Excessive release of [3H]noradrenaline and glutamate in response to simulation of ischemic conditions in rat spinal cord slice preparation: effect of NMDA and AMPA receptor antagonists

European Journal of Pharmacology

Volumn 366, Issue 2-3, 1999, Pages 143-150

  Nakai, Tetsui ^a,b   Milusheva, Elisaveta ^a,c   Baranyi, Maria ^a   Uchihashi, Yashitaka ^b   Satoh, Tetsuo ^b   Vizi, E Sylvester ^a  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^b NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

^c INSTITUTE OF PHYSIOLOGY   (Bulgaria)

Author keywords

Carrier mediated release; Dizocilpine; Ischemia; LY300168 (GYKI 53655); LY303070 (GYKI 53784); NMDA receptor; Non NMDA receptor; Noradrenaline release; Spinal cord

Indexed keywords

1 (4 AMINOPHENYL) 3,4 DIHYDRO 4 METHYL 3 METHYLCARBAMOYL 7,8 METHYLENEDIOXY 5H 2,3 BENZODIAZEPINE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; DIZOCILPINE; GLUTAMATE RECEPTOR ANTAGONIST; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NORADRENALIN; UNCLASSIFIED DRUG; AMINO ACID RECEPTOR BLOCKING AGENT; BENZODIAZEPINE DERIVATIVE; DIAGNOSTIC AGENT; DIZOCILPINE MALEATE; GLUCOSE; TRITIUM;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTROSTIMULATION; HYPOXIA; NERVE CONDUCTION; NONHUMAN; NORADRENALIN RELEASE; PRIORITY JOURNAL; RAT; SPINAL CORD ISCHEMIA; ANIMAL; ANOXIA; CHEMISTRY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; IN VITRO STUDY; ISCHEMIA; MALE; METABOLISM; PATHOPHYSIOLOGY; SECRETION; SPINAL CORD; STEREOISOMERISM; VASCULARIZATION; WISTAR RAT;

ANIMALS; ANOXIA; BENZODIAZEPINES; DIZOCILPINE MALEATE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; EXCITATORY AMINO ACID ANTAGONISTS; GLUCOSE; GLUTAMIC ACID; ISCHEMIA; MALE; NOREPINEPHRINE; RATS; RATS, WISTAR; RECEPTORS, AMPA; RECEPTORS, N-METHYL-D-ASPARTATE; SPINAL CORD; STEREOISOMERISM; TRITIUM;

EID: 0032587033     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(98)00917-0     Document Type: Article

References (61)

1. 2+independent release of neurotransmitters. J. Neurochem. 58:1992;395-405.
2. Adamson P., Hajimohammadreza I., Brammer M.J., Campbell I.C., Meldrum B.S. Presynaptic glutamate/quisqualate receptors: effects on synaptosomal free calcium concentrations. J. Neurochem. 55:1990;1850-1854.
3. 2B/2C-Adrenoceptor subtype antagonists prevent lipopolysaccharide-induced fever response in rabbits. Brain Res. 705:1995;302-306.
4. Breckwoldt W.L., Genco C.M., Connolly R.J., Cleveland R.J., Diehl J.T. Spinal cord protection during aortic occlusion: efficacy of intrathecal tetracaine. Ann. Thorac. Surg. 51:1991;959-963.
5. Connick J.H., Stone T.W. Excitatory amino acid antagonists and endogenous aspartate and glutamate release from rat hippocampal slices. Br. J. Pharmacol. 93:1988;863-867.
6. Davies S.N., Lodge D. Evidence for involvement of N-methylaspartate receptors in 'wind-up' of class 2 neurones in the dorsal horn of the rat. Brain Res. 424:1987;402-406.
7. Dickenson A.H., Chapman V., Green G.M. The pharmacology of excitatory and inhibitory amino acid-mediated events in the transmission and modulation of pain in the spinal cord. Gen. Pharmacol. 28:1997;633-638.
8. Doolette D.J. Mechanism of adenosine accumulation in the hippocampal slice during energy deprivation. Neurochem. Int. 30:1997;211-223.
9. Faden A.I., Demediuk P., Panter S.S., Vink R. The role of excitatory amino acids and NMDA receptors in traumatic brain injury. Science. 244:1989;798-800.
10. Figiel I., Kaczmarek L. Cellular and molecular correlates of glutamate-evoked neuronal programmed cell death in the in vitro cultures of rat hippocampal dentate gyrus. Neurochem. Int. 31:1997;229-240.
11. Ghribi O., Callebert J., Verrecchia C., Plotkine M., Boulu R.G. Blockers of NMDA-operated channels decrease glutamate and aspartate extracellular accumulation in striatum during forebrain ischemia in rats. Fundam. Clin. Pharmacol. 9:1995;141-146.
12. Globus M.Y.-T., Busto R., Dietrich W.D., Martinez E., Valdés I., Ginsberg M.D. Effect of ischemia on the in vivo release of striatal dopamine, glutamate, and γ-aminobutyric acid studied by intracerebral microdialysis. J. Neurochem. 51:1988;1455-1464.
13. Globus M.Y.-T., Busto R., Dietrich W.D., Martinez E., Valdés I., Ginsberg M.D. Direct evidence for acute and massive norepinephrine release in the hippocampus during transient ischemia. J. Cereb. Blood. Flow. Metab. 9:1989;892-896.
14. Green E.J., Pazos A.J., Dietrich W.D., McCabe P.M., Schneiderman N., Lin B., Busto R., Globus M.Y., Ginsberg M.D. Combined postischemic hypothermia and delayed MK-801 treatment attenuates neurobehavioral deficits associated with transient global ischemia in rats. Brain Res. 702:1995;145-152.
15. Green S.L., Kulp K.S., Vulliet R. Cyclic-dependent protein kinase 5 activity increases in rat brain following ischemia. Neurochem. Int. 31:1997;617-623.
16. 2-Adrenoceptor agonist, dexmedetomidine, protects against kainic acid-induced convulsions and neuronal damage. Brain Res. 693:1995;217-224.
17. 2-adrenoreceptors on plasma levels of tumour necrosis factor-α, interleukin-6 and corticosterone induced by bacterial lipopolysaccharide in mice. J. Endocrinol. 144:1995;457-462.
18. Haskó G., Németh Z.H., Szabó Cs., Zsilla G., Salzman A.L., Vizi E.S. Isoproterenol inhibits IL-10, TNF-α, and nitric-oxide production in RAW 264.7 macrophages. Brain Res. 45:1998;183-187.
19. Ikeda M., Nakazawa T., Abe K., Kaneko T., Yamatsu K. Extracellular accumulation of glutamate in the hippocampus induced by ischemia is not calcium dependent - in vitro and in vivo evidence. Neurosci. Lett. 96:1989;202-206.
20. 2-adrenoceptors inhibit glutamate release from rat spinal cord synaptosomes. J. Neurochem. 60:1993;522-526.
21. Katoh H., Sima K., Nawashiro H., Wada K., Chigasaki H. The effect of MK-801 on extracellular neuroactive amino acids in hippocampus after closed head injury followed by hypoxia in rats. Brain Res. 758:1997;153-162.
22. 2+ concentration in isolated nerve terminals following metabolic inhibition: possible relevance to hypoglycaemia and anoxia. Neuroscience. 27:1988;175-182.
23. Kimura M., Sawada K., Miyagawa T., Kuwada M., Katayama K., Nishizawa Y. Role of glutamate receptors and voltage-dependent calcium and sodium channels in the extracellular glutamate/aspartate accumulation and subsequent neuronal injury induced by oxygen/glucose deprivation in cultured hippocampal neurons. J. Pharmacol. Exp. Ther. 285:1998;178-185.
24. 3H] noradrenaline release in adult rat spinal cord Eur. J. Pharmacol. 308:1996;135-144.
25. Ko M.L., King M.A., Gordon T.L., Crisp T. The effects of aging in spinal neurochemistry in the rat. Brain Res. Bull. 42:1997;95-98.
26. Koh J.Y., Choi D.W. Selective blockade of non-NMDA receptors does not block rapidly triggered glutamate-induced neuronal death. Brain Res. 548:1991;318-321.
27. Liu H., Wang H., Sheng M., Jan L.Y., Jan Y.N., Basbaum A.I. Evidence for presynaptic N-methyl-D-aspartate autoreceptors in the spinal cord dorsal horn. Proc. Natl. Acad. Sci. USA. 91:1994;8383-8387.
28. Lobner D., Lipton P. Sigma-ligands and non-competitive NMDA antagonists inhibit glutamate release during cerebral ischemia. Neurosci. Lett. 117:1990;169-174.
29. Lodge D., Bond A., O'Neill M.J., Hicks C.A., Jones M.G. Stereoselective effects of 2.3-benzodiazepines in vitro: electrophysiology and neuroprotection studies. Neuropharmacology. 35:1996;1681-1688.
30. LoPachin R.M., Lehning E.J. Mechanism of calcium entry during axon injury and degeneration. Toxicol. Appl. Pharmacol. 143:1997;233-244.
31. Mally J., Baranyi M., Vizi E.S. Change in the concentrations of amino acids in CSF and serum of patients with essential tremor. J. Neural Transm. Gen. Sect. 103:1996;555-5560.
32. Martin D., Bustos G.A., Bowe M.A., Bray S.D., Nadler J.V. Autoreceptor regulation of glutamate and aspartate release from slices of the hippocampal CA1 area. J. Neurochem. 56:1991;1647-1655.
33. Martin R.L., Lloyd H.G.E., Cowan A.I. The early events of oxygen and glucose deprivation: setting the scene of neuronal death. Trends Neurosci. 17:1994;251-257.
34. Martin L.J., Al-Abdulla N.A., Brambrink A.M., Kirsch J.R., Sieber F.E. Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: a perspective on the contributions of apoptosis and necrosis. Brain Res. Bull. 46:1998;281-309.
35. Matsuoka Y., Kitamura Y., Fukunaga R., Shimohama S., Nabeshima T., Tooyama I., Kimura H., Tanaguchi T. In vivo hypoxia-induced neuronal damage in dentate gyrus of rat hippocampus: changes in NMDA receptors and the effect of MK-801. Neurochem. Int. 30:1997;533-542.
36. Mike A., Dyatlov V.A., Vizi E.S. Non-NMDA receptor-mediated modulation of voltage-activated outward currents in chick neurones. NeuroReport. 7:1996;2613-2617.
37. 3H] dopamine in rat striatal slices Neurochem. Int. 28:1996;501-507.
38. Newell D.W., Barth A., Papermaster V., Malouf A.T. Glutamate and non-glutamate receptor mediated toxicity caused by oxygen and glucose deprivation in organotypic hippocampal cultures. J. Neurosci. 15:1995;7702-7711.
39. + channels by antidepressant drugs. J. Pharmacol. Exp. Ther. 284:1998;208-214.
40. Pubill D., Canudas A.M., Gasulla D., Pallas M., Escubedo E., Camarasa J. MK-801 enhances noradrenergic neurotransmission in rat vas deferens. Eur. J. Pharmacol. 303:1996;171-175.
41. Rokkas C.K., Cronin C.S., Nitta T., Helfrich L.R. Jr., Lobner D.C., Choi D.W., Kouchoukos N.T. Profound systemic hypothermia inhibits the release of neurotransmitter amino acids in spinal cord ischemia. J. Thorac. Cardiovasc. Surg. 110:1995;27-35.
42. Ross M.E. Cell division and the nervous system: regulating the cycle from neural differentiation to death. Trends Neurosci. 19:1996;62-68.
43. Siesjö B.K. Cell damage in the brain: a speculative hypothesis. J. Cereb. Blood. Flow. Metab. 1:1988;155-185.
44. 2-autoreceptor and presynaptic inhibitory heteroreceptors on noradrenergic neurones. Brain Res. Bull. 47:1998;129-132.
45. Snell L.D., Yi S.J., Johnson K.M. Comparison of the effects of MK-801 and phencyclidine on catecholamine uptake and NMDA-induced norepinephrine release. Eur. J. Pharmacol. 145:1988;223-226.
46. + channel block prevents the ischemia-induced release of norepinephrine from spinal cord slices. Eur. J. Pharmacol. 346:1998;145-150.
47. 3H] noradrenaline from rat spinal cord Brain Res. Bull. 42:1997;129-132.
48. 2+) activated ATPase, of acetylcholine release in cortical slices from rat brain. J. Physiol. (London). 226:1972;95-117.
49. + activated adenosinetriphosphatase as a trigger in transmitter release. Neuroscience. 3:1978;367-384.
50. Vizi E.S. Different temperature dependence of carrier-mediated (cytoplasmic) and stimulus-evoked (exocytotic) release of transmitter: a simple method to separate the two types of release. Neurochem. Int. 33:1998;359-366.
51. Vizi E.S., Harsing L.G. Jr., Zimanvi I., Gaal G. Release and turnover of noradrenaline in isolated median eminence: lack of negative feedback modulation. Neuroscience. 16:1985;907-916.
52. Vizi E.S., Mike A., Tarnawa I. 3-Benzodiazepines (GYKI-52466 and analogs): negative allosteric modulators of AMPA receptors. CNS Drug. Rev. 2:1996;91-126.
53. Vizi E.S., Mike A., Tarnawa I. The functional study of kainate receptors - hopes and doubts. Trends Neurosci. 20:1997;396.
54. Vizi E.S., Kiss J. Neurochemistry and pharmacology of the major hippocampal transmitter systems: synaptic and non-synaptic interactions. Hippocampus. 10:1998;1-41.
55. Wieloch T., Engelsen B., Westerberg E., Auer R. Lesions of the glutamatergic cortico-striatal projections in the rat ameliorate hypoglycemic brain damage in the striatum. Neurosci. Lett. 58:1985;25-30.
56. Wohlberg C.J., Hackman J.C., Davidoff R.A. Epinephrine and norepinephrine modulate neuronal responses to excitatory amino acids and agonists in frog spinal cord. Synapse. 1:1987;202-207.
57. Wrathall J.R., Bouzoukis J., Choiniere D. Effect of kynurenate on functional deficits resulting from traumatic spinal cord injury. Eur. J. Pharmacol. 218:1992;2732-2781.
58. Wrathall J.R., Choiniere D., Teng Y.D. Dose-dependent reduction of tissue loss and functional impairment after spinal cord trauma with the AMPA/kainate antagonist NBQX. J. Neurosci. 14:1994;6598-6607.
59. Zelles T., Chernaeva L., Baranyi M., Deri Z., Adam-Vizi V., Vizi E.S. Transmitter release by non-receptor activation of the α-subunit of guanine nucleotide regulatory protein in rat striatal slices. J. Neurosci. Res. 42:1995;242-251.
60. Zhang C., Yang S.-W., Guo Y-G., Qiao J-T., Dafny N. Locus coeruleus stimulation modulates the nociceptive response in parafascicular neurons: an analysis of descending and ascending pathways. Brain Res. Bull. 42:1997;273-278.
61. Zhang L., Mitani A., Yanase H., Kataoka K. Continuous monitoring and regulating of brain temperature in the conscious and freely moving ischemic gerbil: effect of MK-801 on delayed neuronal death in hippocampal CA1. J. Neurosci. Res. 47:1997;440-448.