Comparison of the expression of a Tα1:nlacZ transgene and Tα1 α- tubulin mRNA in the mature central nervous system

Journal of Comparative Neurology

Volumn 374, Issue 1, 1996, Pages 52-69

  Bamji, Shernaz X ^a   Miller, Freda D ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

cerebral cortex; in situ hybridization; microtubules; neuronal plasticity; transgenic mice

Indexed keywords

ALPHA TUBULIN; MESSENGER RNA;

ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; GENE EXPRESSION REGULATION; MICROTUBULE; NERVE CELL GROWTH; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; RAT; TRANSGENE;

ANIMALS; BRAIN; CEREBRAL CORTEX; GENE EXPRESSION REGULATION; HIPPOCAMPUS; HISTOCYTOCHEMISTRY; IN SITU HYBRIDIZATION; LAC OPERON; MICE; MICE, TRANSGENIC; OLFACTORY PATHWAYS; PROSENCEPHALON; RATS; RATS, SPRAGUE-DAWLEY; RHOMBENCEPHALON; RNA, MESSENGER; TUBULIN;

EID: 0029817913     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9861(19961007)374:1<52::AID-CNE4>3.0.CO;2-M     Document Type: Article

References (57)

1. Al-Shawi, R., J. Kinnaird, J. Burke, and J.O. Bishop (1990) Expression of a foreign gene in a line of transgenic mice is modulated by a chromosomal position effect. Mol. Cell. Biol. 10:1192-1198.
2. Austin, C.P., and C.L. Cepko (1990) Cellular migration patterns in the developing mouse cerebellar cortex. Development 110:713-732.
3. Basi, G.S., R.D. Jacobsen, I. Virag, J. Schilling, and J.H.P. Skene (1987) Primary structure and transcriptional regulation of GAP-43, a protein associated with nerve growth. Cell 49:785-791.
4. Bendotti, C., A. Servadio, and R. Samanin (1991) Distribution of GAP-43 mRNA in the brainstem of adult rats as evidenced by in situ hybridization: Localization within monoaminergic neurons. J. Neurosci. 11:600-607.
5. Benze'ev, A., S.R. Farmer, and S. Penman (1979) Mechanism of regulating tubulin synthesis in cultured mammalian cells. Cell 17:319-325.
6. Caron, J.M., A.L. Jones, and M.W. Kirschner (1985) Autoregulation of tubulin synthesis in hepatocytes and fibroblasts. J. Cell Biol. 101:1941-1952.
7. Causing, C.G., K.D. Makus, Y.L. Ma, F.D. Miller, and W.F. Colmers (1995) Selective upregulation of Tα1 α-tubulin and neuropeptide Y mRNAs after intermittent excitatory stimulation in adult rat hippocampus in vivo. J. Comp. Neurol. 367:132-146.
8. Chang, F.L., and W.T. Greenough (1984) Transient and enduring morphological correlates of synaptic activity and efficacy change in the rat hippocampal slice. Brain Res. 309:35-46.
9. Cleveland, D.W., M.F. Pittenger, and J.R. Feramisco (1983) Elevation of tubulin level by microinjection suppresses new tubulin synthesis. Nature 305:738-740.
10. Cleveland, D.W., M.A. Iopata, P. Sherline, and M.W. Kirschner (1988) Unpolymerized tubulin modulates the level of tubulin mRNAs. Cell 25:537-546.
11. Cowan, N.J., P.R. Cobner, E.V. Fuchs, and D.W. Cleveland (1983) Expression of human α-tubulin genes: Interspecies conservation of 3′ untranslated regions. Mol. Cell Biol. 3:1738-1745.
12. Daniels, M.P. (1972) Colchicine inhibition of nerve fiber formation in vitro. J. Cell Biol. 53:164-176.
13. De la Monte, S.M., H.J. Federoff, S.C. Ng, E. Grabczyk, and M.C. Fishman (1989) GAP-43 gene expression during development: Persistence in a distinctive set of neurons in the mature central nervous system. Dev. Brain Res. 46:161-168.
14. Gay, D.A., T.J. Yen, J.Y. Lau, and D.W. Cleveland (1987) Sequences that confer β-tubulin autoregulation through modulated mRNA stability reside within exon 1 of a β-tubulin mRNA. Cell 50:671-679.
15. Gloster, A., W. Wu, A. Speelman, S. Weiss, C. Causing, C. Pozniak, B. Reynolds, E. Chang, J. Toma, and F.D. Miller (1994) The Tα1 α-tubulin promoter specifies gene expression as a function of neuronal growth and regeneration in transgenic mice. J. Neurosci. 14:7319-7330.
16. Graziadei, P.P.C., M.S. Karlan, G.A. Monti-Graziadei, J.J. Bernstein (1980) Neurogenesis of sensory neurons in the primate olfactory system after section of the filia olfactoria. Brain Res. 186:289-300.
17. Harbers, K., D. Jahner, and R. Jaenisch (1981) Microinjection of cloned retroviral genomes into mouse zygotes: Integration and expression in the animal. Nature 293:540-541.
18. Harris, L.W., and D. Purves (1989) Rapid remodelling of sensory endings in the corneas of living mice. J. Neurosci. 9:2210-2214.
19. Herrup, K., and J. Silver (1994) Cortical development and topographic maps: Patterns of cell dispersion in developing cerebral cortex. Curr. Opin. Neurobiol. 4:108-111.
20. Jaenisch, R., D. Jahner, P. Nobis, I. Simon, J. Lohler, K. Harbers, and D. Grotkopp (1981) Chromosomal position and activation of retroviral genomes inserted into the germ line of mice. Cell 24:519-529.
21. Karns, L.R., S.C. Ng, J.A. Freeman, and M.C. Fishman (1987) Cloning of complementary DNA for GAP-43, a neuronal growth-related protein. Science 236:597-600.
22. Korn, R., M. Schoor, H. Neuhaus, U. Henseling, R. Soininen, J. Zachgo, and A. Gossler (1992) Enhancer trap integrations in mouse embryonic stem cells give rise to staining patterns in the chimeric embryos with a high frequency and detect endogenous genes. Mech. Dev. 39:95-109.
23. Krivko, I., and F.D. Miller (1994) NT-3 elicits neuronal growth independent of neuronal survival. Soc. Neurosci. Abstr. 24:42.
24. Kruger, L., C. Bendotti, R. Rivolta, and R. Samanin (1993) Distribution of GAP-43 mRNA in the adult rat brain. J. Comp. Neurol. 333:417-437.
25. Leanza, G., O.G. Nilson, A. Bjorklund (1993) Compensatory changes of in vivo acetylcholine and noradrenaline release in the hippocampus after partial deafferation, as monitored by microdialysis. Brain Res. 615:147-159.
26. Lemischka, I.R., S. Farmer, R. Racaniello, and P.A. Sharp (1981) Nucleotide sequence and evolution of a mammalian α-tubulin mRNA. J. Mol. Biol. 150:101-120.
27. Lewis, S.A., M.G.S. Lee, and N.J. Cowan (1985) Five mouse tubulin gene isotypes and their regulated expression during development. J. Cell Biol. 101:852-861.
28. Lichtman, J.W., L. Magrassi, and D. Purves (1987) Visualization of neuromuscular junctions over periods of several months in living mice. J. Neurosci. 7:1215-1222.
29. Lin, L.H., S. Bocks, K. Carpenter, M. Rose, and J.J. Norden (1992) Synthesis and transport of GAP-43 in entorhinal cortex neurons and perforant pathway during lesion-induced sprouting and reactive synaptogenesis. Mol. Brain Res. 14:147-153.
30. Ma, Y., R.B. Campenot, and F.D. Miller (1992) Concentration-dependent regulation of neuronal gene expression by nerve growth factor. J. Cell Biol. 117:135-141.
31. Mathew, T.C., and F.D. Miller (1990) Increased expression of Tα1 α-tubulin mRNA during collateral and NGF-induced sprouting of sympathetic neurons. Dev. Biol. 141:84-92.
32. Mathew, T.C., and F.D. Miller (1993) Induction of Tα1 α-tubulin mRNA during neuronal regeneration is a function of the amount of axon lost. Dev. Biol. 158:467-474.
33. Mercer, E.H., G.W. Hoyle, R.P. Kapur, R.L. Brinster, and R.D. Palmiter (1991) The dopamine β-hydroxylase gene promoter directs expression of E.coli lacZ to sympathetic and other neurons in adult transgenic mice. Neuron 7:703-716.
34. Miller, F.D., C.C.G. Naus, M. Durand, F.E. Bloom, and R.J. Milner (1987) Isotypes of α-tubulin are differentially regulated during neuronal maturation. J. Cell Biol. 105:3065-3073.
35. Miller, F.D., W. Tetzlaff, M.A. Bisby, J.W. Fawcett, and R.J. Milner (1989) Rapid induction of the major embryonic α-tubulin mRNA, Tα1, during nerve regeneration in adult rats. J. Neurosci. 9:1452-1463.
36. Miller, F.D., A. Speelman, T.C. Mathew, J. Fabian, E. Chang, C. Pozniak, and J. Toma (1994) Nerve growth factor derived from terminals selectively increases the ratio of p75 to trkA NGF receptors on mature sympathetic neurons. Dev. Biol. 161:206-217.
37. Miller, F.D., D. Rogers, S.X. Bamji, R.S. Slack, and A. Gloster (1996) Analysis and manipulation of neuronal gene expression using the Tα1 α-tubulin promoter. Seminars in the Neurosciences 8:117-124.
38. Neve, R.L., N.I. Perone-Bizzozero, S. Finkelstein, H. Zwiers, D.M. Kurnit, and L.I. Benowitz (1987) The neuronal growth associated protein GAP-43 (B-50F1): Neuronal specificity, developmental regulation and regional distribution of the human and rat mRNAs. Mol. Brain Res. 2:177-183.
39. O'Rourke, N.A., M.E. Dailey, S.J. Smith, and S.K. McConnell (1992) Diverse migratory pathways in the developing cerebral cortex. Science 258:299-302.
40. Palmiter, R.D., and R.L. Brinster (1986) Germline transformation of mice. Annu. Rev. Genet. 20:465-499.
41. Paxinos, G., and C. Watson (1986) The Rat Brain in Stereotaxic Coordinates, 2nd Ed. New York: Academic Press.
42. Pickel, V.M., M. Segal, and F.E. Bloom (1974) Axonal proliferation following lesions of cerebellar peduncles: A combined fluorescence microscopic and radioautographic study. J. Comp. Neurol. 155:43-60.
43. Pravtcheva, D.D., T.L. Wise, N.J. Ensor, and F.H. Ruddle (1994) Mosaic expression of an Hprt transgene integrated in a region of Y heterochromatin. J. Exp. Zool. 268:452-468.
44. Purves, D., R.D. Hadley, and J.T. Voyvodic (1986) Dynamic changes in the dendritic geometry of individual neurons visualized over periods of up to 3 months in the SCG of living mice. J. Neurosci. 6:1051-1060.
45. Rakic, P. (1988) Specification of cerebral cortical areas. Science 241:170-176.
46. Scheff, S.W., J.K. Morse, and S.T. DeKosky (1988) Neurotophic effects of steroids on lesion-induced growth in the hippocampus. I. The asteroidal condition. Brain Res. 457:246-250.
47. Skene, J.H.P. (1984) Growth-associated proteins and the curious dichotomies of nerve regeneration. Cell 37:659-667.
48. Steward, O. (1992) Lesion-induced synapse reorganization in the hippocampus of cats: Sprouting of enthorinal, commissural/associational, and mossy fiber projections after unilateral entorhinal cortex lesions, with comments on the normal organization of these pathways. Hippocampus 2:247-268.
49. Steward, O. (1995) The process of reinnervation in the dentate gyms of adult rats: Gene expression by neurons during the period of lesion-induced growth. J. Comp. Neurol. 359:391-411.
50. Strittmatter, S.M., C. Fankhauser, P.L. Huang, H. Mashimo, and M.C. Fishman (1995) Neuronal pathfinding is abnormal in mice lacking the neural growth cone protein GAP-43. Cell 80:445-452.
51. Tetzlaff, W., S.W. Alexander, F.D. Miller, and M.A. Bisby (1991) Response of facial and rubrospinal neurons to axotomy: Changes in mRNA expression for cytoskeletal proteins and GAP-43. J. Neurosci. 11:2528-2544.
52. Vale, R.D., B.J. Schnapp, T. Mitcheson, E. Steuer, T.S. Reese, and M.P. Sheetz (1985) Different axoplasmic proteins generate movement in opposite directions along microtubules in vitro. Cell 43:623-632.
53. Vandaele, S., D.T. Nordquist, R.M. Fedderson, I. Tretjakoff, A.C. Peterson, and H.T. Orr (1991) Purkinje cell protein-2 regulatory regions and transgene expression in cerebellar compartments. Genes Dev. 5:1136-1148.
54. Villasante, A., D. Wang, P. Dobner, P. Dolph, S.A. Lewis, and N.J. Cowan (1986) Six mouse α-tubulin mRNAs encode five distinct isotypes: Testis-specific expression of two sister genes. Mol. Cell. Biol. 6:2409-2419.
55. Wang D., A. Villasante, S.A. Lewis, N.J. Cowan (1986) The mammalian β-tubulin isotype. J. Cell Biol. 103:1903-1910.
56. Wu, W., T.C. Mathew, and F.D. Miller (1993) Evidence that the loss of homeostatic signals induces regeneration-associated alterations in neuronal gene expression. Dev. Biol. 158:456-466.
57. Wu, W., A. Gloster, and F.D. Miller (1994) Tα1 promoter:nlacZ construct is induced during both regeneration and sprouting of mature neurons in transgenic mice. Soc. Neurosci. Abstr. 20:542.