Catalytic activities and substrate specificity of the human membrane type 4 matrix metalloproteinase catalytic domain

Journal of Biological Chemistry

Volumn 274, Issue 46, 1999, Pages 33043-33049

  Wang, Yahong ^a   Johnson, Adam R ^a   Ye, Qi Zhuang ^a,b   Dyer, Richard D ^a  

^a PFIZER INC   (United States)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

1,10 PHENANTHROLINE; CALCIUM ION; COLLAGEN TYPE 1; COLLAGEN TYPE 4; DIPEPTIDYL CARBOXYPEPTIDASE; DNA; EDETIC ACID; FIBRONECTIN; GELATIN; HYDROXAMIC ACID; LAMININ; MATRIX METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TUMOR NECROSIS FACTOR ALPHA; ZINC ION;

ARTICLE; BREAST CARCINOMA; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME PURIFICATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; ENZYMOLOGY; ESCHERICHIA COLI; HUMAN; PH; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; BINDING SITES; CHELATING AGENTS; CLONING, MOLECULAR; ENZYME ACTIVATION; ENZYME INHIBITORS; ENZYME PRECURSORS; ESCHERICHIA COLI; GELATIN; GELATINASES; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; MATRIX METALLOPROTEINASES; MATRIX METALLOPROTEINASES, MEMBRANE-ASSOCIATED; METALLOENDOPEPTIDASES; MOLECULAR SEQUENCE DATA; PROTEIN FOLDING; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; ZINC;

EID: 0032722873     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.46.33043     Document Type: Article

References (39)

1. Woessner, J. F., Jr. (1991) FASEB J. 5, 2145-2154
2. Massova, I., Kotra, L. P., Fridman, R., and Mobashery, S. (1998) FASEB J. 12, 1075-1095
3. Giambernardi, T. A., Grant, G. M., Taylor, G. P., Hay, R. J., Maher, V. M., McCormick, J. J., and Klebe, R. J. (1999) Matrix Biol. 16, 483-496
4. Coussens, L. M., and Werb, Z. (1996) Chem. Biol. 3, 895-904
5. Rudolph-Owen, L. A., Chan, R., Muller, W. J., and Matrisian, L. M. (1998) Cancer Res. 58, 5500-5506
6. Walakovits, L. A., Moore, V. L., Bhardwaj, N., Gallick, G. S., and Lark, M. W. (1992) Arthritis Rheum. 35, 35-42
7. Dollery, C. M., McEwan, J. R., and Henney, A. M. (1995) Circ. Res. 77, 863-868
8. Sato, H., Takino, T., Okada, Y., Cao, J., Shinagawa, A., Yamamoto, E., and Seiki, M. (1994) Nature 370, 61-65
9. Will, H., and Hinzmann, B. (1995) Eur. J. Biochem. 231, 602-608
10. Takino, T., Sato, H., Shinagawa, A., and Seiki, M. (1995) J. Biol. Chem. 270, 23013-23020
11. Puente, X. S., Pendás, A. M., Llano, E., Velasco, G., and López-Otín, C. (1996) Cancer Res. 56, 944-949
12. Llano, E., Pendás, A. M., Freije, J. P., Nakano, A., Knäuper, V., Murphy, G., and López-Otín, C. (1999) Cancer Res. 59, 2570-2576
13. Shofuda, K., Yasumitsu, H., Nishihashi, A., Miki, K., and Miyazaki, K. (1997) J. Biol. Chem. 272, 9749-9754
14. Cao, J., Sato, H., Takino, T., and Seiki, M. (1995) J. Biol. Chem. 270, 801-805
15. Pei, D., and Weiss, S. (1996) J. Biol. Chem. 271, 9135-9140
16. Will, H., Atkinson, S. J., Butler, G. S., Smith, B., and Murphy, G. (1996) J. Biol. Chem. 271, 17119-17123
17. Strongin, A. Y., Collier, I., Bannikov, G., Marmer, B. L., Grant, G. A., and Goldberg, G. I. (1995) J. Biol. Chem. 270, 5331-5338
18. Ye, Q.-Z., Johnson, L. L., Hupe, D. J., and Baragi, V. (1992) Biochemistry 31, 11231-11235
19. Ye, Q.-Z., Johnson, L. L., Yu, A. E., and Hupe, D. J. (1995) Biochemistry 34, 4702-4708
20. Ye, Q.-Z., Hupe, D., and Johnson, L. (1996) Curr. Med. Chem. 3, 407-418
21. Kröger, M., and Tschesche, H. (1997) Gene 196, 175-190
22. Mucha, A., Cuniasse, P., Kannan, R., Beau, F., Yiotakis, A., Basset, P., and Dive, V. (1998) J. Biol. Chem. 273, 2763-2768
23. Becker, J. W., Marcy, A. I., Rokosz, L. L., Axel, M. G., Burbaum, J. J., Fitzgerald, P. M. D., Cameron, P. M., Esser, C. K., Hagmann, W. K., Hermes, J. D., and Springer, J. P. (1995) Protein Sci. 4, 1966-1976
24. VanDoren, S. R., Kurochkin, A. V., Hu, W., Ye, Q.-Z., Johnson, L. L., Hupe, D. J., and Zuiderweg, E. R. P. (1995) Protein Sci. 4, 2487-2498
25. Dhanaraj, V., Ye, Q.-Z., Johnson, L. L., Hupe, D. J., Ortwine, D. F., Dunbar, J. B., Jr., Rubin, J. R., Pavlovsky, A., Humblet, C., and Blundell, T. L. (1996) Structure 4, 375-386
26. Gomis-Rüth, F.-X., Maskos, K., Betz, M., Bergner, A., Huber, R., Suzuki, K., Yoshida, N., Nagase, H., Brew, K., Bourenkov, G. P., Bartunik, H., and Bode, W. (1997) Nature 389, 77-81
27. Knight, C. G., Willenbrock, F., and Murphy, G. (1992) FEBS Lett. 296, 263-266
28. Van Dyk, D. E., Marchaud, P., Bruckner, R. C., Fox, J. W., Jaffee, B. D., Gunyuzlu, P. L., Davis, G. L., Nurnberg, S., Covington, M., Decicco, C. P., Trzaskos, J. M., Magolda, R. L., and Copeland, R. A. (1997) Bioorg. Med. Chem. Lett. 7, 1219-1224
29. Patel, I. R., Attur, M. G., Patel, R. N., Stuchin, S. A., Abagyan, R. A., Abramson, S. B., and Amin, A. R. (1998) J. Immunol. 160, 4570-4578
30. Weingarten, H., Martin, R., and Feder, J. (1985) Biochemistry 24, 6730-6734
31. Liu, Y., Kati, W., Chen, C.-M., Tripathi, R., Molla, A., and Kohlbrener, W. (1999) Anal. Biochem. 267, 331-335
32. Ellis, K. J., and Morrison, J. F. (1982) Methods Enzymol. 87, 405-426
33. Harrison, R. K., Chang, B., Niedzwiecki, L., and Stein, R. L. (1992) Biochemistry 31, 10757-10762
34. Holman, C. M., Kan, C.-C., Gehring, M. R., and Van Wart, H. E. (1999) Biochemistry 38, 677-681
35. Grams, F., Crimmin, M, Hinnes, L., Huxley, P., Pieper, M., Tschesche, H., and Bode, W. (1995) Biochemistry 34, 14012-14020
36. Rasmussen, H. S., and McCann, P. P. (1997) Pharmacol. Ther. 75, 69-75
37. Caputo, C. B., Wolanin, D. J., Roberts, R. A., Sygowski, L. A., Patton, S. P., Caccese, R. G., Shaw, A., and DiPasquale, G. (1987) Biochem. Pharmacol. 36, 995-1002
38. MacPherson, L. J., Bayburt, E. K., Capparelli, M. P., Carroll, B. J., Goldstein, R., Justice, M. R., Zhu, L., Hu, S., Melton, R. A., Fryer, L., Goldberg, R. L., Doughty, J. R., Spirito, S., Blancuzzi, V., Wilson, D., O'Byrne, E. M., Ganu, V., and Parker, D. T. (1997) J. Med. Chem. 40, 2525-2532
39. Galardy, R. E. (1993) Drugs Future 18, 1109-1111