α(2A) subtype of presynaptic α2-adrenoceptors modulates the release of [3H]-noradrenaline from rat spinal cord

Brain Research Bulletin

Volumn 42, Issue 2, 1997, Pages 129-132

  Umeda, Eiichiro ^a,c   Satoh, Tetsuo ^b   Nagashima, Hideo ^c   Potter, Pamela E ^c   Tarkovács, Gabor ^d   Vizi, E Sylvester ^c,d  

^a Yokosuka Naval Hospital   (Japan)

^b NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

^c MONTEFIORE MEDICAL CENTER   (United States)

^d INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

ARC 239; BRL 44408; Noradrenaline release; Spinal cord; 2 Adrenoceptor subtype

Indexed keywords

ALPHA 2A ADRENERGIC RECEPTOR; NORADRENALIN;

ADRENALIN RELEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ISOTOPE LABELING; MALE; NONHUMAN; NORADRENERGIC SYSTEM; PRIORITY JOURNAL; RADIOACTIVITY; RAT; SPINAL CORD;

EID: 0030479336     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0361-9230(96)00223-7     Document Type: Article

References (31)

1. 2-adrenergic receptors. FASEB J. 6:832-839; 1992.
2. 2B-adrenergic receptor subtypes: Antagonist binding in tissues and cell lines containing only one subtype. J. Pharmacol. Exp. Ther. 245:600-607; 1988.
3. 2-adrenergic agonists during general anaesthesia. Anaesth. Pharmacol. Rev. 1:268-283; 1993.
4. 2A-adrenergic receptors are present in lower brainstem catecholaminergic and serotonergic neurons innervating spinal cord. Brain Res. 638:285-294; 1994.
5. 5. Hamalainen, M. M.; Pertovaara, A. The antinociceptive action of an alpha 2-adrenoceptor agonist in the spinal dorsal horn is due to a direct spinal action and not to activation of descending inhibition. Brain Res. Bull. 37:581-587; 1995.
6. 6. Hamalainen, M. M.; Pertovaara, A. The rostroventromedial medulla is not involved in alpha 2-adrenoceptor mediated antinociception in the rat. Neuropharmacology 32:1411-1418; 1993.
7. 2-adrenergic receptors. Mol. Pharmacol. 40:407-412; 1991.
8. 8. Howe, J. R.; Wang, J.-Y.; Yaksh, T. L. Selective antagonism of the antinociceptive effect of intrathecally applied alpha adrenergic agonists by intrathecal prazosin and intrathecal yohimbme. J. Pharmacol. Exp. Ther. 224:552-558; 1983.
9. 9. Jackson, C.; Eisenach, J. C. Spinal administration of α-adrenergic agonists. Anaesth. Pharmacol. Rev. 1:288-296; 1993.
10. 10. Kamisaki, Y.; Hamada, T.; Maeda, K.; Ishimura, M.; Itoh, T. Presynaptic α2 adrenoceptors inhibit glutamate release from rat spinal cord synaptosomes. J. Neurochem. 60:522-526; 1993.
11. 2-adrenoceptors modulating hippocampal norepinephrine release in rat. Brain Res. 674:238-244; 1995.
12. 2-adrenergic receptors subtype-specific antibodies. Mol. Pharmacol. 43:444-450; 1993.
13. 13. Kuraishi, Y.; Hirota, N.; Sato, Y.; Hino, Y.; Takagi, H. Evidence that substance and somatostatin transmit separate information related to pai in the spinal dorsal horn. Brain Res. 325:294-298; 1985.
14. 14. Lawhead, R. G.; Blaxall, H. S.; Bylund, D. B. α-2A is the predominant α-2 adrenergic receptor subtype in human spinal cord. Anesthesiology 77:9832-991; 1992.
15. 2-adrenoceptors of the medullary lateral reticular nucleus in spinal antinociception in rats. Brain Res. Bull. 37:633-638; 1995.
16. 2-adrenergic receptors in the OK cell, an opossum kidney cell line. J. Pharmacol. Exp. Ther. 244:571-578; 1988.
17. 3H] noradrenaline from rat spinal cord dorsal horn neurones. Eur. J. Pharmacol. 167:161-166; 1989.
18. 18. Rosin, D. L.; Zeng, D.; Stornetta, R. L.; Norton, F. R.; Riley, T.; Okusa, M. D.; Guyenet, P. G.; Lynch, K. R. Immunohistological localization of alpha 2A-adrenergic receptors in catecholaminergic and other brainstem neurons in the rat. Neuroscience 56:139-155; 1993.
19. 2-adrenoceptor subtypes. Annu. Rev. Pharmacol. Toxicol. 33:243-279; 1993.
20. 2D-adrenergic receptors in bovine pineal gland. Mol. Pharmacol. 40:235-241; 1991.
21. 2D-subtype. Eur. J. Pharmacol. 219:203-210; 1992.
22. 22. Starke, K. Presynaptic α-autoreceptors. Rev. Physiol. Biochem. Pharmacol. 107:73; 1987.
23. 23. Takano, Y.; Yaksh, T. L. Characterization of the pharmacology of intrathecally administered α-2 agonists and antagonists in rats. J. Pharmacol. Exp. Ther. 261:764-772; 1992.
24. 2-adrenoceptor-mediated inhibition of capsaicin-evoked release of glutamate from rat spinal horn slices. Neurosci. Lett. 188:137-139; 1995.
25. 25. Vizi, E. S. Presynaptic modulation of neurochemical transmission. Prog. Neurobiol. 12:181-290; 1979.
26. 26. Vizi, E. S. Nonsynaptic interactions between neurons: Modulation of neurochemical transmission. Pharmacological and clinical aspects. Chichester: John Wiley and Sons; 1984.
27. 27. Vizi, E. S.; Hársing, L. G., Jr.; Zimanyi, I.; Gaal, G. Release and turnover of noradrenaline in isolated median eminence: Lack of negative feedback modulation. Neuroscience 16:907-916; 1985.
28. 2-adrenoceptors. J. Pharmacol. Exp. Ther. 238:701-706; 1986.
29. 2-adrenoceptor antagonists. J. Med. Chem. 30:1355-1359; 1987.
30. 30. West, W.; Yeomans, D. C.; Proudfit, H. K. The function of noradrenergic neurons in mediating antinociception induced by electrical stimulation of the locus coeruleus in two different sources of Sprague-Dawley rats. Brain Res. 626:127-135; 1993.
31. 2B-arenoceptor subtypes. Eur. J. Pharmacol. 168:381-386; 1989.