Immobilized artificial membranes - Screens for drug membrane interactions

Advanced Drug Delivery Reviews

Volumn 23, Issue 1-3, 1997, Pages 229-256

  Yang, Cheng Y ^a   Cai, Song J ^a   Liu, Hanlan ^a   Pidgeon, Charles ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

bioavailability; chromatography; diffusion; drug screen; hydrophobicity parameter; IAM; in vitro model; partitioning coefficient; passive transport; permeability; pharmacokinetics

Indexed keywords

CELL MEMBRANES; CHROMATOGRAPHY; COMPUTER SIMULATION; DIFFUSION; DRUG THERAPY; MATHEMATICAL MODELS; MOLECULAR DYNAMICS; MONOLAYERS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ORGANIC COMPOUNDS; PHARMACOKINETICS;

BIOAVAILABILITY; DRUG SCREEN; HYDROPHOBICITY PARAMETER; IMMOBILIZED ARTIFICIAL MEMBRANES; PARTITION COEFFICIENT; PASSIVE TRANSPORT; PHOSPHOLIPIDS;

DRUG INTERACTIONS;

ACETYLSALICYLIC ACID; ALCOHOL; ALPRENOLOL; AMINO ACID; ARGIPRESSIN; ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BILE SALT; CORTICOSTERONE; HYDROCORTISONE; IMIDAZOLINE DERIVATIVE; LIPOSOME; LY 211193; LY 257290; METOPROLOL; PHENAZONE; PHOSPHATIDIC ACID; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLGLYCEROL; PHOSPHATIDYLSERINE; PROPRANOLOL; SALICYLIC ACID; STEROID; TERBUTALINE; THEOPHYLLINE; UNCLASSIFIED DRUG; UNINDEXED DRUG; WARFARIN;

ARTIFICIAL MEMBRANE; BRAIN; CELL STRAIN CACO 2; CHROMATOGRAPHY; COVALENT BOND; HUMAN; HYDROPHOBICITY; IMMOBILIZATION; INTESTINE ABSORPTION; MEMBRANE BINDING; MEMBRANE PERMEABILITY; MEMBRANE TRANSPORT; MOLECULAR DYNAMICS; NONHUMAN; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; REVIEW; SCREENING; SKIN;

EID: 0031024064     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(96)00438-3     Document Type: Review

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