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Volumn 398, Issue , 1996, Pages 221-227

Kynurenic acid-enhancing and anti-ischemic effects of the potent kynurenine 3-hydroxylase inhibitor FCE 28833 in rodents

Author keywords

[No Author keywords available]

Indexed keywords

RODENTIA;

EID: 0030347302     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4613-0381-7_35     Document Type: Article
Times cited : (24)

References (25)
  • 1
    • 0028305047 scopus 로고
    • Inhibitors of kynurenine hydroxylase and kynureninase increase cerebral formation of kynurenate and have sedative and anticonvulsant activities
    • Carpenedo, R., Chiarugi, A., Russi, P., Lombardi, G., Carlá, V., Pellicciari, R., Mattioli, L., and Moroni, F., 1994, Inhibitors of kynurenine hydroxylase and kynureninase increase cerebral formation of kynurenate and have sedative and anticonvulsant activities. Neurosci. 61:237.
    • (1994) Neurosci. , vol.61 , pp. 237
    • Carpenedo, R.1    Chiarugi, A.2    Russi, P.3    Lombardi, G.4    Carlá, V.5    Pellicciari, R.6    Mattioli, L.7    Moroni, F.8
  • 2
    • 0028784927 scopus 로고
    • Systemic administration of kainate induces marked increases of endogenous kynurenic acid in various brain regions and plasma of rats
    • Baran, H., Gramer, M., Hönack, D., and Löscher, W., 1995, Systemic administration of kainate induces marked increases of endogenous kynurenic acid in various brain regions and plasma of rats. Eur. J. Pharmacol., 286:167.
    • (1995) Eur. J. Pharmacol. , vol.286 , pp. 167
    • Baran, H.1    Gramer, M.2    Hönack, D.3    Löscher, W.4
  • 3
    • 0029061019 scopus 로고
    • Quinolinic acid accumulation and functional deficits following experimental spinal cord injury
    • Blight, A.R., Cohen, T.I., Saito, K., and Heyes, M.P., 1995, Quinolinic acid accumulation and functional deficits following experimental spinal cord injury, Brain 118:735.
    • (1995) Brain , vol.118 , pp. 735
    • Blight, A.R.1    Cohen, T.I.2    Saito, K.3    Heyes, M.P.4
  • 4
    • 0011870555 scopus 로고
    • Studies on the biological activity of nicotinylalanine, an analogue of kynurenine
    • Decker, R.H., Brown, R.R., and Price, J.M., 1963, Studies on the biological activity of nicotinylalanine, an analogue of kynurenine, J. Biol. Chem. 238:1049.
    • (1963) J. Biol. Chem. , vol.238 , pp. 1049
    • Decker, R.H.1    Brown, R.R.2    Price, J.M.3
  • 5
    • 0025042430 scopus 로고
    • Delayed increases in regional brain quinolinic acid follow transient ischemia in the gerbil
    • Heyes, M.P., and Nowak Jr., T.S., 1990, Delayed increases in regional brain quinolinic acid follow transient ischemia in the gerbil. J. Cereb. Blood Flow Metab. 10:660.
    • (1990) J. Cereb. Blood Flow Metab. , vol.10 , pp. 660
    • Heyes, M.P.1    Nowak Jr., T.S.2
  • 7
    • 0025808038 scopus 로고
    • Focal injection of aminooxyacetic acid produces seizures and lesions in rat hippocampus: Evidence for mediation by NMDA receptors
    • McMaster, O.G., Du, F., French, E.D., and Schwarcz, R., (1991) Focal injection of aminooxyacetic acid produces seizures and lesions in rat hippocampus: evidence for mediation by NMDA receptors. Exp. Neurol. 113:378.
    • (1991) Exp. Neurol. , vol.113 , pp. 378
    • McMaster, O.G.1    Du, F.2    French, E.D.3    Schwarcz, R.4
  • 8
    • 0026497479 scopus 로고
    • The effect of peripheral loading with kynurenine and probenecid on extracellular striatal kynurenic acid concentrations
    • Miller, J.M., MacGarvey, U., and Beal, M.F., 1992, The effect of peripheral loading with kynurenine and probenecid on extracellular striatal kynurenic acid concentrations. Neurosci. Lett. 146:115.
    • (1992) Neurosci. Lett. , vol.146 , pp. 115
    • Miller, J.M.1    MacGarvey, U.2    Beal, M.F.3
  • 9
    • 0026535226 scopus 로고
    • Neuroprotective effects of L-kynurenine on hypoxia-ischemia and NMDA lesions in neonatal rats
    • Nozaki, K., and Beal, M.F., 1992, Neuroprotective effects of L-kynurenine on hypoxia-ischemia and NMDA lesions in neonatal rats. J. Cereb. Blood Flow Metab. 12:400.
    • (1992) J. Cereb. Blood Flow Metab. , vol.12 , pp. 400
    • Nozaki, K.1    Beal, M.F.2
  • 10
    • 0025771636 scopus 로고
    • Measurement of rat brain kynurenine aminotransferase at physiological kynurenine concentrations
    • Okuno, E., Schmidt, W., Parks, D.A., Nakamura, M., and Schwarcz, R., 1991, Measurement of rat brain kynurenine aminotransferase at physiological kynurenine concentrations. J. Neurochem. 57:533.
    • (1991) J. Neurochem. , vol.57 , pp. 533
    • Okuno, E.1    Schmidt, W.2    Parks, D.A.3    Nakamura, M.4    Schwarcz, R.5
  • 11
    • 0019294951 scopus 로고    scopus 로고
    • Metabolism of 6-chlorotryptophan to 4-chloro-3-hydroxyanthranilic acid: A potent inhibitor of 3-hydroxyanthranilic acid oxidase
    • Parli, C.J., Krieter, P., and Schmidt, B., Metabolism of 6-chlorotryptophan to 4-chloro-3-hydroxyanthranilic acid: a potent inhibitor of 3-hydroxyanthranilic acid oxidase. Arch. Biochem. Biophys. 203:161.
    • Arch. Biochem. Biophys. , vol.203 , pp. 161
    • Parli, C.J.1    Krieter, P.2    Schmidt, B.3
  • 12
    • 0028343956 scopus 로고
    • Modulation of the kynurenine pathway in search for new neuroprotective agents. Synthesis and preliminary evaluation of (m-nitrobenzoyl)alanine, a potent inhibitor of kynurenine-3-hydroxylase
    • Pellicciari, R., Natalini, B., Costantino, G., Mahmoud, M.R., Mattioli, L., Sadeghpour, B.M., Moroni, F., Chiarugi, A., and Carpenedo, R., 1994. Modulation of the kynurenine pathway in search for new neuroprotective agents. Synthesis and preliminary evaluation of (m-nitrobenzoyl)alanine, a potent inhibitor of kynurenine-3-hydroxylase. J. Med. Chem. 37:647.
    • (1994) J. Med. Chem. , vol.37 , pp. 647
    • Pellicciari, R.1    Natalini, B.2    Costantino, G.3    Mahmoud, M.R.4    Mattioli, L.5    Sadeghpour, B.M.6    Moroni, F.7    Chiarugi, A.8    Carpenedo, R.9
  • 13
    • 0028047244 scopus 로고
    • Elevation of the neurotoxin quinolinic acid occurs following spinal cord trauma
    • Popovich, P.G., Reinhard Jr., J.F., Flanagan, E.M., and Stokes, B.T., 1994, Elevation of the neurotoxin quinolinic acid occurs following spinal cord trauma. Brain Res. 633:348.
    • (1994) Brain Res. , vol.633 , pp. 348
    • Popovich, P.G.1    Reinhard Jr., J.F.2    Flanagan, E.M.3    Stokes, B.T.4
  • 14
    • 0028691007 scopus 로고
    • Quinolinic acid in neurological disease: Opportunities for novel drug discovery
    • Reinhard Jr., J.F., Erickson, J.B., and Flanagan, E.M., 1994, Quinolinic acid in neurological disease: opportunities for novel drug discovery. Adv. Pharmacol. 30:85.
    • (1994) Adv. Pharmacol. , vol.30 , pp. 85
    • Reinhard Jr., J.F.1    Erickson, J.B.2    Flanagan, E.M.3
  • 15
    • 0027459915 scopus 로고
    • Mechanism of delayed increases in kynurenine pathway metabolism in damaged brain regions following transient cerebral ischemia
    • Saito, K., Nowak, T.S., Markey, S.P., and Heyes, M.P., 1993, Mechanism of delayed increases in kynurenine pathway metabolism in damaged brain regions following transient cerebral ischemia. J. Neurochem. 60:180.
    • (1993) J. Neurochem. , vol.60 , pp. 180
    • Saito, K.1    Nowak, T.S.2    Markey, S.P.3    Heyes, M.P.4
  • 16
    • 0025236518 scopus 로고
    • Measurement of kynurenic acid in mammalian brain extracts and cerebrospinal fluid by high-performance liquid chromatography with fluorimetric detection and coulometric electrode array detection
    • Swartz, K.J., Matson, W.R., Mac Garvey, U., Ryan, E.A., and Beal, M.F., 1990, Measurement of kynurenic acid in mammalian brain extracts and cerebrospinal fluid by high-performance liquid chromatography with fluorimetric detection and coulometric electrode array detection. Anal. Biochem. 185:363.
    • (1990) Anal. Biochem. , vol.185 , pp. 363
    • Swartz, K.J.1    Matson, W.R.2    Mac Garvey, U.3    Ryan, E.A.4    Beal, M.F.5
  • 17
    • 0001775306 scopus 로고
    • Excitotoxins, kynurenines and neuropsychiatric diseases: Implications for drug development
    • A. Schousboe, N.H. Diemer, and H. Kofod, eds., Munksgaard, Copenhagen
    • Schwarcz, R., 1992, Excitotoxins, kynurenines and neuropsychiatric diseases: implications for drug development, in: "Drug Research Related to Neuroactive Amino Acids", A. Schousboe, N.H. Diemer, and H. Kofod, eds., Munksgaard, Copenhagen.
    • (1992) Drug Research Related to Neuroactive Amino Acids
    • Schwarcz, R.1
  • 18
    • 0026707616 scopus 로고
    • Kynurenic acid: A potential pathogen in brain disorders
    • "Neurotoxins and Neurodegenerative Disease", J.W. Langston and A. Young eds., New York
    • Schwarcz, R., Du, F., Schmidt, W., Turski, W.A., Gramsbergen, J.P.B., Okuno, E., and Roberts, R.C., 1992, Kynurenic acid: a potential pathogen in brain disorders, in: "Neurotoxins and Neurodegenerative Disease", J.W. Langston and A. Young eds., Ann. N.Y. Acad. Sci. Vol. 648, New York, p. 140.
    • (1992) Ann. N.Y. Acad. Sci. , vol.648 , pp. 140
    • Schwarcz, R.1    Du, F.2    Schmidt, W.3    Turski, W.A.4    Gramsbergen, J.P.B.5    Okuno, E.6    Roberts, R.C.7
  • 19
    • 0023618280 scopus 로고
    • Increased quinolinic acid metabolism following neuronal degeneration in the rat hippocampus
    • Speciale, C., Okuno, E., and Schwarcz, R., 1987, Increased quinolinic acid metabolism following neuronal degeneration in the rat hippocampus. Brain Res. 436:18.
    • (1987) Brain Res. , vol.436 , pp. 18
    • Speciale, C.1    Okuno, E.2    Schwarcz, R.3
  • 21
    • 0024466597 scopus 로고
    • Production of extracellular quinolinic acid in the striatum: Studies by microdialysis in unanesthetized rats
    • Speciale, C., Ungerstedt, U., and Schwarz, R., 1989b, Production of extracellular quinolinic acid in the striatum: studies by microdialysis in unanesthetized rats. Neurosci. Lett. 104:345.
    • (1989) Neurosci. Lett. , vol.104 , pp. 345
    • Speciale, C.1    Ungerstedt, U.2    Schwarz, R.3
  • 22
    • 0025277138 scopus 로고
    • Determination of extracellular kynurenic acid in the striatum of unanesthetized rats: Effects of aminooxyacetic acid
    • Speciale, C., Wu, H.-Q., Gramsbergen, J.B., Turski, W.A., Ungerstedt, U., and Schwarcz, R., 1990, Determination of extracellular kynurenic acid in the striatum of unanesthetized rats: effects of aminooxyacetic acid. Neurosci. Lett. 116:198.
    • (1990) Neurosci. Lett. , vol.116 , pp. 198
    • Speciale, C.1    Wu, H.-Q.2    Gramsbergen, J.B.3    Turski, W.A.4    Ungerstedt, U.5    Schwarcz, R.6
  • 23
    • 0027486072 scopus 로고
    • Neuropharmacology of quinolinic and kynurenic acids
    • Stone, T.W., Neuropharmacology of quinolinic and kynurenic acids, 1993, Pharmacol. Rev. 45:309.
    • (1993) Pharmacol. Rev. , vol.45 , pp. 309
    • Stone, T.W.1
  • 24
    • 0027067764 scopus 로고
    • Kynurenic acid in the quinolinate-lesioned rat hippocampus: Studies in vitro and in vivo
    • Wu, H.-Q, Baran, H., Ungerstedt, U., and Schwarcz, R., 1992, Kynurenic acid in the quinolinate-lesioned rat hippocampus: studies in vitro and in vivo. Eur. J. Neurosci. 4: 1264.
    • (1992) Eur. J. Neurosci. , vol.4 , pp. 1264
    • Wu, H.-Q.1    Baran, H.2    Ungerstedt, U.3    Schwarcz, R.4
  • 25
    • 1542391750 scopus 로고
    • Seizure-related increases in extracellular kynurenic acid levels in the rat hippocampus
    • Abstr. 20
    • Wu, H.-Q., and Schwarcz, R., 1994, Seizure-related increases in extracellular kynurenic acid levels in the rat hippocampus. Soc. Neurosci., Abstr. 20, 408.
    • (1994) Soc. Neurosci. , pp. 408
    • Wu, H.-Q.1    Schwarcz, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.