Schistosome Egg Granulomas and Hepatic Expression of TNF-α Are Dependent on Immune Priming during Parasite Maturation

Journal of Immunology

Volumn 158, Issue 1, 1997, Pages 301-307

  Leptak, Christopher L ^a   McKerrow, James H ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; BIOSYNTHESIS; GRANULOMA; GROWTH, DEVELOPMENT AND AGING; HUMAN; IMMUNIZATION; IMMUNOLOGY; INFANT; LIVER; METABOLISM; MOUSE; PARASITOLOGY; PATHOLOGY; SCHISTOSOMA MANSONI;

ANIMALS; GRANULOMA; HUMANS; IMMUNIZATION; INFANT; LIVER; MICE; MICE, INBRED BALB C; SCHISTOSOMA MANSONI; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030639134     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Warren, K. S., E. O. Domingo, and R. B. Cowan. 1967. Granuloma formation around schistosome eggs as a manifestation of delayed hypersensitivity. J. Pathol. 51:735.
2. Amiri, P., R. M. Locksley, T. G. Parslow, M. Sadick, E. Rector, D. Ritter, and J. H. McKerrow. 1992. Tumour necrosis factor α restores granulomas and induces parasite egg-laying in schistosome-infected SCID mice. Nature 356:604.
3. Amsden, A. F., D. L. Boros, and A. T. Hood. 1980. Etiology of the liver granulomatous response in Schistosoma mansoni-infected athymic nude mice. Infect. Immun. 27:75.
4. Byram, J. E., and F. von Lichtenberg. 1977. Altered schistosome granuloma formation in nude mice. Am. J. Trop. Med. Hyg. 26:944.
5. Domingo, E. O., and K. S. Warren. 1968. The inhibition of granuloma formation around Schistosoma mansoni eggs. III. Heterologous anti-lymphocyte serum. Am. J. Pathol. 52:613.
6. Mathew, R. C., S. Ragheb, and D. Boros. 1990. Recombinant IL-2 therapy reverses diminished granulomatous responsiveness in anti-L3T4-treated, Schistosoma mansoni-infected mice. J. Immunol. 144:4356.
7. Pearce, E. J., A. Cheever, S. Leonard, M. Covalesky, R. Fernandezbotran, G. Kohler, and M. Kopf. 1996. Schistosoma mansoni in IL-4-deficient mice. Int. Immunol. 8:435.
8. Chensue, S. W., K. Warmington, J. Ruth, P. Lincoln, M.-C. Kuo, and S. L. Kunkel. 1994. Cytokine responses during mycobacterial and schistosomal antigen-induced pulmonary granuloma formation. Am. J. Pathol. 145:1105.
9. Flores Villaneuva, P. O., S. M. Chikunguwo, T. S. Harris, and M. J. Stadecker. 1993. Role of IL-10 on antigen-presenting cell function for schistosomal egg-specific monoclonal T helper cell responses in vitro and in vivo. J. Immunol. 151:3192.
10. Grzych, J.-M., E. Pearce, A. Cheever, Z. A. Caulada, P. Caspar, S. Hieny, F. Lewis, and A. Sher. 1991. Egg deposition is the major stimulus for the production of Th2 cytokines in murine schistosomiasis mansoni. J. Immunol. 146: 1322.
11. Joseph, A. L., and D. L. Boros. 1993. Tumor necrosis factor plays a role in Schistosoma mansoni egg-induced granulomatous inflammation. J. Immunol. 151:5461.
12. Metwali, A., D. Elliot, R. Mathew, A. Blum, and J. V. Weinstock. 1993. IL-2 contributes to the IL-5 response in granulomas from mice infected with Schistosoma mansoni. J. Immunol. 150:536.
13. Pearce, E. J., P. Caspar, J.-M. Grzych, F. A. Lewis, and A. Sher. 1991. Down-regulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth. Schistosoma mansoni. J. Exp. Med. 173:159.
14. + T lymphocytes correlates with down-regulation of Th1 cytokine synthesis in helminth infection. J. Immunol. 147:2713.
15. + Th2 response induced by Schistosoma mansoni eggs develop rapidly, through an early, transient, Th0-like stage. J. Immunol. 148:2283.
16. Wynn, T. A., I. Eltoum, A. W. Cheever, F. A. Lewis, W. C. Gause, and A. Sher. 1993. Analysis of cytokine mRNA expression during primary granuloma formation induced by eggs of Schistosoma mansoni. J. Immunol. 151:1430.
17. Chensue, S. W., K. S. Warmington, N. W. Lukacs, P. M. Lincoln, M. D. Burdick, R. M. Strieter, and S. L. Kunkel. 1995. Monocyte chemotactic protein expression during schistosome egg granuloma formation. Am. J. Pathol. 146:130.
18. Lukacs, N. W., S. L. Kunkel, R. M. Strieter, K. Warmington, and S. W. Chensue. 1993. The role of macrophage inflammatory protein 1 alpha in Schistosoma mansoni egg-induced granulomatous inflammation. J. Exp. Med. 177:1551.
19. Lukacs, N. W., S. L. Kunkel, R. M. Strieter, and S. W. Chensue. 1994. The role of chemokines in Schistosoma mansoni granuloma formation. Parasitol. Today 10:322.
20. Lukacs, N. W., S. W. Chensue, R. E. Smith, R. M. Strieter, K. Warmington, C. Wilke, and S. L. Kunkel. 1994. Production of monocyte chemoattractant protein-1 and macrophage inflammatory protein-1α by inflammatory granuloma fibroblasts. Am. J. Pathol. 144:711.
21. Sher, A., R. L. Coffman, S. Hieny, P. Scott, and A. W. Cheever. 1990. Interleukin 5 is required for the blood and tissue eosinophilia but not granuloma formation induced by infection with Schistosoma mansoni. Proc. Natl. Acad. Sci. USA 87:61.
22. Wynn, T. A., I. Eltoum, I. P. Oswald, A. W. Cheever, and A. Sher. 1994. Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology. J. Exp. Med. 179:1551.
23. Boros, D. L., and K. S. Warren. 1970. Delayed hypersensitivity granuloma formation and dermal reaction induced and elicited by a soluble factor isolated from Schistosoma mansoni eggs. J. Exp. Med. 132:488.
24. Cheever, A. W., M. E. Williams, T. A. Wynn, F. D. Finkelman, R. A. Seder, T. M. Cox, S. Hieny, P. Carpar, and A. Sher. 1994. Anti-IL-4 treatment of Schistosoma mansoni-infected mice inhibits development of T cells and non-B, non-T cells expressing Th2 cytokines while decreasing egg-induced hepatic fibrosis. J. Immunol. 153:753.
25. Chensue, S. W., P. D. Terebuh, K. S. Warmington, S. D. Hershey, H. L. Evanoff, S. L. Kunkel, and G. I. Higashi. 1992. Role of interleukin-4 and γ-interferon in Schistosoma mansoni egg-induced hypersensitivity granuloma formation: orchestration, relative contribution and relationship to macrophage function. J. Immunol. 148:900.
26. Florentino, D. F., A. Zlotnik, P. Vieira, T. R. Mosmann, M. Howard, K. Moore, and A. O'Garra. 1991. IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells. J. Immunol. 146:3444.
27. Fiorentino, D. F., A. Zlotnik, T. R. Mosmann, M. Howard, and A. O'Garra. 1991. IL-10 inhibits cytokine production by activated macrophages. J. Immunol. 147: 3815.
28. Flores Villanueva, P. O., H. Reiser, and M. J. Stadecker. 1994. Regulation of T helper cell responses in experimental murine schistosomiasis by IL-10: effect on expression of B7 and B7-2 costimulatory molecules by macrophages. J. Immunol. 153:5190.
29. Oswald, I. P., P. Caspar, D. Jankovic, T. A. Wynn, E. J. Pearce, and A. Sher. 1994. IL-12 inhibits Th2 cytokine responses induced by eggs from Schistosoma mansoni. J. Immunol. 153:1707.
30. + T-cell subsets. Proc. Natl. Acad. Sci. USA 91:18.
31. McKerrow, J. H., S. Pino-Heiss, R. Landquist, and Z. Werb. 1985. Purification and characterization of an elatinolytic proteinase secreted by cercariae of Schistosoma mansoni. J. Biol. Chem. 260:3703.
32. Lim, K. C., and D. Heynemann. 1972. Intramolluscan inter-trematode antagonism: a review of factors influencing the host-parasite system and its possible role in biological control. Adv. Parasitol. 10:191.
33. + splenic cells. Am. J. Trop. Med. Hyg. 40:66.
34. Reiner, S. L., S. Zhichun, D. B. Corry, and R. M. Locksley. 1993. Constructing polycompetitor cDNAs for quantitative PCR. J. Immunol. Methods 165:37.
35. McKerrow, J. H., and E. Sun. 1994. Hepatic schistosomiasis. In Progress in Liver Diseases, Vol. XII. J. L. Boyer and R. K. Ockner, eds. W. B. Saunders Co., Philadelphia, chapter 10.
36. Bickle, Q. D., M. J. Ford, and B. J. Andrews. 1983. Studies on the development of anti schistosomular surface antibodies by mice exposed to irradiated cercariae, adults and/or eggs of Schistosoma mansoni. Parasite Immunol. 5:499.
37. Dunne, D. W., Q. D. Bickle, A. E. Butterworth, and B. A. Richardson. 1987. The blocking of human antibody-dependent, eosinophil-mediated killing of Schistosoma mansoni schistosomula by monoclonal antibodies which cross-react with a polysaccharide-containing egg antigen. Parasitology 94:255.
38. Yi, X., P. Omer-Ali, C. Kelly, A. J. G. Simpson, and S. R. Smithers. 1986. IgM antibodies recognizing carbohydrate epitopes shared between schistosomula and miracidia of Schistosoma mansoni that block in vitro killing. J. Immunol. 137: 3946.
39. Lukacs, N. W., S. W. Chensue, R. M. Strieter, K. Warmington, and S. L. Kunkel. 1994. Inflammatory granuloma formation is mediated by TNF-α-inducible intercellular adhesion molecule-1. J. Immunol. 152:5883.
40. Ohmori, Y., L. Wyner, S. Narumi, D. Armstrong, M. Stoler, and T. A. Hamilton. 1993. Tumor necrosis factor-α induces cell type and tissue-specific expression of chemoattractant cytokines in vivo. Am. J. Pathol. 142:861.
41. Pichyangkul, S., P. Saengkrai, and H. K. Webster. 1994. Plasmodium falciparum pigment induces monocytes to release high levels of tumor necrosis factor-α and interleukin-1β. Am. J. Trop. Med. Hyg. 51:430.
42. Manthey, C. L., T. Kossmann, J. B. Allen, M. L. Corcoran, M. E. Brandes, and S. M. Wahl. Role of Kupffer cells in developing streptococcal cell wall granulomas. Am. J. Pathol. 140:1205.