vol.383 , pp. 832-836
    • Lagna, G.1    Hata, A.2    Hemmati-Brivanlou, A.3    Massague, J.4
  • 19
    • 0028793568 scopus 로고
    • Increased tumorigenicity in the human pancreatic cell line MTA PaCa-2 is associated with an aberrant regulation of an IGF-1 autocrine loop and lack of expression of the TGF-b type RII receptor
    • 19. FREEMAN, J.W., C.A. MATTINGLY & W.E. STRODEL. 1995. Increased tumorigenicity in the human pancreatic cell line MTA PaCa-2 is associated with an aberrant regulation of an IGF-1 autocrine loop and lack of expression of the TGF-b type RII receptor. J. Cell Physiol. 165: 155-163.
    • (1995) J. Cell Physiol. , vol.165 , pp. 155-163
    • Freeman, J.W.1    Mattingly, C.A.2    Strodel, W.E.3
  • 22
    • 0028970946 scopus 로고
    • p53-independent expression of the cyclin-dependent kinase inhibitor p21 in pancreatic carcinoma
    • 22. DIGIUSEPPE, J.A., M.S. REDSTON, C.J. YEO, S.E. KERN & R.H. HRUBAN. 1995. p53-independent expression of the cyclin-dependent kinase inhibitor p21 in pancreatic carcinoma. Am. J. Pathol. 147: 884-888.
    • (1995) Am. J. Pathol. , vol.147 , pp. 884-888
    • DiGiuseppe, J.A.1    Redston, M.S.2    Yeo, C.J.3    Kern, S.E.4    Hruban, R.H.5
  • 24
    • 0032499789 scopus 로고    scopus 로고
    • Regulation of the human p21/WAF1/Cip1 Promoter in hepatic cells by functional interactions between Sp1 and Smad family members
    • 24. MOUSTAKAS, A. & D. KARDASSIS. 1998. Regulation of the human p21/WAF1/Cip1 Promoter in hepatic cells by functional interactions between Sp1 and Smad family members. Proc. Natl. Acad. Sci. USA 95: 6733-6738.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 6733-6738
    • Moustakas, A.1    Kardassis, D.2
  • 25
    • 0030690337 scopus 로고    scopus 로고
    • Dual role of the Smad4/DPC4 tumor suppressor in TGFb-inducible transcriptional complexes
    • 25. Liu, F., C. POUPONNOT & J. MASSAGUE. 1997. Dual role of the Smad4/DPC4 tumor suppressor in TGFb-inducible transcriptional complexes. Genes & Dev. 11: 5157-3167.
    • (1997) Genes & Dev. , vol.11 , pp. 5157-13167
    • Liu, F.1    Pouponnot, C.2    Massague, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.