In vitro digestion/Caco-2 cell culture model to determine optimal ascorbic acid to Fe ratio in rice cereal

Journal of Food Science

Volumn 64, Issue 5, 1999, Pages 925-928

  Glahn, R P ^a   Lee, O A ^b   Miller, D D ^b  

^a AGRICULTURAL RESEARCH SERVICE   (United States)

^b Cornell Univ ^*  (United States)

Author keywords

Ascorbic acid; Caco 2; Cereal; Iron; Rice

Indexed keywords

MALUS X DOMESTICA;

EID: 0032743822     PISSN: 00221147     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2621.1999.tb15942.x     Document Type: Article

References (13)

1. Brune, M., Rossander, L. and Hallberg, L. 1989. Iron absorption and phenolic compounds: Importance of different phenolic structures. Eur. J. Clin. Nutr. 43: 547-558.
2. deMan, J.M. 1989. Vitamins. Ch. 9 in Principles of Food Chemistry, Second Edition, J.M. deMan (Ed.), p. 347-353. Van Nostrand Reinhold, New York.
3. Elkins, E.R., Matthys, A., Lyon, R. and Huang, C.J. (1996). Characterization of commercially produced apple juice concentrate. J. Food Comp. Anal. 9: 43-56.
4. Glahn, R.P., Gangloff, M.B., Van Campen, D.R., Miller, D.D., Wien, E.M., and Norvell, W.A. 1995. Bathophenanthrolene disulfonic acid and sodium dithionite effectively remove surface bound iron from Caco-2 cell monolayers. J Nutr 125: 1833-1840.
5. Glahn R.P., Lai, C., Hsu, J., Thompson, J.F. and Van Campen D.R. 1998a. Decreased citrate improves iron availability from infant formula: Application of an in vitro digestion/Caco-2 Cell Culture Model. J. Nutr. 128: 257-264.
6. Glahn, R.P., Lee, O.A., Yeung, A., Goldman, M.I., and Miller, D.D. 1998b. Caco-2 cell ferritin formation predicts nonradiolabeled food iron availability in an in vitro digestion/Caco-2 cell culture model. J. Nutr. 128: 1555-1561.
7. Glahn, R.P., Wien, E.M., Van Campen, D.R., and Miller, D.D. (1996). Caco-2 cell iron uptake from meat and casein digests parallels in vivo studies: Use of a novel in vitro method for rapid estimation of iron bioavailability. J. Nutr 126: 332-339.
8. Haddad, P. 1977. Vitamin C content of commercial orange juices. J. Chem. Ed. 54: 192.
9. Hallberg, L., Brune, M, and Rossander, L. 1986. Effect of ascorbic acid on iron absorption from different types of meals. Studies with ascorbate-rich foods and synthetic ascorbic acid given in different amounts with different meals. Hum. Nutr. Appl. Nutr. 40A: 97-113.
10. Knezevic, Z., Gosak, D., Hraste, M., and Jalsenjak, I. 1998. Fluid-bed microencapsulation of ascorbic acid. J. Microencapsulation 15: 237-252.
11. Miller , D.D. and Berner, L.A. 1989. Is solubility in vitro a reliable predictor of iron bioavailability? Biol. Trace Element Res. 19: 11-24.
12. Motulsky, H. 1995. Comparing three or more means. Ch. 30 in Intuitive Biostatistics, H. Motulsky (Ed.), p.255-262. Oxford University Press, Oxford, NY.
13. Patkai, G. and Torok, S. 1989. The chemical composition of pressed and extracted apple juice. Acta Alimentaria 18: 153-166.