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Volumn 1, Issue 11, 1999, Pages 839-846

The molecular basis of MHC class II deficiency and transcriptional control of MHC class II gene expression

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; GAMMA INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

EID: 0032719308     PISSN: 12864579     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1286-4579(99)00235-X     Document Type: Article
Times cited : (25)

References (45)
  • 1
    • 0030480969 scopus 로고    scopus 로고
    • The CBP coactivator is a histone acetyltransferase
    • Bannister A.J., Kouzarides T. The CBP coactivator is a histone acetyltransferase. Nature. 384:1996;641-643.
    • (1996) Nature , vol.384 , pp. 641-643
    • Bannister, A.J.1    Kouzarides, T.2
  • 2
    • 0025762568 scopus 로고
    • Class II-antigen-negative patient and mutant B-cell lines represent at least three, and probably four, distinct genetic defects defined by complementation analysis
    • Benichou B., Strominger J.L. Class II-antigen-negative patient and mutant B-cell lines represent at least three, and probably four, distinct genetic defects defined by complementation analysis. Proc. Natl. Acad. Sci. USA. 88:1991;4285-4288.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 4285-4288
    • Benichou, B.1    Strominger, J.L.2
  • 3
    • 0022931249 scopus 로고
    • Pujol-Borrell R, Organ-specific autoimmunity: A (1986) overview
    • Bottazzo G.F., Todd I., Mirakian R., Belfiore A. Pujol-Borrell R, Organ-specific autoimmunity: a (1986) overview. Immunol. Rev. 94:1986;137-169.
    • (1986) Immunol. Rev. , vol.94 , pp. 137-169
    • Bottazzo, G.F.1    Todd, I.2    Mirakian, R.3    Belfiore, A.4
  • 4
    • 0029968925 scopus 로고    scopus 로고
    • Mice lacking the MHC class II transactivator (CIITA) show tissue-specific impairment of MHC class II expression
    • Chang C.H., Guerder S., Hong S.C., Van Ewijk W., Flavell R.A. Mice lacking the MHC class II transactivator (CIITA) show tissue-specific impairment of MHC class II expression. Immunity. 4:1996;167-178.
    • (1996) Immunity , vol.4 , pp. 167-178
    • Chang, C.H.1    Guerder, S.2    Hong, S.C.3    Van Ewijk, W.4    Flavell, R.A.5
  • 5
    • 0030951017 scopus 로고    scopus 로고
    • Importance of acidic, proline/serine/threonine-rich, and GTP-binding regions in the major histocompatibility complex class II transactivator: Generation of transdominant-negative mutants
    • Chin K.C., Li G.G., Ting J.P. Importance of acidic, proline/serine/threonine-rich, and GTP-binding regions in the major histocompatibility complex class II transactivator: generation of transdominant-negative mutants. Proc. Natl. Acad. Sci. USA. 94:1997;2501-2506.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 2501-2506
    • Chin, K.C.1    Li, G.G.2    Ting, J.P.3
  • 6
  • 7
    • 0022430251 scopus 로고
    • A trans-acting class II regulatory gene unlinked to the MHC controls expression of HLA class II genes
    • De Preval C., Lisowska-Grospierre B., Loche M., Griscelli C., Mach B. A trans-acting class II regulatory gene unlinked to the MHC controls expression of HLA class II genes. Nature. 318:1985;291-293.
    • (1985) Nature , vol.318 , pp. 291-293
    • De Preval, C.1    Lisowska-Grospierre, B.2    Loche, M.3    Griscelli, C.4    MacH, B.5
  • 8
    • 0027994698 scopus 로고
    • Functional complementation of MHC class II regulatory mutants by the purified X box binding protein RFX
    • Durand B., Kobr M., Reith W., Mach B. Functional complementation of MHC class II regulatory mutants by the purified X box binding protein RFX. Mol. Cell Biol. 14:1994;6839-6847.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 6839-6847
    • Durand, B.1    Kobr, M.2    Reith, W.3    MacH, B.4
  • 9
    • 0031055891 scopus 로고    scopus 로고
    • RFXAP, a novel subunit of the RFX DNA binding complex is mutated in MHC class II deficiency
    • Durand B., Sperisen P., Emery P., Barras E., Zufferey M., Mach B., Reith W. RFXAP, a novel subunit of the RFX DNA binding complex is mutated in MHC class II deficiency. EMBO J. 16:1997;1045-1055.
    • (1997) EMBO J. , vol.16 , pp. 1045-1055
    • Durand, B.1    Sperisen, P.2    Emery, P.3    Barras, E.4    Zufferey, M.5    MacH, B.6    Reith, W.7
  • 11
    • 0030832267 scopus 로고    scopus 로고
    • The class II trans- activator CIITA interacts with the TBP-associated factor TAF II 32
    • Fontes J.D., Jiang B., Peterlin B.M. The class II trans- activator CIITA interacts with the TBP-associated factor TAF II 32. Nucleic Acids Res. 25:1997;2522-2528.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 2522-2528
    • Fontes, J.D.1    Jiang, B.2    Peterlin, B.M.3
  • 12
    • 0032937881 scopus 로고    scopus 로고
    • Interactions between the class II transactivator and CREB binding protein increase transcription of major histocompatibility complex class II genes
    • Fontes J.D., Kanazawa S., Jean D., Peterlin B.M. Interactions between the class II transactivator and CREB binding protein increase transcription of major histocompatibility complex class II genes. Mol. Cell Biol. 19:1999;941-947.
    • (1999) Mol. Cell Biol. , vol.19 , pp. 941-947
    • Fontes, J.D.1    Kanazawa, S.2    Jean, D.3    Peterlin, B.M.4
  • 13
    • 0032192508 scopus 로고    scopus 로고
    • The RFX complex is crucial for the constitutive and CIITA-mediated transactivation of MHC class I and beta2-microglobulin genes
    • Gobin S.J., Peijnenburg A., Van Eggermond M., Van Zutphen M., Van Den Berg R., Van Den Elsen P.J. The RFX complex is crucial for the constitutive and CIITA-mediated transactivation of MHC class I and beta2-microglobulin genes. Immunity. 9:1998;531-541.
    • (1998) Immunity , vol.9 , pp. 531-541
    • Gobin, S.J.1    Peijnenburg, A.2    Van Eggermond, M.3    Van Zutphen, M.4    Van Den Berg, R.5    Van Den Elsen, P.J.6
  • 14
    • 0031136958 scopus 로고    scopus 로고
    • IFN- regulatory factor-1 plays a central role in the regulation of the expression of class I and II MHC genes in vivo
    • Hobart M., Ramassar V., Goes N., Urmson J., Halloran P.F. IFN- regulatory factor-1 plays a central role in the regulation of the expression of class I and II MHC genes in vivo. J. Immunol. 158:1997;4260-4269.
    • (1997) J. Immunol. , vol.158 , pp. 4260-4269
    • Hobart, M.1    Ramassar, V.2    Goes, N.3    Urmson, J.4    Halloran, P.F.5
  • 15
    • 0025870067 scopus 로고
    • In vivo footprinting of MHC class II genes: Bare promoters in the bare lymphocyte syndrome
    • Kara C.J., Glimcher L.H. In vivo footprinting of MHC class II genes: bare promoters in the bare lymphocyte syndrome. Science. 252:1991;709-712.
    • (1991) Science , vol.252 , pp. 709-712
    • Kara, C.J.1    Glimcher, L.H.2
  • 16
    • 0027173726 scopus 로고
    • Developmental and cytokine-mediated regulation of MHC class II gene promoter occupancy in vivo
    • Kara C.J., Glimcher L.H. Developmental and cytokine-mediated regulation of MHC class II gene promoter occupancy in vivo. J. Immunol. 150:1993;4934-4942.
    • (1993) J. Immunol. , vol.150 , pp. 4934-4942
    • Kara, C.J.1    Glimcher, L.H.2
  • 17
    • 0027446688 scopus 로고
    • Major histocompatibility complex class II deficiency: Clinical manifestations, immunologic features, and outcome
    • Klein C., Lisowska Grospierre B., Ledeist F., Fischer A., Griscelli C. Major histocompatibility complex class II deficiency: clinical manifestations, immunologic features, and outcome. J. Pediatr. 123:1993;921-928.
    • (1993) J. Pediatr. , vol.123 , pp. 921-928
    • Klein, C.1    Lisowska Grospierre, B.2    Ledeist, F.3    Fischer, A.4    Griscelli, C.5
  • 18
    • 0031773473 scopus 로고    scopus 로고
    • Involvement of CREB binding protein in expression of major histocompatibility complex class II genes via interaction with the class II transactivator
    • Kretsovali A., Agalioti T., Spilianakis C., Tzortzakaki E., Merika M., Papamatheakis J. Involvement of CREB binding protein in expression of major histocompatibility complex class II genes via interaction with the class II transactivator. Mol. Cell Biol. 18:1998;6777-6783.
    • (1998) Mol. Cell Biol. , vol.18 , pp. 6777-6783
    • Kretsovali, A.1    Agalioti, T.2    Spilianakis, C.3    Tzortzakaki, E.4    Merika, M.5    Papamatheakis, J.6
  • 19
    • 0030586657 scopus 로고    scopus 로고
    • Stat1 alpha expression is involved in IFN-gamma induction of the class II transactivator and class II MHC genes
    • Lee Y.J., Benveniste E.N. Stat1 alpha expression is involved in IFN-gamma induction of the class II transactivator and class II MHC genes. J. Immunol. 157:1996;1559-1568.
    • (1996) J. Immunol. , vol.157 , pp. 1559-1568
    • Lee, Y.J.1    Benveniste, E.N.2
  • 21
    • 0031572574 scopus 로고    scopus 로고
    • Formation of a regulatory factor X/X2 box-binding protein/nuclear factor-Y multiprotein complex on the conserved regulatory regions of HLA class II genes
    • Louis-Plence P., Moreno C., Boss J. Formation of a regulatory factor X/X2 box-binding protein/nuclear factor-Y multiprotein complex on the conserved regulatory regions of HLA class II genes. J. Immunol. 159:1997;3899-3909.
    • (1997) J. Immunol. , vol.159 , pp. 3899-3909
    • Louis-Plence, P.1    Moreno, C.2    Boss, J.3
  • 22
    • 0028842529 scopus 로고
    • Interferon (IFN) beta acts downstream of IFN-gamma-induced class II transactivator messenger RNA accumulation to block major histocompatibility complex class II gene expression and requires the 48-kD DNA-binding protein, ISGF3-gamma
    • Lu H.T., Riley J.L., Babcock G.T., Huston M., Stark G.R., Boss J.M., Ransohoff R.M. Interferon (IFN) beta acts downstream of IFN-gamma-induced class II transactivator messenger RNA accumulation to block major histocompatibility complex class II gene expression and requires the 48-kD DNA-binding protein, ISGF3-gamma. J. Exp. M. 182:1995;1517-1525.
    • (1995) J. Exp. M , vol.182 , pp. 1517-1525
    • Lu, H.T.1    Riley, J.L.2    Babcock, G.T.3    Huston, M.4    Stark, G.R.5    Boss, J.M.6    Ransohoff, R.M.7
  • 25
    • 0031570503 scopus 로고    scopus 로고
    • Regulatory factor X, a bare lymphocyte syndrome transcription factor, is a multimeric phosphoprotein complex
    • Moreno C.S., Rogers E.M., Brown J.A., Boss J.M. Regulatory factor X, a bare lymphocyte syndrome transcription factor, is a multimeric phosphoprotein complex. J. Immunol. 158:1997;5841-5848.
    • (1997) J. Immunol. , vol.158 , pp. 5841-5848
    • Moreno, C.S.1    Rogers, E.M.2    Brown, J.A.3    Boss, J.M.4
  • 26
    • 0030949011 scopus 로고    scopus 로고
    • Expression of MHC class II molecules in different cellular and functional compartments is controlled by differential usage of multiple promoters of the transactivator CIITA
    • Muhlethaler-Mottet A., Otten L.A., Steimle V., Mach B. Expression of MHC class II molecules in different cellular and functional compartments is controlled by differential usage of multiple promoters of the transactivator CIITA. EMBO J. 16:1997;2851-2860.
    • (1997) EMBO J. , vol.16 , pp. 2851-2860
    • Muhlethaler-Mottet, A.1    Otten, L.A.2    Steimle, V.3    MacH, B.4
  • 27
    • 0032006255 scopus 로고    scopus 로고
    • Activation of the MHC class II transactivator CIITA by interferon-gamma requires cooperative interaction between Stat1 and USF-1
    • Muhlethaler-Mottet A., Di Berardino W., Otten L.A., Mach B. Activation of the MHC class II transactivator CIITA by interferon-gamma requires cooperative interaction between Stat1 and USF-1. Immunity. 8:1998;157-166.
    • (1998) Immunity , vol.8 , pp. 157-166
    • Muhlethaler-Mottet, A.1    Di Berardino, W.2    Otten, L.A.3    MacH, B.4
  • 28
    • 0031065145 scopus 로고    scopus 로고
    • TGF-beta attenuates the class II transactivator and reveals an accessory pathway of IFN-gamma action
    • Nandan D., Reiner N.E. TGF-beta attenuates the class II transactivator and reveals an accessory pathway of IFN-gamma action. J. Immunol. 158:1997;1095-1101.
    • (1997) J. Immunol. , vol.158 , pp. 1095-1101
    • Nandan, D.1    Reiner, N.E.2
  • 29
    • 0031937604 scopus 로고    scopus 로고
    • Quantitative control of MHC class II expression by the transactivator CIITA
    • Otten L.A., Steimle V., Bontron S., Mach B. Quantitative control of MHC class II expression by the transactivator CIITA. Eur. J. Immunol. 28:1998;473-478.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 473-478
    • Otten, L.A.1    Steimle, V.2    Bontron, S.3    MacH, B.4
  • 30
    • 0031906211 scopus 로고    scopus 로고
    • Identification of distinct regions of 5' flanking DNA that mediate constitutive, IFN-gamma, STAT1, and TGF-beta-regulated expression of the class II transactivator gene
    • Piskurich J.F., Wang Y., Linhoff M.W., White L.C., Ting J.P. Identification of distinct regions of 5' flanking DNA that mediate constitutive, IFN-gamma, STAT1, and TGF-beta-regulated expression of the class II transactivator gene. J. Immunol. 160:1998;233-240.
    • (1998) J. Immunol. , vol.160 , pp. 233-240
    • Piskurich, J.F.1    Wang, Y.2    Linhoff, M.W.3    White, L.C.4    Ting, J.P.5
  • 31
    • 0032908350 scopus 로고    scopus 로고
    • Two distinct gamma interferon-inducible promoters of the major histocompatibility complex class II transactivator gene are differentially regulated by STAT1, interferon regulatory factor 1, and transforming growth factor beta
    • Piskurich J.F., Linhoff M.W., Wang Y., Ting J.P.Y. Two distinct gamma interferon-inducible promoters of the major histocompatibility complex class II transactivator gene are differentially regulated by STAT1, interferon regulatory factor 1, and transforming growth factor beta. Mol. Cell Biol. 19:1999;431-440.
    • (1999) Mol. Cell Biol , vol.19 , pp. 431-440
    • Piskurich, J.F.1    Linhoff, M.W.2    Wang, Y.3    Ting, J.P.Y.4
  • 32
    • 0027998318 scopus 로고
    • Cooperative binding between factors RFX and X2bp to the X and X2 boxes of MHC class II promoters
    • Reith W., Kobr M., Emery P., Durand B., Siegrist C.A., Mach B. Cooperative binding between factors RFX and X2bp to the X and X2 boxes of MHC class II promoters. J. Biol. Chem. 269:1994;20020-20025.
    • (1994) J. Biol. Chem. , vol.269 , pp. 20020-20025
    • Reith, W.1    Kobr, M.2    Emery, P.3    Durand, B.4    Siegrist, C.A.5    MacH, B.6
  • 33
    • 0028054792 scopus 로고
    • Function of major histocompatibility complex class II promoters requires cooperative binding between factors RFX and NF-Y
    • Reith W., Siegrist C.A., Durand B., Barras E., Mach B. Function of major histocompatibility complex class II promoters requires cooperative binding between factors RFX and NF-Y. Proc. Natl. Acad. Sci. USA. 91:1994;554-558.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 554-558
    • Reith, W.1    Siegrist, C.A.2    Durand, B.3    Barras, E.4    MacH, B.5
  • 34
    • 0029048828 scopus 로고
    • Activation of class II MHC genes requires both the X box and the class II transactivator (CIITA)
    • Riley J.L., Westerheide S.D., Price J.A., Brown J.A., Boss J.M. Activation of class II MHC genes requires both the X box and the class II transactivator (CIITA). Immunity. 2:1995;533-543.
    • (1995) Immunity , vol.2 , pp. 533-543
    • Riley, J.L.1    Westerheide, S.D.2    Price, J.A.3    Brown, J.A.4    Boss, J.M.5
  • 35
    • 0030924770 scopus 로고    scopus 로고
    • Specific complex formation between the type II bare lymphocyte syndrome-associated transactivators CIITA and RFX5
    • Scholl T., Mahanta S.K., Strominger J.L. Specific complex formation between the type II bare lymphocyte syndrome-associated transactivators CIITA and RFX5. Proc. Natl. Acad. Sci. USA. 94:1997;6330-6334.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 6330-6334
    • Scholl, T.1    Mahanta, S.K.2    Strominger, J.L.3
  • 36
    • 0026556640 scopus 로고
    • Genetic complexity of regulatory mutants defective for HLA class-II gene-expression
    • Seidl C., Saraiya C., Osterweil Z., Fu Y.P., Lee J.S. Genetic complexity of regulatory mutants defective for HLA class-II gene-expression. J. Immunol. 148:1992;1576-1584.
    • (1992) J. Immunol. , vol.148 , pp. 1576-1584
    • Seidl, C.1    Saraiya, C.2    Osterweil, Z.3    Fu, Y.P.4    Lee, J.S.5
  • 37
    • 0028071614 scopus 로고
    • Developmental extinction of major histocompatibility complex class II gene expression in plasmocytes is mediated by silencing of the transactivator gene CIITA
    • Silacci P., Mottet A., Steimle V., Reith W., Mach B. Developmental extinction of major histocompatibility complex class II gene expression in plasmocytes is mediated by silencing of the transactivator gene CIITA. J. Exp. M. 180:1994;1329-1336.
    • (1994) J. Exp. M , vol.180 , pp. 1329-1336
    • Silacci, P.1    Mottet, A.2    Steimle, V.3    Reith, W.4    MacH, B.5
  • 38
    • 0027490172 scopus 로고
    • Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)
    • Steimle V., Otten L.A., Zufferey M., Mach B. Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome). Cell. 75:1993;135-146.
    • (1993) Cell , vol.75 , pp. 135-146
    • Steimle, V.1    Otten, L.A.2    Zufferey, M.3    MacH, B.4
  • 39
    • 0028142430 scopus 로고
    • Regulation of MHC class II expression by interferon-gamma mediated by the transactivator gene CIITA
    • Steimle V., Siegrist C., Mottet A., Lisowska-Grospierre B., Mach B. Regulation of MHC class II expression by interferon-gamma mediated by the transactivator gene CIITA. Science. 265:1994;106-109.
    • (1994) Science , vol.265 , pp. 106-109
    • Steimle, V.1    Siegrist, C.2    Mottet, A.3    Lisowska-Grospierre, B.4    MacH, B.5
  • 40
    • 11944266638 scopus 로고
    • A novel DNA binding regulatory factor is mutated in primary MHC class II deficiency (Bare Lymphocyte Syndrome)
    • Steimle V., Durand B., Barras E., Zufferey M., Hadam M.R., Mach B., Reith W. A novel DNA binding regulatory factor is mutated in primary MHC class II deficiency (Bare Lymphocyte Syndrome). Genes Dev. 9:1995;1021-1032.
    • (1995) Genes Dev. , vol.9 , pp. 1021-1032
    • Steimle, V.1    Durand, B.2    Barras, E.3    Zufferey, M.4    Hadam, M.R.5    MacH, B.6    Reith, W.7
  • 41
    • 0026316475 scopus 로고
    • Stereospecific alignment of the X and Y elements is required for major histocompatibility complex class II DRA promoter function
    • Vilen B.J., Cogswell J.P., Ting J.P. Stereospecific alignment of the X and Y elements is required for major histocompatibility complex class II DRA promoter function. Mol. Cell. Biol. 11:1991;2406-2415.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 2406-2415
    • Vilen, B.J.1    Cogswell, J.P.2    Ting, J.P.3
  • 43
    • 0033034675 scopus 로고    scopus 로고
    • CIITA-induced occupation of MHC class II promoters is independant of the cooperative stabilization of the promoter-bound multi-protein complexes
    • Villard J., Muhlethaler-Mottet A., Bontron S., Mach B., Reith W. CIITA-induced occupation of MHC class II promoters is independant of the cooperative stabilization of the promoter-bound multi-protein complexes. Int. Immunol. 11:1999;461-469.
    • (1999) Int. Immunol. , vol.11 , pp. 461-469
    • Villard, J.1    Muhlethaler-Mottet, A.2    Bontron, S.3    MacH, B.4    Reith, W.5
  • 44
    • 0032568658 scopus 로고    scopus 로고
    • CIITA stimulation of transcription factor binding to major histocompatibility complex class II and associated promoters in vivo
    • Wright K., Chin K., Linhoff M., Skinner C., Brown J., Boss J., Stark G., Ting J. CIITA stimulation of transcription factor binding to major histocompatibility complex class II and associated promoters in vivo. Proc. Natl. Acad. Sci. USA. 95:1998;6267-6272.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 6267-6272
    • Wright, K.1    Chin, K.2    Linhoff, M.3    Skinner, C.4    Brown, J.5    Boss, J.6    Stark, G.7    Ting, J.8
  • 45
    • 0029075521 scopus 로고
    • Human MHC class II gene transcription directed by the carboxyl terminus of CIITA, one of the defective genes in type II MHC combined immune deficiency
    • Zhou H., Glimcher L.H. Human MHC class II gene transcription directed by the carboxyl terminus of CIITA, one of the defective genes in type II MHC combined immune deficiency. Immunity. 2:1995;545-553.
    • (1995) Immunity , vol.2 , pp. 545-553
    • Zhou, H.1    Glimcher, L.H.2


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