Enhancement of 5-HT(1B) and 5-HT(1D) receptor antagonist effects on extracellular 5-HT levels in the guinea-pig brain following concurrent 5-HT(1A) or 5-HT re-uptake site blockade

Neuropharmacology

Volumn 38, Issue 9, 1999, Pages 1409-1419

  Roberts, Claire ^a   Boyd, David F ^a   Middlemiss, Derek N ^a   Routledge, Carol ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

5 HT(1A) receptor antagonists; 5 HT(1B 1D); Guinea pig; Microdialysis

Indexed keywords

2,3,6,7 TETRAHYDRO 1' METHYL 5 [[2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL) 4 BIPHENYLYL]CARBONYL]SPIRO[FURO[2,3 F]INDOLE 3,4' PIPERIDINE]; AUTORECEPTOR; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; N [4 METHOXY 3 (4 METHYL 1 PIPERAZINYL)PHENYL] 2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL)[1,1' BIPHENYL] 4 CARBOXAMIDE; PAROXETINE; RECEPTOR SUBTYPE; SEROTONIN 1A RECEPTOR; SEROTONIN 1B RECEPTOR; SEROTONIN 1D RECEPTOR; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR; SEROTONIN; SEROTONIN 1 RECEPTOR; SEROTONIN UPTAKE INHIBITOR;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DORSAL RAPHE NUCLEUS; FRONTAL CORTEX; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; INTRACEREBRAL DRUG ADMINISTRATION; MALE; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; SEROTONIN BRAIN LEVEL; ANALYSIS OF VARIANCE; ANIMAL; BRAIN; DRUG EFFECT; GUINEA PIG; METABOLISM; PREFRONTAL CORTEX;

ANALYSIS OF VARIANCE; ANIMALS; BRAIN; GUINEA PIGS; HIPPOCAMPUS; MALE; MICRODIALYSIS; PREFRONTAL CORTEX; RECEPTOR, SEROTONIN, 5-HT1B; RECEPTOR, SEROTONIN, 5-HT1D; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; SEROTONIN; SEROTONIN ANTAGONISTS; SEROTONIN UPTAKE INHIBITORS;

EID: 0032586736     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(99)00051-9     Document Type: Article

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