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Volumn 8, Issue 8, 1998, Pages 885-890

Chemo-enzymatic transformations in sensitive systems: Lipase mediated hydrolysis of vancomycin esters

Author keywords

[No Author keywords available]

Indexed keywords

TRIACYLGLYCEROL LIPASE; VANCOMYCIN DERIVATIVE;

EID: 0032554713     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00109-7     Document Type: Article
Times cited : (6)

References (32)
  • 19
    • 0026760182 scopus 로고
    • 19. Neu, H. C. Science 1992, 257, 1064.
    • (1992) Science , vol.257 , pp. 1064
    • Neu, H.C.1
  • 22
    • 84920311598 scopus 로고    scopus 로고
    • note
    • 30,31 Alkoxyamino esters were used to synthesize vancomycin conjugates 5d-e and 6d-e containing alkoxy linkers. Aglycone derivatives were prepared by reacting the aglycone (1 equiv) with 5 equiv dicyclohexylcarbodiimide, 5 equiv of the amine, 2 equiv of hydroxybenztriazole, and 2 equiv of triethylamine or diisopropylethylamine in anhydrous DMSO (20 mL/mmol).
  • 24
    • 84920311597 scopus 로고    scopus 로고
    • note
    • 24. We also observed no reaction for vancomycin benzyl and methyl esters with shorter linking arms.
  • 27
    • 0031149732 scopus 로고    scopus 로고
    • 27. For recent examples, see; Johnson, G. M.; Abarella, J. P.; Petry, C. Bioconj. Chem. 1997, 8, 447; Koyama, Y.; Umehara, M.; Mizuno, A.; Itaba, M.; Yasukouchi, T.; Natsume, K.; Suginaka, A.; Watanabe, K. Bioconj. Chem. 1996, 7, 298.
    • (1997) Bioconj. Chem. , vol.8 , pp. 447
    • Johnson, G.M.1    Abarella, J.P.2    Petry, C.3
  • 29
    • 84920311596 scopus 로고    scopus 로고
    • note
    • ++ at 817.1.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.