3-Hydroxykynurenine potentiates quinolinate but not NMDA toxicity in the rat striatum

European Journal of Neuroscience

Volumn 11, Issue 11, 1999, Pages 3857-3863

  Guidetti, Paolo ^a   Schwarcz, Robert ^a  

^a MARYLAND PSYCHIATRIC RESEARCH CENTER   (United States)

Author keywords

Excitotoxic injury; Kynurenine pathway; L 3 hydroxykynurenine; NMDA receptors; Quinolinate

Indexed keywords

2 AMINO 4 METHYL 5 PHOSPHONO 3 PENTENOIC ACID; 3 HYDROXYKYNURENINE; N METHYL DEXTRO ASPARTIC ACID; QUINOLINIC ACID; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CORPUS STRIATUM; DOPAMINERGIC NERVE CELL; IMMUNOHISTOCHEMISTRY; MALE; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT;

2-AMINO-5-PHOSPHONOVALERATE; AFFERENT PATHWAYS; ANIMALS; BENZENESULFONATES; CORPUS STRIATUM; DRUG SYNERGISM; ELECTRON TRANSPORT COMPLEX IV; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; FREE RADICAL SCAVENGERS; KYNURENINE; MALE; MOTOR ACTIVITY; N-METHYLASPARTATE; QUINOLINIC ACID; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; TYROSINE 3-MONOOXYGENASE;

EID: 0032698232     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.1999.00806.x     Document Type: Article

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