Role of glutamate receptors and voltage-dependent calcium and sodium channels in the extracellular glutamate/aspartate accumulation and subsequent neuronal injury induced by oxygen/glucose deprivation in cultured hippocampal neurons

Journal of Pharmacology and Experimental Therapeutics

Volumn 285, Issue 1, 1998, Pages 178-185

  Kimura, Manami ^a   Sawada, Kohei ^a   Miyagawa, Takehiko ^a   Kuwada, Manabu ^a   Katayama, Kouichi ^a   Nishizawa, Yukio ^a  

^a EISAI CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; GLUTAMATE RECEPTOR; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; SODIUM CHANNEL; TETRODOTOXIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HIPPOCAMPUS; ISCHEMIA; NERVE CELL DEGENERATION; NERVE CELL LESION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ASPARTIC ACID; CALCIUM CHANNEL BLOCKERS; CELL HYPOXIA; CELLS, CULTURED; EXCITATORY AMINO ACID AGONISTS; GLUCOSE; GLUTAMIC ACID; HIPPOCAMPUS; ISCHEMIA; L-LACTATE DEHYDROGENASE; NEURONS; OXYGEN; RATS; RATS, WISTAR; RECEPTORS, GLUTAMATE; SODIUM CHANNELS;

EID: 0031969707     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Arvin B, Moncada C, Peillet EL, Chapman AG and Meldrum BS (1992) GYKI 52466 blocks the increase in extracellular glutamate induced by ischaemia. Neuro Report 3:235-238.
2. Arvin B, Lekieffre D, Graham JL, Moncada C, Chapman AG and Meldrum BS (1994) Effect of the non-NMDA receptor antagonist GYKI 52466 on the microdialysate and tissue concentrations of amino acids following transient forebrain ischemia J Neurochem 62:1458-1467.
3. Barbour B, Brew H and Attwell D (1988) Electrogcnic glutamate uptake in glial cells is activated by intracellular potassium. Nature 335: 433-435.
4. Bickler PE and Hansen BM (1994) Causes of calcium accumulation in rat cortical brain slices during hypoxia and ischemia: Role of ion channels and membrane damage. Brain Res 669:269-276.
5. Boening JA, Kass JS, Cottrell JE and Chambers G (1989) The effect of blocking sodium influx on anoxic damage in the rat hippocampal slice. Neuroscience 33: 263-268.
6. Buchan AM (1990) Do NMDA antagonists protect against cerebral ischemia: Are clinical trials warranted? Cerebrovasc Brain Metab Rev 2:1-26.
7. Buchan AM, Li H, Cho S and Pulsinelli WA (1991) Blockade of the AMPA receptor prevents CA1 hippocampal injury following severe but transient forebrain ischemia in adult rats. Neurosci Lett 132:255-258.
8. Christensen T, Bruhn T, Diemer NH and Schousboe A (1991) Effect of phenylsuccinate on potassium-and ischemia-induced release of glutamate in rat hippocampus monitored by microdialysis. Neurosci Lett 134:71-74.
9. Drejer J, Benveniste H, Diemer NH and Schousboe A (1985) Cellular origin of ischemia-induced glutamate release from brain tissue in vivo and in vitro. J Neurochem 45:145-151.
10. Ferkany JW, Zaczek R and Coyle JT (1982) Kainic acid stimulates excitatory amino acid neurotransmitter release at presynaptic receptors. Nature 298:757-759.
11. Friedman JE and Haddad GG (1994) Anoxia induces an increase in intracellular sodium in rat central neurons in vitro. Brain Res 663:329-334.
12. Gaspary HL, Simon RP and Graham SH (1994) BW1003C87 and NBQX but not CGS19755 reduce glutamate release and cerebral ischemie necrosis. Eur J Pharmac 262:197-203.
13. Goldberg MP and Choi DW (1993) Combined oxygen and glucose deprivation in cortical cell culture: calcium-dependent and calcium-independent mechanisms of neuronal injury. J Neurosei 13:3510-3524.
14. Goldberg MP, Weiss JW, Pham PC and Choi DW (1987) N-Methyl-D-aspartate receptors mediate hypoxic neuronal injury in cortical culture. J Pharmacol Exp Ther 243: 784-791.
15. Grotta J. Spydell J, Pettigrew C. Ostrow P and Hunter D (1986) The effect of nicardipine on neuronal function following ischemia. Stroke 17:213-219.
16. Ikeda M, Nakazawa T, Abe K, Kaneko and T, Yamatu K (1989) Extracellular accumulation of glutamate in the hippocampus induced by ischemia is not calcium dependent - in vitro and in vivo evidence. Neurosci Lett 96:202-206.
17. 2+ independent glutamate release, energy status following metabolic inhibition: possible relevance to hypoglycaemia and anoxia. Neuroscience 27:175-182.
18. Kimura M, Yamanishi Y, Hanada T, Kagaya T, Kuwada M, Watanabe T, Katayama K and Nishizawa Y (1995) Involvement of P-type calcium channels in high potassium-elicited release of neurotransmitters from rat brain slices. Neuroscience 66:609-615.
19. Koh J-Y and Choi DW (1987) Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay. J Neurosci Methods 20:83-90.
20. Koh J-Y and Choi DW (1991) Selective blockade of non-NMDA receptors does not block rapidly triggered glutamate-induced neuronal death. Brain Res 548:318-321.
21. Koretz B, Ahern KB, Wang N, Lustig HS and Greenberg DA (1994) Pre-and post-synaptic modulators of excitatory neurotransmission: Comparative effects on hypoxia/hypoglycemia in cortical cultures. Brain Res 643:334-337.
22. 46] agatoxin-TK, exerts blockade of P-type calcium channels in cerebellar Purkinje neurons. Mol Pharmac 46:587-593.
23. Kuwaki T, Satoh H, Ono T, Shibayama F, Yamashita T and Nishimura T (1989) Nilvadipine attenuates ischemie degradation of gerbil brain cytoskeletal proteins. Stroke 20:78-83.
24. Lipton SA and Rosenberg PA (1994) Excitatory amino acids as a final common pathway for neurologic disorders. N Engl J Med 330:613-622.
25. Lobner D and Lipton P (1993) Intracellular calcium levels and calcium fluxes in the CA1 region of the rat hippocampal slice during in vitro ischemia: relationship to electrophysiological cell damage. J Neurosci 13:4861-4871.
26. Madden KP, Clark WM, Marcoux FW, Probert Jr AW, Weber ML, Rivier J and Zinvin JA (1990) Treatment with conotoxin, an 'N-type' calcium channel blocker, in neuronal hypoxic-inchemic injury. Brain Res 537:256-262.
27. Mald JE and Burgessr K (1993) Adenosine triphyosphate depletion reverses sodium-dependent, neuronal uptake of glutamate in rat hippocampal slices. J Neurosci 13:4429-4444.
28. Martin RL, Lloid HGE and Cowan AI (1994) The early events of oxygen and glucose deprivation: setting the scene for neuronal death? Trends Neurosci 17:251-257.
29. Nicholls D and Attwell D (1990) The release and uptake of excitatory amino acids. Trends Pharmacol Sci 11:462-468.
30. Ooboshi H, Sadoshima S, Yao H, Nakahara T, Uchimura H and Fujishima M (1992) Inhibition of ischemia-induced dopamine release by ω-conotoxin, a calcium channel blocker, in the striatum of spontaneously hypertensive rats: in vivo brain dialysis study. J Neurochem 58:298-303.
31. 3H]glycine binding sites on the N-methyl-D-aspartate receptor complex. J Neurochem 54:699-702.
32. Prenen GHM, Go KG, Postema F, Zuiderveen F and Korf J (1988) Cerebral cation shifts in hypoxic-ischemic brain damage are prevented by the sodium channel blocker tetrodotoxin. Exp Neurol 99:118-132.
33. Probert AW, Borosky S, Marcoux FW and Taylor CP (1997) Sodium channel modulators prevent oxygen and glucose deprivation injury and glutamate release in rat neocortical cultures. Neuropharmacology 36:1031-1038.
34. 2+/calmodulin-dependent protein kinase II in cultures of hippocampal pyramidal neurons and astrocytes. J Neurosci 8:1039-1051.
35. Sheardown MJ, Nielsen EO, Hansen AJ, Jacobsen P and Honore T (1990) 2,3-Dihydroxy-6-nitro-7-sulfamoylbenzo(F)quinoxaline: A neuroprotectant for cerebral ischemia. Science 247:571-574.
36. Silverstein FS, Buchanan K, Hudson C and Johnston MV (1986) Flunarizine limits hypoxia-ischemia induced morphologic injury in immature rat brain. Stroke 17: 477-482.
37. + channels, glutamate release, and NMDA receptors mediates delayed neurodegeneration through nitric oxide formation. J Neuroci, 16:5004-5013.
38. Szatkowski M, Barbour B and Attwell D (1990) Non-vesicular release of glutamate from glial cells by reversed electrogenic glutamate uptake. Nature 348:443-446.
39. + channels as targets for neuroprotective drugs. Trends Neurosci 16:309-316.
40. Takakura S, Sogabe K, Satoh H, Mori J, Fujiwara T, Totsuka Z, Tokuma Y and Kohsaka M (1992) Nilvadipine as a neuroprotective calcium entry blocker in a rat model of global cerebral ischemia. A comparative study with incardipine hydrochloride. Meurosci Lett 141:199-202.
41. 2+ channel types coexist to regulate synaptosomal neurotransmitter release. Proc Natl Acad Sci USA 90: 9518-9522.
42. Wahl F, Obrenovitch TP, Hardy AM, Plotkine M, Boulu R and Symon L (1994) Extracellular glutamate during focal cerebral ischemia in rats: Time course and calcium dependency. J Neurochem 63: 1003-1011.
43. 2+-mediated injury in CNS white matter. Trends Neurosci 14:461-468.
44. weber ML and Taylor CP (1994) Damage from oxygen and glucose deprivation in hippocampal slices is prevented by tetrodotoxin, lidocaine and phenytoin without blockade of action potentials. Brain Res 664:164-177.
45. Xie Y, Dengler K, Zacharias E, Wilffert B and Tegtmeier F (1994) Effects of the sodium channel blocker tetrodotoxin (TTX) on cellular ion homeostasis in rat brain subjected to complete ischemia. Brain Res 652:216-224.
46. Yamada K, Teraoka T, Morita S, Hasegawa T and Nabeshima T (1994) ω-Conotoxin GVIA protects against ischemia-induced neuronal death in the Mongolian gerbil but not against quinolinic acid-induced neurotoxicity in the rat. Neuropharmacollogy 33:251-254.
47. Yamasaki Y, Kogure K, Hara H, Ban H and Akaike N (1991) The possible involvement of tetrodotoxin-sensitive ion channels in ischemic neuronal damage in the rat hippocampus. Neurosci Lett 121:251-254.