Classification and grading of low-grade astrocytic tumors in children

Brain Pathology

Volumn 7, Issue 2, 1997, Pages 785-798

  Giannini, Caterina ^a   Scheithauer, Bernd W ^b  

^a OSPEDALE CA FONCELLO   (Italy)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASTROCYTOMA; BRAIN TUMOR; CANCER CLASSIFICATION; CHILD; CHILDHOOD CANCER; CONFERENCE PAPER; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY;

EID: 0030957897     PISSN: 10156305     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1750-3639.1997.tb01064.x     Document Type: Conference Paper

References (128)

1. Abdollahzadeh M, Hoffman HJ, Blazer SI, Becker LE, Humphreys RP, Drake JM, Rutka JT (1994) Benign cerebellar astrocytoma in childhood experience at the Hospital for Sick Children 1980-1992. Childs Nerv Syst 10 380-3
2. Afra D, Muller W, Slowik F, Firching R (1986) Supratentorial lobar pilocytic astrocytomas. report of 45 operated cases, including 9 recurrences. Acta Neurochir (Wien) 81: 90-93
3. Albright AL, Guthkelch AN, Packer RJ, Price RA (1986) Prognostic factors in pediatric brain-stem gliomas. J Neurosurg 65: 751-755
4. Allegranza A, Ferraresi S, Bruzzone M, Giombini S (1991) Cerebromeningeal pleomorphic xanthoastrocytoma: report on four cases - clinical, radiologic, and pathological features (including a case with malignant evolution). Neurosurg Rev 14 43-49
5. Alpers CE, Davis RL, Wilson CB (1982) Persistence and late malignant transformation of childhood cerebellar astrocytoma case report. J Neurosurg 57: 548-551
6. Altermatt HJ, Scheithauer BW (1992) Cytomorphology of subependymal giant cell astrocytoma. Acta Cytologica 36: 171-175
7. Alvord EC, Lofton S (1988) Gliomas of the optic nerve or chiasm: outcome by patient's age, tumor site, and treatment. J Neurosurg 68: 85-98
8. Anonymous (1988) A study of childhood brain tumors based on surgical biopsies from ten North American institutions: sample description: Childhood Brain Tumor Consortium. J Neuro-Oncol 6: 9-23
9. Auer RN, Riel GP, Hinton GG, Amacher AL, Gilbert JJ (1981) Cerebellar astrocytoma with benign histology but malignant clinical course. J Neurosurg 54 128-132
10. Bernell WR, Kepes JJ, Seitz EP (1972) Late malignant recurrence of childhood cerebellar astrocytoma. report of two cases. J Neurosurg 37: 470-474
11. Bernstein M, Huffman HJ, Halliday WC, Hendrick EB, Humphreys RP (1984) Thalamic tumors in children: long-term follow-up and treatment guidelines. J Neurosurg 61: 649-656
12. Bernstein M, Laperriere N (1991) Radiation injury to the nervous system In: Radiation induced tumors of The nervous system, Gutin PH, Leibel SA, Sheline GE (eds): New York. Raven Press Ltd, pp 455-472
13. Boesel CP, Paulson GW, Kosnik EJ, Earle KM (1979) Brain hamartomas and tumors associated with tuberous sclerosis. Neurosurg 4: 410-417
14. Bonnin JM, Rubinstein LJ, Papasozomenos SC, Marangos PJ (1984) Subependymal giant cell astrocytoma: Significance and possible cytogenetic implications of an immunohistochemical study. Acta Neuropathol 62: 185-193
15. Borit A, Richardson EP Jr (1982) The biological and clinical behavior of pilocytic astrocytomas of the optic pathways. Brain 105: 161-187
16. Budka H (1975) Partially resected and irradiated cerebellar astrocytoma of childhood: malignant evolution after 28 years. Acta Neurochir (Wien) 32: 139-146
17. Burger PC, Breiter SN, Fisher PG (1996) Pilocytic and fibrillary astrocytomas of the brain stem - a comparative clinical, radiological, and pathological study J Neuropath Exp Neurol 55: 640
18. Burger PC, Scheithauer BW, Vogel FS (1991) Surgical Pathology of the Nervous System and Its Coverings, 3rd Edition, Churchill Livingstone
19. Burger PC, Scheithauer BW (1994) Tumors of the Central Nervous System, Atlas of Tumor Pathology, Third Series, Fascicle 10, Armed Forces Institute of Pathology, Washington D C.
20. Casadei GP, Arrigoni GL, D'Angelo V, Bizzozero L (1990) Late malignant recurrence of childhood cerebellar astrocytoma Clin Neuropathol 9: 295-298
21. Chow CW, Klug GL, Lewis EA (1988) Subependymal giant cell astrocytoma in children: an unusual discrepancy between histological and clincial features. J Neursurg 68: 880-883
22. Coakley KJ, Huston J III, Scheithauer BW, Forbes GS, Kelly PJ (1995) Pilocytic Astrocytomas: Well-Demarcated Magnetic Resonance Appearance Despite Infrequent Infiltration Histologically Mayo Clin Proc 70: 747-751
23. Cohen MS, Kushner MJ, Dell S (1981) Frontal lobe astrocytoma following radiotherapy for medulloblastoma. Neurology 31: 616-619
24. Connor JM, Stephenson JPB, Hadley MDM (1986) Non-penetrance in tuberous sclerosis. Lancet 2: 1275 (letter)
25. Costantini S, Houten J, Miller DC, Freed D, Ozek MM, Rorke LB, Allen JC, Epstein FJ (1996) Intramedullary spinal cord tumors in children under the age of 3 years. J Neurosurg 85: 1036-1043
26. Gushing H (1931) Experiences with the cerebellar astrocytomas. A critical review of seventy-six cases. Surg Gyne Obstet 52: 129-191
27. Daumas-Duport C, Scheithauer BW, O'Fallon J, Kelly P (1988) Grading of astrocytomas. A simple and reproducible method Cancer 62: 2152-2165
28. Dropcho EJ, Wisoff JH, Walker RW, Allen JC (1987) Supratentorial malignant gliomas in childhood a review of fifty cases. Ann Neurol 22: 355-364
29. Dirks PB, Jay V, Becker LE, Drake JM, Humphreys RP, Hoffman HJ, Rutka JT (1994) Development of anaplastic changes in low-grade astrocytomas of childhood, Neurosurg 34: 68-78
30. Flickinger JC, Torres C, Deutsch M (1988) Management of low-grade gliomas of the optic nerve and chiasm. Cancer 61: 635-642
31. Forsyth PA, Shaw EG, Scheithauer BW, O'Fallon JR, Layton DD Katzmann JA (1993) Supratentorial pilocytic astrocytomas. Cancer 72 1335-1342
32. Furuta A, Takahasi H, Fusahiro I, Onda K, Takeda N, Tanaka R (1992) Temporal lobe tumor demonstrating ganglioglioma and pleomorphic xanthoastrocytoma components J Neurosurg 77: 143-147
33. Garcia DM, Latifi HR, Simpson JR, Picker S (1989) Astrocytomas of the cerebellum in the children. J Neurosurg 71 661-664
34. Gaskill SJ, Marlin AE, Saldivar V (1988) Glioblastoma multiforme masquerading as a pleomorphic xanthoastrocytoma Childs Nerv Syst 4 237-240
35. Giannini C, Scheithauer BW, Burger PC, Christensen MR, Wollan PC, Sebo TJ, Forsyth PA, Hayostek CJ (1996) The MIB-1 LI in pilocytic and diffuse astrocytomas. J Neuropathol Exp Neurol 55: 605
36. Gilles FH, Leviton A, Hedley-White ET, Sobel E, Tavare CJ, Sobel RS and Rorke LB (1992) Childhood brain tumors that occupy more than one compartment at presentation J Neurooncol 14: 45-56
37. Gjerris F, Klinken L (1978) Long-term prognosis in children with benign cerebellar astrocytoma. J Neurosurg 49: 179-184
38. Gomez JG, Garcia JH, Colon LE (1985) A variant of cerebral gtioma called pleomorphic xanthoastrocytoma: Case report Neurosurg 16: 703-706
39. Gomez MR (1988) Varieties of expression of tuberous sclerosis. Neurofibromatosis 1: 330-338
40. Grant JW, Gallagher PJ (1986) Pleomorphic xanthoastrocytoma: immunohistochemical methods for differentiation from fibrous histiocytomas with similar morphology. Am J Surg Pathol 10: 336-341
41. Griffen TW, Beaufait D, Blasko JC (1979) Cystic cerebellar astrocytomas in children. Cancer 44: 276-280
42. Halmagyi GM, Bignold LR Allsop JL (1979) Recurrent subependymal giant cell astrocytoma in the absence of tuberous sclerosis: Case report. J Neurosurg 50: 106-109
43. Hayostek CJ, Shaw EG, Scherthauer BW, O'Fallon JR, Weiland TL, Schomberg PJ, Ketly PJ, Hu TC (1993) Astrocytomas of the cerebellum A comparative clinico-pathological study of pilocytic and diffuse astrocytomas. Cancer 72: 856-869
44. Hirose T, Scheithauer BW, Lopes MBS, Gerber HA, Altermatt HJ, Hukee MJ, Vandenberg SR, Charlesworth JC (1995) Tuber and subependymal giant cell astrocytoma associated withtuberous sclerosis an immunohistochemical, ultrastructural, and immunoelectron microscopic study. Acta Neuropath 90: 387-399
45. Hirsch JR, Sainte Rose C, Pierre-Kahn A, Pfister A, Hoppe-Hirsch E (1985) Benign astrocytic and oligodendrocytic tumors of the cerebral hemispheres in children. J Neurosurg 62: 811-815
46. Huffman HJ, Humphreys RP, Drake JM, Rutka JT, Backer LE, Jenkin D, Greenberg M (1993) Optic pathway/hypothalamic gliomas: a dilemma in management Pediatr Neurosurg 19: 186-95
47. Huffman HJ, Soloniuk DS, Humphreys RP, Drake JM, Becker LE, De Lima BO, Piatt JH Jr (1993) Management and outcome of low-grade astrocytomas of the midline in children a retrospective review. Neurosurg 33: 964-971
48. Hosokawa Y, Tsuchihashi Y, Okabe H, Toyama M, Namura K, Kuga M, Yonezawa T, Fujita S, Ashihara T (1991) Pleomorphic xanthoastrocytoma: ultrastructural, immunohistochemical, and DNA cytofluorometric study of a case. Cancer 68: 853-859
49. Hoyt WF, Meshel LG, Lessell S, Schatz NJ, Suckling RD (1973) Malignant optic glioma of adulthood. Brain 96: 121-123
50. Iwaki T, Fukui M, Kondo A, Matsushima T, Takeshita I (1987) Epithelial properties of pleomorphic xanthoastrocytomas determined in ultrastructural and immunohistochemical studies. Acta Neuropathol (Berl) 74: 142-150
51. Jervis GA (1954) Spongioneuroblastoma and tuberous sclerosis. J Neuropath Exp Neurol 13: 105-116
52. Jones JC, Drut R, Gaglia G (1983) Pleomorphic xanthoastrocytoma: a report of two cases. Pediatr Pathol 1: 459-467
53. Kanamon M, Shibuya M, Takayasu M, Kageyama N (1985) Long-term followup of patients with optic glioma. Child's Nerv Syst 1: 272-278
54. Kepes JJ, Kepes M, Slowik F (1973) Fibrous xanthomas and xanthosarcomas of the meninges and the brain. Acta Neuropathol 23: 187-199
55. Kepes JJ, Rubinstein LJ, Eng LF (1979) Pleomorphic xanthoastrocytoma: a distinctive meningocerebral glioma of young subjects with relatively favorable prognosis-a study of 12 cases. Cancer 44: 1839-1852
56. Kepes JJ, Lewis RC, Vergara GG (1980) Cerebellar astrocytoma invading the musculature and soft tissues of the neck, case report J Neurosurg 52: 414-418
57. Kepes JJ, Rubinstein LJ, Ansbacher L, Schreiber DJ (1989) Histopathological features of recurrent pleomorphic xanthoastrocytomas further corroboration of the glial nature of this neoplasm. A study of three cases. Acts Neuropathol 78: 585-593
58. Khatib Z, Herdemann R, Kovnar E, Sanford R, Fairclough D, Langsten J, Douglas E, Ochs J, Jenkins J, Ogle L, Kun L (1992) Pilocytic dorsally exophytic brainstem gliomas: a distinct clinicopathologic entity. Ann Neurol 32: 458-459
59. Kim TS, Halliday AL, Hedley-Whyte ET, Convery K (1991) Correlates of survival and the Daumas-Duport grading system for astrocytomas. J Neurosurg 74: 27-37
60. Kingsley DPE, Kendall BE, Fitz CR (1986) Tuberous sclerosis, a clinicoradiological evaluation of 110 cases with particular reference to atypical presentation. Neuroradiology 28: 38-46
61. Kleihues P, Burger PC, Scheithauer BW (1993) Histological Typing of Tumors of the Central Nervous System, 2nd Edition, World Health Organization, Springer-Verlag, Berlin
62. Kleinman GM, Schoene WC, Walshe TM III, Richardson EP Jr (1978) Malignant transformation in benign cerebellar astrocytoma: case report. J Neurosurg 49: 111-118
63. Kleriga E, Sher JH, Nallainathan SK, Stein SC, Sacher M (1978) Development of cerebellar malignant astrocytoma at site of a medulloblastoma treated 11 years earlier. Case report. J Neurosurg 49: 445-449
64. Kros JM, Vecht CJ, Stefanko SZ (1991) The pleomorphic xanthoastrocytoma and its differential diagnosis: a study of five cases. Hum Pathol 22: 1128-1135
65. Kuhajda FP, Mendelsohn G, Taxy JS, Long DM (1981) Pleomorphic xanthoastrocytoma. report of a case with light and electron microscopy. Ultra structural Pathol 2: 25-32
66. Laws ER Jr, Taylor WF, Clifton MB, Okazaki H (1984) Neurosurgical management of low-grade astrocytoma of the cerebral hemispheres. J Neurosurg 61: 655-673
67. Lipper MH, Eberhard DA, Phillips CD, Vezina L-G, Cail WS (1993) Pleomorphic xanthoastrocytoma, a distinctive astroglial tumor: Neuroradiologic and pathologic features. Am J Neurol 14: 1397-1404
68. Lopes MBS, Altermatt HJ, Scheithauer BW, Shepherd CW, Vandenberg SR (1996) Immunohistochemical characterization of subependymal giant cell astrocytoma Acta Neuropath 91: 368-375
69. Maat-Schieman MLC, Bots GTAM, Thomeer RTWM, Vielvoye GJ (1985) Malignant astrocytoma following radiotherapy for craniopharyngioma. Br J Radiol 58: 480-482
70. Macaulay RJ, Jay V, Hoffman HJ, Becker LE (1993) Increased mitotic activity as a negative prognostic indicator in pleomorphic xanthoastrocytoma. J Neurosurg 79: 761-767
71. Malecki M, Robitaille Y, Bertrand G (1983) Atypical xanthoastrocytoma presenting as a meningioma Surg Neurol 20: 235-238
72. Marus G, Levin CV, Rutherfoord GS (1986) Malignant glioma following radiotherapy for unrelated primary tumors. Cancer 58 886-894
73. MacCarty WC Jr, Russell DG (1958) Tuberous sclerosis: report of a case with ependymoma. Radiol 71: 833-838
74. Mercuri S, Russo A, Palma L (1981) Hemispheric supratentorial astrocytomas of children: long-term results in 29 cases J Neurosurg 55: 170-173
75. Miller NR, IIiff WJ, Green WR (1974) Evaluation and management of gliomas of the anterior visual pathways. Brain 97: 743-754
76. Minehan KJ, Shaw EG, Scheithauer BW, Davis DL, Onofrio BM (1995) Spinal cord astrocytoma: pathological and treatment considerations. J Neurosurg 83: 590-595
77. Morota N, Sakamoto K, Kobayashi N, Hasmimoto K (1990) Recurrent low-grade glioma in children with special reference to computerized tomography and pathological changes. Childs Nerv Syst 6: 155-160
78. Munoz EL, Eberhard DA, Lopes MBS, Schneidet BF, Gonzalez-Fernandez F, Vandenberg SR (1996) Proliferative activity and p53 mutation as prognostic indicators in pleomorphic xanthoastrocytoma A clinicopathological study of six cases J Neuropath Exp Neurol 55: 606
79. Nishio S, Takeshita I, Fukui M, Yamashita M, Tateishi J (1988) Anaplastic evolution of childhood optico-chiasmatic pilocytic astrocytoma: report of an autopsy case Clin Neuropathol 7: 254-258
80. Noetzli M, Malamud N (1962) Postirradiation fibrosarcoma of the brain. Cancer 15: 617-622
81. O'Sullivan C, Jenkin D, Doherty MA, Huffman HJ, Greenberg ML (1994) Spinal cord tumors in children: long-term results of combined surgical and radiation treatment. J Neurosurg 81: 507-512
82. Özek MM, Sav A, Pamir MN, Özer AF, Özek E, Erzen C (1993) Pleomorphic xanthoastrocytoma associated with von Recklinghausen neurofibromatosis. Childs Nerv Syst 9: 39-42
83. Packer RJ, Savino PJ, Bilaniuk LT, Zimmerman RA, Schatz NJ, Rosenstock JG, Nelson DS, Jarrett PD, Bruce DA, Schut L (1983) Chiasmatic ghomas of childhood. A reappraisal of natural history and effectiveness of cranial irradiation Child's Brain 10: 393-403
84. Pahapill PA, Ramsay DA, Phil D, Del Maestro RF (1996) Pleomorphic xanthoastrocytoma: case report and analysis of the literature concerning the efficacy of resection and the significance of necrosis. Neurosurg 38: 822-829
85. Palma L, Guidetti B (1985) Cystic pilocytic tumors of the cerebral hemispheres. Surgical experience with 51 cases and long-term results. J Neurosurg 62: 811-815
86. Palma L, Russo A, Celli P (1984) Prognosis of the so-called "diffuse" cerebellar astrocytoma Neurosurg 15: 315-317
87. Palma L, Vagnozzi R, Annino L, Ciapetta P, Maleci A, Cantore G (1988) Post-irradiation glioma in a child: case report and review of the literature Childs Nerv Syst 4: 296-301.
88. Pasquier B, Kojder I, Labat F, Keddari E, Pasquier D, Stoebner P, Barge M, Delpech B, Couderc P (1985) Le xanthoastrocytome du suject jeune: revue de la litterature à propos de deux observations dévolution discordante. Ann Pathol 5: 29-43
89. Paulus W, Pfeiffer J (1988) Does the pleomorphic xanthoastrocytorna exist? Problems in the application of immunological techniques to the classificatino of brain tumors. Acta Neuropathol 76: 245-252
90. Pearl GS, Mirra SS, Miles ML (1980) Glioblastoma multiforme occurring 13 years after treatment of a medulloblastoma. Neurosurg 6: 546-551
91. Piepmeier J, Christopher S, Spencer D, Byrne T, Kim J, Knisel JP, Lacy J, Tsukerman L, Makuch R (1996) Variations in the natural history and survival of patients with supratentorial low-grade astrocytomas Neurosurg 38 872-879
92. Pollack IF, Claassen D, Al-Shboul Q, Janosky JE, Deutsch M (1995) Low-grade gliomas of the cerebral hemi- spheres in children: an analysis of 71 cases. J Neurosurg 82: 536-547
93. Powell SZ, Yachnis AT, Rorke LB, Rojiani AM, Eskin TA (1996) Divergent differentiation in pleomorphic xanthoastrocytoma: evidence for a neuronal element and possible relationship to ganglion cell tumors. Am J Surg Pathol 20- 80-85
94. Preissig SH, Bohmfalk GL, Reichel GW, Smith MT (1979) Anaplastic astrocytoma following radiation for a glomus jugulare tumor Cancer 43: 2243-2247
95. Puech P, Lereboullet J, Bernard P (1945) Sclerose tubereuse et tumeurs cerebrales. Rev Neurolo 77: 225-246
96. Raffel C, Edwards MSB, Davis RL, Ablin AR (1985) Postirradiation cerebellar glioma. Case report. J Neurosurg 62 300-303
97. Revesz T, Scaravilli F, Couthino L, Cockburn H, Sacares P., Thomas DGT (1993) Reliability of histological diagnosis including grading in gliomas biopsied by image-guided stereotactic technique. Brain 116: 781-793.
98. Rossitch E Jr, Zeidman SM, Burger PC, Cumes JT, Harsh C, Anscher M, Oakes WJ (1990) Clinical and pathologic analysis of spinal cord astrocytomas in children. Neurosurg 27: 193-196
99. Rush JA, Young BR, Campbell RJ, MacCarthy CS (1982) Optic glioma Ophthalmology 89:1213-19
100. Sawyer JR, Roloson GJ, Chadduck WM, Boop FA (1991) Cytogenetic findings in a pleomorphic xanthoastrocytoma. Cancer Genet Cyrogenet 55: 225-230
101. Schmidbauer M, Budka H, Bruckner R, Vokapic P (1987) Glioblastoma developing at the site of a cerebellar medultoblastoma treated 6 years earlier: case report. J Neurosurg 67: 915-918
102. Schneider JH, Raffel C, McComb JG (1992) Benign cerebellar astrocytomas of childhood Neurosurg 30: 58-63
103. Schwartz AM, Ghatak NR (1990) Malignant transformation of benign cerebellar astrocytoma Cancer 65: 333-336
104. Scott RM, Ballantine HT Jr (1973) Cerebellar astrocytoma malignant recurrence after prolonged postoperative survival Case report. J Neurosurg 39: 777-779
105. Shapiro K, Katz M (1983) The recurrent cerebellar astrocytoma Childs Brain 10: 168-176
106. Shapiro K, Shulman K (1976) Spinal cord seeding from cerebellar astrocytomas. Childs Brain 2: 177-186
107. Shepherd CW, Scheithauer BW, Gomez MR, Altermatt HJ, Katzmann JA (1991) Subependymal giant cell astrocytoma a clinical,pathological and flow cytometry study Neurosurg 28 864-868
108. Spallone A, Gagliardi FM, Vagnozzi R (1979) Intracranial meningiomas related to external cranial irradiation. Surg Neurol 12 153-159
109. Spoor TC, Kennerdell JS, Martinez AJ, Zorub D (1980) Malignant gliomas of the optic pathways Am J Ophthalmol 89: 284-292
110. Steinberg GK, Shuer LM, Conley FK, Hanbery JW (1985) Evolution and outcome in malignant astroglial neoplasms of the cerebellum, J Neurosurg 62: 9-17
111. Strom EH, Skullerud K (1983) Pleomorphic xanthoastrocytoma Report of 5 cases Clin Neuropathol 2 188-191
112. Stuart G, Appleton DB, Cooke R (1988) Pleomorphic xanthoastrocytoma report of two cases. Neurosurg 22: 422-427
113. Jenny RT, Laws ER, Young BR, Rush JA (1982) The neurosurgical management of optic gliomas: results in 104 patients. J Neurosurg 57: 452-458
114. Thomas C, Golden B (1993) Pleomorphic xanthoastrocytoma: report of two cases and a brief review of the literature. Clinical Neuropathol 12 97-101
115. Tomlinson FH, Scheithauer BW, Hayostek CJ, Parisi JE, Meyer FB, Shaw EG, Weiland TL, Katzmann JA, Jack CR, Jr (1994) The significance of atypia and histological malignancy in pilocytic astrocytoma of the cerebellum: a clinicopathologic and flow cytometric study. J Child Neurol 9: 301-310
116. Tsuchida T, Kamata K, Kawamata M, Okada K, Tanaka R, Oyake Y (1981) Brain Tumors in tuberous sclerosis: report of 4 cases. Childs Brain 7: 271-283
117. Ushio Y, Arita N, Yoshimine T, Ikeda T, Mogami H (1987) Malignant recurrence of childhood cerebellar astrocytoma: case report. Neurosurg 21: 251-255
118. Vandertop WP, Hoffman HJ, Drake JM, Humphreys RP, Rutka JT, Amstrong DC, Becker LE (1992) Focal midbrain tumors in children. Neurosurg 31: 186-194
119. Waga S, Manda H (1976) Radiation induced meningioma: with review of the literature. Surg Neurol 2: 161-164
120. Wallner KE, Gonzales MF, Edwards MSB, Wara WM, Sheline G (1988) Treatment results of juvenile pilocytic astrocytoma. J Neurosurg 69: 171-176
121. Whittle IR, Gordon A, Misra BK, Shaw JF, Steers JW (1989) Pleomorphic xanthoastrocytoma: report of four cases. J Neurosurg 70: 463-468
122. Wilson WB, Femsod M, Hoyt WF, Nielsen SL (1976) Malignant evolution of childhood chiasmal pilocytic astrocytoma. Neurology 26: 322-325
123. Wisoff HS, Llena JF (1989) Glioblastoma multiforme of the cerebellum five decades after irradiation of a cerebellar tumor. J Neuro-oncol 7: 339-344
124. Wisoff JH, Abbott R, Epstein F (1990) Surgical management of exophytic chiasmatic-hypothalamic tumors of childhood. J Neurosurg 73: 661-667
125. Wong JYC, Uhl V, Wara WM, Sheline GE (1987) Optic gliomas. A reanalysis of the University of California San Francisco experience. Cancer 60: 1847-1855
126. Yoshino MT, Lucio R (1992) Pleomorphic xanthoastrocytoma Am J Neuroradiol 13: 1330-1332
127. Zorzi F, Facchetti F, Baronchelli C, Cani E (1992) Pleomorphic xanthoastrocytoma: an immunohistochemical study of three cases. Histopathology 20: 267-269
128. Zulch KJ (1979) Histological typing of tumors of the central nervous system. Geneva, World Health Organization