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Volumn 62, Issue 16, 1998, Pages 1433-1441

Safety and tolerability of metrifonate in patients with Alzheimer's disease: Results of a maximum tolerated dose study

(7) Cutler, Neal R a Jhee, Stanford S a Cyrus, Pamela c Bieber, Florian b TanPiengco, Paul c Sramek, John J a Gulanski, Barbara b

a CALIFORNIA CLINICAL TRIALS (United States)

b BAYER CORPORATION (United States)

c NONE

Author keywords

Acetylcholinesterase inhibitor; Alzheimer's disease; Bridging studies; Maximum tolerated dose; Metrifonate

Indexed keywords

ACETYLCHOLINESTERASE; CHOLINESTERASE INHIBITOR; DICHLORVOS; METRIFONATE; PRODRUG;

ABDOMINAL PAIN; ADULT; AGED; ALZHEIMER DISEASE; ANOREXIA; ARTICLE; ASTHENIA; BLEEDING; BRADYCARDIA; CLINICAL ARTICLE; CLINICAL TRIAL; CONSTIPATION; DIARRHEA; DIGESTIVE SYSTEM FUNCTION DISORDER; DRUG BLOOD LEVEL; DRUG DOSE; DRUG SAFETY; DRY SKIN; DYSPEPSIA; DYSPHAGIA; ENZYME INHIBITION; ERYTHROCYTE; FEMALE; FLATULENCE; GAS CHROMATOGRAPHY; HEADACHE; HUMAN; LIQUID LIQUID EXTRACTION; MALE; MAXIMUM PERMISSIBLE DOSE; MUSCLE CRAMP; MYASTHENIA; NAUSEA; NECK PAIN; RASH; STEADY STATE; SWEATING; VERTIGO;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; CHOLINESTERASE INHIBITORS; COHORT STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; PRODRUGS; TRICHLORFON;

EID: 0032513106 PISSN: 00243205 EISSN: None Source Type: Journal
DOI: 10.1016/S0024-3205(98)00082-4 Document Type: Article

Times cited : (21)

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