Sympathetic inhibition, leptin, and uncoupling protein subtype expression in normal fasting rats

American Journal of Physiology - Endocrinology and Metabolism

Volumn 277, Issue 4 40-4, 1999, Pages

  Sivitz, W I ^a,b   Fink, B D ^a   Morgan, D A ^a   Fox, J M ^a   Donohoue, P A ^a   Haynes, W G ^a  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

Author keywords

Insulin sensitivity; Sympathetic activity

Indexed keywords

CATECHOLAMINE; GLUCOSE; INSULIN; LEPTIN; MESSENGER RNA; METIROSINE METHYL ESTER; OXIDOPAMINE; UNCOUPLING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; DIET RESTRICTION; INSULIN SENSITIVITY; LIPOLYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SYMPATHETIC NERVE; THERMOGENESIS;

EID: 0032713705     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.1999.277.4.e668     Document Type: Article

References (35)

1. Avakian, E., and S. Horvath. Starvation suppresses sympathoadrenal medullary response to cold exposure in rats. Am. J. Physiol. 241 (Endocrinol. Metab. 4): E316-E320, 1981.
2. Boss, O., S. Samec, F. Kuhne, P. Bijlenga, F. Assimacopoulos-Jeannet, J. Seydoux, J. P. Giacobino, and P. Muzzin. Uncoupling protein-3 expression in rodent skeletal muscle is modulated by food intake but not by changes in environmental temperature. J. Biol. Chem. 273: 5-8, 1998.
3. Chomczynski, P., and N. Sacchi. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159, 1987.
4. Collins, S., and R. S. Surwit. Pharmacologic manipulation of ob expression in a dietary model of obesity. J. Biol. Chem. 271: 9437-9440, 1996.
5. Collins, S., C. M. Kuhn, A. E. Petro, A. G. Swick, B. A. Chrunyk, and R. S. Surwit. Role of leptin in fat regulation. Nature 380: 677, 1996.
6. Commins, S. P., P. M. Watson, M. A. Padgett, A. Dudley, G. Argyropoulos, and T. W. Gettys. Induction of uncoupling protein expression in brown and white adipose tissue by leptin. Endocrinology 140: 292-300, 1999.
7. DeLuigi, A., L. Terreni, T. M. Sironi, and M. G. DeSimoni. The sympathetic nervous system tonically inhibits peripheral interleukin-1β and interleukin-6 induction by central lipopolysaccharide. Neuroscience 83: 1245-1250, 1998.
8. Deng, C., M. Moinat, L. Curtis, A. Nadakal, F. Preitner, O. Boss, F. Assimacopoulos-Jeannet, J. Seydoux, and J. P. Giacobino. Effects of beta-adrenoceptor subtype stimulation on obese gene messenger ribonucleic acid and on leptin secretion in mouse brown adipocytes differentiated in culture. Endocrinology 138: 548-552, 1997.
9. Desautels, M., and J. Himms-Hagen. Roles of noradrenaline and protein synthesis in the cold-induced increase in purine nucleotide bonding by brown adipose tissue mitochondria. Can. J. Biochem. 57: 968-976, 1979.
10. Dunbar, J. C., Y. Hu, and H. Lu. Intracerebroventricular leptin increases lumbar and renal sympathetic nerve activity and blood pressure in normal rats. Diabetes 46: 2040-2043, 1997.
11. Flaim, K. E., J. M. Horowitz, and B. A. Horwitz. Functional and anatomical characteristics of the nerve-brown adipose interaction in the rat. Pflügers Arch. 365: 9-14, 1976.
12. Haynes, W. G., D. A. Morgan, S. A. Walsh, A. L. Mark, and W. I. Sivitz. Receptor-mediated regional sympathetic nerve activation by leptin. J. Clin. Invest. 100: 270-278, 1997.
13. Haynes, W. G., D. A. Morgan, S. A. Walsh, W. I. Sivitz, A. K. Johnson, and A. L. Mark. Sympathetic activation by leptin is mediated by the hypothalamus (Abstract). FASEB J. 12: A65, 1998.
14. Himms-Hagen, J. Role of thermogenesis in the regulation of energy balance in relation to obesity. Can. J. Physiol. Pharmacol. 67: 394-401, 1988.
15. Itoh, M., and J. Gerich. Adrenergic modulation of pancreatic somatostatin, insulin and glucagon secretion: evidence for differential sensitivity of islet A, B, and D cells. Metabolism 31: 715-720, 1982.
16. Klaus, S., L. Casteilla, F. Bouillaud, and D. Ricquier. The uncoupling protein UCP: a membraneous mitochondrial ion carrier exclusively expressed in brown adipose tissue. Int. J. Biochem. 23: 791-801, 1991.
17. Kuhn, C., R. Surwit, and M. Feinglos. Glipizide stimulates sympathetic outflow in diabetes-prone mice. Life Sci. 56: 661-666, 1994.
18. Lerach, H., D. Diamond, J. M. Wozney, and H. Boedtker. RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination. Biochemistry 16: 4743-4751, 1977.
19. 3-Adrenergic-mediated suppression of leptin gene expression in rats. Am. J. Physiol. 272 (Endocrinol. Metab. 35): E1031-E1036, 1997.
20. Mantzoros, C. S., D. Qu, R. C. Frederich, V. S. Susulic, B. B. Lowell, E. Maratos-Flier, and J. S. Flier. Activation of beta(3) adrenergic receptors suppresses leptin expression and mediates a leptin-independent inhibition of food intake in mice. Diabetes 45: 909-914, 1996.
21. Morgan, D. A., E. A. Anderson, and A. L. Mark. Renal sympathetic nerve activity is increased in obese Zucker rats. Hypertension 25: 834-838, 1995.
22. Morgan, D. A., T. W. Balon, B. H. Ginsberg, and A. L. Mark. Nonuniform regional sympathetic nerve responses to hyperinsulinemia in rats. Am. J. Physiol. 264 (Regulatory Integrative Comp. Physiol. 33): R423-R427, 1993.
23. Narimiya, M., H. Yamada, I. Matsuba, Y. Ikeda, T. Tanese, and M. Abe. Adrenergic modulation of insulin and glucagon secretion from the isolated perfused rat pancreas. Endocrinol. Jpn. 28: 281-292, 1981.
24. Radaelli, A., L. Micoli, S. Perlini, G. Bolla, I. Mori, G. Mancia, and U. Ferrari. Lack of autonomic contributions to tonic nitric oxide-mediated vasodilation in unanesthetized free-moving rats. J. Hypertens. 16: 55-61, 1998.
25. Rayner, D. V., E. Simon, J. S. Duncan, and P. Trayhurn. Hyperleptinaemia in mice induced by administration of the tyrosine hydroxylase inhibitor α-methyl-p-tyrosine. FEBS Lett. 429: 395-398, 1998.
26. Rothwell, N., and M. Stock. A role for brown adipose tissue in diet-induced thermogenesis. Nature 281: 31-35, 1979.
27. Sambrook, J., J. M. Fritsch, and T. Maniatis. Molecular Cloning. Cold Springs Harbor, NY: Cold Springs Harbor Laboratory, 1989,
28. Scarpace, P. J., M. Matheny, B. H. Pollock, and N. Tumer. Leptin increases uncoupling protein expression and energy expenditure. Am. J. Physiol. 273 (Endocrinol. Metab. 36): E226-E230, 1997.
29. Sivitz, W. I., H. L. Bailey, and P. Donohoue. Rat adipose ob mRNA levels in states of altered circulating glucose and insulin. Biochem. Biophys. Res. Commun. 220: 520-525, 1996.
30. Sivitz, W. I., S. Walsh, D. Morgan, P. Donohoue, W. Haynes, and R. L. Leibel. Plasma leptin in diabetic and insulin-treated diabetic and normal rats. Metabolism 47: 584-591, 1998.
31. Stock, M., and N. Rothwell. Factors influencing brown fat and the capacity for diet-induced thermogenesis. Int. J. Obes. 9, Suppl. 2: 9-15, 1985.
32. Thoenen, H., and J. P. Tranzer. The pharmacology of 6-hydroxydopamime. Annu. Rev. Pharmacol. Toxicol. 13: 169-180, 1973.
33. Tranzer, J. P., and H. Thoenen. An electron microscopic study of selective, acute degeneration of sympathetic nerve terminals after administration of 6-hydroxydopamine. Experientia 24: 155-156, 1968.
34. Yoshida, T., H. Nishioka, Y. Nakamura, and M. Kondo. Reduced norepinephrine turnover in mice with monosodium glutamate-induced obesity. Metabolism 33: 1060-1063, 1984.
35. Zimmermann, R. C., L. Krahn, G. Klee, P. Delgado, S. J. Ory, and S. C. Lin. Inhibition of presynaptic catecholamine synthesis with alpha-methyl-para-tyrosine attenuates nocturnal melatonin secretion in humans. J. Clin. Endocrinol. Metab. 79: 1110-1114, 1994.