-
1
-
-
0028943870
-
Design, synthesis, and structure-activity relationships of 2-substituted-2-amino-1,3-propane-diols: Discovery of a novel immunosuppressant, FTY 720
-
Adachi K, Kohara T, Nakao N, et al. Design, synthesis, and structure-activity relationships of 2-substituted-2-amino-1,3-propane-diols: discovery of a novel immunosuppressant, FTY 720. Bioorg Med Chem Lett. 5:1995;853-856.
-
(1995)
Bioorg Med Chem Lett
, vol.5
, pp. 853-856
-
-
Adachi, K.1
Kohara, T.2
Nakao, N.3
-
2
-
-
0030049234
-
A novel immunosuppressant, FTY720, with a unique mechanisms of action, induces long-term graft acceptance in rat and dog allotransplantation
-
Suzuki S, Enosawa SN, Kakefuda T, et al. A novel immunosuppressant, FTY720, with a unique mechanisms of action, induces long-term graft acceptance in rat and dog allotransplantation. Transplantation. 61:1996;200-205.
-
(1996)
Transplantation
, vol.61
, pp. 200-205
-
-
Suzuki, S.1
Enosawa, S.N.2
Kakefuda, T.3
-
3
-
-
0030248747
-
Immunosuppressive effect of a new drug, FTY720, on lymphocyte responses in vitro and cardiac allograft survival in rats
-
Suzuki S, Enosawa S, Kakefuda T, et al. Immunosuppressive effect of a new drug, FTY720, on lymphocyte responses in vitro and cardiac allograft survival in rats. Transplant Immunol. 4:1996;252-255.
-
(1996)
Transplant Immunol
, vol.4
, pp. 252-255
-
-
Suzuki, S.1
Enosawa, S.2
Kakefuda, T.3
-
4
-
-
0029996293
-
FTY720, a novel immunosuppresant possessing unique mechanisms. I. Prolongation of skin allograft survival and synergistic effect in combination with cyclosporine in rats
-
Chiba K, Hoshino Y, Suzuki C, et al. FTY720, a novel immunosuppresant possessing unique mechanisms. I. Prolongation of skin allograft survival and synergistic effect in combination with cyclosporine in rats. Transplant Proc. 28:1996;1056-1059.
-
(1996)
Transplant Proc
, vol.28
, pp. 1056-1059
-
-
Chiba, K.1
Hoshino, Y.2
Suzuki, C.3
-
5
-
-
0032525049
-
FTY720, a novel immunosupressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. I. FTY720 selectively decreases the number of circulating mature lymphocytes by acceleration of lymphocyte homing
-
Chiba K, Yanagawa Y, Masubuchi Y, et al. FTY720, a novel immunosupressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. I. FTY720 selectively decreases the number of circulating mature lymphocytes by acceleration of lymphocyte homing. J Immunol. 160:1998;5037-5044.
-
(1998)
J Immunol
, vol.160
, pp. 5037-5044
-
-
Chiba, K.1
Yanagawa, Y.2
Masubuchi, Y.3
-
6
-
-
0029918395
-
FTY720, a novel immunosuppressant possessing unique mechanisms. II. Long-term graft survival induction in rat heterotopic cardiac allografts and synergistic effect in combination with cyclosporin A
-
Hoshino Y, Suzuki C, Ohtsuki M, Masubuchi Y, Amano Y, Chiba K. FTY720, a novel immunosuppressant possessing unique mechanisms. II. Long-term graft survival induction in rat heterotopic cardiac allografts and synergistic effect in combination with cyclosporin A. Transplant Proc. 28:1996;1060-1061.
-
(1996)
Transplant Proc
, vol.28
, pp. 1060-1061
-
-
Hoshino, Y.1
Suzuki, C.2
Ohtsuki, M.3
Masubuchi, Y.4
Amano, Y.5
Chiba, K.6
-
7
-
-
0032103938
-
FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. II. FTY720 prolongs skin allograft survival by decreasing T-cell infiltration into grafts but not cytokine production in vivo
-
Yanagawa Y, Sugahara K, Kataoka H, Kawaguchi T, Masubuchi Y, Chiba K. FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. II. FTY720 prolongs skin allograft survival by decreasing T-cell infiltration into grafts but not cytokine production in vivo. J Immunol. 160:1998;5493-5499.
-
(1998)
J Immunol
, vol.160
, pp. 5493-5499
-
-
Yanagawa, Y.1
Sugahara, K.2
Kataoka, H.3
Kawaguchi, T.4
Masubuchi, Y.5
Chiba, K.6
-
8
-
-
0031829913
-
A novel immunosuppressant, FTY720, increases the efficiency of a superantigen-induced peripheral T-cell deletion whilst inhibiting negative selection in the thymus
-
Shimizu C, Li X, Kimura M, et al. A novel immunosuppressant, FTY720, increases the efficiency of a superantigen-induced peripheral T-cell deletion whilst inhibiting negative selection in the thymus. Immunology. 94:1998;503-512.
-
(1998)
Immunology
, vol.94
, pp. 503-512
-
-
Shimizu, C.1
Li, X.2
Kimura, M.3
-
9
-
-
0032522702
-
Immunosuppressive effects of FTY720 alone or in combination with cyclosporine and/or sirolimus
-
Wang ME, Tejpal N, Qu X, et al. Immunosuppressive effects of FTY720 alone or in combination with cyclosporine and/or sirolimus. Transplantation. 65:1998;899-905.
-
(1998)
Transplantation
, vol.65
, pp. 899-905
-
-
Wang, M.E.1
Tejpal, N.2
Qu, X.3
-
10
-
-
0029887890
-
FTY720, a novel immunosuppressant possessing unique mechanisms. III. Synergistic prolongation of canine renal allograft survival in combination with cyclosporin A
-
Kawaguchi T, Hoshino Y, Rahman F, et al. FTY720, a novel immunosuppressant possessing unique mechanisms. III. Synergistic prolongation of canine renal allograft survival in combination with cyclosporin A. Transplant Proc. 28:1996;1062-1063.
-
(1996)
Transplant Proc
, vol.28
, pp. 1062-1063
-
-
Kawaguchi, T.1
Hoshino, Y.2
Rahman, F.3
-
11
-
-
0032128078
-
Preclinical evaluation of a new immunosuppressive agent, FTY720
-
Troncosco P, Kahan B. Preclinical evaluation of a new immunosuppressive agent, FTY720. Clin Biochem. 31:1998;369-373.
-
(1998)
Clin Biochem
, vol.31
, pp. 369-373
-
-
Troncosco, P.1
Kahan, B.2
-
12
-
-
0031609665
-
Effect of FTY720 on immunoregulation in concordant xenotransplantation
-
Fukuda Y, Ohdan H, Miyata Y, Shintaku S, Dohi K. Effect of FTY720 on immunoregulation in concordant xenotransplantation. Transpl Int. 11:1998;S461-S464.
-
(1998)
Transpl Int
, vol.11
-
-
Fukuda, Y.1
Ohdan, H.2
Miyata, Y.3
Shintaku, S.4
Dohi, K.5
-
13
-
-
0031741847
-
FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats, III. Increase in frequency of CD62L-positive T cells in Peyer's patches by FTY720-induced lymphocyte homing
-
Yanagawa Y, Masubuchi Y, Chiba K. FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats, III. Increase in frequency of CD62L-positive T cells in Peyer's patches by FTY720-induced lymphocyte homing. Immunology. 95:1998;591-594.
-
(1998)
Immunology
, vol.95
, pp. 591-594
-
-
Yanagawa, Y.1
Masubuchi, Y.2
Chiba, K.3
-
14
-
-
85031629487
-
FTY720: A novel drug that prevents organ graft rejection by modulating T- And B-cell recirculation
-
in press.
-
Brinkmann V, Xue C, Feng L, Chiba K, Pinschewe D. FTY720: a novel drug that prevents organ graft rejection by modulating T- and B-cell recirculation. TiPS. 1999;. in press.
-
(1999)
TiPS
-
-
Brinkmann, V.1
Xue, C.2
Feng, L.3
Chiba, K.4
Pinschewe, D.5
-
15
-
-
0030245686
-
Induction of selective cell death targeting on mature T lymphocytes in rats by a novel immunosuppressant, FTY720
-
Enosawa S, Suzuki S, Kakefuda T, Li XK, Amemiya H. Induction of selective cell death targeting on mature T lymphocytes in rats by a novel immunosuppressant, FTY720. Immunopharmacology. 34:1996;171-179.
-
(1996)
Immunopharmacology
, vol.34
, pp. 171-179
-
-
Enosawa, S.1
Suzuki, S.2
Kakefuda, T.3
Li, X.K.4
Amemiya, H.5
-
16
-
-
0030794189
-
An immunosuppressive agent, FTY720, increases intracellular concentration of calcium ion and induces apoptosis in HL-60
-
Shinomiya T, Li XK, Amemiya H, Suzuki S. An immunosuppressive agent, FTY720, increases intracellular concentration of calcium ion and induces apoptosis in HL-60. Immunology. 91:1997;594-600.
-
(1997)
Immunology
, vol.91
, pp. 594-600
-
-
Shinomiya, T.1
Li, X.K.2
Amemiya, H.3
Suzuki, S.4
-
17
-
-
0020503884
-
Renal allograft survival in the baboon using a pretreatment protocol with cyclosporine
-
Smith JA, Drielsma RF, Myburgh JA, Laupacis A, Stiller CR. Renal allograft survival in the baboon using a pretreatment protocol with cyclosporine. Transplantation. 36:1983;121-124.
-
(1983)
Transplantation
, vol.36
, pp. 121-124
-
-
Smith, J.A.1
Drielsma, R.F.2
Myburgh, J.A.3
Laupacis, A.4
Stiller, C.R.5
-
18
-
-
0028069820
-
Sensitivity of baboon lymphocytes to cyclosporin A and FK 506: Relative resistance of alloactivated cells to CyA
-
Stark JH, Smith JA, Gridelli B. Sensitivity of baboon lymphocytes to cyclosporin A and FK 506: relative resistance of alloactivated cells to CyA. Transpl Int. 7:1994;372-378.
-
(1994)
Transpl Int
, vol.7
, pp. 372-378
-
-
Stark, J.H.1
Smith, J.A.2
Gridelli, B.3
-
19
-
-
0029857032
-
A new immunosuppressant, FTY720, induces bcl-2-associated apoptotic cell death in human lymphocytes
-
Suzuki S, Li XK, Enosawa S, Shinomiya T. A new immunosuppressant, FTY720, induces bcl-2-associated apoptotic cell death in human lymphocytes. Immunology. 89:1996;518-523.
-
(1996)
Immunology
, vol.89
, pp. 518-523
-
-
Suzuki, S.1
Li, X.K.2
Enosawa, S.3
Shinomiya, T.4
-
20
-
-
0031014480
-
The in vivo induction of lymphocyte apoptosis in MRL-lpr/lpr mice treated with FTY720
-
Suzuki S, Li XK, Shinomiya T, et al. The in vivo induction of lymphocyte apoptosis in MRL-lpr/lpr mice treated with FTY720. Clin Exp Immunol. 107:1997;103-111.
-
(1997)
Clin Exp Immunol
, vol.107
, pp. 103-111
-
-
Suzuki, S.1
Li, X.K.2
Shinomiya, T.3
|