메뉴 건너뛰기




Volumn 400, Issue 1-2, 1998, Pages 15-24

Variation in DNA repair is a factor in cancer susceptibility: A paradigm for the promises and perils of individual and population risk estimation?

Author keywords

Cancer susceptibility; DNA repair; Genetic variation; Risk estimation

Indexed keywords

CARCINOGEN; DNA;

EID: 0032565543     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(98)00059-1     Document Type: Article
Times cited : (212)

References (72)
  • 4
    • 0030902227 scopus 로고    scopus 로고
    • Population genetics of BRCA1 and BRCA2
    • [4] C.I. Szabo, M.C. King, Population genetics of BRCA1 and BRCA2, Am. J. Hum. Genet. 60 (1997) 1013-1020.
    • (1997) Am. J. Hum. Genet. , vol.60 , pp. 1013-1020
    • Szabo, C.I.1    King, M.C.2
  • 6
    • 0028867842 scopus 로고
    • Mismatch repair: Mechanisms and relationship to cancer susceptibility
    • [6] R.D. Kolodner, Mismatch repair: mechanisms and relationship to cancer susceptibility, Trends Biochem. Sci. 20 (1995) 397-401.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 397-401
    • Kolodner, R.D.1
  • 7
    • 0031579994 scopus 로고    scopus 로고
    • Is there a lung-cancer susceptibility gene?
    • [7] M.J. Renan, Is there a lung-cancer susceptibility gene?, Int. J. Cancer 74 (1997) 359-361.
    • (1997) Int. J. Cancer , vol.74 , pp. 359-361
    • Renan, M.J.1
  • 9
    • 0031027752 scopus 로고    scopus 로고
    • Risk factors for childhood melanoma in Queensland, Australia
    • [9] D.C. Whiteman, P. Valery, W. McWhirter, A.C. Green, Risk factors for childhood melanoma in Queensland, Australia, Int. J. Cancer 70 (1997) 26-31.
    • (1997) Int. J. Cancer , vol.70 , pp. 26-31
    • Whiteman, D.C.1    Valery, P.2    McWhirter, W.3    Green, A.C.4
  • 10
    • 0029900122 scopus 로고    scopus 로고
    • Studies of the mortality of atomic bomb survivors: Report 12, part 1. Cancer: 1950-1990
    • [10] D.A. Pierce, Y. Shimizu, D.L. Preston, M. Vaeth, K. Mabuchi, Studies of the mortality of atomic bomb survivors: Report 12, Part 1. Cancer: 1950-1990, Radiat. Res. 146 (1996) 1-27.
    • (1996) Radiat. Res. , vol.146 , pp. 1-27
    • Pierce, D.A.1    Shimizu, Y.2    Preston, D.L.3    Vaeth, M.4    Mabuchi, K.5
  • 11
    • 0027218972 scopus 로고
    • Breast cancer epidemiology: Summary and future directions
    • [11] J.L. Kelsey, Breast cancer epidemiology: summary and future directions, Epidemiol. Rev. 15 (1993) 256-263.
    • (1993) Epidemiol. Rev. , vol.15 , pp. 256-263
    • Kelsey, J.L.1
  • 12
    • 0027260662 scopus 로고
    • Genetic susceptibility to cancer
    • [12] M.R. Spitz, M.L. Bondy, Genetic susceptibility to cancer, Cancer 72 (1993) 991-995.
    • (1993) Cancer , vol.72 , pp. 991-995
    • Spitz, M.R.1    Bondy, M.L.2
  • 13
    • 0026708293 scopus 로고
    • Lung cancer detection and prevention: Evidence for an interaction between smoking and genetic predisposition
    • [13] T.A. Sellers, J.D. Potter, J.E. Bailey-Wilson, S.S. Rich, H. Rothschild, R.C. Elston, Lung cancer detection and prevention: evidence for an interaction between smoking and genetic predisposition, Cancer Res. 52 (1992) 2694s-2697s.
    • (1992) Cancer Res. , vol.52
    • Sellers, T.A.1    Potter, J.D.2    Bailey-Wilson, J.E.3    Rich, S.S.4    Rothschild, H.5    Elston, R.C.6
  • 14
    • 0028641692 scopus 로고
    • Pharmacogenetics: Detecting sensitive populations
    • [14] P.G. Shields, Pharmacogenetics: detecting sensitive populations, Environ. Health Perspect. 11 (1994) 81-87.
    • (1994) Environ. Health Perspect. , vol.11 , pp. 81-87
    • Shields, P.G.1
  • 16
    • 0029021815 scopus 로고
    • Diagnosis of polymorphisms in carcinogen-activating and inactivating enzymes and cancer susceptibility - A review
    • [16] H. Raunio, K. Husgafvel-Pursiainen, S. Anttila, E. Hietanen, A. Hirvonen, O. Pelkonen, Diagnosis of polymorphisms in carcinogen-activating and inactivating enzymes and cancer susceptibility - a review, Gene 159 (1995) 113-121.
    • (1995) Gene , vol.159 , pp. 113-121
    • Raunio, H.1    Husgafvel-Pursiainen, K.2    Anttila, S.3    Hietanen, E.4    Hirvonen, A.5    Pelkonen, O.6
  • 17
    • 0028961525 scopus 로고
    • Genetic polymorphism and cancer susceptibility: Fourteenth sapporo cancer seminar
    • [17] F.J. Gonzalez, Genetic polymorphism and cancer susceptibility: fourteenth Sapporo Cancer Seminar, Cancer Res. 55 (1995) 710-715.
    • (1995) Cancer Res. , vol.55 , pp. 710-715
    • Gonzalez, F.J.1
  • 18
    • 0030975938 scopus 로고    scopus 로고
    • The 1st UICC symposium on the molecular epidemiology of cancer. Union Internationale Contre le Cancer
    • [18] T. Kitagawa, The 1st UICC symposium on the molecular epidemiology of cancer. Union Internationale Contre le Cancer, Int. J. Cancer 71 (1997) 712-714.
    • (1997) Int. J. Cancer , vol.71 , pp. 712-714
    • Kitagawa, T.1
  • 21
    • 0031440755 scopus 로고    scopus 로고
    • Susceptibility to lung cancer in light smokers associated with Cyp1A1 polymorphisms in Mexican- and African-Americans
    • [21] N. Ishibe, J.K. Wienke, Z.-f. Zuo, A. McMillan, M. Spitz, K.T. Kelsey, Susceptibility to lung cancer in light smokers associated with Cyp1A1 polymorphisms in Mexican- and African-Americans, Cancer Epidemiol. Biomarkers Prev. 6 (1997) 1075-1080.
    • (1997) Cancer Epidemiol. Biomarkers Prev. , vol.6 , pp. 1075-1080
    • Ishibe, N.1    Wienke, J.K.2    Zuo, Z.-F.3    McMillan, A.4    Spitz, M.5    Kelsey, K.T.6
  • 22
    • 0030932612 scopus 로고    scopus 로고
    • Molecular epidemiology: Low-dose carcinogens and genetic susceptibility
    • [22] P. Vineis, Molecular epidemiology: low-dose carcinogens and genetic susceptibility, Int. J. Cancer 71 (1997) 1-3.
    • (1997) Int. J. Cancer , vol.71 , pp. 1-3
    • Vineis, P.1
  • 23
    • 0029815779 scopus 로고    scopus 로고
    • Combined analysis of inherited polymorphisms in arylamine N-acetyltransferase 2, glutathione S-transferases M1 and T1, microsomal epoxide hydrolase and cytochrome P450 enzymes as modulators of bladder cancer risk
    • [23] J. Brockmoller, I. Cascorbi, R. Kerb, I. Roots, Combined analysis of inherited polymorphisms in arylamine N-acetyltransferase 2, glutathione S-transferases M1 and T1, microsomal epoxide hydrolase and cytochrome P450 enzymes as modulators of bladder cancer risk, Cancer Res. 56 (1996) 3915-3925.
    • (1996) Cancer Res. , vol.56 , pp. 3915-3925
    • Brockmoller, J.1    Cascorbi, I.2    Kerb, R.3    Roots, I.4
  • 25
    • 0010228068 scopus 로고    scopus 로고
    • Molecular cytogenetic analysis of DNA lesions using FISH technology
    • [25] J.D. Tucker, Molecular cytogenetic analysis of DNA lesions using FISH technology, Mutation Res. 400 (1998) .
    • (1998) Mutation Res. , vol.400
    • Tucker, J.D.1
  • 26
    • 0010282656 scopus 로고    scopus 로고
    • Biomarkers as tools to enhance public health
    • [26] R.J. Albertini, Biomarkers as tools to enhance public health, Mutation Res. 400 (1998) .
    • (1998) Mutation Res. , vol.400
    • Albertini, R.J.1
  • 27
    • 0022884495 scopus 로고
    • Measurements of the frequency of human erythrocytes with gene expression loss phenotypes at the glycophorin A locus
    • [27] R.G. Langlois, W.L. Bigbee, R.H. Jensen, Measurements of the frequency of human erythrocytes with gene expression loss phenotypes at the glycophorin A locus, Hum. Genet. 74 (1986) 353-362.
    • (1986) Hum. Genet. , vol.74 , pp. 353-362
    • Langlois, R.G.1    Bigbee, W.L.2    Jensen, R.H.3
  • 28
    • 0010285596 scopus 로고
    • Somatic cell mutations in humans detected by image analysis of immunofluorescently stained erythrocytes
    • G. Burger, J.S. Ploem, K. Goerttler (Eds.), Academic Press, San Diego
    • [28] N.P. Verwoerd, L.F. Bernini, J. Bonnet, H.J. Tanke, A.T. Natarajan, et al., Somatic cell mutations in humans detected by image analysis of immunofluorescently stained erythrocytes, in: G. Burger, J.S. Ploem, K. Goerttler (Eds.), Clinical Cytometry and Histometry, Academic Press, San Diego, 1987, pp. 465-469.
    • (1987) Clinical Cytometry and Histometry , pp. 465-469
    • Verwoerd, N.P.1    Bernini, L.F.2    Bonnet, J.3    Tanke, H.J.4    Natarajan, A.T.5
  • 29
    • 0028157494 scopus 로고
    • Somatic mutant frequency, mutation rates and mutational spectra in the human population in vivo
    • International Commission for Protection Against Environmental Mutagens and Carcinogens. Working paper no. 3
    • [29] J. Cole, T.R. Skopek, International Commission for Protection Against Environmental Mutagens and Carcinogens. Working paper no. 3. Somatic mutant frequency, mutation rates and mutational spectra in the human population in vivo, Mutation Res. 304 (1994) 33-105.
    • (1994) Mutation Res. , vol.304 , pp. 33-105
    • Cole, J.1    Skopek, T.R.2
  • 31
    • 0029166930 scopus 로고
    • The effects of age and lifestyle factors on the accumulation of cytogenetic damage as measured by chromosome painting
    • [31] M.J. Ramsey, D.H. Moore II, J.F. Briner, D.A. Lee, L.A. Olsen, J.R. Senft, J.D. Tucker, The effects of age and lifestyle factors on the accumulation of cytogenetic damage as measured by chromosome painting, Mutation Res. 338 (1995) 95-106.
    • (1995) Mutation Res. , vol.338 , pp. 95-106
    • Ramsey, M.J.1    Moore D.H. II2    Briner, J.F.3    Lee, D.A.4    Olsen, L.A.5    Senft, J.R.6    Tucker, J.D.7
  • 32
    • 0024854474 scopus 로고
    • Molecular analyses of in vivo hprt mutations in human T-lymphocytes: III. Longitudinal study of hprt gene structural alterations and T-cell clonal origins
    • [32] J.A. Nicklas, T.C. Hunter, J.P. O'Neill, R.J. Albertini, Molecular analyses of in vivo hprt mutations in human T-lymphocytes: III. Longitudinal study of hprt gene structural alterations and T-cell clonal origins, Mutation Res. 215 (1989) 147-160.
    • (1989) Mutation Res. , vol.215 , pp. 147-160
    • Nicklas, J.A.1    Hunter, T.C.2    O'Neill, J.P.3    Albertini, R.J.4
  • 33
    • 0010281211 scopus 로고    scopus 로고
    • Human in vivo somatic mutation measured at two loci: Individuals with stably elevated erythrocyte glycophorin A (GPA) variant frequencies exhibit normal T-lymphocyte hprt mutant frequencies
    • in press
    • [33] W.L. Bigbee, J.C. Fuscoe, A.G. Gorvad, K. Harrington-Brock, I.M. Jones, D.H. Moore II, M.M. Moore, C.L. Strout, C.B. Thomas, S.G. Grant, Human in vivo somatic mutation measured at two loci: individuals with stably elevated erythrocyte glycophorin A (GPA) variant frequencies exhibit normal T-lymphocyte hprt mutant frequencies, Mutation Res. (1997) in press.
    • (1997) Mutation Res.
    • Bigbee, W.L.1    Fuscoe, J.C.2    Gorvad, A.G.3    Harrington-Brock, K.4    Jones, I.M.5    Moore D.H. II6    Moore, M.M.7    Strout, C.L.8    Thomas, C.B.9    Grant, S.G.10
  • 35
    • 0029557033 scopus 로고
    • Analysis of mutation at the hprt locus in human T lymphocytes
    • [35] B. Lambert, T. Bastlova, A.M. Osterholm, S.M. Hou, Analysis of mutation at the hprt locus in human T lymphocytes, Toxicol. Lett. 83 (1995) 323-333.
    • (1995) Toxicol. Lett. , vol.83 , pp. 323-333
    • Lambert, B.1    Bastlova, T.2    Osterholm, A.M.3    Hou, S.M.4
  • 36
    • 0010254618 scopus 로고    scopus 로고
    • Evidence that GSTT1 affects the induction of glycophorin A variant cells in smokers
    • [36] R.G. Langlois, A.M. Lockhart, M.A. Watson, C.L. Thompson, D.A. Bell, Evidence that GSTT1 affects the induction of glycophorin A variant cells in smokers, Environ. Mol. Mutagen. 27 (1996) 39, Suppl. 27.
    • (1996) Environ. Mol. Mutagen. , vol.27 , Issue.SUPPL. 27 , pp. 39
    • Langlois, R.G.1    Lockhart, A.M.2    Watson, M.A.3    Thompson, C.L.4    Bell, D.A.5
  • 37
    • 0028242630 scopus 로고
    • Cancer risk in humans predicted by increased levels of chromosomal aberrations in lymphocytes: Nordic study group on the health risk of chromosome damage
    • [37] L. Hagmar, A. Brogger, I.L. Hansteen, S. Heim, B. Hogstedt, L. Knudsen, B. Lambert, K. Linnainmaa, F. Mitelman, I. Nordenson et al., Cancer risk in humans predicted by increased levels of chromosomal aberrations in lymphocytes: Nordic study group on the health risk of chromosome damage, Cancer Res. 54 (1994) 2919-2922.
    • (1994) Cancer Res. , vol.54 , pp. 2919-2922
    • Hagmar, L.1    Brogger, A.2    Hansteen, I.L.3    Heim, S.4    Hogstedt, B.5    Knudsen, L.6    Lambert, B.7    Linnainmaa, K.8    Mitelman, F.9    Nordenson, I.10
  • 38
    • 0029654349 scopus 로고
    • Editing DNA replication and recombination by mismatch repair: From bacterial genetics to mechanisms of predisposition to cancer in humans
    • [38] M. Radman, I. Matic, J.A. Halliday, F. Taddei, Editing DNA replication and recombination by mismatch repair: from bacterial genetics to mechanisms of predisposition to cancer in humans, Philos. Trans. R. Soc. London Ser. B 347 (1995) 97-103.
    • (1995) Philos. Trans. R. Soc. London Ser. B , vol.347 , pp. 97-103
    • Radman, M.1    Matic, I.2    Halliday, J.A.3    Taddei, F.4
  • 39
    • 0029616260 scopus 로고
    • DNA repair fine structure and its relations to genomic instability
    • [39] V.A. Bohr, DNA repair fine structure and its relations to genomic instability, Carcinogenesis 16 (1995) 2885-2892.
    • (1995) Carcinogenesis , vol.16 , pp. 2885-2892
    • Bohr, V.A.1
  • 42
    • 0001415829 scopus 로고
    • Xeroderma pigmentosum and cockayne syndrome
    • C.R. Scriver, A.L. Beudet, W.S. Sly, D. Valle (Eds.), McGraw-Hill, New York
    • [42] J.E. Cleaver, K.H. Kraemer, Xeroderma pigmentosum and Cockayne syndrome, in: C.R. Scriver, A.L. Beudet, W.S. Sly, D. Valle (Eds.), The Metabolic and Molecular Basis of Inherited Disease, McGraw-Hill, New York, 1995, pp. 4393-4419.
    • (1995) The Metabolic and Molecular Basis of Inherited Disease , pp. 4393-4419
    • Cleaver, J.E.1    Kraemer, K.H.2
  • 43
    • 0029931026 scopus 로고    scopus 로고
    • Xeroderma pigmentosum, cockayne syndrome and trichothiodystrophy: Do the genes explain the diseases?
    • [43] G. Chu, L. Mayne, Xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy: do the genes explain the diseases?, Trends Genet. 12 (1996) 187-192.
    • (1996) Trends Genet. , vol.12 , pp. 187-192
    • Chu, G.1    Mayne, L.2
  • 44
    • 0029957245 scopus 로고    scopus 로고
    • XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly (ADP-ribose) polymerase, and DNA ligase III is a novel molecular 'nick-sensor' in vitro
    • [44] K.W. Caldecott, S. Aoufouchi, P. Johnson, S. Shall, XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly (ADP-ribose) polymerase, and DNA ligase III is a novel molecular 'nick-sensor' in vitro, Nucleic Acids Res. 24 (1996) 4387-4394.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 4387-4394
    • Caldecott, K.W.1    Aoufouchi, S.2    Johnson, P.3    Shall, S.4
  • 45
    • 0029842307 scopus 로고    scopus 로고
    • Reconstitution of DNA base excision-repair with purified human proteins: Interaction between DNA polymerase beta and the XRCC1 protein
    • [45] Y. Kubota, R.A. Nash, A. Klungland, P. Schar, D.E. Barnes, T. Lindahl, Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein, EMBO J. 15 (1996) 6662-6670.
    • (1996) EMBO J. , vol.15 , pp. 6662-6670
    • Kubota, Y.1    Nash, R.A.2    Klungland, A.3    Schar, P.4    Barnes, D.E.5    Lindahl, T.6
  • 47
    • 0026701365 scopus 로고
    • The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine)
    • [47] M.L. Michaels, J.H. Miller, The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine), J. Bacteriol. 174 (1992) 6321-6325.
    • (1992) J. Bacteriol. , vol.174 , pp. 6321-6325
    • Michaels, M.L.1    Miller, J.H.2
  • 48
    • 0023015325 scopus 로고
    • Mutagenesis by apurinic / apyrimidinic sites
    • [48] L.A. Loeb, B.D. Preston, Mutagenesis by apurinic / apyrimidinic sites, Annu. Rev. Genet. 20 (1986) 201-230.
    • (1986) Annu. Rev. Genet. , vol.20 , pp. 201-230
    • Loeb, L.A.1    Preston, B.D.2
  • 49
    • 0029001182 scopus 로고
    • Excision repair in mammalian cells
    • [49] A. Sancar, Excision repair in mammalian cells, J. Biol. Chem. 270 (1995) 15915-15918.
    • (1995) J. Biol. Chem. , vol.270 , pp. 15915-15918
    • Sancar, A.1
  • 50
    • 0028960865 scopus 로고
    • Mammalian mutants defective in the response to ionizing radiation-induced DNA damage
    • [50] M.Z. Zdzienicka, Mammalian mutants defective in the response to ionizing radiation-induced DNA damage, Mutation Res. 336 (1995) 203-213.
    • (1995) Mutation Res. , vol.336 , pp. 203-213
    • Zdzienicka, M.Z.1
  • 51
    • 0030580940 scopus 로고    scopus 로고
    • Evidence that mammalian cells possess homologous recombinational repair pathways
    • [51] L.H. Thompson, Evidence that mammalian cells possess homologous recombinational repair pathways, Mutation Res. 363 (1996) 77-88.
    • (1996) Mutation Res. , vol.363 , pp. 77-88
    • Thompson, L.H.1
  • 52
    • 0030575544 scopus 로고    scopus 로고
    • Molecular biology of DNA repair in the fission yeast Schizosaccharomyces pombe
    • [52] A.R. Lehmann, Molecular biology of DNA repair in the fission yeast Schizosaccharomyces pombe, Mutation Res. 363 (1996) 147-161.
    • (1996) Mutation Res. , vol.363 , pp. 147-161
    • Lehmann, A.R.1
  • 53
    • 0029395076 scopus 로고
    • Menage 'a trois: Double strand break repair, V(D)J recombination and DNA-PK
    • [53] P.A. Jeggo, G.E. Taccioli, S.P. Jackson, Menage 'a trois: double strand break repair, V(D)J recombination and DNA-PK, Bioessays 17 (1995) 949-957.
    • (1995) Bioessays , vol.17 , pp. 949-957
    • Jeggo, P.A.1    Taccioli, G.E.2    Jackson, S.P.3
  • 54
    • 0000489362 scopus 로고
    • DNA repair capacity (DRC) as a biomarker of human variational responses to the environment
    • J.M. Vos (Ed.), Landes Co.
    • [54] L. Grossman, Q. Wei, DNA repair capacity (DRC) as a biomarker of human variational responses to the environment, in: J.M. Vos (Ed.), DNA Repair Mechanisms: Impact on Human Diseases and Cancer, Landes Co., 1994, pp. 329-347.
    • (1994) DNA Repair Mechanisms: Impact on Human Diseases and Cancer , pp. 329-347
    • Grossman, L.1    Wei, Q.2
  • 55
    • 0028912863 scopus 로고
    • Familial clustering of breast cancer: Possible interaction between DNA repair proficiency and radiation exposure in the development of breast cancer
    • [55] K.J. Helzlsouer, E.L. Harris, R. Parshad, S. Fogel, W.L. Bigbee, K.K. Sanford, Familial clustering of breast cancer: possible interaction between DNA repair proficiency and radiation exposure in the development of breast cancer, Int. J. Cancer 64 (1995) 14-17.
    • (1995) Int. J. Cancer , vol.64 , pp. 14-17
    • Helzlsouer, K.J.1    Harris, E.L.2    Parshad, R.3    Fogel, S.4    Bigbee, W.L.5    Sanford, K.K.6
  • 57
    • 0027215352 scopus 로고
    • X-ray-induced chromatid damage in relation to DNA repair and cancer incidence in family members
    • [57] R.D. Knight, R. Parshad, F.M. Price, R.E. Tarone, K.K. Sanford, X-ray-induced chromatid damage in relation to DNA repair and cancer incidence in family members, Int. J. Cancer 54 (1993) 589-593.
    • (1993) Int. J. Cancer , vol.54 , pp. 589-593
    • Knight, R.D.1    Parshad, R.2    Price, F.M.3    Tarone, R.E.4    Sanford, K.K.5
  • 58
    • 0001590339 scopus 로고    scopus 로고
    • Differential sensitivity to benzoapyrene-diol-epoxide (BPDE) as a marker of lung cancer susceptibility
    • [58] X. Wu, J. Gu, T.C. Hsu, W.K. Hong, H. Shi, M.R. Spitz, Differential sensitivity to benzo(a]pyrene-diol-epoxide (BPDE) as a marker of lung cancer susceptibility, Proc. Am. Assoc. Cancer Res. 38 (1997) 618.
    • (1997) Proc. Am. Assoc. Cancer Res. , vol.38 , pp. 618
    • Wu, X.1    Gu, J.2    Hsu, T.C.3    Hong, W.K.4    Shi, H.5    Spitz, M.R.6
  • 60
    • 0029832418 scopus 로고    scopus 로고
    • Reduced DNA repair capacity in lung cancer patients
    • [60] Q. Wei, L. Cheng, W.K. Hong, M.R. Spitz, Reduced DNA repair capacity in lung cancer patients, Cancer Res. 56 (1996) 4103-4107.
    • (1996) Cancer Res. , vol.56 , pp. 4103-4107
    • Wei, Q.1    Cheng, L.2    Hong, W.K.3    Spitz, M.R.4
  • 61
    • 0029193777 scopus 로고
    • Risk factors and genetic susceptibility
    • W.K. Hong, R.S. Weber (Eds.), Kluwer Academic Publishers, Hingham MA, USA
    • [61] M.R. Spitz, Risk factors and genetic susceptibility, in: W.K. Hong, R.S. Weber (Eds.), Head and Neck Cancer, Kluwer Academic Publishers, Hingham MA, USA, 1995, pp. 73-87.
    • (1995) Head and Neck Cancer , pp. 73-87
    • Spitz, M.R.1
  • 63
    • 0028045545 scopus 로고
    • Mutagen sensitivity as a marker of cancer risk
    • [63] M.R. Spitz, T.C. Hsu, Mutagen sensitivity as a marker of cancer risk, Cancer Detect. Prev. 18 (1994) 299-303.
    • (1994) Cancer Detect. Prev. , vol.18 , pp. 299-303
    • Spitz, M.R.1    Hsu, T.C.2
  • 67
    • 0023272175 scopus 로고
    • Reduced DNA repair synthesis in healthy women having first degree relatives with breast cancer
    • [67] E. Kovacs, A. Almendral, Reduced DNA repair synthesis in healthy women having first degree relatives with breast cancer, Eur. J. Cancer Clin. Oncol. 23 (1987) 1051-1057.
    • (1987) Eur. J. Cancer Clin. Oncol. , vol.23 , pp. 1051-1057
    • Kovacs, E.1    Almendral, A.2
  • 68
    • 0031021845 scopus 로고    scopus 로고
    • A versatile and rapid assay of radiosensitivity of peripheral blood leukocytes based on DNA and surface-marker assessment of cytotoxicity
    • [68] N.B. Crompton, M. Ozsahin, A versatile and rapid assay of radiosensitivity of peripheral blood leukocytes based on DNA and surface-marker assessment of cytotoxicity, Radiat. Res. 147 (1997) 55-60.
    • (1997) Radiat. Res. , vol.147 , pp. 55-60
    • Crompton, N.B.1    Ozsahin, M.2
  • 69
    • 0021045810 scopus 로고
    • A genetic component of the variance of N-acetoxy-2-actylaminofluorene-induced DNA damage in mononuclear leukocytes determined by a twin study
    • [69] R.W. Pero, C. Bryngelsson, T. Bryngelsson, A. Norden, A genetic component of the variance of N-acetoxy-2-actylaminofluorene-induced DNA damage in mononuclear leukocytes determined by a twin study, Hum. Genet. 65 (1983) 181-184.
    • (1983) Hum. Genet. , vol.65 , pp. 181-184
    • Pero, R.W.1    Bryngelsson, C.2    Bryngelsson, T.3    Norden, A.4
  • 71
    • 0032519766 scopus 로고    scopus 로고
    • Non-conservative amino acid substitution variants exist at polymorphic frequency in DNA repair genes in healthy humans
    • [71] M.R. Shen, I.M. Jones, H. Mohrenweiser, Non-conservative amino acid substitution variants exist at polymorphic frequency in DNA repair genes in healthy humans, Cancer Res. 58 (1998) 604-608.
    • (1998) Cancer Res. , vol.58 , pp. 604-608
    • Shen, M.R.1    Jones, I.M.2    Mohrenweiser, H.3
  • 72
    • 0031051876 scopus 로고    scopus 로고
    • Cancer predisposition, radiosensitivity and the risk of radiation-induced cancers: III. Effects of incomplete penetrance and dose-dependent radiosensitivity on cancer risks in populations
    • [72] R. Chakraborty, M.P. Little, K. Sankaranarayanan, Cancer predisposition, radiosensitivity and the risk of radiation-induced cancers: III. Effects of incomplete penetrance and dose-dependent radiosensitivity on cancer risks in populations, Radiat. Res. 147 (1997) 309-320.
    • (1997) Radiat. Res. , vol.147 , pp. 309-320
    • Chakraborty, R.1    Little, M.P.2    Sankaranarayanan, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.