Inactivation block of the HERG human cardiac K+ channels by RP58866

British Journal of Pharmacology

Volumn 127, Issue 8, 1999, Pages 1899-1907

  Wang, Huizhen ^a   Shi, Hong ^a   Wang, Zhiguo ^a,b  

^a MONTREAL HEART INSTITUTE   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Channel inactivation; HERG; RP58866; Two electrode voltage clamp; Xenopus oocyte

Indexed keywords

MUTANT PROTEIN; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; TERIKALANT;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG PROTEIN BINDING; HEART ELECTROPHYSIOLOGY; HEART VENTRICLE FIBRILLATION; MEMBRANE DEPOLARIZATION; NONHUMAN; OOCYTE; POTASSIUM CURRENT; PRIORITY JOURNAL; VOLTAGE CLAMP; XENOPUS;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; CHROMANS; DOSE-RESPONSE RELATIONSHIP, DRUG; HEART; HUMANS; MEMBRANE POTENTIALS; MYOCARDIUM; PATCH-CLAMP TECHNIQUES; PIPERIDINES; POTASSIUM CHANNELS; XENOPUS;

EID: 0032775104     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702741     Document Type: Article

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