Inhibition of the expression and function of chemokine receptors on human CD4+ leukocytes by HIV-1 envelope protein gp 120

Chemical Immunology

Volumn 72, Issue , 1999, Pages 141-160

  Su, Shao Bo ^a   Ueda, Hirotsugu ^a   Howard, O M Zack ^a,b   Grimm, Michael C ^a   Gong, Wanghua ^a,b   Ruscetti, Francis W ^a   Oppenheim, Joost J ^a   Wang, Ji Ming ^a,b  

^a SAIC FREDERICK INC   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CHEMOATTRACTANT; CHEMOKINE RECEPTOR; GLYCOPROTEIN GP 120; VIRUS ENVELOPE PROTEIN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; CULTURE MEDIUM; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LEUKOCYTE; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; REVIEW; T LYMPHOCYTE;

EID: 0032773244     PISSN: 10150145     EISSN: None     Source Type: Journal    
DOI: 10.1159/000058731     Document Type: Review

References (31)

1. Klatzmann D, Champagne E, Chamaret S, Gruest J, Guetars D, Hercend T, Gluckman JC, Montaggnier L: T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV. Nature 1984;312:767-768.
2. Dalgleish AG, Beverley PC, Clapham PR, Crawford DH, Greaves MF, Weiss RA: The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus. Nature 1984;312:763-767.
3. Premack BA, Schall TJ: Chemokine receptors: Gateways to inflammation and infection. Nat Med 1996;2:1174-1178.
4. Bleul CC, Farzan M, Choc H, Parolin C, Clark-Lewis I, Sodroski J, Springer TA: The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry. Nature 1996;382:829-832.
5. Oberlin E, Amara A, Bachelerie F, Bessia C, Virelizier JL, Arenzana-Seisdedos F, Schwartz O, Heard JM, Clark-Lewis I, Legler DF, Loetscher M, Baggilini M, Moser B: The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1. Nature 1996;382:833-835.
6. Feng Y, Broder CC, Kennedy PE, Berger EA: HIV-1 entry cofactor: Functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science 1996;272:872-877.
7. Deng HK, Liu R, Ellmeier W, Choe H, Unutmaz D, Burkhart M, Di Marzio P, Marmon S, Sutton RE, Hill CM, Davis C, Peiper SC, Schall TJ, Littman DR, Landau NR: Identification of major co-receptor for primary isolates of HIV-1. Nature 1996;381:661-666.
8. Dragic T, Litwin V, Allaway GP, Martin SR, Huang Y, Nagashima KA, Paxton WA: HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5. Nature 1996;381:667-673.
9. Alkhatib G, Combatiere C, Broder CC, Feng Y, Kennedy PE, Murphy PM, Berger EA: CC CKR5: A RANTES, MIP-1α, MLIP-1β receptor as a fusion cofactor for macrophage-tropic HIV-1. Science 1996;272:1955-1958.
10. Liu R, Paxton WA, Choc H, Ceradini D, Martin SR, Horuk R, MacDonald ME, Stuhlmann H, Koup RA, Landau NR: Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell 1996;86:367-377.
11. Choe H, Farzan M, Sun Y, Sullivan N, Rollins B, Ponath PD, Wu L, Mackay CR, LaRosa G, Newman W, Gerard N, Gerard C, Sodroski J: The β-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell 1996;85:1135-1148.
12. Doranz BJ, Rucker J, Yi Y, Smyth RJ, Samson M, Peiper SC, Parmentier M, Collman RG, Doms RW: A dual-tropic primary HIV-1 isolate that uses fusin and the β-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors. Cell 1996;85:1149-1158.
13. Liao F, Alkhatib G, Peden KW, Sharma G, Berger EA, Farber JM: STRL33, a novel chemokine receptor-like protein, functions as a fusion cofactor for both macrophage-tropic and T cell line-tropic HIV-1. J Exp Med 1997;185:2015-2023.
14. Trkola A, Dragic T, Arthos J, Binley JM, Olson WC, Allaway GP, Cheng-Mayer C, Robinson J, Maddon PJ, Moore JP: CD4-dependent, antibody-sensitive interactions between HIV-1 and its coreceptor CCR-5. Nature 1996;384:184-187.
15. Wu L, Gerard NP, Wyatt R, Choe H, Parolin C, Ruffing N, Borsetti A, Cardoso AA, Desjardin E, Newman W, Gerard C, Sodroski J: CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5. Nature 1996;384:179-183.
16. Ugoni S, Moulard IM, Mondor I, Barois N, Demandolx D, Hoxie J, Brelot A, Alizon M, Davoust J, Sattentau QJ: HIV-1 gp120 induces an association between CD4 and the chemokine receptor CXCR4. J Immunol 1997;159:3000-3008.
17. Kornfeld H, Cruikshank WW, Pyle SW, Berman JS, Center DM: Lymphocyte activation by HIV-1 envelope glycoprotein. Nature 1988;335:445-448.
18. Weissman D Rabin RL, Arthos J, Rubbert A, Dybul M, Swofford R, Venkatesan S, Farber JM, Fauci A: Macrophage-tropic HIV and SIV envelope proteins induce a signal through the CCR5 chemokine receptor. Nature 1997;389:982-985.
19. Smith PD, Ohura K, Masur H, Lane HC, Fauci AS, Wahl SM: Monocyte function in the acquired immune deficiency syndrome. Defective chemotaxis. J Clin Invest 1984;74:2121-2128.
20. Wahl SM, Allen JB, Gartner S, Orenstein JM, Popovic M, Chenoweth DE, Arthur LO, Farrar WL, Wahl LM: HIV-1 and its envelope glycoprotein down-regulate chemotactic ligand receptors and chemotactic function of peripheral blood monocytes. J Immunol 1989;142:3553-3559.
21. Gelderblom HR, Hausmann EHS, Ozel M, Pauli G, Koch MA: Fine structure of human immunodeficiency virus (HIV) and immunolocalization of structural proteins. Virology 1987;156:171-176.
22. Cruikshank WW, Center DM, Pyle SW, Kornfeld H: Biologic activities of HIV-1 envelope glycoprotein: The effects of crosslinking. Biomed Pharmacother 1990;44:5-11.
23. Pyle SW, Dubois GC, Robey WG, Bess JW Jr, Fischinger PJ, Arthur LO: Purification and characterization of the external envelope glycoprotein from two human immunodeficiency virus type 1 variants, HTLV-IIIB and HTLV-IIIRF. J Virol 1988;62:2258-2264.
24. Xu LL, McVicar DW, Ben-Baruch A, Kuhns DB, Johnston J, Oppenheim JJ, Wang JM: Monocyte chemotactic protein-3 (MCP3) interacts with multiple leukocyte receptors: Binding and signaling of MCP3 through shared as well as unique receptors on monocytes and neutrophils. Eur J Immunol 1995;25:2616-2617.
25. Murphy PM: Chemokine receptors: Structure, function and role in microbial pathogenesis. Cytokine Growth Factor Rev 1996;7:47-64.
26. Combadiere C, Ahuja SK, Tiffany HL, Murphy PM: cloning and functional expression of CC CKR5, a human monocyte CC chemokine receptor selective for MIP-1α, MIP-1β and RANTES. J Leukoc Biol 1996;60:147-152.
27. Neote K, DiGregorio D, Ma JY, Horuk R, Schall TJ: Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor. Cell 1993;72:415-425.
28. Gao JL, Kuhns DB, Tiffany HL, McDermot D, Li X, Francke U, Murphy PM: Structure and functional expression of the human macrophage inflammatory protein 1α/RANTES receptor. J Exp Med 1993;177:1421-1427.
29. Gong X, Gong W, Kuhns DB, Ben-Baruch A, Howard OMZ, Wang JM: Monocyte chemotactic protein-2 (MCP-2) uses CCR1 and CCR2B as its functional receptors. J Biol Chem 1997;272:11682-11685.
30. Cocchi F, DeVico AL, Garzino-Demo A, Arya SK, Gallo RC, Lusso P: Identification of RANTES, MIP-1α, MIP-1β as the major HIV-suppressive factors produced by CD8+ T cells. Science 1995;270:1811-1815.
31. Cocchi F, DeVico AL, Garzino-Demo A, Gallo RC, Lusso P: The V3 domain of the HIV-1 gp120 envelope glycoprotein is critical for chemokine-mediated blockade of infection. Nat Med 1996;2:1244-1247.