Carotenoids and gene regulation

Nutrition Reviews

Volumn 57, Issue 6, 1999, Pages 182-191

  Bertram, John S ^a  

^a UNIVERSITY OF HAWAII CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAROTENOID; CONNEXIN 43; RETINOID;

ARTICLE; CANCER PREVENTION; CANCER RISK; CARCINOGENESIS; CELL COMMUNICATION; FOOD INTAKE; FRUIT; GAP JUNCTION; GENE CONTROL; MALIGNANT TRANSFORMATION; PROTEIN EXPRESSION; SMOKING; VEGETABLE;

ANIMALIA;

EID: 0032769850     PISSN: 00296643     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1753-4887.1999.tb06941.x     Document Type: Article

References (46)

1. Doll R, Peto R. The causes of cancer. Oxford: Oxford University Press, 1981
2. Mayne ST. Beta-carotene, carotenoids, and disease prevention in humans. FASEB J 1996;10:690-701
3. Moon RC, Mehta RG, Rao KVN. Retinoids and cancer in experimental animals. In: Sporn MB, Roberts AB, Goodman DS, eds. The retinoids, 2nd ed. New York: Raven Press, 1994;573-96
4. Hong WK, Itri LM. Retinoids and human cancer. In: Sporn MB, Roberts AB, Goodman DS, eds. The retinoids, 2nd ed. New York: Raven Press, 1994;597-630
5. Giovannucci E, Ascherio A, Rimm EB, et al. Intake of carotenoids and retinol in relation to risk of prostate cancer. J Natl Cancer Inst 1995;87:1767-76
6. Kanetsky PA, Gammon MD, Mandelblatt J, et al. Dietary intake and blood levels of lycopene: association with cervical dysplasia among non-Hispanic, black women. Nutr Cancer 1998;31:31-40
7. Bertram JS, Kolonel LN, Meyskens FL. Rationale and strategies for chemoprevention of cancer in humans. Cancer Res 1987;47:3012-31
8. White WS, Peck KM, Ulman EA, Erdman Jr JW. The ferret as a model for evaluation of the bioavailabilities of all-trans-ß-carotene and its isomers. J Nutr 1993;123:1129-39
9. Poor CL, Bierer TL, Merchen NR, et al. Evaluation of the preruminant calf as a model for the study of human carotenoid metabolism. J Nutr 1992;122: 262-8
10. Matthews-Roth MM, Krinsky NI. Carotenoids affect development of UB-B induced skin cancer. Photochem Photobiol 1987;46:507-9
11. Tanaka T, Morishita Y, Suzui M, et al. Chemoprevention of mouse urinary bladder carcinogenesis by the naturally occurring carotenoid astaxanthin. Carcinogenesis 1994;15:15-9
12. Reznikoff CA, Bertram JS, Brankow DW, Heidelberger C. Quantitative and qualitative studies of chemical transformation of cloned C3H mouse embryo cells sensitive to postconfluence inhibition of cell division. Cancer Res 1973;33:2339-49
13. Merriman R, Bertram JS. Reversible inhibition by retinoids of 3-methylcholanthrene-induced neoplastic transformation in C3H10T1/2 cells. Cancer Res 1979;39:1661-6
14. Papadimitrakopoulou VA, Hong WK, Lee JS, et al. Low-dose isotretinoin versus ß-carotene to prevent oral carcinogenesis: long-term follow-up. J Natl Cancer Inst 1997;89:257-8
15. Pung A, Rundhaug JE, Yoshizawa CN, Bertram JS. ß-Carotene and canthaxanthin inhibit chemically- and physically-induced neoplastic transformation in 10T1/2 cells. Carcinogenesis 1988;9:1533-9
16. Bertram JS, Pung A, Churley M, et al. Diverse carotenoids protect against chemically induced neoplastic transformation. Carcinogenesis 1991;12:671-8
17. Som S, Chatterjee M, Banarjee M. ß-Carotene inhibition of 7,12-dimethylbenz[a]anthracene-induced transformation of murine cells. Carcinogenesis 1984;5:937-40
18. Ames BN, Shigenaga MK, Gold LS. DNA lesions, inducible DNA repair, and cell division: three key factors in mutagenesis and carcinogenesis. Environ Health Perspect 1993;101(5[suppl]):35-44
19. Zhang L-X, Cooney RV, Bertram JS. Carotenoids enhance gap junctional communication and inhibit lipid peroxidation in C3H/10T1/2 cells: relationship to their cancer chemopreventive action. Carcinogenesis 1991;12:2109-14
20. Banoub RW, Fernstrom M, Ruch RJ. Lack of growth inhibition or enhancement of gap junctional intercellular communication and connexin43 expression by ß-carotene in murine lung epithelial cells in vitro. Cancer Lett 1996;108:35-40
21. Stahl W, Nicolai S, Briviba K, et al. Biological activities of natural and synthetic carotenoids: induction of gap junctional communication and singlet oxygen quenching. Carcinogenesis 1997;18:89-92
22. Mehta PP, Bertram JS, Loewenstein WR. Growth inhibition of transformed cells correlates with their junctional communication with normal cells. Cell 1986;44:187-96
23. Mordan LJ, Bertram JS. Retinoid effects on cell-cell interactions and growth characteristics of normal and carcinogen-treated C3H/10T1/2 cells. Cancer Res 1983;43:567-71
24. Milks LC, Kumar NM, Houghten R, et al. Topology of the 32-kd liver gap junction protein determined by site-directed antibody localizations. EMBO J 1988;7:2967-75
25. Beyer EC, Paul DL, Goodenough DA. Connexin family of gap junction proteins. J Membr Biol 1990;116:187-94
26. Nicholson SM, Bruzzone R. Gap junctions: getting the message through. Curr Biol 1997;7:R340-4
27. Neveu M, Bertram JS. Gap junctions and neoplasia. In: Hertzberg EL, ed. Gap junctions: advances in cellular and molecular biology. Greenwich: JAI Press, 1999, in press
28. Loewenstein WR. Junctional intercellular communication and the control of growth. Biochim Biophys Acta 1979;560:1-65
29. Enomoto T, Yamasaki H. Lack of intercellular communication between chemically transformed and surrounding nontransformed BALB/c 3T3 cells. Cancer Res 1984;44:5200-3
30. Sakr W, Tabaska P, Kucuk O, Bertram JS. Differential expression of connexin 43 in normal, preneoplastic and neoplastic squamous epithelium of the upper aerodigestive tract (abstract). Proceedings of the American Association for Cancer Research 1996;37:269
31. Kinzler KW, Vogelstein B. Lessons from hereditary colorectal cancer. Cell 1996;87:159-70
32. Mehta PP, Bertram JS, Loewenstein WR. The actions of retinoids on cellular growth correlate with their actions on gap junctional communication. J Cell Biol 1989;108:1053-65
33. Chambon P. A decade of molecular biology of retinoic acid receptors. FASEB J 1996;10:940-54
34. DiSepio D, Jones A, Longley MA, et al. The proximal promoter of the mouse loricrin gene contains a functional AP-1 element and directs keratinocyte-specific but not differentiation-specific expression. J Biol Chem 1995;18:10792-9
35. Lefebvre DL, Piersanti M, Bai XH, et al. Myometrial transcriptional regulation of the gap junction gene, connexin-43. Reprod Fertil Dev 1995;7:603-11
36. Geimonen E, Jiang W, Ali M, et al. Activation of protein kinase C in human uterine smooth muscle induces connexin-43 gene transcription through an AP-1 site in the promoter sequence. J Biol Chem 1996;271:23667-74
37. Newton DL, Henderson WR, Sporn MB. Structure-activity relationships of retinoids in hamster tracheal organ culture. Cancer Res 1980;40:3413-25
38. Rundhaug J, Gubler ML, Sherman MI, et al. Differential uptake, binding and metabolism of retinol and retinoic acid in 10T1/2 cells. Cancer Res 1987;47:5637-43
39. Zhang L, Cooney RV, Bertram JS. Carotenoids up-regulate connexin43 gene expression independent of their pro-vitamin A or antioxidant properties. Cancer Res 1992;52:5707-12
40. Acevedo P, Bertram JS. Liarozole potentiates the cancer chemopreventive activity of and the up-regulation of gap junctional communication and connexin43 expression by retinoic acid and ß-carotene in 10T1/2 cells. Carcinogenesis 1995;16:2215-22
41. Hanusch M, Stahl W, Schulz WA, Sies H. Induction of gap junctional communication by 4-oxoretinoic acid generated from its precursor canthaxanthin. Arch Biochem Biophys 1995;317:423-8
42. Stahl W, Hanusch M, Sies H. 4-oxo-retinoic acid is generated from its precursor canthaxanthin and enhances gap junctional communication in 10T1/ 2 cells. Adv Exp Med Biol 1996;387:121-8
43. Renaud JP, Rochel N, Ruff M, et al. Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid. Nature 1995;378:681-9
44. Holmbeck SM, Foster MP, Casimiro DR, et al. High-resolution solution structure of the retinoid X receptor DNA-binding domain. J Mol Biol 1998;281:271-84
45. Khachik F, Beecher GR, Smith JC. Lutein, lycopene and their oxidative metabolites in chemoprevention of cancer. J Cell Biochem 1995;22:236-46
46. King TJ, Khachik F, Bortkiewicz H, et al. Metabolites of dietary carotenoids as potential cancer preventive agents. Pure and Applied Chemistry 1997;69:2135-40