Polymorphism and domain variability of human killer cell inhibitory receptors

Immunological Reviews

Volumn 155, Issue , 1997, Pages 183-196

  Selvakumar, Annamalai ^a   Steffens, Uwe ^a   Dupont, Bo ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; HLA ANTIGEN CLASS 1; IMMUNOGLOBULIN; LYMPHOCYTE RECEPTOR; LYSINE; MESSENGER RNA; PROTEIN TYROSINE PHOSPHATASE;

ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; DNA POLYMORPHISM; GENE DELETION; HUMAN; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; REVIEW; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; HUMANS; KILLER CELLS, NATURAL; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, IMMUNOLOGIC;

EID: 0031038782     PISSN: 01052896     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-065X.1997.tb00951.x     Document Type: Review

References (57)

1. Karlhofer FM, Ribaudo RK, Yokoyama WM. MHC class I alloantigen specificity of LY49+ IL-2-activated natural killer cells. Nature 1992;358:66-70.
2. Yokoyama WM, Seaman WE. The Ly-49 and NKR-P1 gene families encoding lectin-like receptors on natural killer cells: the NK gene complex. Am Rev Immunol 1993;11:613-635.
3. Yokoyama WM, Kehn PJ, Cohen DI, Shevach EM. Chromosomal location of the Ly-49 (A1. YE1/48) multigene family: genetic association with the NK1.1 antigen. J Immunol 1990;145:2353-2358.
4. Smith HRC, Karlhofer FM, Yokoyama WM. LY-49 multigene family expressed by IL-2-activated NK cells. J Immunol 1994;153:1068-1079.
5. Correa I, Corral L, Raulet DH. Multiple natural killer cell-activating signals are inhibited by major histocompatibility complex class I expression in target cells. Eur J Immunol 1994;24:1323-1331.
6. Long EO, Colonna M, Lanier LL. Inhibitory MHC class I receptors on NK and T cells: a standard nomenclature. Immunology Today 1996;17:100.
7. Moretta A, et al. A novel surface antigen expressed by a subset of human CD3- CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function. J Exp Med 1990;171:695-714.
8. Moretta A, et al. Identification of four subsets of human CD3-CD16+ natural killer (NK) cells by the expression of clonally distributed functional surface molecules: correlation between subset assignment of NK clones and ability to mediate specific alloantigen recognition. J Exp Med 1990;172:1589-1598.
9. Moretta A, et al. P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities. J Exp Med 1993;178:597-604.
10. Litwin V, Gumperz J, Parham P, Phillips JH, Lanier LL. NKB1: a natural killer cell receptor involved in the recognition of polymorphic HLA-B molecules. J Exp Med 1994;180:537-543.
11. Colonna M, et al. Alloantigen recognition by human natural killer cells is associated with HLA-C or a closely linked gene. Proc Natl Acad Sci USA 1992;89:7983-7985.
12. Colonna M, Borsellino G, Falco M, Ferrara GB, Strominger JL. HLA-C is the inhibitory ligand that determines dominant resistance to lysis by NK1 - and NK2-specific NK cells. Proc Natl Acad Sci USA 1993;90:12000-12004.
13. Biassoni R, et al. Amino acid substitutions can influence the NK-mediated recognition of HLA-C molecules. Role of serine-77 and lysine-80 in the target cell protection from lysis mediated by "group 2" or "group 1" NK clones. J Exp Med 1995;182:605-609.
14. Lanier LL. The role of natural killer cells in transplantation. Cur Opin Immunol 1995;7:626-631.
15. Gumperz JE, Parham P. The enigma of the natural killer cell. Nature 1995;378:245-248.
16. Colonna M. Natural killer cell receptors specific for MHC class I molecules. Curr Opin Immunol 1996;8:101-107.
17. Moretta A, et al. Receptors for HLA class I molecules in human natural killer cells. Ann Rev Immunol 1996;14:619-648.
18. Mandelboim O, et al. Protection from lysis by natural killer cells of group 1 and 2 specificity is mediated by residue 80 in human histocompatibility leukocyte antigen C alleles and also occurs with empty major histocompatibility complex molecules. J Exp Med 1996;184:913-922.
19. Cella M, Longo A, Ferrara GB, Strominger JL, Colonna M. NK3-specific natural killer cells are selectively inhibited by Bw4-positive HLA alleles with isoleucine 80. J Exp Med 1994;180:1235-1242.
20. Gumperz JE, Litwin V, Phillips JH, Lanier LL, Parham P. The Bw4 public epitope of HLA-B molecules confers reactivity with natural killer cell clones that express NKB1, a putative HLA receptor. J Exp Med 1995;181:1133-1144.
21. Döhring C, Scheidegger D, Samaridis J, Cella M, Colonna M. A human killer inhibitory receptor specific for HLA- A. J Immunol 1996;156:3098-3101.
22. Colonna M, Samaridis J. Cloning of immunoglobulin- superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells. Science 1995;268:405-408.
23. Wagtmann N, et al. Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains. Immunity 1995;2:439-449.
24. D'Andrea A, Chang C, Franz-Bacon K, McClanahan T, Phillips JH, Lanier LL. Molecular cloning of NKB1, a natural killer cell receptor for HLA-B allotypes. J Immunol 1995;155:2306-2310.
25. Wagtmann N, Rajagopalan S, Winter CC, Peruzzi M, Long EO. Killer cell inhibitory receptors specific for HLA-C and HLA-B identified by direct binding and by functional transfer. Immunity 1995;3:801-809.
26. Döhring C, Colonna M. Human natural killer cell inhibitory receptors bind to HLA class I molecules. Eur J Immunol 1996;26:365-369.
27. D'Ambrosio D, et al. Recruitment and activation of PTP1C in negative regulation of antigen receptor signaling by FcγRIIB. Science 1995;268:293-297.
28. Doody GM, et al. A role in B cell activati on for CD22 and the protein tyrosine phosphatase SHP. Science 1995;269:242-244.
29. Burshtyn DN, et al. Recruitment of tyrosine phosphatase HCP by the killer cell inhibitory receptor. Immunity 1996;4:77-85.
30. Fry AM, Lanier LL, Weiss A. Phosphotyrosines in the killer cell inhibitory receptor motif of NKB1 are required for negative signaling and for association with protein tyrosine phosphatase 1C. J Exp Med 1996;184:295-300.
31. Campbell KS, Dessing M, López-Botet M, Cella M, Colonna M. Tyrosine phosphorylation of a human killer inhibitory receptor recruits protein tyrosine phosphatase 1C. J Exp Med 1996;184:93-110.
32. Olcese L, et al. Human and mouse killer-cell inhibitory receptors recruit PTP1C and PTP1D protein tyrosine phosphatases. J Immunol 1996;156:4531-4534.
33. Ono M, Bolland S, Tempst P, Ravetch JV. Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor FcγRIIB. Nature 1996;383:263-266.
34. Moretta A, et al. Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells. J Exp Med 1995;182:875-884.
35. Biassoni R, et al. The human leukocyte antigen (HLA)-C-specific "activatory" or "inhibitory" natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions. J Exp Med 1996;183:645-650.
36. D'Andrea A, Chang C, Phillips JH, Lanier LL. Regulation of T cell lymphokine production by killer cell inhibitory receptor recognition of self HLA class I alleles. J Exp Med 1996;184:789-794.
37. Hood L, Kronenberg M, Hunkapiller T. T cell antigen receptors and the immunoglobin supergene family. Cell 1985;40:225-229.
38. Williams AF, Barclay AN. The immunoglobulin superfamily-domains for cell surface recognition. Ann Rev Immunol 1988;6:381-405.
39. Selvakumar A, Steffens U, Dupont B. NK cell receptor gene of the KIR family with two Ig domains but highest homology to KIR receptors with three Ig domains. Tissue Antigens 1996;48:285-295.
40. Parham P, Lawlor DA, Salter RD, Lomen CE, Bjorkman PJ, Ennis PD. HLA-A,B,C: Patterns of polymorphism in peptide-binding proteins. In: Dupont B, ed. Immunobiology of HLA. Vol II. New York: Springer-Verlag, 1989:10-33.
41. Wu TT, Kabat E. An analysis of the sequences of the variable regions of Bence Jones proteins and myeloma light chains and their implications for antibody complementarity. J Exp Med 1970;132:211-250.
42. Cunningham BA, Hemperly JJ, Murray BA, Prediger EA, Backenbury R, Edelman GM. Neural cell adhesion molecule: structure, immunoglobulin-like domains, cell surface modulation, and alternative RNA splicing. Science 1987;236:799-804.
43. Cyculsky MI, et al. Gene structure, chromosomal location, and basis for alternative mRNA splicing of the human VCAM-1 gene. Proc Natl Acad Sci USA 1991;88:7859-7863.
44. Inobe M, Linsley PS, Ledbetter JA, Nagai Y, Tamakoshi M, Uede T. Identification of an alternatively spliced form of the murine homologue of B7. Biochem Biophys Res Commun 1994;200:443-449.
45. Borriello F, Freeman GJ, Edelhoff S, Disteche CM, Nadler LM, Sharpe AH. Characterization of the murine B7-1 genomic locus reveals an additional exon encoding an alternative cytoplasmic domain and a chromosomal location of chromosome 16, Band B5. J Immunol 1994;153:5038-5048.
46. King PD, Sandberg ET, Selvakumar A, Fang P, Beaudet AL, Dupont B. Novel isoforms of murine intercellular adhesion molecule-1 generated by alternative RNA splicing. J Immunol 1995;154:6080-6093.
47. Cudkowicz G. Natural resistance to foreign hemopoetic and leukemia grafts. In: Cudkowicz G, Landy M, Shearer GM, eds. Natural resistance systems against foreign cells, tumors and microbes. New York: Academic Press, 1978:1-3.
48. Yu YY, Kumar V, Bennett M. Murine natural killer cells and marrow graft rejection. Ann Rev Immunol 1992;10:189-213.
49. Yokoyama WM. Hybrid resistance and the Ly49 family of natural killer cell receptors. J Exp Med 1995;182:273-277.
50. Bix M, Liao N-S, Zijlstra M, Loring J, Jaenisch R, Raulet D. Rejection of class I MHC-deficient haemopoietic cells by irradiated MHC-matched mice. Nature 1991;349:329-331.
51. Ljunggren H-G, Van Kaer L, Ploegh HL, Tonegawa S. Altered natural killer cell repertoire in Tap-1 mutant mice. Proc Natl Acad Sci USA 1994;91:6520-6524.
52. Höglund P, et al. Recognition of β2-microglobulin-negative (β2m-) T-cell blasts by natural killer cells from normal but not from β2m-mice: nonresponsiveness controlled by β2m-bone marrow in chimeric mice. Proc Natl Acad Sci USA 1991;88:10332-10336.
53. Held W, Roland J, Raulet DH. Allelic exclusion of Ly49-family genes encoding class I MHC-specific receptors on NK cells. Nature 1995;376:355-358.
54. Moretta A, et al. Human natural killer cell receptors for HLA-class I molecules: evidence that the Kp43 (CD94) molecule functions as receptor for HLA-B alleles. J Exp Med 1994;180:540-555.
55. Chang C, Rodriguez A, Carretero M, López-Botet M, Phillips JH, Lanier LL. Molecular characterization of human CD94: a type II membrane glycoprotein related to the C-type lectin superfamily. Eur J Immunol 1995;25:2433-2437.
56. Phillips JH, Chang C, Mattson J, Gumperz JE, Parham P, Lanier LL. CD94 and a novel associated protein (94AP) form a NK cell receptor involved in the recognition of HLA-A, HLA-B, and HLA-C allotypes. Immunity 1996;5:163-172.
57. Pende D, et al. The natural killer cell receptor specific for HLA-A allotypes: A novel member of the p58/p70 family of inhibitory receptors that is characterized by three Ig-like domains and is expressed as a 140 kD disulphide-linked dimer. J Exp Med 1996;184:505-551.