Isolation, physical mapping, and Northern analysis of the X-linked human gene encoding methyl CpG-binding protein, MECP2

Mammalian Genome

Volumn 7, Issue 7, 1996, Pages 533-535

  D'Esposito, M ^a   Quaderi, N A ^c   Ciccodicola, A ^a,b   Bruni, P ^a   Esposito, T ^a,b   D'Urso, M ^a   Brown, S D M ^c  

^a INSTITUTE OF GENETICS AND BIOPHYSICS ADRIANO BUZZATI TRAVERSO   (Italy)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTIDYLYL 3' 5' GUANOSINE; CYTIDYLYL-3'-5'-GUANOSINE; DINUCLEOSIDE PHOSPHATE; DNA; DNA BINDING PROTEIN; MECP2 PROTEIN, HUMAN; MECP2 PROTEIN, MOUSE; MECP2 PROTEIN, RAT; METHYL CPG BINDING PROTEIN 2; NONHISTONE PROTEIN; PRIMER DNA; REPRESSOR PROTEIN;

ADULT; AMINO ACID SEQUENCE; ANIMAL; ANTIBODY SPECIFICITY; ARTICLE; CHROMOSOME MAP; COSMID; GENETICS; HAMSTER; HUMAN; HYBRID CELL; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; MOUSE; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; RAT; SEQUENCE HOMOLOGY; X CHROMOSOME; YEAST ARTIFICIAL CHROMOSOME;

ADULT; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BLOTTING, NORTHERN; CHROMOSOMAL PROTEINS, NON-HISTONE; CHROMOSOME MAPPING; CHROMOSOMES, ARTIFICIAL, YEAST; CLONING, MOLECULAR; CONSERVED SEQUENCE; COSMIDS; CRICETINAE; DINUCLEOSIDE PHOSPHATES; DNA; DNA PRIMERS; DNA-BINDING PROTEINS; HUMANS; HYBRID CELLS; METHYL-CPG-BINDING PROTEIN 2; MICE; MOLECULAR SEQUENCE DATA; ORGAN SPECIFICITY; RATS; REPRESSOR PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; X CHROMOSOME;

EID: 0030188404     PISSN: 09388990     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003359900157     Document Type: Article

References (19)

1. Adler, D.A., Quaderi, N.A., Brown, S.D.M., Chapman, V.M., Moore, J., Tate, P., Disteche, C. (1995). The X-linked methylated DNA binding protein, Mecp2, is subject to X inactivation in mouse. Mamm. Genome, 6, 491-492.
2. Blanchard, M.M., Taillon-Miller, P., Novotny, P., Novotny, W. (1993). PCR buffer optimization with uniform temperature regimen to facilitate automation. PCR Methods Appl. 2, 234-240.
3. Brown, C.J., Flenniken, A.M., Williams, B.R.G., Willard, H.F. (1990. X chromosome inactivation of the human TIMP gene. Nucleic Acids Res. 18, 4191-4195.
4. Brown, C.J., Ballabio, A., Rupert, J.L., Lafreniere, R.G., Grompe, M., Tonlorenzi, R., Willard, H.F. (1991). A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome. Nature 349, 38-44.
5. Brown, S.D.M., Avner, P., Boyd, Y., Chapman, V., Rastan, S., Sefton, L., Thomas, J.D., Herman, G.E. (1993). Mouse X chromosome. Mamm. Genome 4(Suppl.), S269-S281.
6. Davies, K.E., Mandel, J.L., Monaco, A.P., Nussbaum, R.L., Willard, H.F. (1992). Report of the committee on the genetic constitution of the X chromosome. Cytogenet. Cell Genet. 58, 1-117.
7. Dietrich, A., Korn, B., Poutska, A. (1992). Completion of the physical map of Xq28: the location of the gene for LICAM on the human X chromosome. Mamm. Genome 3, 168-172.
8. Kaneko, K., Warren, S.T., Miyatake, T., Tsuji, S. (1993) Isolation of 353 Not I linking clones and 62 DNA markers (DXS607-DXS668) from human chromosome Xq24-qter. Cytogenet. Cell Genet. 64, 5-8.
9. Levinson, B., Kenwrick, S., Lakich, D., Hammonds, G., Gitschier, J. (1990). A transcribed gene in an intron of the human factor VIII gene. Genomics 7, 1-11.
10. Levinson, B., Bermingham, J.R., Metzenberg, A., Kenwrick, S., Chapman, V., Gitschier, J. (1992). Sequence of the factor VIII-associated gene is conserved in mouse. Genomics 13, 862-865.
11. Lewis, J.D., Meehan, R.R., Henzel, W.J., Maurer-Fogy, I., Jeppesen, P., Klein, F., Bird, A.P. (1992). Purification, sequence and cellular localisation of a novel chromosomal protein that binds to methylated DNA. Cell 69, 905-914.
12. Li, E., Bestor, T.H., Jaenisch, R. (1992). Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69, 915-926.
13. Meehan, R.R., Lewis, J.D., McKay, S., Kleiner, E.L., Bird, A.P. (1989). Identification of a mammalian protein that binds specifically to DNA that contains methylated CpGs. Cell 58, 499-507.
14. Meehan, R.R., Lewis, J.D., Bird, A.P. (1992a). Characterisation of MeCP2, a vertebrate DNA binding protein with affinity for methylated DNA. Nucleic Acids Res. 20, 5085-5092.
15. Meehan, R.R., Lewis, J.D., Cross, S.H., Nan, X., Jeppesen, P., Bird, A.P. (1992b). Transcriptional repression by methylation of CpG. J. Cell Sci. 16, 9-14.
16. Nan, X., Meehan, R.R., Bird, A.P. (1993). Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2. Nucleic Acids Res. 21, 4886-4892.
17. Palmieri, G., Romano, G., Ciccodicola, A., Casamassimi, A., Campanile, C., Esposito, T., Cappa, V., Lania, A., Johnson, S., Reinbold, R., Poutska, A., Schlessinger, D., D'Urso, M. (1994). YAC contig organisation and CpG island analysis in Xq28. Genomics 24, 149-158.
18. Quaderi, N.A., Meehan, R.R., Tate, P.H., Cross, S.H., Bird, A.P., Chatterjee, A., Herman, G.E., Brown, S.D.M. (1994). Genetic and physical mapping of a gene encoding a methyl CpG binding protein, Mecp2, to the mouse X chromosome. Genomics 22, 648-651.
19. Tate, P., Skarnes, W., Bird, A. (1996). The methyl-CpG binding protein MeCP2 is essential for embryonic development in the mouse. Nature Genet. 12, 205-208.