Elevated basal trough levels of corticosterone suppress hippocampal 5- hydroxytryptamine(1A) receptor expression in adrenally intact rats: Implication for the pathogenesis of depression

Neuroscience

Volumn 80, Issue 2, 1997, Pages 419-426

  Meijer, O C ^a,b   Van Oosten, R V ^a   De Kloet, E R ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

8 OH DPAT; Glucocorticoid; Hippocampus; Hypercorticism; Mineralocorticoid; Serotonin

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; CORTICOSTERONE; GLUCOCORTICOID RECEPTOR; MESSENGER RNA; MINERALOCORTICOID RECEPTOR; SEROTONIN 1A RECEPTOR;

ADRENALECTOMY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CIRCADIAN RHYTHM; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; CORTICOSTERONE RELEASE; DEPRESSION; HIPPOCAMPUS; HYPOPHYSIS ADRENAL SYSTEM; IN SITU HYBRIDIZATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; THYMUS;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ADRENAL GLANDS; ANIMALS; CIRCADIAN RHYTHM; CORTICOSTERONE; DEPRESSIVE DISORDER; DRUG IMPLANTS; HIPPOCAMPUS; MALE; RATS; RATS, WISTAR; RECEPTORS, SEROTONIN; RNA, MESSENGER; SEROTONIN AGONISTS;

EID: 0030839470     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(97)00008-0     Document Type: Article

References (50)

1. Akana S. F., Scribner K. A., Bradbury M. J., Strack A. M., Walker C.-D. and Dallman M. F. (1992) Feedback sensitivity of the rat hypothalamo-pituitary-adrenal axis and its capacity to adjust to exogenous corticosterone. Endocrinology 131, 585-594.
2. 1a receptor gene. J. biol. Chem. 10, 5825-5832.
3. Azmitia E. C. and McEwen B. S. (1974) Adrenocortical influence on rat tryptophan hydroxylase activity. Brain Res. 78, 291-302.
4. 1 agonists in the rat. Neuroendocrinology 50, 241-247.
5. Barden N., Reul J. M. H. M. and Holsboer F. (1995) Do antidepressants stabilize mood through actions on the hypothalamic-pituitary-adrenocortical system? Trends Neurosci. 18, 6-10.
6. Bech P. (1990) A meta-analysis of the antidepressant properties of serotonin reuptake inhibitors. Int. Rev. Psychiatry 2, 209-211.
7. 1a receptor-mediated hyperpolarization in area CA1 hippocampal neurons. Neuropsychopharmacology 14, 27-33.
8. 1A) messenger ribonucleic acid abundance, and serotonin levels parallel the activity of the hypothalamopituitary-adrenal axis in rat. J. Neurochem. 59, 1062-1070.
9. 1A receptor gene expression by dexamethasone. Neuropsychopharmacology 10, 215-222.
10. Chaouloff F. (1995) Regulation of 5-HT receptors by corticosteroids: where do we stand? Fundam. clin. Pharmac. 9, 219-233.
11. Dallman M. F., Akana S. F., Cascio C. S., Darlington D. N., Jacobson L. and Levin N. (1987) Regulation of ACTH secretion: variations on a theme of B. Recent Prog. Horm. Res. 43, 113-173.
12. Dallman M. F., Levin N., Cascio C. S., Akana S. F., Jacobson L. and Kuhn R. W. (1989) Pharmacological evidence that inhibition of diurnal adrenocorticotropin secretion by corticosteroids is mediated via type I corticosterone-preferring receptors. Endocrinology 124, 2844-2850.
13. De Kloet E. R. (1991) Brain corticosteroid receptor balance and homeostatic control. Front. Neuroendocr. 12, 95-164.
14. Deakin J. F. W., Pennell I., Upadhyaha A. J. and Lofhouse R. (1990) A neuroendocrine study of 5-HT function in depression: evidence for biological mechanisms of endogenous and psychosocial causation. Psychopharmacology 101, 85-92.
15. Dickinson S. L., Kennett G. A. and Curzon G. (1985) Reduced 5-hydroxytryptamine-dependent behaviour in rats following chronic corticosterone treatment. Brain Res. 345, 10-18.
16. 1A-receptors under psychosocial stress. J. Neurosci. 15, 7132-7140.
17. Gemma C., De Luigi A. and De Simoni M. G. (1994) Permissive role of glucocorticoids on interleukin-1 activation of the hypothalamic serotonergic system. Brain Res. 651, 169-173.
18. Gold P. W., Goodwin M. D. and Chrousos G. P. (1988) Clinical and biochemical manifestations of depression; relation to the neurobiology of stress II. New Engl. J. Med. 319, 413-420.
19. Gray J. A. (1982) The Neuropsychology of Anxiety: An Enquiry into the Functions of the Septo-Hippocampal System. Oxford University Press, Oxford.
20. 1a responsiveness in CA1 pyramidal neurons by in vivo activation of corticosteroid receptors. J. Neuroendocr. 8, 433-438.
21. Hesen W., Karst H., Meijer O. C., Cole T. J., Schmid W., De Kloet E. R., Schütz G. and Joëls M. (1996) Hippocampal cell responses in mice with a targeted glucocorticoid receptor gene disruption. J. Neurosci. 16, 6766-6774.
22. Heuser I., Yassouridis A. and Holsboer F. (1994) The combined dexamethasone/CRH test: a refined laboratory test for psychiatric disorders. J. psychiat. Res. 28, 341-356.
23. Holmes M. C., Yau J. L. W., French K. L. and Seckl J. R. (1995) The effect of adrenalectomy on 5-hydroxytryptamine and corticosteroid receptor subtype messenger RNA expression in the rat. Neuroscience 64, 327-337.
24. Joëls M. and De Kloet E. R. (1992) Coordinative mineralocorticoid and glucocorticoid receptor-mediated control of responses to serotonin in rat hippocampus. Neuroendocrinology 55, 344-350.
25. Joëls M. and De Kloet E. R. (1994) Mineralocorticoid and glucocorticoid receptors in the brain. Implications for ion permeability and transmitter systems. Prog. Neurobiol. 43, 1-36.
26. Korte S. M., de Boer S. F., De Kloet E. R. and Bohus B. (1995) Anxiolytic-like effects of selective mineralocorticoid and glucocorticoid antagonists on fear-enhanced behavior in the elevated plus-maze. Psychoneuroendocrinology 20, 385-394.
27. 1A receptor expression in forebrain regions of aggressive house mice. Brain Res. 736, 338-343.
28. 2 receptor binding and 5-HT transporter mRNA expression in rat brain. Brain Res. 648, 157-161.
29. 1a receptor functioning in the rat dorsal raphe nucleus. Neuropharmacology 34, 1201-1210.
30. McKittrick C. R., Blanchard D. C., Blanchard R. J., McEwen B. S. and Sakai R. R. (1995) Serotonin receptor binding in a colony model of chronic social stress. Biol. Psychiatry 37, 383-393.
31. McNaughton N. (1993) Stress and behavioural inhibition. In Stress: From Synapse to Syndrome (eds Stanford S. C. and Salmon P.), pp. 191-206. Academic Press, London.
32. 1A receptor mRNA and binding in transgenic mice with a targeted disruption of the glucocorticoid receptor. Molec. Brain Res. in press.
33. 1a receptor mRNA in rat dentate gyrus. Eur. J. Pharmac., Molec. Pharm. 266, 255-261.
34. 1A receptor mRNA by corticosterone. J. Neuroendocr. 7, 653-657.
35. 1b receptors in the dorsal hippocampus and cortex of the rat. Neuroendocrinology 55, 444-450.
36. Oitzl M. S., van Haarst A. D. and De Kloet E. R. (1995) Corticosterone, brain mineralocorticoid receptors (MRs) and the activity of the hypothalamus-pituitary-adrenal axis: the Lewis rat as an example of increased central MR capacity and a hyporesponsive HPA-axis. Psychoneuroendocrinology 20, 655-675.
37. Pinto W. and Battaglia G. (1994) Comparative recovery kinetics of 5-hydroxytryptamine 1A, 1B and 2A receptor subtypes in rat cortex after receptor inactivation: evidence for differences in receptor production and degradation. Molec. Pharmac. 48, 1111-1119.
38. Price L. H. (1990) Serotonin reuptake inhibitors in depression and anxiety. An overview. Ann. clin. Psychiatry 2, 165-172.
39. Ratka A., Sutanto W., Bloemers M. and De Kloet E. R. (1989) On the role of brain mineralocorticoid (type I) and glucocorticoid (type II) receptors in neuroendocrine regulations. Neuroendocrinology 50, 117-123.
40. Reul J. M. H. M. and De Kloet E. R. (1985) Two receptor systems for corticosterone in rat brain: microdistribution and differential occupation. Endocrinology 117, 2505-2511.
41. Reul J. M. H. M., van den Bosch J. R. and De Kloet E. R. (1987) Relative occupation of type-I and type-II corticosteroid receptors in the rat brain following stress and dexamethasone treatment: functional implications. J. Endocr. 115, 459-467.
42. 1 receptor sites in the rat brain: an autoradiographic study. Eur. J. Pharmac. 117, 55-67.
43. Singh V. B., Corley K. C., Krieg R. J., Phan T.-H. and Boadle-Biber M. C. (1994) Sound stress activation of tryptophan hydroxylase blocked by hypophysectomy and intracranial RU 38486. Eur. J. Pharmac. 256, 177-184.
44. Singh V. B., Phan T.-H., Corley K. C. and Boadle-Biber M. C. (1992) Increase in cortical and midbrain tryptophan hydroxylase activity by intracerebroventricular administration of corticotropin releasing factor: block by adrenalectomy, by RU 38486 and by bilateral lesions to the central nucleus of the amygdala. Neurochem. Int. 20, 81-92.
45. Spencer R. L., Miller A. H., Moday H., Stein M. and McEwen B. S. (1993) Diurnal differences in basal and acute stress levels of type I and type II adrenal steroid receptor activition in neural and immune tissues. Endocrinology 133, 1941-1950.
46. Sternberg E. M. and Wilder R. L. (1989) The role of hypothalamic-pituitary-ardenal axis in an experimental model of arthritis. Prog. neuroendocr. Immun. 2, 102-108.
47. Trapp T., Rupprecht R., Castr'n M., Reul J. M. H. M. and Holsboer F. (1994) Heterodimerization between mineralocorticoid receptor and glucocorticoid receptor: a new principle of glucocorticoid action in the CNS. Neuron 13, 1457-1462.
48. Veldhuis H. D., van Koppen C., van Ittersum M. and De Kloet E. R. (1982) Specificity of adrenal steroid receptor system in the rat hippocampus. Endocrinology 110, 2044-2051.
49. 1a presynaptic function in the mouse. Psychopharmacology 114, 360-364.
50. 1A receptors by corticosteroid hormones. Molec. Brain Res. 29, 23-34.